Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06288165Recruiting
Sinus reducer trial for persistent chest pain
This study tests a device called the sinus reducer for people with long-lasting chest pain that hasn't improved with medication or other procedures. It may help if you have limited options for treatment.
Lubin, Lower Silesian VoivodeshipAges 18 years+ - NCT06288633Recruiting
Heart nerve ablation for slow heart rhythm
This test uses a procedure to ablate (destroy) specific nerves in the heart that may be causing your heart to beat too slowly. The goal is to help your heart speed up naturally when needed, so you may avoid needing a permanent pacemaker.
Saint PetersburgAges 18–65 - NCT06288906Recruiting
Mechanical Clot Removal for Deep Vein Thrombosis
This trial tests a mechanical device that removes blood clots from deep veins in the pelvis or leg. It may be an option if you have a large clot and are at low risk for bleeding.
Milan, ItalyAges 18 years+ - NCT06289569Recruiting
Home therapy for recovery after stroke-related dementia
This trial tests a home-based therapy program for people who have had a stroke that led to vascular dementia. The therapy focuses on improving arm and hand movement, and it is done remotely with a caregiver's help.
Houston, TexasAges 18–110 - NCT06289985Recruiting
Expanding clot removal for medium vessel strokes
This trial tests a new approach to see if removing clots from medium-sized brain blood vessels can help more patients recover from stroke. It aims to expand the use of a standard clot-removal procedure to people with less severe symptoms or blockages in smaller vessels.
Birmingham, AlabamaAges 18 years+ - NCT06290713RecruitingPhase 2
Blood flow and exercise study for Duchenne muscular dystrophy
This trial tests if a medicine that improves blood flow, combined with exercise, can help muscles in boys with Duchenne muscular dystrophy. It is for boys who can still walk and are on a stable steroid medication.
Gainesville, FloridaAges 6 years+ - NCT06290154Recruiting
Heart health after liver transplant study
This study looks at factors that affect heart health after a liver transplant. It may help doctors better predict and manage heart problems in people with end-stage liver disease who are getting a new liver.
Guangzhou, GuangdongAges 18 years+ - NCT06290544Recruiting
Heart Risk Study for Italian Adults with Type 1 Diabetes
This study looks at heart health in adults with type 1 diabetes. By joining, you'll help doctors better understand how to prevent heart problems in people like you.
MilanAges 18 years+ - NCT06291389Recruiting
Airway pressure changes during tummy tuck surgery
This trial tests how changes in airway pressure during tummy tuck surgery affect breathing after the operation. It is for healthy adults having a tummy tuck with muscle tightening.
Tanta, EgyptAges 20–50 - NCT06291922Recruiting
Home exercise program for LVAD recovery
This study tests a home exercise program using your smartphone after you get a HeartMate 3™ LVAD. It aims to help you get stronger and recover safely at home.
Detroit, MichiganAges 18 years+ - NCT06292117Recruiting
Genotype-guided antiplatelet therapy for stroke patients
This trial tests whether using a rapid genetic test to choose antiplatelet medication can improve outcomes for people who have had a stroke or mini-stroke. The test checks a gene that affects how your body processes a common antiplatelet drug, so your doctors can pick the safest and most effective medicine for you.
Charlottesville, VirginiaAges 18 years+ - NCT06292377Recruiting
Understanding Fatigue After First Stroke
This study looks at why people feel very tired after a first-time stroke. It involves questionnaires, thinking and memory tests, and a brain MRI to understand sleep, mood, and fatigue better.
BrusselsAges 18 years+ - NCT06294119Recruiting
Brain-heart-vessel interaction study in heart surgery patients
This study looks at how your brain, heart, and blood vessels work together during heart surgery. It uses simple tests to measure these connections, which may help doctors better understand your health.
San Donato Milanese, MilanAges 18 years+ - NCT06294028Recruiting
Ablation vs Defibrillator for Well-Tolerated Fast Heartbeat
This study compares two treatments for a fast heartbeat called ventricular tachycardia in people with prior heart attacks and relatively preserved heart function: one uses heat energy (ablation) to fix the electrical problem, and the other places an implantable defibrillator that shocks the heart to restore normal rhythm. The goal is to find which approach works better for people whose symptoms are well-tolerated.
Toulouse, FranceAges 18–90 - NCT06296121RecruitingPhase 3
BCD-264 vs Darzalex for relapsed multiple myeloma
This trial tests a new drug, BCD-264, compared to Darzalex (daratumumab) alone for people with multiple myeloma that has come back or stopped responding to prior treatments. The goal is to see if BCD-264 works better than Darzalex in controlling the cancer.
ChelyabinskAges 18 years+ - NCT06296082RecruitingPhase 2/Phase 3
Dry Needling vs Botox for Post-Stroke Leg Stiffness
This study compares two treatments for leg stiffness after a stroke: dry needling (tiny needles placed in trigger points) and Botox injections. It may help you if you've had a first stroke within the past year and have mild to moderate tightness in the calf muscles that limits ankle movement.
Antwerp, FlandersAges 18–75 - NCT06296368Recruiting
A tool to help older adults make cancer care decisions
This trial tests if a special tool can help adults aged 60 and older who are newly visiting a blood cancer or bone marrow transplant clinic understand their options and make decisions that fit their needs.
Chapel Hill, North CarolinaAges 60 years+ - NCT06296576Recruiting
Testing a new way to predict critical limb ischemia
This trial uses a Doppler ultrasound to measure blood flow speed in your leg arteries to see if it can better predict a severe form of peripheral artery disease called critical limb ischemia. You may qualify if you have known artery disease in your leg and are already scheduled for a toe blood pressure test.
CholetAges 18 years+ - NCT06297707Recruiting
Aquatic strength training for chronic heart failure
This trial tests whether high-intensity resistance training in water can improve strength and function in people with chronic heart failure. It's designed for those who are stable on medication and not yet in a rehab program.
Cairo, DokkiAges 45–60 - NCT06297226RecruitingPhase 2
CAR T cell therapy for multiple myeloma
This trial tests a new CAR T cell therapy (arlocabtagene autoleucel) that targets a protein called GPRC5D on myeloma cells. It is for people whose multiple myeloma has come back or is not responding after trying at least four different types of treatment.
Birmingham, AlabamaAges 18 years+ - NCT06297863RecruitingPhase 2
Head-down position to improve blood flow in stroke
This study tests whether lying with your head tilted down 15 degrees can improve blood flow to the brain during a stroke. It is for people who have a clot in the middle cerebral artery and are already getting a procedure to remove the clot.
AvezzanoAges 18 years+ - NCT06298474Recruiting
BRAIN App for dementia support
This study is testing a new app (BRAIN App) designed to help people with dementia stay connected and engaged. Researchers want to see if the app can be useful for older adults who can still communicate and have not had a recent fast decline in health.
Winchester, MassachusettsAges 65 years+ - NCT06298448Recruiting
Ear, nose, and throat inflammation study in eGPA
This study looks at inflammation in the ear, nose, and throat area in people with different conditions, including nasal polyps, severe asthma, eGPA (a rare blood vessel disease), and GPA (another rare disease). It compares them to healthy volunteers to better understand what causes local inflammation.
GroningenAges 18 years+ - NCT06298864Recruiting
Online anxiety treatment after a heart attack
This study tests an online program to help people reduce anxiety after a heart attack or unstable angina. The goal is to see if the program can improve quality of life and reduce heart-related worries.
StockholmAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.