Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06368193Recruiting
Neuralert Stroke Monitor Pilot Study
This pilot study tests a new stroke-detection device for patients at high risk of stroke while in the hospital, especially after heart or blood vessel surgery. The device monitors for signs of stroke so doctors can respond quickly.
Philadelphia, PennsylvaniaAges 22 years+ - NCT06368206Recruiting
Testing a fingertip light sensor for blood pressure
This study tests a new way to measure blood pressure by using a light sensor on your fingertip, instead of a traditional arm cuff. It aims to see if this optical method works as well as standard blood pressure checks.
LausanneAges 21–85 - NCT06368518Recruiting
Study of hypertrophic cardiomyopathy in Austria
This study tracks people with hypertrophic cardiomyopathy, a heart muscle disease, to learn more about the condition and improve care. It does not test a new treatment but collects health information over time.
Linz, LinzAges 18 years+ - NCT06369051Recruiting
Helping young stroke survivors start their own business
This trial tests a program to help young adults who had a stroke and are currently unemployed start their own business. It aims to understand if support can help them return to work through self-employment.
Hong KongAges 18–64 - NCT06369142Recruiting
Shockwave lithotripsy for severe calcium in heart arteries
This study tests a new method called coronary lithotripsy to break up severe calcium deposits in heart arteries before placing a stent. It may help people with very hard, calcified blockages that are hard to treat with standard stenting.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT06369818Recruiting
Heart output measurement in shock patients on life support
This study tests if a new way of measuring heart function (using sound waves and breath analysis) works well in patients who are in severe heart failure and need a heart-lung machine. It might help doctors better monitor patients after heart surgery.
MünsterAges 18 years+ - NCT06370520Recruiting
Teen emotions screening after mild brain injury
This study screens teens aged 11 to 17 for emotional and mental health problems after a mild traumatic brain injury (mTBI, also called concussion or minor head injury). The goal is to find out if the hospital screening helps identify teens who may need extra support.
Sacramento, CaliforniaAges 11–17 - NCT06371729Recruiting
Comparing two heart mapping methods for VT ablation
This trial tests two different ways of mapping the heart to guide treatment for a dangerous fast heart rhythm. The goal is to see which mapping method works better for people with an ICD who need a procedure called ablation to stop the rhythm.
Milan, LombardyAges 18 years+ - NCT06371976Recruiting
Stress hormone system study after heart surgery
This study looks at how your body's stress hormone system (the HPA axis) works after heart surgery if you develop vasoplegic syndrome (a serious drop in blood pressure). The goal is to understand if giving extra steroids might help. If you are scheduled for heart surgery with a heart-lung machine, you may be able to join.
Paris, Île-de-France RegionAges 18 years+ - NCT06371937Recruiting
Heart and blood vessel disease biobank study
This study creates a collection of skin cells (turned into stem cells in a lab) from people with various heart and blood vessel conditions. It aims to find new ways to understand and treat these diseases.
London, OntarioAges 18–80 - NCT06372730Recruiting
Predicting blood clot return after stopping blood thinners
This study uses a special 3D lung scan (V/Q SPECT/CT) to see if leftover blockages in your lungs can predict if another blood clot will come back. You may be eligible if your doctor has decided it's safe to stop your blood thinners after 3 to 6 months of treatment for a first blood clot.
Amiens, FranceAges 18 years+ - NCT06373601Recruiting
Testing a drug-coated balloon for small heart arteries
This study tests a drug-coated balloon (DCB) that releases two medicines (sirolimus and paclitaxel) to open blocked small heart arteries. It may help people with stable chest pain or recent, controlled heart events who have a narrowed small vessel.
Mercogliano, Italy/AvellinoAges 18 years+ - NCT06374355Recruiting
Semibranch Stentgraft Registry Study
This study looks back at medical records of people who have already received a semibranch stentgraft. It helps doctors learn more about how well the stentgraft works and how people recover after treatment.
MünsterAges 18 years+ - NCT06374277Recruiting
Pharmacy Coaching to Help After Hospital Stay
This study tests a program where a pharmacist helps you manage your medications after you leave the hospital. It is for people with long-term health conditions who want to stay on track with their medicines.
Knoxville, TennesseeAges 18 years+ - NCT06374667Recruiting
Skull bone injection vs. IV for large stroke
This trial tests a new way to give medicine for a large stroke on one side of the brain. The medicine is injected into the skull bone instead of through a vein, and researchers want to see if it works better and is safe.
Wuhu, AnhuiAges 18–80 - NCT06374693Recruiting
Nerve stimulation after brain aneurysm repair
This trial tests whether a gentle nerve stimulation device (tVNS) applied to the ear is safe and practical for patients recovering from a specific type of brain bleed. It aims to see if this non-invasive treatment might help recovery after the aneurysm is repaired.
Sheffield, South YorkshireAges 18 years+ - NCT06375694Recruiting
Probiotic and nitrate: a blood flow study
This study tests if a probiotic supplement can help your body turn nitrates from food into a substance that may improve blood flow. Healthy adults who are comfortable with blood and saliva samples can take part.
Winston-Salem, North CarolinaAges 18–70 - NCT06376630Recruiting
Esmolol for heart protection during heart attack
This study tests if giving a fast-acting heart medication (esmolol) early through an IV can protect the heart muscle during a heart attack. It may help patients who cannot receive a standard treatment due to certain risks.
MoscowAges 18 years+ - NCT06376916RecruitingPhase 3
Testing magnesium doses for fast heart rate in atrial fibrillation
This trial tests whether giving a higher dose of magnesium (4 grams) compared to a lower dose (2 grams) or a placebo can help control a fast heart rate during atrial fibrillation. It may help patients who are already receiving diltiazem.
Oak Lawn, IllinoisAges 18 years+ - NCT06377033Recruiting
Using health records to advance genomic medicine for all
This study uses electronic health records to learn how to improve genomic medicine across a diverse health system. It may help make DNA-based healthcare more accessible and effective for people with certain conditions.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06377449Recruiting
Lung ultrasound for better outcomes after heart surgery
This study tests whether using ultrasound to look at the lungs during and after heart surgery helps improve recovery. You may be eligible if you are having open-heart surgery with a heart-lung machine and meet certain health criteria.
Saint Petersburg, Sankt-PeterburgAges 18 years+ - NCT06377878Recruiting
The Preeclampsia Registry
This study is building a registry of people who have had preeclampsia or related high blood pressure disorders during pregnancy, as well as their family members and healthy volunteers. The goal is to collect information that can help researchers better understand these conditions and improve care.
Melbourne, FloridaAges 13 years+ - NCT06379386Recruiting
Long-term results of TAVR for severe aortic valve regurgitation
This trial follows people who have severe aortic valve regurgitation and get a TAVR. It looks at how well the valve works over time and how patients do in the long run.
Xi'an, ShannxiAges 18 years+ - NCT06379646Recruiting
YTS109 cell therapy for autoimmune disease
This study tests a new cell therapy (YTS109) for people with autoimmune diseases like lupus or Sjogren's syndrome that have not improved or keep coming back after standard treatments. It aims to see if the treatment can help control the disease.
Shanghai, Shanghai MunicipalityAges 18–65
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.