Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06358391Recruiting
Comparing two needles for left atrial access in heart procedures
This trial compares two devices used to create a small opening in the wall between the upper chambers of the heart so doctors can reach the left side to treat heart rhythm problems or other conditions. It may help if you need a left atrial procedure and are healthy enough for the puncture.
Bucheon-siAges 18 years+ - NCT06357754Recruiting
Testing tumor samples after BMS cell therapy and a second cancer
This trial offers testing of tumor samples for people who developed a new, different cancer after receiving a Bristol-Myers Squibb gene-modified cell therapy. The goal is to understand the genetics of that new cancer and see if it relates to the prior treatment.
Portland, OregonAges Any age - NCT06358248Recruiting
Registry for customized endografts in complex aortic aneurysms
This registry tracks patients with complex abdominal aortic aneurysms who receive a physician-modified endograft. It aims to collect data on how well this tailored device works to treat aneurysms that standard grafts cannot handle.
PadovaAges 18–100 - NCT06358313RecruitingPhase 3
Clopidogrel with statins for small vessel stroke
This study tests if combining the blood thinner clopidogrel with either atorvastatin or rosuvastatin (both cholesterol-lowering drugs) works better for people who have had a mild first-time stroke in the small blood vessels of the brain. The goal is to find a safe and effective treatment regimen.
Kafr ash ShaykhAges 18–75 - NCT06359782RecruitingPhase 2
Testing C1-inhibitor for brain bleed after aneurysm
This trial tests a drug called C1-inhibitor (a protein that calms inflammation) given shortly after a bleeding stroke caused by an aneurysm. The goal is to see if it can reduce brain damage and improve recovery.
The Hague, South HollandAges 18 years+ - NCT06360120RecruitingPhase 3
Clopidogrel plus a statin for large-vessel stroke recovery
This study tests whether adding clopidogrel (a blood thinner) to atorvastatin or rosuvastatin (cholesterol-lowering drugs) helps people who had a first-time large-vessel ischemic stroke. It aims to find the best way to prevent another stroke.
Kafr ash ShaykhAges 18–75 - NCT06360627Recruiting
Low-dose CT with contrast for lung checks
This study tests a special low-radiation CT scan with a contrast dye called Iomeron 400 to see if it works well for checking lung nodules or pneumonia.
ZurichAges 18 years+ - NCT06360939Recruiting
Radiation or ablation for ventricular tachycardia in heart disease
This trial compares two treatments—radiation therapy or catheter ablation—for people with structural heart disease who have a type of fast heart rhythm called ventricular tachycardia. It aims to see which approach works better to prevent repeat episodes.
WestmeadAges 18 years+ - NCT06361420Recruiting
Lung-protective breathing during aortic dissection repair
This study tests a special way of using a breathing machine during surgery to protect your lungs. It is for people who are having surgery to fix a tear in the main artery of the heart (acute type A aortic dissection).
Fuzhou, FujianAges 14–70 - NCT06361784Recruiting
Heart-Sparing Radiation for Stage 3 Lung Cancer
This study tests a new way of planning radiation therapy for stage 3 lung cancer. By carefully mapping the heart's structure, doctors aim to protect it from radiation and improve treatment safety.
MilanAges Any age - NCT06362343Recruiting
Personalized dosing study for Xa inhibitor blood thinners
This study looks at how the body processes a certain type of blood thinner (Xa factor inhibitors) to help doctors find the right dose for each person. If you have a blood clot in your lungs and are on long-term treatment, this trial might help improve your care.
Beijing, Beijing MunicipalityAges 18–120 - NCT06362382Recruiting
Home rehab via smartphone for pulmonary hypertension
This study tests whether a home-based exercise program, guided by a smartphone app, can improve your daily life and heart function if you have pulmonary hypertension. You will use a wearable device to track your activity and receive remote support from a medical team.
Beijing, Beijing MunicipalityAges 18–60 - NCT06362746RecruitingPhase 3
Staphylokinase for intermediate high-risk pulmonary embolism
This trial tests a new drug, staphylokinase, to see if it can break up blood clots in the lungs in people with a moderate-high risk pulmonary embolism. The goal is to improve blood flow and reduce the chance of complications.
Barnaul, Altayskiy KrayAges 18 years+ - NCT06363305Recruiting
How capsaicin affects heart health in men and women
This study tests whether the compound that makes chili peppers spicy (capsaicin) affects heart health differently in men and women. If you have high blood pressure but are otherwise healthy, you may be able to join.
Saratoga Springs, New YorkAges 18 years+ - NCT06363604Recruiting
Alcohol injection with ablation for persistent atrial fibrillation
This trial is testing a new approach to treat persistent atrial fibrillation (a type of irregular heartbeat) by combining standard catheter ablation with a special injection of alcohol (ethanol) into certain heart veins. It may help people whose symptoms haven't improved with medication.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT06364358Recruiting
Interactive kidney disease education program for African Americans
This study is testing a computer-based education program for African American patients with chronic kidney disease. It aims to help you better understand your condition and treatment options.
Chicago, IllinoisAges 18–70 - NCT06364449Recruiting
Study on choices for first-time dialysis access
This study looks at how doctors decide which type of hemodialysis access (fistula or graft) to create for patients who need it for the first time. It gathers information from multiple hospitals to help improve future decision-making.
TaipeiAges 18–100 - NCT06364644Recruiting
Reducing heart failure risk in low-income adults with diabetes
This study looks at how low income and diabetes together raise the risk of heart failure. It offers a program to help you manage your health and reduce that risk.
Baltimore, MarylandAges 30–70 - NCT06365099RecruitingPhase 1
Brain state test for arm recovery after stroke
This study tests whether we can use brain scans to predict when your brain is ready to move your weak arm after a stroke. It uses a safe, non-invasive technique called transcranial magnetic stimulation (TMS) to measure brain signals.
Austin, TexasAges 18 years+ - NCT06365138Recruiting
Activity at the time of aortic rupture in aneurysm patients
This study looks at what patients were doing just before their aortic aneurysm ruptured, to help understand possible triggers. It is a simple observational study that asks about your activity at the time of rupture.
AugsburgAges 18 years+ - NCT06365502Recruiting
Preventing future heart attacks with drug-coated balloon
This trial tests whether a balloon coated with medicine (drug-coated balloon) can prevent future heart attacks by treating high-risk plaques in arteries that are not the one that caused your current heart attack. You may qualify if you already had a stent placed and have another mildly blocked artery with certain vulnerable features.
Beijin, Beijing MunicipalityAges 18–80 - NCT06365476Recruiting
Shockwave therapy for arm stiffness after stroke
This trial tests whether shockwave therapy (gentle sound waves) can help relax stiff wrist and finger muscles after a stroke. It is for adults who have had one stroke and have noticeable muscle tightness in their arm.
Taipei, TaipeiAges 18 years+ - NCT06365528Recruiting
Tunneled PICC line in adults in the hospital
This study looks at how well a tunneled PICC (a special long-term IV line) works in adults who need it while in the hospital. It aims to see if it reduces complications compared to standard PICCs, which could mean fewer problems for you.
Porto AlegreAges 18 years+ - NCT06366360Recruiting
Virtual reality treatment for stroke-related neglect
This study tests whether virtual reality training can help people who, after a stroke, have trouble noticing things on one side of their body or space (called unilateral neglect). You would use a VR headset to practice tasks that may retrain your brain's attention.
Saint-MauriceAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.