Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,001 recruiting studies in this area right now.
By phase
- Not applicable7,980
- Phase 2482
- Phase 4481
- Phase 3447
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 388
Top conditions
- Stroke846
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)142
- Acute Ischemic Stroke139
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Minnesota121
- Illinois120
- Maryland120
- Texas118
Recruiting studies9,998 total
- NCT06399809RecruitingPhase 2
Fisetin for better walking in peripheral artery disease
This study tests whether a supplement called fisetin can help reduce leg pain and improve walking ability in people with peripheral artery disease (PAD). If you have PAD and are 50 or older, you may be able to join and help see if fisetin can make walking easier.
Chicago, IllinoisAges 50 years+ - NCT06400290Recruiting
Balloon test to find which artery causes chest pain
This study tests a new way to find which blocked heart arteries are causing your chest pain. During a stent procedure, doctors will briefly block each artery to see which one triggers your symptoms. This might help them decide which blockages to treat.
BasildonAges 18 years+ - NCT06400004RecruitingPhase 3
Lumason infusion vs. bolus for better heart imaging
This trial compares two ways of giving Lumason (an ultrasound contrast agent) to improve images of the left ventricle in people whose initial heart ultrasound was unclear. It may help those with a 'suboptimal' view of the heart's pumping chamber.
West Hills, CaliforniaAges 18 years+ - NCT06400927Recruiting
AI virtual assistant for managing new heart failure
This trial is testing a smartphone-based virtual assistant that uses artificial intelligence to help manage heart failure after you leave the hospital. It is designed for people who are newly diagnosed with heart failure and have moderate symptoms, to see if the AI assistant can help keep them healthy and out of the hospital.
Stevenage, HertfordshireAges 18 years+ - NCT06400940RecruitingPhase 4
Testing a flow-diverting stent for brain aneurysms that returned
This trial tests a special stent (DERIVO) for brain aneurysms that have come back after earlier treatment. It's for people who cannot have other treatments like coiling or surgery.
Saint PetersburgAges 18 years+ - NCT06401564Recruiting
Virtual reality rehab after ischemic stroke
This study tests whether using virtual reality (VR) exercises in the hospital can help people recover arm movement and function after an ischemic stroke. You may be a candidate if you have weakness in one arm and can follow directions.
Stony Brook, New YorkAges 18 years+ - NCT06401616RecruitingPhase 4
Stopping blood thinners after heart surgery for atrial fibrillation
This trial tests whether it is safe for patients with atrial fibrillation to stop taking blood thinners after they have had heart surgery, including closure of the left atrial appendage. The goal is to see if these patients can avoid long-term medication without increasing the risk of stroke.
Copenhagen, Capital RegionAges 18 years+ - NCT06401772Recruiting
Body posture to prevent repeat brain bleed after surgery
This trial tests whether lying in a specific body position after surgery can help prevent a chronic subdural hematoma from coming back. It is for people aged 60 and older who have had a small drainage procedure for this type of brain bleed.
Shanghai, Shanghai MunicipalityAges 60 years+ - NCT06402617Recruiting
Ablation of active spots in atrial fibrillation
This trial is testing a new way to treat atrial fibrillation by using a catheter to target the specific areas in the heart that trigger the irregular heartbeat. If you have persistent atrial fibrillation and haven't had prior catheter ablation, you may be eligible to join.
LondonAges 18–85 - NCT06402851RecruitingPhase 4
Blood thinner or none for atrial fibrillation with dialysis
This trial compares two types of blood thinners (vitamin K antagonists and factor Xa inhibitors) versus no blood thinner in people with atrial fibrillation who are on dialysis or have very advanced kidney disease. It aims to see which option is safest and most effective for preventing strokes and bleeds.
Salvador, Estado de BahiaAges 18 years+ - NCT06402747RecruitingPhase 4
Comparing clopidogrel vs cilostazol for diabetes-related artery thickening
This trial compares two blood-thinning drugs (clopidogrel and cilostazol) to see which one better prevents artery problems in people with diabetes and thickened carotid arteries. It may help you if you have diabetes and are already on stable medications.
Seongnam-si, Gyeonggi-doAges 19 years+ - NCT06403267RecruitingPhase 2
Testing NoNO-42 for moderate to severe ischemic stroke
This study tests a new drug called NoNO-42 for people having a moderate to severe ischemic stroke. You can join if you get clot-busting medicine within 4.5 hours of your stroke and may also have a procedure to remove the clot.
Calgary, AlbertaAges 18–90 - NCT06403475Recruiting
Vagus nerve stimulation for aphasia after stroke
This study tests whether a gentle electrical stimulation on the skin of the ear (called tVNS) can help improve word finding in people with aphasia after a stroke. You will use a computer speech program while receiving the stimulation or a placebo.
SheffieldAges 18 years+ - NCT06403839Recruiting
Dental check before valve surgery to prevent infection
This study tests whether a dental check-up before heart valve surgery can help lower the risk of a serious heart infection after the operation.
OdenseAges 18 years+ - NCT06405594Recruiting
Studying sentence production in aphasia
This study looks at how people with aphasia (language trouble after a stroke) produce sentences, compared to healthy adults. By understanding these brain processes, researchers hope to improve language recovery strategies.
College Park, MarylandAges 18 years+ - NCT06405581Recruiting
Frailty and CPR outcomes in children
This study looks at how being frail (weak or fragile) affects outcomes in children who need emergency CPR. It helps doctors understand risks and improve care for young patients.
Istanbul, UmraniyeAges 18–100 - NCT06405750Recruiting
Study of the left atrial appendage during open-heart surgery
This study looks at a part of the heart called the left atrial appendage during open-heart surgery. It aims to learn more about heart rhythm problems and blood clots, which may help improve future treatments.
CopenhagenAges 18 years+ - NCT06406569Recruiting
Home arm rehab technology for stroke recovery
This study tests new technologies to help people recover arm movement after a stroke. You would use special devices at home with a caregiver's help, and the team will see how well they work for you.
Singapore, SingaporeAges 21–80 - NCT06407830Recruiting
Walking therapy with and without muscle stimulation for stroke recovery
This study tests whether adding electrical muscle stimulation to a walking and movement program helps stroke survivors walk better, become more independent, and improve their quality of life.
Lahore, Punjab ProvinceAges 45–65 - NCT06407947RecruitingEarly Phase 1
CT071 for high-risk newly diagnosed multiple myeloma
This trial tests an experimental therapy called CT071 for people with newly diagnosed, high-risk multiple myeloma. It aims to see if this treatment can help control the disease in people who have certain aggressive features.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06408961Recruiting
EVs in Obesity and Cardiometabolic Disease
This study looks at tiny particles released by cells (called extracellular vesicles, or EVs) in people with obesity and related heart health issues. Researchers want to see if these particles are different in people with obesity and diabetes, which could help find new ways to treat or prevent heart problems.
Boston, MassachusettsAges 18 years+ - NCT06409351Recruiting
Physical activity program for stroke survivors
This trial tests a program to help people who have had a stroke get more physically active. If you are at least 6 months past your stroke, live at home, and can walk, you may be able to join a supported self-management program to build healthy habits.
Singapore, SingaporeAges 21–90 - NCT06409364RecruitingPhase 2
Fludrocortisone for brain aneurysm bleeding recovery
This trial tests a medicine called fludrocortisone to see if it helps people recover after a subarachnoid hemorrhage (a type of brain bleed from an aneurysm). The study is for adults who are already being cared for in an intensive care unit shortly after their aneurysm is treated.
New Lambton Heights, New South WalesAges 18 years+ - NCT06409806Recruiting
Brain retraction monitoring during surgery
This trial monitors brain activity during surgery to see how using a retractor to hold brain tissue still might affect the brain. It may help surgeons understand how to protect the brain during these procedures.
London, Greater LondonAges 16 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,001 recruiting cardiology studies from the U.S. registry right now, out of 15,328 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.