Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,001 recruiting studies in this area right now.
By phase
- Not applicable7,980
- Phase 2482
- Phase 4481
- Phase 3447
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 388
Top conditions
- Stroke846
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)142
- Acute Ischemic Stroke139
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Minnesota121
- Illinois120
- Maryland120
- Texas118
Recruiting studies9,998 total
- NCT06501287Recruiting
Meal fats and heart artery disease in non-diabetic people
This study looks at how fats in your blood after a meal (called triglycerides) might affect the buildup of plaque in your heart arteries. It is for people who have coronary artery disease but do not have diabetes or other major health problems like liver, kidney, or thyroid disease.
SohagAges Any age - NCT06501443RecruitingPhase 4
Study of inclisiran after heart attack or stroke
This study tests a cholesterol-lowering injection (inclisiran) given soon after a heart attack, urgent heart procedure, or stroke. The goal is to see if it helps lower bad cholesterol quickly and safely.
CorrientesAges 18–100 - NCT06501768RecruitingPhase 1/Phase 2
Genistein for heart failure inflammation
This trial tests a natural substance called genistein (found in soy) to reduce inflammation in people with heart failure. It may help your heart work better and feel better.
LjubljanaAges 40–80 - NCT06501872Recruiting
Custom stent-graft for large chest and belly aneurysms
This study tests a special stent-graft, custom-shaped by your doctor to fit your aneurysm while keeping blood flow to important organs like your kidneys and stomach. It's for people with large aneurysms in the chest and belly who cannot safely have open surgery.
Lebanon, New HampshireAges 50–95 - NCT06503016RecruitingPhase 3
Phosphocreatine for medical emergency team patients
This study tests if a medicine called phosphocreatine helps people in the hospital who have a serious heart or lung emergency. It aims to see if the medicine can improve recovery and prevent further complications.
MilanAges 18 years+ - NCT06503107RecruitingPhase 1/Phase 2
Nanobody-based CAR-T cells for multiple myeloma
This trial tests a new type of CAR-T cell therapy that targets a protein called BCMA on your myeloma cells. It is for people with multiple myeloma that has not responded to or has come back after several prior treatments.
Wuhan, HubeiAges 18–75 - NCT06503484Recruiting
Brain training with light for stroke arm recovery
This trial tests whether a brain-computer interface (BCI) using near-infrared light can help stroke survivors improve hand and arm movement. You'll receive a type of brain training called neurofeedback during the study.
Hong Kong, Hong KongAges 18–75 - NCT06504238Recruiting
Non-invasive monitoring for acute brain injury
This trial tests special cameras and sensors that check your brain without surgery. It may help doctors watch for brain swelling and other problems more safely.
Boston, MassachusettsAges 18 years+ - NCT06504576RecruitingPhase 2
Testing cilostazol to clear brain bleed
This clinical trial tests whether a medication called cilostazol can help the body reabsorb a brain bleed (intracerebral hemorrhage) more quickly. It is for adults with a small bleed in a specific part of the brain (thalamus or basal ganglia) who are otherwise in good health.
Taipei, Not Required For This CountryAges 20–80 - NCT06504914Recruiting
A lifestyle program for Black female breast cancer survivors
This study tests a lifestyle program designed for Black women who have survived breast cancer. It aims to help with high blood pressure or weight management by teaching healthy cooking and habits.
Chicago, IllinoisAges 18–99 - NCT06504836Recruiting
Walking feedback in stroke recovery
This study tests a special walking feedback system (like a video game for your legs) for people who had a stroke at least 6 months ago. It aims to improve walking quality, such as how smoothly and evenly you step.
TaipeiAges 20–80 - NCT06505109Recruiting
Better sleep and less stress for heart rehab patients
This study is testing a new program to help people in cardiac rehab improve their sleep and manage stress. It uses simple techniques and trackers to see if better rest and less stress can help your heart recovery.
Eindhoven, North BrabantAges 18 years+ - NCT06505369RecruitingPhase 2
Immune therapy for newly diagnosed multiple myeloma before stem cell transplant
This trial tests a type of immune therapy called bispecific T-cell redirectors combined with standard medicines for people newly diagnosed with multiple myeloma who are eligible for a stem cell transplant. The goal is to see if this treatment helps control the cancer better.
CopenhagenAges 18–70 - NCT06505668Recruiting
Comparing two heart rate medicines for clozapine users
This study compares two medications (atenolol and ivabradine) to see which one better controls a fast heart rate (tachycardia) in people with treatment-resistant schizophrenia who are taking clozapine. The goal is to find a safer way to manage this side effect.
Bhubaneswar, OdishaAges 18–60 - NCT06505798Recruiting
Ablation vs medication for heart failure with atrial fibrillation
This trial compares a procedure called ablation (using cold, heat, or electric pulses to fix irregular heartbeats) with standard medications to see which better treats heart failure in people who also have atrial fibrillation. It may help if your heart's pumping ability is reduced and you still have symptoms despite medications.
HalifaxAges 18 years+ - NCT06506071Recruiting
Advanced CT scan for recent heart damage
This study uses advanced CT scans to better understand different types of acute heart muscle damage, such as heart attacks without blocked arteries, inflammation, or stress-related damage. It may help your doctors get clearer images of your heart to guide your treatment.
SalamancaAges 18 years+ - NCT06506448Recruiting
Studying non-blocked arteries after a heart attack
This study looks at arteries in the heart that aren't the one that caused the heart attack. It uses a special CT scan to understand these arteries better in people who have already had a procedure to open the blocked artery.
Bournemouth, DorsetAges 18–85 - NCT06506630Recruiting
Coenzyme Q10 for metabolic syndrome risk
This trial tests whether taking Coenzyme Q10, a natural supplement, can improve heart health markers in people who have or are at high risk for metabolic syndrome. Metabolic syndrome is a group of conditions like high blood sugar, high blood pressure, and belly fat that raise your risk for heart disease and diabetes.
ShenzhenAges 30–90 - NCT06506734Recruiting
Dental color changes and quality of life in early jaundice
This study looks at how early and long-lasting jaundice (high bilirubin levels) affects tooth color and quality of life in children with certain liver conditions. It aims to understand these effects to improve care.
BordeauxAges 12–18 - NCT06507007Recruiting
Inner ear function in Turner syndrome
This study looks at why some people with Turner syndrome have inner ear problems. It uses MRI and CBCT scans to understand the genetic and epigenetic causes.
HerningAges 18–60 - NCT06507488Recruiting
Daphnetin Capsule for Mild Cognitive Issues From Blood Vessels
This trial tests a capsule called daphnetin for people with mild thinking and memory problems linked to blood vessel health. The goal is to see if it helps improve or slow down these changes.
Shenyang, LiaoningAges 50–80 - NCT06507657RecruitingEarly Phase 1
Empagliflozin for heart health in older adults
This study tests whether a medication called empagliflozin (a diabetes drug) can improve heart function in older adults with high blood pressure and obesity who are at risk for heart failure but do not have it yet. You would take the pill daily and have heart ultrasounds to check your heart's health.
Minneapolis, MinnesotaAges 60 years+ - NCT06508866Recruiting
Studying heart rhythm changes after TAVI procedure
This trial looks at how the heart's electrical system may change after TAVI, a procedure to replace a narrowed aortic valve. It aims to better understand these changes to improve care for future patients.
Rozzano, MilanoAges 18 years+ - NCT06508983RecruitingPhase 3
SG301 for multiple myeloma returning after treatment
This trial tests a new drug called SG301 added to standard treatments (pomalidomide and dexamethasone) for people with multiple myeloma that came back or got worse after prior therapy. It may help if you have tried lenalidomide and a proteasome inhibitor but your cancer is still active.
Beijing, Beijing MunicipalityAges 18–75
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,001 recruiting cardiology studies from the U.S. registry right now, out of 15,328 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Skin
- Blood & lymphatic
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.