Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT06846905Recruiting
Cost and effects of raising the dose of myeloma drugs at home vs. hospital
This study compares whether raising the dose of your current bispecific antibody is more cost-effective when done as an outpatient (day hospital) or as an inpatient. It aims to find the best way to manage your treatment safely.
ToulouseAges 18 years+ - NCT06847074Recruiting
Sleep better after stroke with a morning exercise program
This study tests whether a morning exercise program can help improve sleep quality in people who had a stroke at least a year ago. If you're 55 or older and have trouble sleeping, this trial may be a good fit.
Vancouver, British ColumbiaAges 55 years+ - NCT06847568RecruitingPhase 3
Adrenaline during heart artery procedure to prevent poor blood flow
This study tests whether giving adrenaline (a medicine that helps blood vessels relax) directly into the heart artery during a procedure to open a blocked artery can prevent a complication called 'no reflow' (where blood still doesn't flow well after the blockage is cleared). It is for people having a specific type of heart attack (STEMI) and being treated within 12 hours.
CairoAges 18 years+ - NCT06847633Recruiting
Digital lifestyle program to prevent heart disease
This trial tests a digital program to help people aged 40–60 make healthy changes like eating better, moving more, or managing stress. It’s designed to prevent heart problems before they start.
GävleAges 39–61 - NCT06847932Recruiting
AI ECG to detect early atrial fibrillation
This trial uses an artificial intelligence system to analyze your electrocardiogram (ECG) results and alert your care team if you might be developing atrial fibrillation. It aims to catch this common heart rhythm problem early, so you can get treatment sooner.
TaipeiAges 1 month–3 months - NCT06848894Recruiting
Study of a drug for stroke patients after blood clot treatment
This trial tests if adding a drug called human urinary kallidinogenase (HUK) can improve recovery for people who have had a stroke and already received clot-busting medicine or a procedure to remove the clot. The goal is to see if it helps reduce disability after a stroke.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06849505Recruiting
Brain stimulation with movement training for stroke recovery
This trial tests if combining transcranial magnetic stimulation (TMS) with arm and hand exercises helps people recover upper limb function after a first stroke. It is for adults who can follow instructions and have no metal in their head or a pacemaker.
Shanghai, Shanghai MunicipalityAges 20–80 - NCT06849635Recruiting
Cera ASD closure device long-term follow-up study
This study follows up with patients who already received the Cera ASD occluder device to close a hole in the heart (atrial septal defect). It looks at how well the device is working over time and checks for any late problems.
MyszkówAges Any age - NCT06849752Recruiting
Early heart failure screening for high-risk patients
This trial checks for early signs of heart failure in people who have multiple risk factors. It will use blood tests, a wearable device, and a handheld ultrasound to find any changes early, so treatment can start quickly.
Cleveland, OhioAges 40 years+ - NCT06849908RecruitingPhase 2
Baricitinib for treating intestinal Behçet's disease
This trial tests baricitinib, an oral medication, for people with intestinal Behçet's disease that hasn't improved with standard treatments. It aims to see if baricitinib can reduce symptoms and help heal gut ulcers.
Beijing, Beijing MunicipalityAges 18–65 - NCT06850662Recruiting
Backward walking observation training for stroke recovery
This trial tests whether watching videos of backward walking and then practicing it can help improve your walking quality after a stroke. It is designed for people who are at least six months past their stroke and can already walk independently.
TaipeiAges 20–80 - NCT06851949RecruitingPhase 2
Vsling device for ventricular repair in heart failure
This trial tests a new device called Vsling, which is placed inside the heart to help reshape the main pumping chamber (left ventricle) in people with heart failure. It may improve your heart's strength and reduce symptoms like shortness of breath.
Be’er Ya‘aqovAges 18 years+ - NCT06852079RecruitingPhase 3
Testing a herbal pill for mild to moderate high blood pressure
This study tests if a traditional herbal pill called Qurs e Fishar can safely lower blood pressure in adults with mild to moderate hypertension. It may be an option for people looking for natural treatments.
Karachi, SindhAges 30–60 - NCT06852209Recruiting
Brain training with neurofeedback after a stroke
This study tests a brain-training technique called neurofeedback to see if it can improve thinking skills after a stroke. If you have ongoing memory or attention problems despite recovery, this trial may help you train your brain using real-time feedback from your own brain activity.
BordeauxAges 18–75 - NCT06852976RecruitingPhase 2
Gel treatment for diabetic foot ulcers study
This trial tests a new gel (MDI-1228-mesylate) applied to diabetic foot ulcers to see if it helps them heal faster than standard care alone. It is for people who have had a foot ulcer for at least 12 weeks and are already receiving standard treatment.
Durham, North CarolinaAges 18–75 - NCT06853223RecruitingPhase 2
Immune drug to prevent lung transplant failure
This trial tests an immune-suppressing medicine to stop a serious complication called primary graft dysfunction that can happen soon after a lung transplant. It may help people who are already on the transplant waiting list and plan to receive a standard anti-rejection drug regimen.
San Francisco, CaliforniaAges 18 years+ - NCT06853535RecruitingPhase 3
Personalized antiplatelet therapy after stroke or TIA
This study tests whether guiding antiplatelet medication with a blood test can help prevent another stroke or TIA. It looks at people who have had a mild stroke or high-risk TIA within the last 48 hours.
Chengdu, SichuanAges 18 years+ - NCT06853951RecruitingPhase 3
Protecting hearts during chemotherapy in children
This trial tests whether a medication can prevent heart damage in children and teens receiving chemotherapy. It is for patients aged 2 to 18 who can take oral medication.
CairoAges 1–18 - NCT06854484Recruiting
AVEIR leadless pacemaker UK registry study
This study is an observational registry for people who have or will receive an AVEIR leadless pacemaker. It collects information to help doctors understand how the device performs over time.
London, UKAges 18 years+ - NCT06854640RecruitingPhase 1
Safety and dosing study for a new sepsis-related blood clotting treatment
This study tests a new drug (BAY 3389934) for people with sepsis who also have a blood clotting problem. It aims to find the right dose and make sure the drug is safe.
EdegemAges 18–80 - NCT06854978Recruiting
Video game arm rehab at home for stroke recovery
This study tests a home-based video game program designed to help people with stroke improve arm and hand movement. If you have some movement in your affected arm and can use a computer, this trial may help you regain function through engaging, game-like exercises.
West Orange, New JerseyAges 20–80 - NCT06855108RecruitingPhase 3
Caffeine for newborn brain injury after oxygen loss
This trial tests if giving caffeine to newborns who had low oxygen at birth can help protect their brains. It compares caffeine plus standard care to placebo plus standard care for moderate to severe hypoxic ischemic encephalopathy (HIE).
SaidpurAges Up to 6 hours - NCT06855121Recruiting
Norwegian immunotherapy study for multiple myeloma patients
This study collects information from people with multiple myeloma, plasma cell leukemia, or AL-amyloidosis who are about to start a new type of immunotherapy. It helps doctors understand how these treatments work in real life.
ArendalAges 18 years+ - NCT06855537RecruitingPhase 4
Stent for vulnerable plaques in heart patients
This trial tests whether implanting stents in non-obstructive, high-risk plaques (thin-capped fatty plaques) can prevent future heart attacks. It is for people who have already had treatment for a recent heart attack or unstable angina and have additional plaques that are not severely blocking blood flow but are vulnerable.
Beijing, Beijing MunicipalityAges 18–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.