Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT07103057Recruiting
HCM screening registry for people with flagged ECGs
This registry study collects information from people whose ECG tests were flagged by a special computer program as possibly showing hypertrophic cardiomyopathy (HCM), a condition where the heart muscle thickens. It helps doctors learn more about how well the program works and how it affects patient care.
Atlanta, GeorgiaAges 18 years+ - NCT07103317Recruiting
Understanding heart blood flow in chest pain without blockages
This study looks at people who have chest pain but don't have major blockages in their heart arteries. It aims to understand how the tiny blood vessels and artery spasms might be causing symptoms, using special heart tests.
Prague, Česká RepublikaAges 18 years+ - NCT07104487RecruitingPhase 2
PET/MRI scan to detect inflammation in carotid artery disease
This study tests whether a special type of PET/MRI scan can help doctors see inflammation in the carotid artery after a stroke or mini-stroke. By using a radioactive tracer, the scan may identify which patients have dangerous plaque buildup that could lead to another stroke.
Leuven, Vlaams-BrabantAges 18 years+ - NCT07104721RecruitingPhase 1
YTS109 cell therapy for severe autoimmune diseases
This trial tests a new cell therapy called YTS109 for people with severe autoimmune diseases that have not responded to standard treatments. The goal is to see if it can reset the immune system and reduce disease activity in conditions like lupus, Sjögren's syndrome, and others.
Hefei, AnhuiAges 18–65 - NCT07105007Recruiting
Heart health program for older adults living with HIV
This study tests a special program to help people living with HIV improve their heart health through activity and healthy habits. If you have early signs of heart trouble and are not currently very active, this support may help you feel better and reduce your risk.
Seattle, WashingtonAges 40 years+ - NCT07105059RecruitingPhase 1
Teclistamab and mezigdomide for multiple myeloma
This trial tests a combination of two drugs—teclistamab (an immunotherapy) and mezigdomide (a targeted pill)—for people with multiple myeloma that has come back or not responded to previous treatments. The goal is to see if this new combination can help when other options have stopped working.
Basking Ridge, New JerseyAges 18 years+ - NCT07105358Recruiting
Vision recovery study after brain damage
This study tests whether the brain can improve vision after damage caused by stroke, tumor, or injury. It may help people with vision loss from a brain lesion find new ways to see better.
Washington D.C., District of ColumbiaAges 18 years+ - NCT07105943Recruiting
Exercise intensity study for heart attack recovery
This trial is testing different ways of doing exercise during cardiac rehab to see which helps people feel better and stay active. It's for people who have had a heart attack or similar event in the last year and are considered low risk.
LeiriaAges 18 years+ - NCT07106684RecruitingPhase 2
Stem cell transplant with car-t and bi-specific antibody for plasma cell leukemia
This trial tests a treatment plan for newly diagnosed plasma cell leukemia that involves a stem cell transplant followed by two types of immunotherapy: CAR-T cells targeting BCMA and a bi-specific antibody targeting GPRC5D. The goal is to see if this approach can help keep the cancer in remission.
Tianjin, Tianjin MunicipalityAges 18–70 - NCT07106710RecruitingPhase 2
Stem cell transplant plus two targeted therapies for ultra-high-risk myeloma
This trial tests a stem cell transplant followed by two targeted therapies — a BCMA CAR-T and a GPRC5D/CD3 bispecific antibody — to treat newly diagnosed multiple myeloma that has ultra-high-risk features. The goal is to see if this combination can better control the disease.
Tianjin, Tianjin MunicipalityAges 18–70 - NCT07106736RecruitingPhase 2
CAR-T for newly diagnosed multiple myeloma without transplant
This trial is testing a new immunotherapy treatment using CAR-T cells for people with newly diagnosed multiple myeloma who cannot have a stem cell transplant. The treatment aims to target and destroy myeloma cells that have BCMA and GPRC5D proteins on their surface.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT07106879Recruiting
Pre-screening for future metabolic and psychiatric studies
This study does not test a new treatment. It is a pre-screening program to see if you might qualify for future clinical trials on metabolic conditions (like diabetes or weight issues) or psychiatric health (like depression or anxiety). You will be asked some questions and may do some basic health checks to see which future trials could be a good fit for you.
Brooklyn, New YorkAges 18 years+ - NCT07107295Recruiting
Measuring back muscle thickness in chronic stroke patients
This trial uses ultrasound to measure the thickness of a specific back muscle in people who have had a stroke at least 6 months ago. It aims to understand changes in this muscle after stroke, which may help improve rehabilitation.
AnkaraAges 40–70 - NCT07107529RecruitingPhase 2
Study of daratumumab with teclistamab or talquetamab for frail patients with newly diagnosed multiple myeloma
This trial tests a combination of drugs—daratumumab plus either teclistamab or talquetamab—for people who have just been diagnosed with multiple myeloma and are considered frail. The goal is to see if this treatment is safe and effective for those who may not be strong enough for standard therapies.
Ascoli PicenoAges 18 years+ - NCT07107568Recruiting
Testing ways to check heart arteries before valve replacement
This trial compares different methods to evaluate coronary artery disease in patients planning to have a transcatheter aortic valve replacement (TAVR) for severe aortic stenosis. The goal is to find out if a less invasive approach is as safe and effective as the standard one.
InnsbruckAges 18 years+ - NCT07107971Recruiting
Drug balloon vs. standard care for fatty heart plaques
This study compares a drug-coated balloon (which releases medicine into the artery) with standard medicines alone for treating fatty plaques in the heart arteries. It is for people who have already had a heart attack and a successful opening of a blocked artery.
AmsterdamAges 18 years+ - NCT07108231Recruiting
Breathing muscle training for hospitalized heart failure patients
This trial tests whether training the muscles you use to breathe can help people recover while in the hospital for heart failure. If you are stable enough, you may be able to join.
Rio de Janeiro, Rio de JaneiroAges 18 years+ - NCT07108907Recruiting
Registry study of M-TEER heart valve repair
This registry study follows people who are getting a minimally invasive heart valve repair called M-TEER. It helps doctors learn more about how well the procedure works and how patients recover.
Amsterdam, North HollandAges Any age - NCT07109141Recruiting
Registry of Heart Rhythm Fix Procedures Using Pulsed Field Ablation in Poland
This study tracks people who have a procedure called pulsed field ablation to fix an abnormal heart rhythm (atrial arrhythmia). It's a registry, meaning researchers will collect information to learn more about how well the treatment works and how safe it is.
Wroclaw, Lower Silesian VoivodeshipAges 18 years+ - NCT07109739Recruiting
Breathing muscle training for blood pressure
This study tests if doing daily breathing exercises with a device can help lower blood pressure and improve blood vessel health. It's for people with higher-than-normal blood pressure who are otherwise healthy.
Minneapolis, MinnesotaAges 18 years+ - NCT07109752Recruiting
Mindfulness and heart rehab via eHealth for heart disease
This trial tests a home-based program combining cardiac rehabilitation with mindfulness, delivered through a computer or smartphone. It may help people with coronary heart disease manage stress and improve recovery.
Hong KongAges 18 years+ - NCT07109895Recruiting
Custom Insole with Nerve Stimulation for Diabetic Foot Ulcers
This trial tests a custom insole that uses mild electrical stimulation to help heal diabetic foot ulcers. It aims to reduce pain and improve wound healing compared to standard care.
Lahore, Punjab ProvinceAges 18–60 - NCT07110415RecruitingPhase 4
Yangxinshi tablets for heart disease with reduced heart function
This trial tests whether Yangxinshi tablets can help people with coronary heart disease and some degree of heart failure. It looks at improving heart function and safety over the treatment period.
Haozhou, AnhuiAges 40–80 - NCT07110922Recruiting
Pacing the heart's natural electrical highway: Bachmann bundle pacing study
This trial tests a special way to place a pacemaker lead that may improve heart function by pacing the Bachmann bundle, a key electrical pathway between the upper heart chambers. It is designed for people who already need a pacemaker or an ICD with an atrial lead.
Wilkes-Barre, PennsylvaniaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.