Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT07116876Recruiting
Placental membrane vs standard care for diabetic foot ulcers
This study tests a special wound covering made from donated placental tissue to see if it helps diabetic foot ulcers heal better than usual care. It may be an option for people with diabetes who have a foot sore that hasn't healed after 30 days.
Tucson, ArizonaAges 21–80 - NCT07118046Recruiting
X-ray vs. 3D mapping for balloon AFib ablation
This study compares two ways to guide a balloon-based ablation procedure for atrial fibrillation: using only X-ray (fluoroscopy) versus using a 3D mapping system. The goal is to see if one method is safer or more effective.
Madrid, MadridAges 18 years+ - NCT07118345Recruiting
Checking if early skull surgery helps after a major stroke
This study looks at whether doing a surgery to remove part of the skull (decompressive hemicraniectomy) soon after removing a large blood clot from the brain helps people who have had a very severe stroke. It is for people who have had a stroke caused by a blockage in a major artery and have already had a procedure to open that artery.
BeijingAges 18–75 - NCT07118488Recruiting
New ablation approach for persistent atrial fibrillation with heart issues
This study tests a new way to treat long-lasting atrial fibrillation using focused energy (pulse field ablation) guided by special heart mapping. It may help people who have not improved with medications or have other heart problems like heart failure.
Madrid, MadridAges 18–80 - NCT07118631Recruiting
Emergency surgery for bleeding brain blood vessel malformation
This study tests emergency surgery for patients with bleeding from a brain blood vessel malformation (AVM). It aims to see if urgent surgery can help people with this type of stroke.
BeijingAges 18–70 - NCT07118683Recruiting
Brazilian health study for people with HIV or AIDS
This study is creating a record of chronic health conditions (like heart disease, diabetes, or high blood pressure) in people living with HIV or AIDS in Brazil. Joining helps researchers better understand and care for the health needs of people like you.
Goiânia, GoiásAges 18 years+ - NCT07118930RecruitingPhase 2
Testing sivelestat sodium for heart bypass patients
This trial tests if an anti-inflammatory drug called sivelestat sodium can help people recover after heart bypass surgery. It is for patients having planned bypass surgery on at least two heart arteries.
Nantong, JiangsuAges 18–75 - NCT07119021RecruitingPhase 4
Ultra-early stroke treatment with neuroprotection and clot removal
This trial tests a new approach for treating acute ischemic stroke within 4.5 hours of symptoms starting. It combines a special mobile stroke unit that delivers early brain-protecting medicine with standard clot-busting or clot-removal procedures, to see if this can improve recovery.
BeijingAges 18–80 - NCT07119047Recruiting
Helping stroke survivors adopt healthier habits: A feasibility study
This trial tests a program adapted from Ireland to help people after a stroke adopt healthier habits like exercise, diet, smoking cessation, and medication adherence. It is a small, early study to see if the program works in Brazil.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT07119424Recruiting
SGLT2 inhibitor study for older adults
This study looks at how a class of diabetes and kidney drugs called SGLT2 inhibitors affect older adults. It aims to understand the benefits for your kidneys and metabolism.
Milan, MilanAges 65 years+ - NCT07119528Recruiting
App-based care after heart ablation
This study tests whether a smartphone app can help people recover after a new type of heart ablation called pulse field ablation for atrial fibrillation. It aims to see if the app improves follow-up care and quality of life.
SeoulAges 19 years+ - NCT07119801Recruiting
Shock wave therapy for arm stiffness after stroke
This trial tests whether shock wave therapy can help reduce muscle tightness in the wrist and hand after a stroke. It may be an option if you have had one stroke, are between 35 and 65 years old, and still have stiffness that bothers you.
DenizliAges 35–65 - NCT07119827Recruiting
Personality traits and recovery after brain injury
This study looks at how your personality might affect recovery after a serious brain injury or stroke. You and a family member will answer a short personality questionnaire to see if certain traits are linked to better recovery.
Verona, VRAges 18–80 - NCT07120048Recruiting
Study of the INSPIRIS RESILIA Aortic Valve in real-world use
This study collects information on people who receive the INSPIRIS RESILIA aortic valve as part of their regular care. Researchers want to see how well the valve works in everyday practice.
Heidelberg, Baden-WurttembergAges 18 years+ - NCT07119970Recruiting
NETosis markers for predicting blood clots in MPN
This study looks at certain markers in the blood to see if they can predict blood clots in people with myeloproliferative neoplasms (MPN) like polycythemia vera, essential thrombocythemia, or pre-myelofibrosis. It is only for people who have a specific JAK2 mutation and are at high risk for clots, and who are already enrolled in another trial and a biobank.
AngersAges 18 years+ - NCT07119983Recruiting
Stress ball for pain relief during diabetic foot wound cleaning
This study tests whether squeezing a stress ball during wound cleaning (debridement) can help reduce pain and distress for people with diabetic foot ulcers. If you're having this procedure for the first time and have mild pain or more, this simple technique may offer comfort.
Mersin, TarsusAges 18 years+ - NCT07120334Recruiting
Mobile health app for stroke survivors with prediabetes or diabetes
This trial tests a mobile app that helps people recovering from a stroke who also have prediabetes or type 2 diabetes improve their diet and health. You will use the app for about 12 weeks, and it may help you manage your blood sugar and prevent future strokes.
Honolulu, HawaiiAges 30–65 - NCT07120776Recruiting
PET scan study for chest pain in hypertrophic cardiomyopathy
This trial uses a special PET scan to see if the drug Mavacamten (Camzyos) helps improve blood flow to the heart muscle in people with hypertrophic obstructive cardiomyopathy (HOCM) who have chest pain or shortness of breath. If you already take Mavacamten as part of your usual care, the study will compare your PET scan results before and after treatment.
ManchesterAges 18 years+ - NCT07120789Recruiting
Understanding pulmonary hypertension knowledge questionnaire
This study aims to validate a questionnaire that measures how well patients understand pulmonary hypertension. If you have been diagnosed with Group 1 Pulmonary Arterial Hypertension (PAH) and can read the questionnaire, you may be able to help researchers make sure it's a useful tool.
São Paulo, São PauloAges 18 years+ - NCT07121010Recruiting
How animal vs. plant protein shakes affect your health
This study compares how your body handles different types of protein shakes—one made from animal protein and one from plant protein. The goal is to see how each shake affects your nutrient levels and overall health markers.
Pittsburgh, PennsylvaniaAges 18–65 - NCT07121582Recruiting
Brain rhythm training for arm recovery after stroke
This trial tests a way to retrain your brain's rhythms after a stroke to help you move your arm and hand better. It uses a non-invasive head coil (TMS) to stimulate the brain while you squeeze a grip device.
Chapel Hill, North CarolinaAges 45–80 - NCT07122167Recruiting
Study of a drug-coated stent for blocked leg arteries
This study is testing a new drug-coated stent for blocked arteries in the thigh or behind the knee. It may help people with moderate to severe leg pain or wounds by improving blood flow without needing surgery.
Chrzanów, ChrzanowAges 18–80 - NCT07122336Recruiting
A better way to treat persistent atrial fibrillation
This trial tests a new method to treat persistent atrial fibrillation (a long-lasting irregular heartbeat) to see if it helps patients who haven't been helped by medication. It focuses on cleaning up the back wall of the heart to restore a normal rhythm.
ShanghaiAges 18–80 - NCT07122427Recruiting
Aging of blood vessels in heart bypass patients
This trial looks at how blood vessels age in people who are having heart bypass surgery. It will help doctors understand changes in the artery wall over time.
Saint-Etienne, FranceAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.