Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT07259239Recruiting
Using sonic cracker to treat heart artery calcium buildup
This study tests a new device called a 'sonic cracker' (IVL) to break up hard calcium in your heart arteries during a planned angioplasty (PCI). It aims to see if this approach is safe and works well for people with moderate or heavy calcium buildup.
SingaporeAges 21 years+ - NCT07259499Recruiting
Predictors of emergency visits in frail older adults
This study looks at why frail older adults go to the emergency room. Researchers want to see if blood tests and brain scans can help predict who needs emergency care. Participation involves one interview and having had a recent brain scan and blood work.
Pisa, PisaAges 65 years+ - NCT07259577Recruiting
Vagus nerve stimulation for stroke recovery
This trial tests whether stimulating the vagus nerve can improve arm movement, breathing, and quality of life in people who had a stroke more than 6 months ago. It involves a non-invasive device that gently stimulates a nerve in the neck during therapy sessions.
Istanbul, IstanbulAges 18–70 - NCT07259733Recruiting
Fast control of tough high blood pressure in public clinics
This study tests a fast way to get high blood pressure under control faster for people whose current pills aren't working well enough. It focuses on people who have trouble taking all their medicine as directed (like missing doses).
São Paulo, São PauloAges 18–75 - NCT07259928RecruitingPhase 2
Testing ANXV for diabetic retinopathy or retinal vein occlusion
This trial tests a new drug called ANXV (Annexin A5) to see if it is safe and can help people with diabetic retinopathy or a recent retinal vein occlusion. The goal is to reduce eye damage and improve vision.
LondonAges 18 years+ - NCT07260032Recruiting
Exercise study for PTSD and heart health
This study tests if a supervised exercise program can improve heart health in people with PTSD. It may help reduce your risk of heart disease.
Boston, MassachusettsAges 18–65 - NCT07260071Recruiting
High blood pressure in kids at risk for inherited kidney disease
This study looks for early signs of high blood pressure in children and teens (12–17) who have a parent with ADPKD, a kidney condition. It uses non-invasive tests like blood pressure monitoring and MRI to track kidney health.
LondonAges 12–17 - NCT07260656RecruitingEarly Phase 1
Capsaicin cream for diabetic nerve foot pain
This trial tests a new cream (Capsadyn®) made from chili pepper extract to see if it can reduce nerve pain in the feet caused by diabetes. If it works, it could offer a simple treatment you apply at home.
Roanoke, VirginiaAges 25–75 - NCT07261553Recruiting
Exercises at home for muscle and bone conditions
This study looks at how well people follow a home exercise program for muscle or bone problems. It aims to understand what helps or makes it hard to stick with the exercises.
Konya, KonyaAges 18 years+ - NCT07262528Recruiting
Brain training for hand recovery after stroke
This trial tests a brain-based training method (neurofeedback) to help improve hand movement after a stroke. It is for people who had a stroke in the last 3 months and still have weakness on one side.
RzeszówAges 18–70 - NCT07263035RecruitingPhase 4
Urine sodium-guided diuretic strategy for heart failure
This trial tests a new way to adjust diuretic (water pill) doses based on urine sodium levels in patients hospitalized for worsening heart failure. The goal is to improve fluid removal and get patients home sooner.
Lakeland, FloridaAges 18 years+ - NCT07263113Recruiting
Gum disease and heart health study
This study looks at whether severe gum disease (periodontitis) is linked to stiffer arteries and higher heart risk. If you have advanced gum disease or healthy gums, you may be able to join to help researchers understand this connection.
NantesAges 40–69 - NCT07263139RecruitingPhase 2
Testing AGP100 for CPVT heart condition
This trial tests a new drug called AGP100 for people with CPVT, a genetic heart condition that causes dangerous heartbeats during exercise. The goal is to see if AGP100 can safely reduce these abnormal heart rhythms.
OsloAges 18–75 - NCT07263204Recruiting
AI for diagnosing and predicting hypertrophic cardiomyopathy
This trial uses artificial intelligence to help diagnose and predict outcomes for people with hypertrophic cardiomyopathy (HCM), a condition where the heart muscle becomes thickened. It may help doctors better understand your condition and plan your care.
Hangzhou, ZhejiangAges 18 years+ - NCT07263347Recruiting
DIEP flap breast reconstruction: markers and outcomes
This study looks at how certain body markers change during and after DIEP flap breast reconstruction (rebuilding the breast with your own belly tissue) following mastectomy for breast cancer. It aims to improve outcomes and care for women undergoing this surgery.
Wuhan, HubeiAges 18–70 - NCT07263490Recruiting
Pre-eclampsia Risk in Egg Recipients Study
This study looks at whether women who become pregnant after receiving donated eggs have a higher risk of developing pre-eclampsia (a serious blood pressure condition) during pregnancy. It aims to understand risks so doctors can better support pregnant women.
CopenhagenAges 18 years+ - NCT07263685Recruiting
Study of takhzyro (lanadelumab) for teens and adults with HAE in Saudi Arabia
This study looks at how well Takhzyro (lanadelumab) works for people with a specific type of hereditary angioedema (HAE) that is caused by a C1 inhibitor deficiency. It is for teenagers and adults who have already been taking Takhzyro for at least 6 months.
RiyadhAges 12 years+ - NCT07265986Recruiting
Comparing robotic remote heart ultrasound to standard care for heart failure
This trial tests whether a robot that performs heart ultrasounds from a distance works as well as a standard in-person ultrasound for managing heart failure. It could help people on the island of Marie-Galante get specialist care without traveling.
Grand-BourgAges 18 years+ - NCT07266662Recruiting
Sensory aids and brain stimulation for stroke recovery
This study tests if adding sensory aids or brain stimulation can improve arm and hand movement for people who had a stroke more than 6 months ago. It may help if you have some movement but not full use of your arm.
Lahore, Punjab ProvinceAges 45–56 - NCT07266675Recruiting
Recovery after cardiogenic shock study
This trial looks at what happens to people after they survive a serious heart condition called cardiogenic shock, where the heart suddenly can't pump enough blood. Researchers want to understand recovery and improve care for survivors.
TaipeiAges 18 years+ - NCT07266805RecruitingPhase 3
Oral deucrictibant for preventing and treating angioedema attacks in AAE-C1INH
This trial tests two forms of an oral medication to prevent and treat sudden swelling attacks in people with a rare condition called acquired angioedema due to C1 inhibitor deficiency. It aims to see if the drug can reduce attack frequency and manage acute episodes.
San Diego, CaliforniaAges 18 years+ - NCT07267117Recruiting
Heart valve disease progression and outcomes study
This study is following people with heart valve disease (leaky or narrowed valves) to understand how the disease changes over time and what problems it may cause. It does not test a new treatment, but helps doctors learn more about valve disease progression.
Fuzhou, FujianAges 18 years+ - NCT07267468Recruiting
App and nutrition plan for swallowing recovery after stroke
This study tests a mobile health program combining rehabilitation exercises and a personal nutrition plan to help people recover from swallowing problems (dysphagia) after a stroke. The goal is to see if using the app improves swallowing and quality of life.
Algeciras, CadizAges 18 years+ - NCT07267871Recruiting
Oura Ring Blood Pressure Home Study
This study uses your Oura Ring to see if it can help track your blood pressure. Researchers want to learn how well the ring's sensors can measure changes in your blood pressure over time, which could lead to easier home monitoring.
San Francisco, CaliforniaAges 22 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.