Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT07585175Recruiting
Moving from pediatric to adult heart disease care
This study helps doctors understand how to smoothly transition young people with heart problems they were born with from pediatric (children's) hospitals to adult care. It may help improve care coordination and outcomes as patients grow up.
Ottawa, OntarioAges 18 years+ - NCT07282717Recruiting
Skin cell study for COL5A mutation and aortic aneurysm
This trial collects a small skin sample from adults with a COL5A gene mutation and thoracic aortic aneurysm. Researchers study the skin cells to better understand the condition and explore potential treatments.
San Donato Milanese, ItalyAges 18 years+ - NCT07516288RecruitingPhase 1
Second CAR-DC Cell Infusion for Advanced Heart Failure
This trial tests a second dose of specialized immune cells (called CAR-DC) in patients with severe dilated cardiomyopathy (a weakened heart muscle) who received one dose before but saw their heart function decline back to baseline. The goal is to see if a second dose is safe and can improve heart function when the first treatment's benefits wore off.
Hangzhou, Zhejiang / 浙江Ages 18–75 - NCT07669246Recruiting
How stroke affects body awareness
This study looks at how a stroke changes your ability to feel and understand signals from your own body, like hunger or heartbeat. Researchers want to learn more about this so they can help with recovery.
IstanbulAges 18 years+ - NCT07670728Enrolling by invitation
Comparing two types of leg exercises for stroke patients with knee hyperextension
This trial tests whether open-chain (moving one part freely) or closed-chain (keeping foot on ground) exercises better improve knee hyperextension in stroke survivors. It may help you if you have leg weakness and walk with your knee locked back.
Karachi, SindhAges 7 months–1.2 years - NCT07251140Recruiting
Swallowing study with a new microphone device
This study tests a new microphone device to see if it can help find swallowing problems in people who have had a stroke. If you are already scheduled for a swallowing test, you may be able to take part.
Atlanta, GeorgiaAges 40–85 - NCT07252531Recruiting
BrioVAD heart pump study for advanced heart failure
This trial tests a new heart pump (BrioVAD) for people with very advanced heart failure. It aims to help those who are not getting better with standard treatments or who need extra support like IV medicines or a balloon pump.
RotterdamAges 18 years+ - NCT07252830Recruiting
Finding hidden heart risk with extra imaging tests
This study looks at whether using special scans of the heart and neck arteries can better find people at very high risk for heart problems, compared to just using a standard risk score. You may be eligible if you have high cholesterol and are seeing a heart doctor.
PoitiersAges 40–80 - NCT07253870Recruiting
Nerve stimulation for subacute stroke recovery
This study compares two types of nerve stimulation (one on the ear, one on the neck) to see which helps upper limb movement better in people who had a stroke 3–6 months ago. It may help improve arm and hand function.
Lahore, Punjab ProvinceAges 45–70 - NCT07253974Recruiting
Atrial Fibrillation Stroke Recovery Study
This study follows people who had a stroke linked to atrial fibrillation (an irregular heartbeat) and are in a rehabilitation program. Researchers want to see how recovery goes and what helps patients improve.
BarcelonaAges 18–99 - NCT07254013Recruiting
LBBAP Pacemaker Monitoring with Portable ECG
This study is testing a portable heart monitoring device to help doctors check how well a special pacemaker (LBBAP) is working. It may help people who need a new or upgraded pacemaker or heart device.
Besançon, FranceAges 18 years+ - NCT07254195Recruiting
Home rehab program for arm recovery after stroke
This study tests a home-based program using a device called MindMotion GO to help people who have had a stroke improve arm movement. If you had a first stroke more than a month ago and still have trouble using your arm, this program may help you practice movements at home.
Saint-Genis-Laval, LyonAges 18–85 - NCT07254481RecruitingPhase 1
Safety study of VB19055 in healthy volunteers
This trial tests a new drug (VB19055) in healthy volunteers to see how safe it is and how the body processes it. Participants will be watched closely and may help find the right dose for future studies.
HangzhouAges 18–50 - NCT07254390Recruiting
Vagus nerve stimulation for arm recovery after stroke
This trial tests whether gentle electrical stimulation of the vagus nerve in the ear can improve arm and hand recovery when combined with physical therapy. It is for people who had a stroke within the last 6 months and have some arm weakness but can still move their arm a little.
Montescano, PaviaAges 18 years+ - NCT07254572RecruitingPhase 4
Comparing diabetes drugs for heart health in prediabetes
This trial tests whether certain diabetes medications can help prevent worsening of heart disease in people who have prediabetes (higher than normal blood sugar, but not yet diabetes). It may be a good fit if you have known coronary artery disease and prediabetes.
WarsawAges 18–80 - NCT07255144Recruiting
Ultrafast ultrasound imaging for children's heart conditions
This study tests a new, faster ultrasound technique to see heart structure and blood flow in children with or without congenital heart disease (CHD). It aims to improve imaging without risk, using a short scan during a regular check-up.
Pessac, FranceAges Any age - NCT07255352Recruiting
Tape therapy for safer swallowing after stroke
This trial tests whether a special tape placed on the muscles under your chin can help you swallow more safely after a stroke. If you have swallowing problems after a stroke, this treatment may improve your safety while eating or drinking.
SanliurfaAges 18 years+ - NCT07255898RecruitingPhase 1
Study of BL-M24D1 for multiple myeloma and other blood cancers
This trial tests a new drug, BL-M24D1, for people with multiple myeloma or other blood cancers that have come back or not responded to standard treatments. It aims to see if the drug is safe and effective.
Chengdu, SichuanAges 18 years+ - NCT07257107Recruiting
Vagus nerve stimulation plus robot training for stroke recovery
This trial tests if combining a gentle ear nerve stimulation device with robot-assisted arm training can improve arm function in people who had a stroke more than six months ago.
Istanbul, IstanbulAges 18–70 - NCT07257198RecruitingPhase 3
Aspirin-free care with ticagrelor after a heart attack treated without stents or bypass
This trial tests whether taking ticagrelor (a blood thinner) alone, without aspirin, is safe and effective for people who have had a heart attack and are being treated with medication only (no stents or bypass surgery). It could mean fewer pills and possibly reduce bleeding risks.
Montreal, QuebecAges 18 years+ - NCT07258069Recruiting
Glue injection for chronic subdural hematoma
This trial tests whether injecting a medical glue into a specific artery in the brain can safely treat a chronic subdural hematoma (a collection of blood on the brain's surface) or a recurrent subdural hematoma. This approach may offer a less invasive alternative to traditional surgery.
Kobe, Chuo-kuAges 18 years+ - NCT07258524Recruiting
Vasculitis PET scan trial for heart disease risk
This trial uses a special PET scan to look at inflammation in blood vessels and check heart disease risk in people with active ANCA-associated vasculitis (AAV). It may help doctors understand how to better manage heart health during treatment.
EdinburghAges 18 years+ - NCT07259200Recruiting
Sleep quality after atrial fibrillation ablation
This study looks at how treating AFib with a procedure called catheter ablation might affect your sleep quality. You can join if you have AFib and are already planning to have this procedure, and you also have at least one risk factor for sleep apnea.
Grodzisk MazowieckiAges 18 years+ - NCT07259252Recruiting
Flu vaccine study for heart attack or unstable angina patients
This study tests whether getting a flu vaccine helps people who recently had a heart attack or unstable angina (acute coronary syndrome). It looks at whether vaccination can reduce future heart problems.
Wuhan, HubeiAges 18–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.