Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,051 recruiting studies in this area right now.
By phase
- Not applicable8,025
- Phase 2487
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke855
- Heart Failure567
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation273
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction98
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California466
- Alabama199
- Massachusetts181
- Arizona175
- New York166
- Florida146
- Maryland120
- Minnesota120
- Texas120
- Illinois119
Recruiting studies10,048 total
- NCT07290309Recruiting
Remote exercise program for cancer survivors
This study tests a remote guided exercise program for cancer survivors to see if it helps with recovery and well-being. It is designed for people who have finished their main cancer treatments and are not already exercising a lot.
Fort Collins, ColoradoAges 18 years+ - NCT07290595RecruitingPhase 2/Phase 3
Comparing two medicines for faster nerve block in arm surgery
This study compares two medicines (dexmedetomidine and dexamethasone) added to a numbing drug (ropivacaine) for a nerve block in the collarbone area. The goal is to see which combination works faster and better for pain relief during upper limb surgery.
Sāhīwāl, Punjab ProvinceAges 18–70 - NCT07290634Recruiting
Comparing blood-clotting medicines for trauma patients needing many transfusions
This trial looks at two medicines (PCC and recombinant activated Factor VIIa) that help blood clot, to see which works better for trauma patients who need a lot of blood transfusions. If you have a severe injury and need many blood transfusions quickly, this study may help identify the best treatment.
Jacksonville, FloridaAges 18 years+ - NCT07290751RecruitingPhase 4
Adding tirofiban to clot-busting for stroke patients
This trial tests whether adding a second medicine (tirofiban) to standard clot-busting treatment can help people who are not improving after the first hour. It is for people with a moderate to severe stroke who are not candidates for a clot-removal procedure.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07290842Recruiting
Dietary nitrate for high blood pressure kidney injury
This study tests whether a natural substance found in leafy greens (dietary nitrate) can help protect the kidneys of people with high blood pressure and early kidney damage. It may offer a simple dietary way to slow kidney disease.
HerningAges 18–70 - NCT07291024Recruiting
Vagus nerve stimulation and walking therapy for stroke recovery
This trial tests if pairing vagus nerve stimulation with walking exercises can help people who had a stroke more than six months ago improve their walking speed and mobility.
Rochester, MinnesotaAges 18 years+ - NCT07291219Recruiting
Chronic heart failure patient registry study
This study creates a registry of people with chronic heart failure to track their health over time. It may help researchers learn more about the condition and improve future care.
Pavia, PaviaAges 18 years+ - NCT07291245Recruiting
Kawasaki disease match trial: identifying kids who need treatment
This trial is testing a way to match children with Kawasaki disease to the best treatment. It looks at specific symptoms and fever duration to see if a child qualifies for the study, which may help doctors give the right treatment faster.
San Diego, CaliforniaAges 4 weeks–17 years - NCT07291258Recruiting
Long-term health study of children born to transplant mothers
This study follows children born to mothers who had a solid organ transplant (like kidney, liver, or heart) to learn about their long-term health. It may help doctors understand how to better care for these families.
Groningen, Provincie GroningenAges Any age - NCT07291609Recruiting
Microplastics in heart artery patients
This study looks for tiny plastic particles in the blood of people with chronic heart artery disease. You will have a standard CT scan and an invasive angiogram anyway, and researchers will check your blood samples for microplastics.
CasertaAges 18 years+ - NCT07292909RecruitingPhase 4
Effect of Empagliflozin on Inflammation for Coronary Patients
This trial tests if the diabetes drug empagliflozin can help reduce inflammation in people with stable coronary artery disease who are planning to have a stent placed. It may offer a new way to protect heart health.
Beirut, BeirutAges 18 years+ - NCT07293260RecruitingPhase 3
Olpasiran heart scan study for high Lp(a) patients
This study tests if a medication called olpasiran can lower a type of fat in your blood called Lp(a), which is linked to heart problems. You take the medicine or a placebo and get a special heart scan to see changes in your arteries.
Bridgeport, ConnecticutAges 35–80 - NCT07293338Recruiting
Heart muscle blood flow study for dilated cardiomyopathy
This study looks at how small blood vessels in the heart affect outcomes in people with dilated cardiomyopathy (an enlarged, weak heart). You may qualify if you have heart failure with a weak pump and no significant blockages in your main heart arteries.
Hangzhou, ZhejiangAges 18 years+ - NCT07293364Recruiting
Study of C1-inhibitor test for hereditary angioedema diagnosis
This study checks if a blood test measuring C1-inhibitor function can help diagnose hereditary angioedema (HAE), a rare condition that causes painful swelling episodes. If you or a close family member have had swelling without rash or itching that lasts 1-5 days and doesn't get better with allergy meds, this trial may be for you.
AlgiersAges 12 years+ - NCT07293832Recruiting
Beta-blocker therapy for heart attack patients
This trial tests a heart medication (a cardio-selective beta-blocker) given during a heart attack to see if it reduces damage to the heart muscle. It might help people having their first heart attack who are treated quickly with angioplasty (a procedure to open blocked arteries).
Thessaloniki, ThessalonikiAges 18–80 - NCT07293897Recruiting
Study of Livmarli for Alagille Syndrome and PFIC
This study looks at how well Livmarli works for people with Alagille syndrome or a liver disease called PFIC. It uses data from prescriptions to understand the treatment's effects.
Tokyo, TokyoAges Any age - NCT07294118RecruitingPhase 2
Lidocaine and steroids for pain after brain bleed
This trial tests whether giving a numbing medicine (lidocaine) and steroids into the artery that covers the brain can help reduce pain after a brain bleed. It may be an option for people with a specific type of bleeding who have not had certain brain surgeries or procedures.
Galveston, TexasAges 18–100 - NCT07294625RecruitingEarly Phase 1
Gene therapy for relapsed/refractory multiple myeloma
This trial tests a new gene therapy, LVIVO-TaVec200, for people with multiple myeloma that has returned or not responded to other treatments. The goal is to see if it can help control the cancer.
Zhengzhou, HenanAges 18 years+ - NCT07294937Recruiting
10-year heart health check for people screened in Casablanca
This study checks on people who had a heart health screening 10 years ago to learn more about heart risks and develop a risk score just for Moroccans. Researchers will contact you to see how your heart health is now and what might have changed.
CasablancaAges 40 years+ - NCT07295223RecruitingPhase 3
GLP-1 and SGLT2 drugs for heart attack recovery
This trial tests if combining GLP-1 and SGLT2 medications can reduce inflammation and improve heart function after a heart attack in people with type 2 diabetes and obesity. It looks for patients with a specific type of heart attack, elevated CRP levels, and preserved heart pumping ability.
León, GuanajuatoAges 18 years+ - NCT07295886Recruiting
Cream for Protruding Hemorrhoids
This trial tests a cream containing two medicines (nifedipine and lidocaine) for painful, protruding hemorrhoids. The cream may help reduce pain and swelling. You can join if you have moderate to severe hemorrhoids that come out of the anus and have already started the cream in the last five days.
NaplesAges 18–75 - NCT07296081Recruiting
PET scan study for heart scarring in heart failure
This study uses a special PET scan to look for scarring (fibrosis) in the heart muscle of people with heart failure. It may help doctors better understand why some hearts get stiff or weak.
Coimbra, Coimbra DistrictAges 18 years+ - NCT07296952Recruiting
Improving transportation for diabetic retinopathy patients
This study tests a new way to help people with diabetic retinopathy get to their eye appointments. It aims to make transportation easier for patients who have Medicaid insurance.
Chicago, IllinoisAges 18 years+ - NCT07296965Recruiting
Oral bacteria in carotid artery plaque study
This study looks at the bacteria living in your mouth and whether they are linked to plaque buildup in the carotid artery (the main artery in your neck). If you are already scheduled for surgery to remove that plaque, the researchers will take samples from your mouth and the plaque to compare them.
BudapestAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,051 recruiting cardiology studies from the U.S. registry right now, out of 15,491 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.