Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,062 recruiting studies in this area right now.
By phase
- Not applicable8,033
- Phase 2488
- Phase 4482
- Phase 3452
- Phase 1360
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke856
- Heart Failure567
- Hypertension402
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma329
- Atrial Fibrillation273
- Ischemic Stroke199
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction98
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California466
- Alabama199
- Massachusetts182
- Arizona176
- New York166
- Florida145
- Illinois120
- Maryland120
- Minnesota120
- Texas120
Recruiting studies10,059 total
- NCT07367893Recruiting
Exercise echocardiogram registry for heart disease
This study is creating a registry (a database) of patients who have an exercise echocardiogram, which is a stress test that uses ultrasound to look at your heart during exercise. It aims to better understand and diagnose different types of heart disease.
Yongin, Gyeonggi-doAges 18 years+ - NCT07368062Recruiting
Mental health after a heart rhythm drug in the ICU
This study looks at the long-term mental health of people who received a drug called dexmedetomidine during an electrical storm (a dangerous heart rhythm) in the ICU.
Ottawa, OntarioAges Any age - NCT07368322Recruiting
Y-incision vs. standard surgery for aortic root enlargement
This study tests a new surgical method (Y-incision) to enlarge the aortic root during valve replacement, which may help people with a small valve opening. It compares this technique to standard approaches to see if it can prevent the new valve from being too small.
HaifaAges 18–80 - NCT07368933Recruiting
A drug-coated balloon for heart artery blockages
This trial tests a balloon coated with two drugs to treat narrowed or re-narrowed arteries in the heart. It may help people with chest pain or recent mild heart attacks who need a procedure to open a blockage.
BarcelonaAges 18 years+ - NCT07369765Recruiting
Balloon vs stent for blocked arteries
This trial compares two procedures to open completely blocked coronary arteries: a drug-coated balloon or a drug-eluting stent. It may help patients with a single, medium-length blockage in a large enough artery.
IstanbulAges Any age - NCT07369856Recruiting
Using urine sodium to guide diuretic dosing in heart failure
This trial uses a simple urine test to see if your current water pill dose is right for you. The goal is to find the best dose to reduce symptoms and avoid hospital visits.
Vancouver, British ColumbiaAges 18 years+ - NCT07369895RecruitingPhase 1
A new cell therapy for relapsed or refractory multiple myeloma
This trial tests a new cell therapy (O&D-001) for multiple myeloma that has returned or not responded to previous treatments. It targets specific markers on myeloma cells (BCMA or GPRC5D) and aims to shrink the cancer.
Guangzhou, GuangdongAges 18–75 - NCT07370246Recruiting
Carotid stenting for high-risk carotid surgery patients
This trial tests whether placing a stent in the narrowed carotid artery is a good option for people who are at high risk for the standard surgery (carotid endarterectomy). If you have significant blockages in your neck arteries and certain health or anatomical factors that make surgery riskier, this study may be for you.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07370467Recruiting
MRI study for mitral & tricuspid valve repair
This study uses MRI scans to take detailed pictures of the heart before and after a valve repair procedure. It helps doctors better understand how these new, less invasive treatments affect heart function.
Milan, MilanAges 18 years+ - NCT07370688RecruitingPhase 4
Iron infusion after TAVI for older adults
This trial tests whether giving iron infusions after a TAVI procedure can help patients with iron deficiency feel better and improve their quality of life. It is for older adults who have low iron levels and have already had a successful valve replacement.
Rotterdam, South HollandAges 65 years+ - NCT07371455RecruitingPhase 1
LWP779 safety trial for healthy volunteers
This trial tests a new oral medication called LWP779 in healthy adults to see if it is safe and how the body processes it. It helps determine the right dose for future studies.
AdelaideAges 18–65 - NCT07371663RecruitingPhase 1/Phase 2
TCC1727 combination therapy for advanced solid tumors
This trial tests a new drug, TCC1727, combined with other treatments for people with advanced solid tumors that have stopped responding to standard therapy. It aims to see if these combinations can help shrink or control the cancer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07372027Recruiting
Single-needle return for long-lasting dialysis access
This study compares a new single-needle return technique for your dialysis access (AVF) to the usual two-needle method. It aims to see if using just one needle on your fistula and getting the blood back through a leg vein can help your fistula last longer.
Suzhou, AnhuiAges 18–100 - NCT07372170Recruiting
Blood thinners for preventing another clot in low-risk APS
This study looks at how well blood thinners prevent blood clots from coming back in people with antiphospholipid syndrome (APS) who are considered low risk. It compares two types of medicines: direct oral anticoagulants (DOACs) and vitamin K antagonists.
Madrid, MadridAges 18 years+ - NCT07372196Recruiting
Left bundle branch pacing after myectomy for hypertrophic cardiomyopathy
This trial is testing a new way to pace the heart (left bundle branch pacing) for people with hypertrophic cardiomyopathy who still have a dangerous heart rhythm problem after myectomy surgery. It aims to see if this pacing can reduce the risk of sudden cardiac death.
Novosibirsk, Novosibirsk OblastAges 18–75 - NCT07372326Recruiting
Electronic moxibustion for constipation after stroke
This trial tests if a type of heat therapy called electronic moxibustion, timed according to traditional Chinese medicine principles, can help relieve constipation in people who have had a stroke.
Jinhua, ZhejiangAges 30–80 - NCT07372729Recruiting
Smartwatch program for heart health in overweight adults
This trial tests if a smartwatch app can help people who are overweight and have slightly high blood pressure, sugar, or cholesterol improve their heart health. If you qualify, you'll use a smartwatch to track your activity and get coaching.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07372820Recruiting
Metabolic changes after heart transplant and outcomes
This trial looks at how metabolism changes after a heart transplant and whether those changes affect your long-term health and recovery. It is for people who are planning to have or have already had a heart transplant.
Düsseldorf, North Rhine-WestphaliaAges 18 years+ - NCT07373041Recruiting
Support program for heart failure carers in the UK
This study tests a support program for people who care for loved ones with heart failure. It aims to see if the program helps carers by providing talking support and information, and it may help you if you’re caring for someone with heart failure and are comfortable using a digital device.
BelfastAges 18 years+ - NCT07373145Recruiting
CT scan check after drug-coated balloon treatment
This trial uses CT scans to see how well a special drug-coated balloon works for opening blocked heart arteries. It may be a good option if you have new blockages that are the right size for this treatment.
SeoulAges 19 years+ - NCT07373353Recruiting
A new stent for heart disease
This trial tests a new type of stent (a small mesh tube) for people with heart disease who need a procedure to open blocked arteries. It aims to see if the stent is safe and works well.
Toyoake, Aichi-kenAges 18 years+ - NCT07374263Recruiting
Do heart rhythm drugs pose risks in hospital?
This study looks at whether certain medications that can affect heart rhythm (QT-prolonging drugs) are linked to serious heart problems in adults who were hospitalized. It includes patients admitted to St. Joseph's Healthcare Hamilton or other GEMINI hospitals between 2017 and 2025.
Hamilton, OntarioAges 18 years+ - NCT07374289Recruiting
CPR and life support before hospital in Ostrava
This trial is testing a way to start CPR and emergency life support (ECPR) at the scene of a cardiac arrest in Ostrava. It might help if you or a loved one has a witnessed cardiac arrest that is likely caused by a heart problem, and you're under 70 years old.
Ostrava, Moravian-Silesian RegionAges 18–70 - NCT07374276Recruiting
Brain-computer interface with virtual reality for stroke recovery
This trial tests if combining a brain-computer interface (a device that reads brain signals) with virtual reality (an immersive computer environment) can help improve arm movement after a stroke. It might be a good fit if you had a stroke 6 to 24 months ago and still have some weakness in one arm.
Alcabideche, Lisbon DistrictAges 18–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,062 recruiting cardiology studies from the U.S. registry right now, out of 15,523 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.