Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,066 recruiting studies in this area right now.
By phase
- Not applicable8,037
- Phase 2488
- Phase 4482
- Phase 3452
- Phase 1360
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke856
- Heart Failure566
- Hypertension403
- Cardiovascular Diseases390
- Coronary Artery Disease375
- Multiple Myeloma329
- Atrial Fibrillation273
- Ischemic Stroke199
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension104
- Myocardial Infarction98
- Congenital Heart Disease87
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome83
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital54
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California467
- Alabama198
- Massachusetts181
- Arizona176
- New York166
- Florida145
- Illinois120
- Maryland120
- Texas120
- Minnesota119
Recruiting studies10,063 total
- NCT02791152Recruiting
Exercise and blood pressure monitoring in healthy adults
This study looks at how physical activity and regular blood pressure checks relate to heart health signals on imaging. It’s meant for people without major heart, stroke, diabetes, or serious chronic illnesses to understand early cardiovascular risk.
Singapore, SingaporeAges 21–69 - NCT02260271Enrolling by invitation
Study for newborns with severe oxygen-related brain injury
This trial is for newborn babies who had an oxygen shortage around birth and now have severe brain injury. It aims to test approaches that may help improve outcomes after this kind of early-life brain damage.
Gainesville, FloridaAges 1 day–3 weeks - NCT02473757Enrolling by invitation
Follow-up program for adults previously treated with CAR T
This is a follow-up study for people age 18 or older who previously took part in a CAR T-cell gene therapy trial. It helps researchers check your health over time after that treatment and supports long-term safety and outcomes tracking.
Bethesda, MarylandAges 18 years+ - NCT01803906Enrolling by invitation
Tissue sample study for suspected mitochondrial disorders
This study collects tissue samples to help researchers learn more about mitochondrial disorders—conditions related to how the body makes energy. It may help by improving genetic understanding for families who suspect an inherited cause.
New York, New YorkAges Any age - NCT01759225Enrolling by invitation
Registry study of people with heart and blood vessel disease
This is a registry (a study that collects health information) for people with certain heart and blood vessel conditions. It may help researchers better understand who has these diseases, how they are managed, and outcomes over time.
Tel AvivAges Any age - NCT01654133Enrolling by invitation
Testing branched stent grafts’ effect on blood flow after aortic repair
This study evaluates how well branched stent grafts work after repairing certain large or fast-growing aortic aneurysms (bulges in the main artery). It also checks blood-flow and organ function—especially flow to organs—in the weeks and months after the procedure.
Chapel Hill, North CarolinaAges 18 years+ - NCT00833599Enrolling by invitation
Scan lymph drainage and collect samples for related conditions
This study uses a special light scan after a dye is given to look at how your lymph system drains. It may also include genetic testing for people with a family history of lymph-related disorders to better understand causes.
Houston, TexasAges 3 months+ - NCT00807482Recruiting
Study of lung disease causes in primary ciliary dyskinesia
This study looks at how primary ciliary dyskinesia (PCD—a lifelong problem with tiny lung “sweepers”) affects the lungs. You may be able to join if you strongly seem to have PCD based on symptoms, or if you’re a healthy person with a close family member who has confirmed PCD.
Chapel Hill, North CarolinaAges Any age - NCT00583817Enrolling by invitation
Endovascular repair for thoracic aortic aneurysms and dissections
This study tests whether repairing an enlarged or tearing (dissection) thoracic aorta using a catheter-based procedure can be safer for people who are high-risk for open surgery. It uses specialized stent grafts placed through blood vessels to seal the problem and prevent complications.
Boston, MassachusettsAges 18 years+ - NCT00573027Recruiting
Study of heart pain from small artery heart disease
This trial studies people who have chest pain (angina) due to problems with the heart’s small arteries, not a big blockage. It aims to test whether treatment approaches can help these patients by better understanding the cause of their heart-related symptoms.
Los Angeles, CaliforniaAges 18 years+ - NCT00950430Enrolling by invitationPhase 4
Brain scan study for amyloid plaques in adults
This study uses brain imaging to look for amyloid plaques (abnormal protein deposits) as people age. It may help researchers better understand how these changes develop over time.
Rochester, MinnesotaAges 30–100 - NCT00102544Enrolling by invitation
Tracking Devices to Find Abnormalities During Medical Procedures
This study tests technology that uses imaging scans to help doctors locate and reach abnormalities during surgical or interventional procedures. The goal is to make these image-guided procedures more accurate and safer for patients.
Bethesda, MarylandAges 18–120 - NCT01725763Enrolling by invitation
MRI without contrast to help diagnose pulmonary hypertension
This study uses an MRI scan that does not use contrast dye to better diagnose and sort out pulmonary hypertension (high blood pressure in the lungs). It may help doctors classify your condition more accurately, especially around the time you’re scheduled for a right-heart catheterization.
Graz, StyriaAges 18 years+ - NCT00378924Recruiting
Cardiology health study using blood or cheek swabs
This registry collects health information and samples (a blood draw or cheek swab) from adults to help researchers study heart-related conditions. You may qualify whether or not you currently have heart disease, as long as you can safely provide a sample and consent.
Atlanta, GeorgiaAges 20 years+ - NCT02023060Recruiting
Improving function and quality of life after heart valve repair
This study looks at how a less invasive heart valve procedure affects your day-to-day functioning and overall quality of life. If you’re already being considered for a transcatheter (catheter-based) valve replacement, you may be able to join to help understand what improvements patients experience.
JerusalemAges 18–110 - NCT01571700Enrolling by invitation
Study breathing-heart timing differences in pulmonary hypertension
This study looks at timing mismatches (“dysynchrony”) in the heart and lungs in people with pulmonary hypertension. It may help researchers understand what causes symptoms and how the timing affects heart function.
Stanford, CaliforniaAges 5 years+ - NCT02033811Recruiting
MitraClip registry for severe leaky mitral valve
This registry study follows people who have a severely leaky mitral heart valve and receive MitraClip, a procedure that repairs the valve through the skin. It helps doctors learn how well this treatment works over time for different patients.
DüsseldorfAges 18 years+ - NCT01517425Enrolling by invitation
Using blood stem cells to study heart disease traits
This study uses your blood to create special lab cells (induced pluripotent stem cells) to better understand heart-related differences between people with coronary artery disease and generally healthy older adults. It may help researchers learn what biological traits are linked to heart risk and how those traits work.
La Jolla, CaliforniaAges 18 years+ - NCT01316783Enrolling by invitation
Genetics study of obesity, diabetes, and heart risk
This study looks at genetic differences in adults from African diaspora groups to better understand risks for obesity, type 2 diabetes, and heart disease. You may help scientists learn why these conditions are more common in certain communities.
Bethesda, MarylandAges 18–120 - NCT01460264Enrolling by invitation
A heart-and-lung health study following adults over time
This study follows adults with heart-and-lung health information over time to understand how these conditions change. It may help researchers find patterns that could guide better care in the future.
LundAges 45–75 - NCT02013284Enrolling by invitation
Stool test to see if gut microbes predict heart risk
This study looks at your gut bacteria (from a stool sample) to see whether they can help predict heart risk in people being checked for blocked heart arteries. Your results may help researchers understand who is at higher risk and why.
Rochester, MinnesotaAges 18 years+ - NCT01248533Enrolling by invitation
Screening for abdominal aortic aneurysm in 65-year-old men in Oslo
This study is offering screening to check for an abdominal aortic aneurysm, a bulge in a major blood vessel in the belly. It may help find a problem early so it can be monitored or treated sooner if needed.
Ages 65–65 - NCT00047996Enrolling by invitation
Blood Donation Study for Blood Vessel Research
This study collects blood and urine samples from adults to help researchers understand diseases affecting blood vessels. Your donation helps scientists develop better treatments.
Bethesda, MarylandAges 18–100 - NCT07397923RecruitingPhase 2
Zenicom digital therapy for post-stroke aphasia
This study tests a digital therapy app called Zenicom that may help improve language problems after a stroke. It is for people who had a first stroke in the last 3 months and now have trouble speaking or understanding language.
Seongnam-siAges 19 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,066 recruiting cardiology studies from the U.S. registry right now, out of 15,554 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Mental health
- Digestive system
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- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.