Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,066 recruiting studies in this area right now.
By phase
- Not applicable8,037
- Phase 2488
- Phase 4482
- Phase 3452
- Phase 1360
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke856
- Heart Failure566
- Hypertension403
- Cardiovascular Diseases390
- Coronary Artery Disease375
- Multiple Myeloma329
- Atrial Fibrillation273
- Ischemic Stroke199
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension104
- Myocardial Infarction98
- Congenital Heart Disease87
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome83
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital54
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California467
- Alabama198
- Massachusetts181
- Arizona176
- New York166
- Florida145
- Illinois120
- Maryland120
- Texas120
- Minnesota119
Recruiting studies10,063 total
- NCT06512883RecruitingPhase 3
Testing benralizumab in children with eosinophil diseases
This trial tests a medicine called benralizumab for children with specific eosinophil-driven diseases (EGPA or HES). It aims to see if the drug can help control these conditions.
Aurora, ColoradoAges 6–17 - NCT05478213Recruiting
Study how ventricular tachycardia happens in heart disease
This study looks at what causes a dangerous fast heart rhythm (ventricular tachycardia) in people with ischemic cardiomyopathy and an implanted defibrillator. The goal is to better understand the rhythm so doctors can improve treatment, especially around procedures like catheter ablation.
Atlanta, GeorgiaAges 18 years+ - NCT07614659Recruiting
Heart health screening for adults in Uppsala, Sweden
This study invites residents of Uppsala, Sweden who are turning 50, 55, 60, 65, 70, or 75 to participate in cardiovascular (heart and blood vessel) health screening. The goal is to help identify heart health risks early so you can take steps to stay healthy.
UppsalaAges 50–75 - NCT07550296RecruitingPhase 2
Second IV Clot-Dissolving Treatment for Major Stroke
This trial tests giving a second dose of an IV clot-dissolving medicine (prourokinase) to patients who had a stroke from a large clot but didn't improve enough after the first dose. The goal is to see if a second dose within 6 hours of stroke onset can help more patients recover.
Shenyang, None SelectedAges 18–80 - NCT07500480Recruiting
Home use of a wearable grasping device after stroke
This trial tests if a wearable device that helps open and close the hand can be used at home by people who have weakness after a stroke. It may help improve your ability to grasp objects like a glass or spoon.
ToulouseAges 18 years+ - NCT03215849Enrolling by invitation
Tested pacing device for heart failure with preserved pumping
This trial studies a heart pacing approach in people with heart failure symptoms despite preserved heart pumping. It aims to see whether changing heart timing can improve how you feel and how your heart works during exercise.
CardiffAges Any age - NCT03197363Enrolling by invitation
Long-term study of adults living in Białystok
This study follows adults living in Białystok over time to learn about health and life patterns. If you’re invited to take part and agree, it may help researchers better understand community health.
BialystokAges 20–80 - NCT03253835Enrolling by invitation
MRI heart flow study to understand heart muscle damage
This study uses a special heart MRI to look at blood-flow patterns and how they relate to heart muscle injury. It may help researchers better understand different types of heart damage by comparing people with and without injury.
Graz, StyriaAges 20–80 - NCT03225625Enrolling by invitation
Stem cell, virtual reality, and training after spinal cord injury
This study tests whether stem cell treatment along with virtual reality–based training can improve function after spinal cord injury that is not expected to recover with standard care. It’s designed for adults who are medically stable and can safely complete follow-up assessments.
Coral Springs, FloridaAges 18 years+ - NCT03011541Recruiting
Stem cell treatment for damaged retina or optic nerve
This study looks at stem-cell treatment to help vision in adults whose retina or optic nerve damage is not expected to improve on its own. You may be a candidate if your eye exam shows documented, stable or slowly changing damage and you can safely complete follow-up eye visits.
Westport, ConnecticutAges 18 years+ - NCT03388476Enrolling by invitation
Breathing carbon dioxide measurement to detect lung high blood pressure
This trial tests whether measuring carbon dioxide you breathe out can help detect pulmonary hypertension earlier. It may help doctors spot this lung blood vessel condition sooner, especially around the time you get a heart test.
Giessen, HesseAges 18 years+ - NCT03083405Enrolling by invitation
Study of tooth grinding during sleep
This study is for adults who have been diagnosed with sleep bruxism (tooth grinding during sleep). Researchers want to understand it better using sleep testing, and it may help refine how this condition is evaluated.
WroclawAges 18–70 - NCT03275610Enrolling by invitation
Genetic study in people with past lung blood clots after knee or hip surgery
This study looks at genetic (inherited DNA) markers in people who have had a lung blood clot (pulmonary embolism) after having a hip or knee replacement. The goal is to understand why blood clots may happen again and help improve future risk prediction and care.
Los Angeles, CaliforniaAges 18–70 - NCT02699736Enrolling by invitation
HIV and hepatitis C study in European adults
This study follows people living with HIV who also have hepatitis C antibodies, to better understand how HIV and hepatitis C affect health over time. You may be able to join if you meet the age and enrollment requirements, even if your hepatitis C virus level is currently undetectable.
Buenos AiresAges 16 years+ - NCT02670161Enrolling by invitationPhase 4
Using electronic records to improve care for brain and nerve conditions
This study looks at how doctors use electronic medical records to improve treatment and care for people with certain brain and nervous system conditions. It may help because it tests practice-based approaches across neurology visits.
Evanston, IllinoisAges 18–100 - NCT02402426Enrolling by invitation
Online brain health registry for adults
This study is building an online registry where adults can share information to help researchers find people for future brain research. Joining may help future studies get the people they need.
San Francisco, CaliforniaAges 18 years+ - NCT02725060Enrolling by invitation
Study of autoimmune changes in postural tachycardia syndrome
This trial studies whether an autoimmune (immune system–related) process is involved in postural tachycardia syndrome (POTS), a condition where your heart rate rises when you stand. The study may help researchers understand what causes POTS and how it could be treated or monitored.
Oklahoma City, OklahomaAges 18–50 - NCT02266719Enrolling by invitation
Fenestrated branched stents for complex aortic aneurysms and safety
This trial studies a specialized endovascular (through-the-vessel) repair using fenestrated and branched stents to treat complex aortic aneurysms and related dissections. It aims to track clinical outcomes and how much radiation exposure is used during the procedure to improve safety.
Atlanta, GeorgiaAges 18 years+ - NCT02751060Enrolling by invitation
Blood test for RNA signals to track coronary heart disease
This study checks whether tiny RNA signals found in a blood sample can help identify or monitor coronary heart disease. It may help doctors learn better ways to recognize the condition and track changes soon after symptoms begin.
Wuhan, HubeiAges 18 years+ - NCT02413450Enrolling by invitation
Using patient DNA cells to study inherited heart rhythm risks
This study uses your blood or genetic information to make “iPS cells,” lab-grown cells that can help researchers study inherited heart rhythm problems like LQTS, Brugada syndrome, CPVT, or early repolarization syndrome. It may help improve understanding of why these rhythms happen and guide future treatments.
Baltimore, MarylandAges 18–85 - NCT02621944RecruitingEarly Phase 1
Melatonin for newborns with brain injury after oxygen problems
This early study tests whether giving melatonin to newborns with hypoxic-ischemic encephalopathy (brain injury from not enough oxygen around birth) can help protect the brain while they are cooled (therapeutic hypothermia). It may be most relevant if your baby shows early brain-injury signs and meets specific blood test and birth-history timing criteria.
Gainesville, FloridaAges Up to 6 hours - NCT02814942Recruiting
Testing CRT in people with weak hearts and wide ECG signals
This study looks at whether a device called CRT (Cardiac Resynchronization Therapy) can help people with heart failure who have a weak heart pumping strength and a “wide” electrical signal pattern on an ECG. It may help some people feel better and improve heart function, especially if they are not already on the best standard medicines.
SingaporeAges 18 years+ - NCT02669797Enrolling by invitation
Family-based program to help families eat dinner together
This study offers an intervention focused on family dinners to help children improve their eating habits. It targets children who eat family dinners rarely and have a higher weight range, to see if the program can help improve health over time.
Aurora, ColoradoAges 5–10 - NCT02683681Enrolling by invitation
Create a heart tissue and blood sample registry
This study collects blood and/or heart tissue samples from certain people getting heart procedures or with a long-term heart pump. The goal is to store these samples for future research that may improve care for heart failure.
Ages 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,066 recruiting cardiology studies from the U.S. registry right now, out of 15,554 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.