Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,066 recruiting studies in this area right now.
By phase
- Not applicable8,037
- Phase 2488
- Phase 4482
- Phase 3452
- Phase 1360
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke856
- Heart Failure566
- Hypertension403
- Cardiovascular Diseases390
- Coronary Artery Disease375
- Multiple Myeloma329
- Atrial Fibrillation273
- Ischemic Stroke199
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension104
- Myocardial Infarction98
- Congenital Heart Disease87
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome83
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital54
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California467
- Alabama198
- Massachusetts181
- Arizona176
- New York166
- Florida145
- Illinois120
- Maryland120
- Texas120
- Minnesota119
Recruiting studies10,063 total
- NCT07410481Recruiting
Therapy for PTSD after a cardiac arrest
This study compares two talking therapies for PTSD after a cardiac arrest. One combines mindfulness and acceptance with gradual exposure to difficult memories; the other focuses on present life challenges. Both aim to reduce distress and improve quality of life.
New York, New YorkAges 18–81 - NCT07410494RecruitingPhase 1/Phase 2
Personalized donor cell therapy for advanced solid tumors
This trial tests a personalized cell therapy (CAR-NK) using donor immune cells that are engineered to find and attack one or two markers on advanced solid tumors. It may be an option for people whose tumors have these specific markers and have exhausted other treatments.
Beijing, Beijing MunicipalityAges 8–85 - NCT07410624Recruiting
Kidney function in brain injury patients
This trial measures how quickly the kidneys clear drugs in patients with serious brain conditions like stroke or meningitis. It may help doctors adjust medicine doses for better treatment.
Lexington, KentuckyAges 18–85 - NCT07411079Recruiting
Testing clot-busting drug on brain bleed blood samples
This study collects blood samples from people with and without bleeding risk to test a clot-dissolving drug (tPA) outside the body. It aims to improve minimally invasive surgery for brain hemorrhages.
LilleAges 18–65 - NCT07411313Recruiting
Ultrasound to predict low blood pressure in older adults having spinal anesthesia
This trial uses ultrasound to check your internal jugular vein, which may help predict if your blood pressure will drop during spinal anesthesia. It aims to find better ways to keep you safe during surgery.
Ankara, YENİMAHALLEAges 65 years+ - NCT07411716Recruiting
Children's liver disease registry in Canada
This study creates a registry to track children with specific genetic liver conditions that cause cholestasis (slow bile flow). Being in the registry helps researchers better understand these diseases and may help future patients.
Calgary, AlbertaAges Up to 18 years - NCT07412249Recruiting
Arm pressure cuff plus stent for blocked neck arteries
This trial tests if using a blood pressure cuff on the arm (to briefly restrict blood flow) before and after carotid stent placement can help reduce the risk of stroke. It is for people who have recently had stroke symptoms from a moderate to severe carotid artery blockage.
ShenyangAges 40 years+ - NCT07413159Recruiting
Check, monitor, control hypertension study
This 24-month trial tests whether combining pharmacist counseling with community health worker support helps African Americans aged 55+ better control their high blood pressure. You will receive extra guidance to manage your blood pressure at home.
Houston, TexasAges 55 years+ - NCT07413198Recruiting
Combined home and clinic exercise coaching for heart failure
This trial tests a program that combines home-based and clinic-based exercise coaching to help people with heart failure get more active. It aims to improve health and quality of life.
Winston-Salem, North CarolinaAges 55 years+ - NCT07413809RecruitingPhase 3
Preventing nausea after stem cell transplant: olanzapine vs dexamethasone
This trial compares two anti-nausea drug regimens (one with olanzapine, one with dexamethasone) to prevent delayed nausea and vomiting after a stem cell transplant for multiple myeloma. It aims to find which is better at controlling these side effects.
Ningbo, ZhejiangAges 18–65 - NCT07414121Recruiting
Vascular closure vs manual compression after AF ablation
This study compares two methods to close the blood vessel after a catheter ablation for atrial fibrillation (AF). It may help reduce bleeding or other problems at the access site.
HamburgAges 18–95 - NCT07414251Recruiting
Preparing children for heart procedures
This study looks at how children prepare for heart surgery or a heart catheterization. It will ask families to fill out questionnaires to help improve preoperative care.
Berlin, State of BerlinAges Up to 18 years - NCT07414342Recruiting
Study of RENATUS® valve for severe aortic stenosis
This study tests a new device called the RENATUS® Transcatheter Aortic Valve System for people with severe aortic stenosis. It is designed to replace the narrowed valve without open-heart surgery, and aims to see if it is safe and effective for patients with various surgical risk levels.
BeijingAges 60–100 - NCT07414446Recruiting
Detecting lung blood flow issues with a new ultrasound device
This trial uses a non-invasive ultrasound device to detect abnormal blood flow connections in the lungs, which are common in people with hereditary hemorrhagic telangiectasia (HHT) or a type of stroke called cryptogenic stroke. The goal is to see if the device can find these issues safely and easily without needing an invasive procedure.
Nieuwegein, UtrechtAges 18 years+ - NCT07414511Recruiting
Hemophilia A research study for pregnant families
This study follows pregnant people who carry a severe hemophilia A gene and their babies after birth. It looks at how hemophilia A is passed down and how it affects families, with the goal of improving understanding and care.
Seattle, WashingtonAges Any age - NCT07414732Recruiting
Testing a new approach to help stroke survivors take blood pressure pills
This trial tests a simple program to help people who have had a stroke stick with their blood pressure medication. It uses text messages and a medication organizer to make it easier to remember pills and keep blood pressure under control.
Boston, MassachusettsAges 18–99 - NCT07415447Recruiting
Aorta repair study: heart and vessel changes after stent procedure
This study looks at how the heart changes after a minimally invasive procedure to fix an aortic aneurysm. It uses imaging to track heart function and structure over time.
LisbonAges 18 years+ - NCT07415655RecruitingPhase 2
Albumin for stroke in the front of the brain
This trial tests whether giving albumin (a protein naturally in your blood) can help protect your brain after an ischemic stroke in the front part of your brain. You need to be planning a procedure to open the blocked vessel.
Hradec Králové, Czech RepublicAges 18 years+ - NCT07416279Recruiting
Can tiny bubbles replace catheters for heart pressure checks?
This trial tests if tiny ultrasound contrast bubbles can measure heart pressure, possibly replacing the need for catheter tubes. If you're already getting a heart catheterization, you may be able to join.
LondonAges 21–81 - NCT07417410Recruiting
Diabetes eye disease risk study
This study looks back at medical records of people with type 2 diabetes to understand how diabetic eye disease (retinopathy) progresses and when treatment is needed. It may help doctors better predict risks and guide future care.
Portugal, Coimbra DistrictAges 35–90 - NCT07418099Recruiting
Study on a blood test for prolonged clotting time
This study looks at a special blood test (clot waveform analysis) to see if it can help doctors better understand why some people have a prolonged clotting time. This might help them find the cause more quickly and accurately.
Leganés, MadridAges Any age - NCT07419087Recruiting
French trunk impairment scale adaptation and validation study
This study aims to adapt and validate a French version of the Trunk Impairment Scale, a tool that measures how well stroke survivors can control their trunk (core body) movements. Participating will help researchers improve stroke recovery assessments.
Ploemeur, Please Choose...Ages 18–85 - NCT07419360Recruiting
Draining fluid from lungs in heart failure
This study tests whether draining fluid from around the lungs can help people with heart failure who are in the hospital. It looks at how this procedure affects breathing and recovery.
Albany, New YorkAges 18 years+ - NCT07419997Recruiting
Observational study on clot-busting drugs beyond the usual window
This study looks at patients who received a clot-busting drug (intravenous thrombolysis) for their stroke 4.5 to 24 hours after symptoms started. It aims to see how well this works and what happens to them, using data that has already been collected.
BeijingAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,066 recruiting cardiology studies from the U.S. registry right now, out of 15,554 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.