Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,066 recruiting studies in this area right now.
By phase
- Not applicable8,037
- Phase 2488
- Phase 4482
- Phase 3452
- Phase 1360
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke856
- Heart Failure566
- Hypertension403
- Cardiovascular Diseases390
- Coronary Artery Disease375
- Multiple Myeloma329
- Atrial Fibrillation273
- Ischemic Stroke199
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension104
- Myocardial Infarction98
- Congenital Heart Disease87
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome83
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital54
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California467
- Alabama198
- Massachusetts181
- Arizona176
- New York166
- Florida145
- Illinois120
- Maryland120
- Texas120
- Minnesota119
Recruiting studies10,063 total
- NCT07476859RecruitingPhase 4
Iron for heart attack recovery in older adults
This study tests whether giving iron through a vein can improve quality of life in older adults who recently had a heart attack or unstable angina and also have low iron levels. If you qualify, you would receive either iron or a placebo (inactive substance) to see if iron helps you feel better and recover faster.
El Palmar, MurciaAges 65 years+ - NCT07477197Recruiting
Heart Institute Biobank for Adult Congenital Heart Disease
This study collects blood and tissue samples and health information from adults with or at risk for congenital heart disease or related heart conditions. It aims to help researchers better understand these conditions and improve future treatments.
Cincinnati, OhioAges 16 years+ - NCT07477587RecruitingPhase 1
Comparing two myeloma treatments for new patients
This trial tests a new drug combination (HLX15-SC) against an approved treatment (DARZALEX FASPRO) along with lenalidomide and dexamethasone for people newly diagnosed with multiple myeloma who cannot have a stem cell transplant.
Springdale, ArkansasAges 18 years+ - NCT07477912RecruitingPhase 1/Phase 2
BCMA-targeting CAR-T for relapsed/refractory multiple myeloma
This trial tests a new kind of immunotherapy called CAR-T that targets BCMA on myeloma cells. It is for people whose multiple myeloma has come back after or not responded to at least two previous treatments.
MinskAges 18 years+ - NCT07478003RecruitingPhase 3
Early steroid for severe heart attacks before reaching the hospital
This study tests whether giving a high dose of a steroid medication (glucocorticoid) early, before reaching the hospital, can help people having a severe type of heart attack called STEMI. If you are having this specific heart attack and meet the criteria, receiving this medication might improve your recovery.
AalborgAges 18 years+ - NCT07478354Recruiting
Heart Tissue and Blood Study for Pediatric Heart Disease
This study collects samples (blood, tissue, and other specimens) from people of all ages who have or are at risk for pediatric heart disease. The goal is to build a research bank to better understand these conditions and develop new treatments.
Cincinnati, OhioAges Any age - NCT07479056Recruiting
Fexuprazan to prevent stomach bleeding in heart patients on two blood thinners
This trial tests whether fexuprazan can prevent upper gastrointestinal bleeding in people at high risk who need two antiplatelet drugs for at least 6 months after a heart stent. If you are on dual antiplatelet therapy after a stent and have risk factors like older age, low weight, or history of ulcers, this study may help protect your stomach.
Seoul, Eunpyeong-guAges 20 years+ - NCT07479147Recruiting
Stroke prevention in elderly by PFO closure vs blood thinners
This trial compares two treatments for preventing another stroke in older adults who have a PFO (a small hole in the heart). It tests whether closing the hole with a device works better than using blood-thinning medication.
TaichungAges 18–90 - NCT07479186Recruiting
How aortic disease affects quality of life and work
This study looks at how having an aortic disease (a problem with the main artery from your heart) impacts your daily life and ability to work. It aims to help doctors better understand and support patients like you.
Roma, RMAges 18–70 - NCT07479433Recruiting
New approach to plan stent placement using CT scans
This study tests if using a special CT scan analysis can help doctors plan where to place stents for blocked arteries. It might make the procedure safer and more effective for people who are scheduled for a planned stent procedure.
Marietta, GeorgiaAges 18 years+ - NCT07480265Recruiting
Homocysteine and early heart function in new high blood pressure
This study looks at a substance in your blood called homocysteine and how it affects the early filling of your heart's main pumping chamber. It may help doctors understand heart risks in people newly diagnosed with high blood pressure.
Konya, MeramAges 18 years+ - NCT07480512Recruiting
A study on causes and outcomes of coronary artery disease
This study follows people with different types of coronary artery disease over time to understand what causes their condition to get better or worse, and how well they do. The goal is to improve future treatment and care.
Guangzhou, GuangdongAges 18 years+ - NCT07480915Recruiting
Heart failure risk after bypass surgery
This study looks at how to predict major heart problems in people with heart failure who are scheduled for bypass surgery (CABG). It aims to improve risk assessment before the procedure.
Tomsk, Tomsk OblastAges Any age - NCT07481396Recruiting
Studying brain injury after cardiac arrest through spinal fluid
This trial is looking at the spinal fluid of people who survived a cardiac arrest outside the hospital and are being treated for brain injury. The goal is to learn more about brain damage and find new ways to help patients recover.
Daejeon, Jung-guAges 18 years+ - NCT07481851Recruiting
Can skin sensor predict blood pressure drop during spinal anesthesia?
This study tests whether a simple skin sensor can predict a dangerous drop in blood pressure during spinal anesthesia for older adults having urologic cancer surgery. If it works, doctors could take steps to prevent dizziness or fainting.
Ankara, YenimahalleAges 65 years+ - NCT07482020RecruitingPhase 2
SGLT2 inhibitor for atrial fibrillation, high blood pressure, and high blood sugar
This study tests whether a medication called an SGLT2 inhibitor (a type of diabetes drug) can improve the function of the upper left heart chamber in people who have paroxysmal atrial fibrillation, high blood pressure, and abnormal blood sugar levels. If you qualify, the trial may help your heart work better and reduce your risk of stroke.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07482124Recruiting
Registry study for patients with subarachnoid hemorrhage
This study collects information on people who have had a subarachnoid hemorrhage (a type of brain bleed) from certain causes. It helps doctors better understand the condition and improve care.
Nijmegen, GelderlandAges Any age - NCT07482137Recruiting
Electroacupuncture for diabetic foot wounds
This trial tests whether electroacupuncture at a specific point (ST-36) can help heal diabetic foot ulcers. It may be an option for people with diabetic foot sores that have not healed well.
Nanjing, JiangsuAges 18–75 - NCT07482228Recruiting
Long-term outcomes after retinal artery occlusion
This study looks at the long-term health results of people who have a retinal artery occlusion (a blockage in the blood vessels of the eye). It aims to understand what happens over time, which can help guide treatment and care.
Gwangju, GwangjuAges Any age - NCT07482462Recruiting
Blood pressure and heart rate study in healthy and hypertensive adults
This trial looks at how blood pressure and heart rate change when standing up or exercising in healthy people and in older adults with high blood pressure. It aims to understand how the body's automatic (autonomic) nervous system controls these functions.
LjubljanaAges 18 years+ - NCT07482501Recruiting
Magnetic brain stimulation for heart health after stroke
This study uses repetitive transcranial magnetic stimulation (a non-invasive brain treatment using magnetic pulses) to improve heart rate control in people who have had a stroke. It may help your body better manage stress and blood pressure.
AfyonkarahisarAges 35–80 - NCT07482579Recruiting
Stroke Recovery Prediction Using a Digital Twin
This study uses digital twin technology to predict how well people will recover after a stroke. It looks at your walking ability and other factors to create a personalized recovery plan.
Gyeonggi-do, Gyeonggi-doAges 20 years+ - NCT07483177RecruitingPhase 1/Phase 2
Heart study for enlarged aorta
This trial tests a treatment to help people with a mildly enlarged ascending aorta. It aims to slow down growth and prevent future heart problems.
Rochester, MinnesotaAges 18 years+ - NCT07483151Recruiting
Heart Surgery and Thinking Changes Study
This study looks at how changes in blood flow (called venous congestion) after heart surgery might affect thinking and memory. It aims to find out if there is a link between how blood returns to the heart and brain function after surgery.
Yangzhou, JiangsuAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,066 recruiting cardiology studies from the U.S. registry right now, out of 15,554 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.