Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,066 recruiting studies in this area right now.
By phase
- Not applicable8,037
- Phase 2488
- Phase 4482
- Phase 3452
- Phase 1360
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke856
- Heart Failure566
- Hypertension403
- Cardiovascular Diseases390
- Coronary Artery Disease375
- Multiple Myeloma329
- Atrial Fibrillation273
- Ischemic Stroke199
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension104
- Myocardial Infarction98
- Congenital Heart Disease87
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome83
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital54
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California467
- Alabama198
- Massachusetts181
- Arizona176
- New York166
- Florida145
- Illinois120
- Maryland120
- Texas120
- Minnesota119
Recruiting studies10,063 total
- NCT07483203Recruiting
Lung blood vessel health in people getting heart valve procedures
This study looks at how lung blood vessels work in people who are getting their heart valve fixed or replaced. It may help doctors understand and manage related lung issues.
Rochester, MinnesotaAges 18 years+ - NCT07483502Recruiting
Pre-surgery gut health supplement study for heart patients
This trial tests whether taking a gut health supplement (WellBiome) for six weeks before heart surgery can improve recovery and save the NHS money. It compares the supplement to a placebo (a pill with no active medicine).
Hull, East Riding Of YorkshireAges 50–80 - NCT07484009Recruiting
ReDS-guided fluid removal for heart failure patients
This trial tests if using a wearable monitor (ReDS) to guide fluid removal helps people hospitalized for heart failure. The goal is to find the right amount of fluid to remove so patients feel better and stay out of the hospital.
Madrid, MadridAges 18 years+ - NCT07484854Recruiting
FES-assisted arm bike training for recent stroke recovery
This study tests whether adding Functional Electrical Stimulation (FES) to arm bike exercises can help improve arm movement in people who had a stroke within the last six months. It is designed for those with weakness on one side of the body.
Ankara, ÇankayaAges 18–85 - NCT07485088Recruiting
Video to reduce anxiety before heart stent procedure
This trial tests if watching a video before a planned heart stent procedure can lower anxiety. If you are scheduled for this procedure and speak English, you may be eligible.
SingaporeAges 21 years+ - NCT07485283RecruitingPhase 4
Shingles vaccine for preventing heart problems and dementia
This trial tests whether a shingles vaccine can help prevent heart attacks, strokes, and dementia in older adults. If you are 65 or older and haven't had the shingles vaccine before, you may be able to join.
HellerupAges 65 years+ - NCT07485738Recruiting
Blood flow during bypass surgery and graft recovery
This study looks at how blood flow readings during coronary artery bypass surgery relate to whether the new grafts stay open and how well patients recover. It aims to help improve long-term results for people needing bypass surgery.
New York, New YorkAges 18 years+ - NCT07486271Recruiting
AI in Aortic Regurgitation trial
This trial uses artificial intelligence to help measure aortic regurgitation, a heart valve problem. It aims to improve how doctors assess and treat this condition.
Hong Kong, New TerritoriesAges 18 years+ - NCT07674173Recruiting
Registry study of Minos stent-graft for abdominal aortic aneurysm
This study tracks the long-term safety and effectiveness of the Minos stent-graft system in treating abdominal aortic aneurysms. It collects data from patients across Europe and Asia to see how well the device works over five years.
Lanzhou, GansuAges 18 years+ - NCT06451757RecruitingPhase 3
A trial of sonlicromanol for mitochondrial disease
This trial tests a new medicine, sonlicromanol, for people with a specific type of mitochondrial disease (caused by the m.3243A>G mutation) who also have chronic fatigue and muscle weakness. The goal is to see if it helps improve symptoms and daily function.
Boston, MassachusettsAges 18 years+ - NCT06202820Recruiting
Heart health monitoring for men on hormone therapy
This study checks how men starting hormone therapy (ADT) for prostate cancer are doing with their heart health. It offers follow-up visits at the cancer center to track blood pressure and lab results, with the goal of catching any heart-related issues early.
Boston, MassachusettsAges 18 years+ - NCT05111015Recruiting
Ablation tracking study for people with atrial fibrillation
This study tracks results after a heart ablation procedure used to treat atrial fibrillation (an irregular heart rhythm). You may be asked to help by consenting and following the study plan so the researchers can better understand what happens after ablations.
Huntsville, AlabamaAges 18 years+ - NCT05672836RecruitingPhase 4
Enavogliflozin after TAVR for heart narrowing with mild heart weakness
This trial tests enavogliflozin (a diabetes medication that may help the heart) in people who have had a TAVR procedure for severe aortic stenosis. It looks at whether the medicine can improve outcomes for people with symptoms and mildly reduced or preserved pumping function.
Bucheon-siAges 19 years+ - NCT07554235Recruiting
Acupuncture for better sleep in seniors with diabetes and high blood pressure
This trial tests if acupuncture given by village doctors can help older adults with both diabetes and high blood pressure sleep better. It aims to improve sleep quality without using sleep medications.
Taizhou, JiangsuAges 65 years+ - NCT07674498Recruiting
Immune health in older adults with advanced myeloma
This trial studies the immune system of adults 65 and older with multiple myeloma that has come back or not responded to treatment. It looks at how their immune fitness may affect their ability to receive newer therapies like CAR-T cells or bispecific antibodies.
Anderlecht, Brussels CapitalAges 65 years+ - NCT07672860RecruitingPhase 2
UDCA to protect kidneys during partial nephrectomy
This clinical trial is testing whether a medicine called ursodeoxycholic acid (UDCA) can help protect the kidneys during partial nephrectomy (removing only the tumor while keeping the healthy part of the kidney). It is for people with early-stage kidney tumors who will have temporary interruption of blood flow to the kidney during surgery.
Nanjing, JiangsuAges 18–75 - NCT07538388Recruiting
Comparing two ways to give norepinephrine during surgery to prevent low blood pressure
This trial compares two ways of giving a drug called norepinephrine to keep blood pressure stable during surgery. If you are 45 or older and having non-cardiac surgery, this study may help prevent low blood pressure and protect your kidneys.
BerlinAges 45 years+ - NCT06919315Recruiting
Cognitive strategy training for stroke or brain injury recovery
This trial tests a therapy called CO-OP that helps people with stroke or traumatic brain injury improve their daily activities by learning new thinking strategies. You may benefit if you have trouble with everyday tasks like dressing or cooking.
ViborgAges 18 years+ - NCT06617377Recruiting
Can MRI predict brain recovery after cardiac arrest?
This study uses brain scans (MRI) to try to predict whether people who are still unconscious after a cardiac arrest will recover. It is looking for adults who are in a coma and have not woken up after being taken off sedation medicines for at least three days.
ToulouseAges 18 years+ - NCT04462380Recruiting
AI study for patients after cardiac arrest
This trial uses artificial intelligence to analyze computerized reports from patients who have recovered from cardiac arrest. It aims to help doctors better understand and treat different causes of cardiac arrest.
NiceAges 18 years+ - NCT06989775Recruiting
BoxX-NoAF Trial: Preventing Stroke During Heart Surgery
This trial tests a device to close a small pouch in the heart during planned bypass surgery, to help prevent future strokes. It is for people who have never had an irregular heartbeat and are at higher stroke risk due to age and other factors.
Jonesboro, ArkansasAges 65 years+ - NCT07674329Recruiting
Virtual reality rehab for arm strength after stroke
This trial tests if using virtual reality (VR) exercises early after an ischemic stroke can help improve arm muscle strength, thinking skills, and mood. It is for people who have had a stroke within the last 10 days.
TaipeiAges 18–85 - NCT06241430Recruiting
CardioClip study: testing a new valve repair for leaky heart valve
This study tests a new clip procedure (CardioClip) to repair a leaky mitral valve in people with heart failure. It aims to see if the clip can improve symptoms and heart function.
New York, New YorkAges 18–90 - NCT03934905RecruitingPhase 1/Phase 2
Sulforaphane supplement to protect the heart during doxorubicin
This trial tests whether a nutritional supplement called sulforaphane (SFN) can help protect heart function in people with breast cancer who are receiving doxorubicin (a chemotherapy that can affect the heart). Participants take caplets and have heart and safety monitoring to see if the supplement reduces heart-related side effects.
Lubbock, TexasAges 18–89
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,066 recruiting cardiology studies from the U.S. registry right now, out of 15,554 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.