Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,073 recruiting studies in this area right now.
By phase
- Not applicable8,041
- Phase 2490
- Phase 4483
- Phase 3452
- Phase 1359
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke855
- Heart Failure565
- Hypertension403
- Cardiovascular Diseases389
- Coronary Artery Disease375
- Multiple Myeloma330
- Atrial Fibrillation273
- Ischemic Stroke200
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension104
- Myocardial Infarction98
- Congenital Heart Disease87
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital54
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California467
- Alabama198
- Massachusetts181
- Arizona176
- New York166
- Florida146
- Maryland120
- Texas120
- Illinois119
- Minnesota119
Recruiting studies10,070 total
- NCT06641843Enrolling by invitation
Heart stress test using MRI for children with heart disease
This study uses magnetic resonance imaging (MRI) to look at blood flow to the heart muscle during stress in children with certain heart conditions. It may help doctors better understand how the heart is working.
Chengdu, SichuanAges Up to 18 years - NCT06641817Enrolling by invitation
Heart imaging study for Kawasaki disease
This study uses heart imaging to better understand Kawasaki disease. It may help doctors assess heart health in affected children and teenagers.
Chengdu, SichuanAges Up to 18 years - NCT06634004Enrolling by invitation
Using biomarkers to improve surgery outcomes in Moyamoya
This study at Vanderbilt tests whether certain biomarkers (signs in your blood or brain scans) can help tailor care for people with Moyamoya, a condition where blood flow to the brain is reduced. Participants will have brain scans and complete study procedures before and after surgery to improve blood flow.
Baltimore, MarylandAges 18–69 - NCT06629701Enrolling by invitation
Support mesh for vein grafts in heart bypass
This study tests a new external support mesh wrapped around vein grafts used in heart bypass surgery to see if it helps them stay open longer. The trial is for people having planned bypass surgery for multiple blocked arteries with no recent blood clots or current use of certain blood thinners.
Pilsen, Czech RepublicAges 20–90 - NCT06625294Enrolling by invitation
Hand therapy after stroke: comparing two approaches
This study compares two types of hand therapy for stroke survivors: one that restricts your good hand to force use of the affected hand, and another that practices tasks with both hands together. The goal is to see which works better for improving hand function.
IslamabadAges 40–60 - NCT06622473Enrolling by invitation
Testing the virtual eggs test for stroke recovery
This trial tests a virtual task called the 'Eggs Test' to see if it can help measure hand and arm function after a stroke. It may help people who are at least 2 weeks past their first stroke and can move their arm enough to do the task.
Florence, FlorenceAges 18–85 - NCT06613282Enrolling by invitation
Brain stimulation safety study in healthy volunteers
This early-phase trial tests a combination of two non-invasive brain stimulation techniques (LI-TMS and AVS) in healthy people to see if they are safe and well-tolerated. It is a first step before studying these treatments for stroke recovery.
Novosibirsk, Novosibirsk OblastAges 35–65 - NCT06605833Enrolling by invitation
Heart health after immunotherapy for melanoma
This study looks at heart health in people who have finished immunotherapy for melanoma. It uses MRI scans to check for any heart problems that may have developed after treatment.
LondonAges 18 years+ - NCT06597188Enrolling by invitation
TAVR vs. Surgery for severe bicuspid aortic valve stenosis
This trial compares a less invasive valve replacement (TAVR) with traditional open-heart surgery for people with a specific type of severe aortic valve narrowing (bicuspid valve). It aims to see which approach works better for those at intermediate or low surgical risk.
Chengdu, SichuanAges 18–75 - NCT06595615Enrolling by invitation
Heart health app data collection study
This trial gathers health data from a smartphone app to learn more about heart failure in people with a specific type of implanted heart device. The information will help doctors better understand how to treat and manage heart failure.
Huntsville, AlabamaAges 18 years+ - NCT06585917Enrolling by invitation
Comparing two sheath sizes for wrist artery heart procedures
This trial compares two sizes of small tubes (called sheaths) used during a heart procedure to open blocked arteries. The procedure is done through a tiny artery in your wrist, and the goal is to see if a smaller tube works just as well with fewer side effects.
Beijing, Beijing MunicipalityAges 18–80 - NCT06585215Enrolling by invitation
Standardizing stent grafts for aortic aneurysms
This trial aims to create a standard method for doctors making custom stent grafts during surgery. It focuses on safer, more consistent repair of abdominal aortic aneurysms.
Lugano, Canton TicinoAges Any age - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT06578117Enrolling by invitation
Visual training for stroke-related vision loss
This study tests whether a computer-based visual training program can help people who have lost vision after a stroke to their brain's visual center. You must have been in a prior study with the same team.
Rochester, New YorkAges 21–75 - NCT06577714Enrolling by invitation
Heart ablation guided by advanced imaging
This study tests a new imaging technique to help guide heart ablation procedures for certain heart rhythm problems. It may help doctors see exactly where to treat.
New York, New YorkAges 18 years+ - NCT06576544Enrolling by invitation
Wearables to Track Postpartum Blood Pressure
This study uses wearable devices to track your blood pressure after childbirth. The goal is to learn when blood pressure problems occur and help create better monitoring guidelines so you and future parents can get the right care at the right time.
La Jolla, CaliforniaAges 18–50 - NCT06571175Enrolling by invitation
Measuring heart scarring in aortic stenosis patients
This study uses imaging to measure heart scarring in people with aortic stenosis, a condition where the heart valve is narrowed. It aims to better understand how scarring affects long-term outcomes.
Trondheim, TrøndelagAges 18–90 - NCT06551727Enrolling by invitation
Stroke progression treatment: blood pressure and antiplatelet therapy
This trial tests a combination of blood pressure control and antiplatelet therapy for people whose stroke symptoms are getting worse. It is looking for those without a large brain artery clot or heart-related cause.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06544902Enrolling by invitation
Virtual Reality for Stress and Blood Pressure in Black Women
This study tests if a virtual reality program can help Black women lower stress and blood pressure. You would use VR headsets over several weeks to learn relaxation and resilience skills.
Miami, FloridaAges 21 years+ - NCT06542939Enrolling by invitation
Telehealth for diabetes and hypertension in South Asians
This study tests a telehealth program to help South Asian adults manage both diabetes and high blood pressure. If you have these conditions and your blood pressure is not well controlled, this program could help you improve your health from home.
New York, New YorkAges 21 years+ - NCT06542575Enrolling by invitation
Home heart rehab with app after stent
This trial tests a home-based program that uses a smartphone app (digital therapy) to help people with high-risk heart conditions after a stent procedure. The goal is to improve recovery through exercise and lifestyle support, all from home.
Chengdu, SichuanAges 18–75 - NCT06542432Enrolling by invitation
Genetic risk test for heart disease prevention
This trial uses a polygenic risk score to see if knowing your genetic risk for coronary artery disease can help prevent a first heart attack. If you have an intermediate 10-year risk and no prior heart events, you may be eligible.
Rochester, MinnesotaAges 40–70 - NCT06541275Enrolling by invitation
Shrinking large brain aneurysms after treatment
This trial looks at how well large or giant brain aneurysms shrink over time after a minimally invasive procedure called endovascular intervention. It may help doctors understand which treatments lead to better long-term results.
AstanaAges 18 years+ - NCT06534281Enrolling by invitationEarly Phase 1
BAO-G technique for TAAA aneurysm repair
This trial is testing a new technique (BAO-G) for repairing a thoracoabdominal aortic aneurysm (TAAA) using a stent placed through a blood vessel in the leg. It is for people with a large aneurysm or one causing symptoms, who have not had prior aortic repair.
BeijingAges 18–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,073 recruiting cardiology studies from the U.S. registry right now, out of 15,588 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.