Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,073 recruiting studies in this area right now.
By phase
- Not applicable8,041
- Phase 2490
- Phase 4483
- Phase 3452
- Phase 1359
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke855
- Heart Failure565
- Hypertension403
- Cardiovascular Diseases389
- Coronary Artery Disease375
- Multiple Myeloma330
- Atrial Fibrillation273
- Ischemic Stroke200
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension104
- Myocardial Infarction98
- Congenital Heart Disease87
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital54
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California467
- Alabama198
- Massachusetts181
- Arizona176
- New York166
- Florida146
- Maryland120
- Texas120
- Illinois119
- Minnesota119
Recruiting studies10,070 total
- NCT06533007Enrolling by invitation
How PDE3B affects metabolism in healthy adults
This study looks at how a protein called PDE3B affects your body's metabolism (how it uses energy). It may help researchers understand weight and insulin resistance better, which could lead to new treatments.
CambridgeAges 21–75 - NCT06518681Enrolling by invitation
Testing a new polymer heart valve for aortic disease
This trial tests a new type of artificial heart valve made of polymer (a special plastic-like material) for people with severe aortic valve disease. It aims to see if the valve is safe and works well, giving you an option for a replacement valve that might last longer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06512922Enrolling by invitation
Cognitive training for older adults with high blood pressure
This trial tests whether a special computer-based brain training program can help older adults with high blood pressure think more clearly. It is done in your local community and aims to find a way to keep your mind sharp as you age.
Beijing, ShijingshanAges 60 years+ - NCT06511700Enrolling by invitation
Nurse-led eye injections: a new care approach
This trial tests whether specially trained nurses can safely give eye injections instead of doctors. It may make treatment quicker and easier for people who need regular injections for eye conditions.
Sabadell, BarcelonaAges 18 years+ - NCT06510634Enrolling by invitation
Stroke treatment after 24 hours for vertebrobasilar blockage
This trial tests a method to triage people who had a stroke in the back part of the brain (vertebrobasilar artery) more than 24 hours ago. The goal is to find the best way to decide which patients may still benefit from treatment.
Tianjin, Tianjin MunicipalityAges 18–90 - NCT06509776Enrolling by invitation
Bone growth and hormone health in young adults
This study looks at how bones mature and how hormones change as you become a young adult. If you were born in Denmark in 2006 or 2007 and are 18, you may be invited to help researchers understand these changes.
AalborgAges 18–19 - NCT06507449Enrolling by invitation
Treating Heavily Calcified Heart Blockages to Improve Microcirculation
This study is testing a technique to treat heavily calcified (hard) blockages in heart arteries. The goal is to see if a special way of preparing the blockage before placing a stent helps improve blood flow to the tiny blood vessels in the heart muscle.
KatowiceAges 18 years+ - NCT06483165Enrolling by invitation
F.A.S.T. and BE FAST stroke signs study
This study asks the public to share how well they know the warning signs of stroke (using the F.A.S.T. or BE FAST mnemonic). It may help improve stroke awareness and save lives.
Dallas, TexasAges 19 years+ - NCT06482424Enrolling by invitation
Aromatherapy for sleep and anxiety in high blood pressure
This study tests whether lavender aromatherapy can help people with high blood pressure sleep better, feel less anxious, and improve their blood pressure and heart rate. You would inhale a lavender scent nightly and measure your blood pressure at home.
Merkez, Niğde ProvinceAges 1.5 years–5.4 years - NCT06476431Enrolling by invitation
Smartglasses walking training for stroke recovery
This trial tests whether walking while wearing smartglasses that show simple mental tasks can help stroke survivors improve their step and thinking coordination. It's for people who can walk on their own and have weakness on one side from a stroke.
Uijeongbu-si, Gyeonggi-doAges 20–80 - NCT06471309Enrolling by invitation
Theta burst TMS for swallowing problems after stroke
This trial tests a type of brain stimulation called theta burst transcranial magnetic stimulation (TMS) to see if it can help people who have trouble swallowing after a stroke. It is designed for people who had their first stroke within the last 2 weeks to 6 months and are right-handed.
Zhengzhou, HenanAges 18–80 - NCT06464835Enrolling by invitation
Brain stimulation and swallowing therapy for post-stroke swallowing problems
This trial tests whether combining two types of brain stimulation (iTBS and NMES) can improve swallowing problems after a stroke. If you have had trouble swallowing for at least two weeks but no longer than six months after your stroke, you may be able to join.
Zhengzhou, HenanAges 18–80 - NCT06464315Enrolling by invitation
VT Ablation Guided by Scar Tissue Only
This trial tests a new approach to treating a dangerous heart rhythm called ventricular tachycardia (VT) in people with scarred heart muscle. The goal is to use only the scarred area to guide the ablation procedure, which may make it safer and more effective.
San Diego, CaliforniaAges 18–90 - NCT06461468Enrolling by invitation
AI study for hypertrophic cardiomyopathy using heart tests
This study uses artificial intelligence to analyze ECGs and echoes from people with hypertrophic cardiomyopathy (HCM) to improve how the disease is detected and managed. If you have HCM with a thickened heart wall and available heart tests, you may help train the AI.
Fairhope, AlabamaAges 18 years+ - NCT06460402Enrolling by invitation
Ice packs and warm baths after hemorrhoid surgery
This trial tests whether using ice packs and warm baths after hemorrhoid surgery helps wounds heal faster and reduces pain more than standard care. If you are having surgery to remove hemorrhoids, this study may offer a simple, gentle way to help you recover.
Kaohsiung CityAges 18–80 - NCT06452823Enrolling by invitation
Catheter ablation for atrial fibrillation with stable thyroid
This trial tests whether doing a heart procedure (catheter ablation) is safe and works well for people with atrial fibrillation whose thyroid hormone levels are stable. It aims to help people with both conditions get the best treatment.
Jiaxing, ZhejiangAges 45–75 - NCT06452173Enrolling by invitation
Risk prediction for stroke in carotid artery narrowing
This study uses MRI scans to build a risk prediction model for stroke and other cerebrovascular events in people with carotid artery stenosis (narrowing of the neck arteries). By participating, you help doctors better understand who is at highest risk, which may lead to more personalized treatment.
Beijing, Beijing MunicipalityAges Any age - NCT06451458Enrolling by invitation
ECHO diabetes and chronic conditions training for care teams
This trial tests a program (ECHO) to help healthcare teams at busy clinics better support patients with diabetes and other ongoing health conditions. It focuses on training staff, not on giving you a new treatment.
Santa Fe, New MexicoAges 18–89 - NCT06444425Enrolling by invitation
AI test for heart function using ultrasound
This trial uses artificial intelligence to analyze heart ultrasound images. It aims to see if AI can detect heart function better than standard methods. You may be eligible if you are a cardiology patient having an ultrasound and can return for extra blood pressure checks.
Yiwu, ZhejiangAges 18 years+ - NCT06439667Enrolling by invitation
Home Exercise Program for Diabetic Foot Ulcers
This trial tests a home exercise program delivered by video to help heal diabetic foot ulcers. It's designed for people who can walk on their own and have a relatively new ulcer.
Los Angeles, CaliforniaAges 18 years+ - NCT06434935Enrolling by invitationEarly Phase 1
Trial of a new bypass graft for heart surgery
This trial tests a new artificial blood vessel for heart bypass surgery. If you need a bypass and meet the health requirements, you may be able to receive this experimental graft.
AsunciónAges 45–75 - NCT06434168Enrolling by invitation
Yoga for brain health in heart failure
This study tests whether yoga can help improve memory and thinking for people with heart failure who also have mild memory problems. It aims to see if a gentle yoga program can support both heart and brain health.
Auburn, AlabamaAges 55–70 - NCT06433622Enrolling by invitation
Platelet transfusion for severe brain injury on blood thinners
This trial tests whether giving a platelet transfusion to patients with severe traumatic brain injury who are on antiplatelet medication can improve how well their blood clots. You may qualify if you have a serious brain bleed and are taking a medication like aspirin or clopidogrel.
Lancaster, PennsylvaniaAges 18 years+ - NCT06432452Enrolling by invitationPhase 2/Phase 3
Testing a new drug for coronary artery spasm
This trial tests a drug that blocks certain receptors to see if it reduces chest pain caused by coronary artery spasm. If you have frequent angina despite current treatments, this study may offer a new option.
Eindhoven, North BrabantAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,073 recruiting cardiology studies from the U.S. registry right now, out of 15,588 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.