Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,973 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2481
- Phase 4480
- Phase 3447
- Phase 1360
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke843
- Heart Failure565
- Hypertension399
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma333
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke138
- Myocardial Infarction101
- Pulmonary Hypertension100
- Stroke, Ischemic86
- Congenital Heart Disease85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California461
- Alabama197
- Massachusetts183
- Arizona173
- New York161
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,970 total
- NCT07626060Recruiting
AI Tools for Chest Pain Risk Assessment
This study tests whether artificial intelligence (AI) programs can accurately calculate a chest pain risk score to help doctors decide who needs urgent heart tests. You'll be monitored for 30 days to see if the AI's predictions were correct.
Istanbul, IstanbulAges 18 years+ - NCT03469440Recruiting
Targeted oxygen monitoring during children’s heart surgery
This trial tests whether a goal-focused monitoring approach can help optimize oxygen levels in the blood during children’s heart surgery using a heart-lung machine. It may help clinicians adjust care more precisely during surgery.
São PauloAges Up to 14 years - NCT07079735RecruitingPhase 2/Phase 3
Preventing CMV after heart transplant
This trial compares two antiviral drugs, valganciclovir and letermovir, to see which works better at preventing CMV infection after a heart transplant. If you've had a heart transplant and haven't started preventive treatment yet, this study may be for you.
New York, New YorkAges 18–99 - NCT06249568Recruiting
Testing fluid response during heart bypass surgery
This study tests a method to see if your body needs more fluids during heart bypass surgery. After the surgeon opens your chest, they will use a special breathing maneuver to check how well your heart responds to extra fluid, which may help guide your care.
AnkaraAges 18–80 - NCT02318342Recruiting
Testing blood-thinner treatment for clogged aortic bioprosthetic valves
This study checks whether a blood-thinning medicine can treat problems with a bioprosthetic (man-made tissue) aortic valve. It focuses on valve “clots” that can happen after either a catheter-based or surgery-based valve replacement.
Los Angeles, CaliforniaAges 18 years+ - NCT07075926Recruiting
Heart ultrasound to predict breathing tube removal success in ICU
This study uses a heart ultrasound to see if it can help doctors predict when patients in the ICU are ready to have their breathing tube removed. It may help avoid failed extubations and reduce complications.
Istanbul, IstanbulAges 18 years+ - NCT06503965Recruiting
Tracking aortic valve implant outcomes in Tunisia
This trial collects information from people in Tunisia who have had a TAVI procedure (a less invasive way to replace a heart valve). By joining, you help doctors learn how well the procedure works over time.
TunisAges 18–85 - NCT06802926RecruitingPhase 4
Colchicine to prevent graft failure after bypass surgery
This study tests whether a low dose of colchicine, an anti-inflammatory drug, can help prevent the graft (new blood vessel) from failing after heart bypass surgery. It's for people who just had a bypass and are still in the hospital.
ShanghaiAges 18 years+ - NCT06159608RecruitingEarly Phase 1
E-cigarette effects on blood vessels in young adults
This study looks at how e-cigarettes affect blood vessels in young adults. Researchers want to compare first-time vapers, experienced vapers, and non-vapers to see if there are differences between men and women.
Iowa City, IowaAges 18–24 - NCT06274411Recruiting
Backup ECMO for high-risk heart stenting
This trial studies a safe, backup ECMO machine for people with very weak hearts or complex blockages who need high-risk stenting. It helps keep your blood pumping if your heart struggles during the procedure.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06272734Recruiting
Reprieve system study for hospitalized heart failure
This study tests a device (Reprieve System) to remove extra fluid more safely in heart failure patients while they are hospitalized. It may be a good option if you have fluid buildup and are not too sick from other conditions.
TbilisiAges 18 years+ - NCT07608926Recruiting
Heart Health Management: Digital Tools vs. Traditional Care
This study compares a new way to manage heart disease risk factors using digital technology (like apps or remote monitoring) with the traditional doctor visit approach. It aims to see which method better helps people control high blood pressure, blood sugar, cholesterol, and weight over 2 years.
Cotignola, RavennaAges 40–75 - NCT06878885Recruiting
Heart health & trauma study for American Indian adults
This study looks at how trauma affects heart and metabolic health in American Indian adults living on or near the Blackfeet reservation.
Browning, MontanaAges 18–40 - NCT01777828Recruiting
Registry for patients with valve replacements via catheter
This is a registry that collects information from people who had an artificial aortic valve put in using a catheter-based approach. It may help doctors better understand outcomes and care for these specific valve replacements.
RennesAges Any age - NCT06261866Recruiting
Heart imaging for moderate blockages in stable heart disease
This trial tests whether combining two advanced imaging tests (FFR and OCT) can help doctors better decide treatment for moderate blockages in heart arteries. If you have stable chest pain or a positive stress test and a moderate narrowing, this study may help guide your care.
WarsawAges 18 years+ - NCT07642765Recruiting
Frailty Score and Blood Pressure Changes During Surgery
This study looks at a simple scoring system (EASIX) that predicts whether older or frail patients will experience dangerous blood pressure drops when anesthesia is given before surgery. Understanding this risk might help doctors better protect vulnerable patients during their operations.
KonyaAges 18 years+ - NCT07285031Recruiting
Histamines and blood vessel health study
This study looks at how histamines affect blood pressure and heart function in healthy young adults. You will visit the lab three times to help researchers understand these effects.
Kelowna, British ColumbiaAges 19–39 - NCT03667326RecruitingPhase 2
Low-dose aspirin after severe preeclampsia
This Phase 2 study tests whether starting low-dose aspirin after delivery can help people who had severe preeclampsia. The goal is to see if this treatment is safe and beneficial in the weeks after birth.
New York, New YorkAges 18 years+ - NCT06282042Recruiting
Early Fix of Leaky Mitral Valve After Heart Attack
This trial tests an early, minimally invasive procedure to fix a leaky mitral valve using a catheter (a thin tube) after a heart attack. The goal is to see if fixing the valve early can help patients recover better and avoid more serious heart problems.
Afula, AfulaAges 18–99 - NCT02829190RecruitingPhase 3
MRI test to map blood flow in neck arteries
This study checks whether a special MRI scan can measure blood flow in certain neck artery branches. It compares results in different groups (healthy people and people with past neck radiation or procedures) to see how well the scan works.
Amiens, PicardieAges 18–70 - NCT05604131RecruitingPhase 2
Cardiac MRI-guided iron-chelator treatment after a heart attack
This Phase 2 trial tests whether giving deferiprone (an “iron-chelator,” meaning it helps remove excess iron) guided by cardiac MRI can improve outcomes after an acute anterior heart attack. It aims to study safety and benefit for people who can undergo MRI with contrast and meet specific heart, kidney, liver, and blood criteria.
Indianapolis, IndianaAges 18–79 - NCT05311072Recruiting
Update a CTEPH patient database in China
This study helps doctors update and improve how they understand chronic thromboembolic pulmonary hypertension (CTEPH) in patients in China. It likely involves sharing your medical information (not a new drug) and confirming your diagnosis details to support future research.
BeijingAges 14 years+ - NCT05441839Recruiting
Heart failure with preserved pumping function study in the UK
This trial studies people who have heart failure symptoms but whose heart pumping strength is largely preserved. It aims to better understand this specific type of heart failure and how best to treat or evaluate it.
AbercynonAges 18 years+ - NCT03450577Recruiting
Bifurcation heart artery registry study for adults
This registry study looks at adults with a specific kind of blockage pattern where a heart artery splits. By collecting information about these cases, the study aims to better understand treatment and outcomes for this condition.
Novosibirsk, Novosibirsk OblastAges 18–100
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,973 recruiting cardiology studies from the U.S. registry right now, out of 15,205 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.