Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT06492044Recruiting
Testing right heart strain to predict fluid response in septic shock
This study tests whether measuring the strain (stretch) of the right upper heart chamber with ultrasound can predict if a patient with septic shock will benefit from more fluids. Septic shock is a severe infection that causes very low blood pressure and organ damage.
AmiensAges 18 years+ - NCT06352307Recruiting
Prevention and treatment strategies for arrhythmogenic cardiomyopathy
This trial evaluates early prevention and treatment strategies for arrhythmogenic cardiomyopathy (ACM), a heart condition that can cause abnormal heart rhythms. It aims to improve care by using advanced tests like heart imaging and genetic sequencing to guide treatment.
Xi'an, ShaanxiAges 18 years+ - NCT05965362Recruiting
Study biomarkers to predict outcomes in heart infection
This study looks at blood and other lab test results (“biomarkers”) to better predict what may happen to people with infective endocarditis, a serious infection of the heart lining or heart valves. Your information may help doctors estimate risk and choose care more safely and effectively.
Xi'an, ShaanxiAges 18 years+ - NCT05775432Recruiting
Study outcomes for people receiving heart transplants
This study follows people with severe (end-stage) heart failure who are evaluated for and receive a heart transplant. It helps doctors understand what outcomes to expect after transplant, which can guide future care.
Xi'an, ShaanxiAges 3–80 - NCT05999188Recruiting
Aortic dissection study in China
This study looks at the features and outcomes of aortic dissection in Chinese patients. It aims to better understand the condition and improve care.
Xi'an, ShaanxiAges 18–80 - NCT06100328Recruiting
Cardiac tumor study tracking health outcomes
This study looks at people with different types of heart tumors to better understand their risks and outcomes. It aims to improve how doctors predict and manage future health events.
Xi'an, ShaanxiAges 3–80 - NCT06010199Recruiting
Biomarker risk study for myocarditis patients
This study looks at certain markers in your blood to better understand the risk level of myocarditis (inflammation of the heart muscle). It may help doctors know how to best monitor and treat your condition.
Xi'an, ShaanxiAges 3–80 - NCT06141525Recruiting
Remote conditioning for safer heart bypass recovery
This study tests whether a simple, non-invasive treatment called remote ischemic conditioning (using a blood pressure cuff on your arm) can help patients recover better after off-pump heart bypass surgery. The goal is to see if it reduces complications and improves heart function.
Xi'an, ShaanxiAges 18–70 - NCT06199401Recruiting
Testing a new surgery for type A aortic tear
This trial tests a new surgical method (XJ-Procedure) for people with an acute tear in the upper part of the main artery from the heart (type A aortic dissection). It may offer a safer option for those needing 'Sun's procedure' surgery.
Xi'an, ShaanxiAges 18–70 - NCT06319846RecruitingPhase 3
Tirofiban for recent mild stroke or TIA with narrowed brain artery
This trial tests the drug tirofiban (a blood thinner) to prevent another stroke in people who have had a mild stroke or high-risk TIA and have a narrowed artery in the brain. It must be started within 24 hours of symptoms.
Harbin, HeilongjiangAges 40 years+ - NCT06352320Recruiting
Improving care for cardiomyopathy patients
This trial aims to better understand and treat cardiomyopathy by studying patients' hearts with advanced tests. It seeks to find new ways to prevent or manage the condition early.
Xi'an, ShaanxiAges 18–80 - NCT06478576Recruiting
Study of a new stent graft for thoracoabdominal aortic aneurysm
This trial tests a new multibranched stent graft system to treat thoracoabdominal aortic aneurysms. It may help patients who have an aneurysm that is large, growing quickly, or causing symptoms like pain.
BeijingAges 18–80 - NCT06500728Recruiting
Vision involvement in giant cell arteritis
This study looks at how vision is affected in people with giant cell arteritis (GCA) -- a condition where blood vessels become inflamed. It compares those with GCA-related vision loss to people who have similar vision problems but not from GCA, to better understand and treat these eye issues.
Milan, LombardyAges 18 years+ - NCT06474819Recruiting
Comparing two pacemaker lead placements to protect heart function
This study compares two ways of placing a pacemaker lead to see if one protects your heart's pumping ability better over time. It may help prevent heart muscle weakness caused by pacing.
BarcelonaAges 18 years+ - NCT06225752RecruitingPhase 3
Probucol for recent stroke or mini-stroke from narrowed arteries
This study tests whether the drug probucol can help people who recently had a stroke or mini-stroke caused by a narrowed artery in the brain or neck. It aims to reduce the risk of future strokes.
WuhuAges 40 years+ - NCT05835791Recruiting
Study of new ventricular arrhythmia patients getting ICD follow-up
This study looks at people who are newly diagnosed with a dangerous heart rhythm called ventricular tachycardia (VT) and who are getting an implantable cardioverter-defibrillator (ICD). It may help improve how patients are followed in the ICD clinic after the initial hospitalization.
Vancouver, British ColumbiaAges 18 years+ - NCT06503107RecruitingPhase 1/Phase 2
Nanobody-based CAR-T cells for multiple myeloma
This trial tests a new type of CAR-T cell therapy that targets a protein called BCMA on your myeloma cells. It is for people with multiple myeloma that has not responded to or has come back after several prior treatments.
Wuhan, HubeiAges 18–75 - NCT07807423Recruiting
Artificial intelligence guidance for atrial fibrillation ablation
This study tests whether an AI software can help doctors identify which people with persistent atrial fibrillation might need more than just a standard ablation procedure. The software analyzes heart signals during the ablation to guide treatment, potentially improving outcomes for people whose condition is more complex.
AvignonAges 18 years+ - NCT07808931Recruiting
Long flight after cosmetic surgery: effect of seat class and compression stockings on leg vein swelling
This study looks at how different seating classes (business/first vs. economy) and wearing compression stockings on long flights affect leg vein swelling after cosmetic surgery. Participants will have an ultrasound to check the veins before and after the flight.
BogotáAges 18–65 - NCT07808411Recruiting
Leg vein size changes in the first two days after long flights to Bogota
This study measures the size of a vein in your leg before, during, and after a long flight to Bogota. It aims to understand how flying affects that vein, which may help prevent blood clots. You must be flying to Bogota for at least 4 hours and be willing to have several vein ultrasounds.
BogotáAges 18–65 - NCT07803835RecruitingPhase 1
Study of MWX401 for healthy adults and mild high blood pressure
This study tests a new medicine, MWX401, to see if it is safe and how it works in the body. It includes healthy adults and people with mild high blood pressure, with frequent check-ups to ensure safety.
Nanjing, JiangsuAges 18–60 - NCT07803822RecruitingPhase 2
New drug alone or with inclisiran for high cholesterol and triglycerides
This study tests a new investigational drug called MWX203, given alone or with another medicine (inclisiran), to lower both 'bad' cholesterol (LDL) and triglycerides in people with mixed dyslipidemia. The goal is to see if the combination is safe and works better than statins alone.
Beijing, Beijing MunicipalityAges 18–75 - NCT07800962Enrolling by invitation
Comparing bedside heart ultrasound to standard echocardiography
This study looks at whether a quick ultrasound done at the bedside (point-of-care) can give similar information to a full echocardiogram. Participants must be adults having both tests within 24 hours of each other, and their medical data must be available for research.
New York, New YorkAges 18 years+ - NCT06022653Recruiting
Aorta and peripheral artery disease registry
This study collects information from people who have had treatment for aorta or peripheral artery disease at Asan Medical Center since 2011. It helps researchers understand how patients are doing over time.
SeoulAges 19 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.