Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,973 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2481
- Phase 4480
- Phase 3447
- Phase 1360
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke843
- Heart Failure565
- Hypertension399
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma333
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke138
- Myocardial Infarction101
- Pulmonary Hypertension100
- Stroke, Ischemic86
- Congenital Heart Disease85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California461
- Alabama197
- Massachusetts183
- Arizona173
- New York161
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,970 total
- NCT06875154Enrolling by invitation
How original tricuspid valve disease affects new valve lifespan
This study looks at how the type of tricuspid valve problem you had originally (narrowing, leaking, or both) might affect how long a replacement valve lasts. If you have had only tricuspid valve replacement surgery, this trial could help doctors understand your long-term outcome better.
MaastrichtAges 18 years+ - NCT07400406Recruiting
A new MRI test to see calcified heart arteries
This trial tests a special MRI using a contrast agent called ferumoxytol to better see calcium buildup in heart arteries. It may help people who need a coronary angiogram and have some calcium visible on a prior CT scan.
Nanjing, JiangsuAges 18–75 - NCT06324461RecruitingPhase 4
GLP-1 drug to protect heart after non-emergency surgery
This study tests whether a GLP-1 receptor agonist (a medication used for diabetes and weight loss) can reduce heart damage during or after planned non-cardiac surgery. It may help patients with heart risk undergoing intermediate to high-risk procedures.
Hong Kong, Hong Kong SARAges 18 years+ - NCT07396857Recruiting
Sitting and blood pressure study for healthy adults
This study tests how substances from your blood vessels (EDHFs) help control blood pressure after you sit for a long time. It may help explain why sitting too much is bad for your heart.
Halifax, Nova ScotiaAges 18–65 - NCT07077824Recruiting
Nerve block to reduce artery catheter complications in heart surgery
This trial tests whether a nerve block (stellate ganglion block) can reduce complications from placing an artery catheter during heart surgery. It is for people with weak heart function (EF below 35%) or severe lung hypertension who are expected to have a long surgery.
CairoAges 18 years+ - NCT07270536Recruiting
Pacing and heart pressure in HFpEF exercise
This study tests whether a special pacing setting during exercise can help improve heart filling pressures in people with heart failure with preserved ejection fraction (HFpEF) who already have a DDD pacemaker. If you have HFpEF and a pacemaker, you may help researchers find better ways to manage your condition during activity.
HasseltAges 18 years+ - NCT05812248Recruiting
Tracking heart and blood vessel events after major non-heart surgery
This study follows people after major surgery to see what predicts heart and blood vessel problems later. It does not test a new drug; it mainly collects health information to help clinicians reduce risk.
Guangzhou, GuangdongAges 45 years+ - NCT07500077Recruiting
Strength and balance for older adults in cardiac rehab
This research study tests whether adding strength and balance exercises to your regular cardiac rehab class can help older adults feel stronger and more steady on their feet. It is for people who are already taking part in a maintenance cardiac rehab program in Scotland.
GlasgowAges 50–100 - NCT06291805Recruiting
Understanding wtATTR-CM heart disease (TRACE 1)
This study aims to better understand a type of heart disease called wild-type transthyretin amyloid cardiomyopathy (wtATTR-CM). It will compare people with this condition to a control group without known heart disease to identify key features.
Aarhus, Arrhus NAges 18 years+ - NCT07503522Recruiting
Personalized music and exercise for stroke recovery
This study tests whether adding personalized music to gentle aerobic exercise helps people recovering from a recent stroke improve faster. It's for patients in the early weeks or months after stroke who can sit, understand instructions, and don't have major heart or thinking problems.
Ho Chi Minh City, Ho Chi MinhAges 18 years+ - NCT02803294RecruitingPhase 4
Study of heart valve replacement outcomes in Chinese patients
This study records results of a minimally invasive procedure to replace a narrowed or leaking heart valve. It may help doctors understand how well the treatment works and what complications happen in Chinese patients.
Hanzhou, ZhejiangAges 18 years+ - NCT07696936Recruiting
Robot vs manual arm artery brain scan trial
This trial tests if a robot can help perform a brain artery scan through the wrist as safely and effectively as the standard manual method. It might be an option if you need a detailed look at blood vessels in your brain.
Shijiazhuang, HebeiAges 18–80 - NCT07611045Recruiting
Understanding recovery and care after heart surgery
This study asks patients and their families about their experience after heart surgery (like bypass or valve repair) to help doctors improve follow-up care. You'll share your story through an interview, and your feedback could help future patients.
Bristol, BristolAges 18 years+ - NCT07503236Recruiting
Study of a new device for leaking heart valves
This trial tests a new device designed to fix a leaky mitral valve in people with heart failure. It may help you breathe easier and feel less tired if your valve leak is severe and medicines have not been enough.
Sacramento, CaliforniaAges 21 years+ - NCT04944615Recruiting
IVUS-guided stent placement for blocked heart artery using longer guidance
This trial compares two ways to place a stent (a small mesh tube) for a completely blocked heart artery: using an IVUS camera inside the artery versus using a standard x-ray approach. It may help people get better heart outcomes by improving how accurately the stent is placed in long-term blockages.
BeijingAges 18 years+ - NCT07506382Recruiting
Comparing two self-expanding aortic valves in TAVR
This study compares two types of self-expanding aortic valves used during a minimally invasive procedure called TAVR. It aims to see which type works better in everyday practice.
Montpellier, OccitanieAges 18 years+ - NCT07508007Recruiting
Study on improving Lp(a) testing in heart clinics
This trial tests ways to help doctors check for high Lp(a), a risk factor for heart disease, in patients who need it. The study looks at whether special strategies increase testing rates in cardiology centers that currently test less than 15% of eligible patients.
NurembergAges 18 years+ - NCT07257289Recruiting
Heart risk study for inherited heart conditions
This study looks at people with inherited heart diseases and their relatives to better predict risks of dangerous heart rhythms or heart failure. It may help find out if you or your family members need closer monitoring.
BordeauxAges 1–100 - NCT07077395RecruitingPhase 2
Hot flash study to check heart health links
This study looks at how hot flashes in midlife women might be connected to heart disease risk. Researchers want to see if managing hot flashes can improve heart health.
Boston, MassachusettsAges 40–65 - NCT07605715Recruiting
Catheter vs. Surgery for Leaky Mitral Valve
This study compares two ways to fix a leaky mitral valve (a heart valve that doesn't close properly): one using a thin tube inserted through blood vessels (catheter) versus traditional open-heart surgery. The goal is to see which approach works better and is safer for older adults.
Los Angeles, CaliforniaAges 60 years+ - NCT07257367Recruiting
Pressure sensing sheath vs. traditional blood pressure monitoring in wrist procedures
This trial compares a new pressure-sensing sheath that monitors blood pressure during wrist-artery procedures to the traditional method. It aims to see if the new device works just as well or better, and is for patients who are already scheduled for a planned (not emergency) procedure needing continuous blood pressure monitoring.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06669520Recruiting
Renalase and blood vessel blockages after heart attack
This study is looking at a protein in the blood (renalase) and how it relates to blockages in tiny blood vessels after a heart attack. Researchers want to see if this protein can help predict recovery, which could lead to better treatments.
Changsha, HunanAges 18 years+ - NCT07247487Recruiting
Diet and Heart Health in Rosario
This study looks at how different diets (vegan, vegetarian, or omnivorous) affect heart health and metabolism in Rosario. It's a good fit if you're a generally healthy adult who has been following one of these diets for at least a year.
Rosario, Santa Fe ProvinceAges 18–65 - NCT07522580Recruiting
Heart Fluid Response Monitoring in Critically Ill Children
This study tests a simple, non-invasive device that measures how well a child's heart responds when doctors give extra fluids during intensive care. It helps doctors decide if more fluids will actually help the child feel better.
Le Plessis-Robinson, FranceAges birth–8 years
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,973 recruiting cardiology studies from the U.S. registry right now, out of 15,205 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.