Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,973 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2481
- Phase 4480
- Phase 3447
- Phase 1360
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke843
- Heart Failure565
- Hypertension399
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma333
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke138
- Myocardial Infarction101
- Pulmonary Hypertension100
- Stroke, Ischemic86
- Congenital Heart Disease85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California461
- Alabama197
- Massachusetts183
- Arizona173
- New York161
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,970 total
- NCT06861075Recruiting
Carvedilol for high blood pressure in liver veins
This trial tests whether a medicine called carvedilol can lower high blood pressure in the liver veins of people with cirrhosis. It uses a special ultrasound probe to measure the pressure before and after taking the medicine.
Clermont-FerrandAges 18 years+ - NCT06334003Recruiting
Heart health in moms and babies after fertility treatment
This study looks at how fertility treatments affect the heart and metabolism of mothers and their children. It compares women who became pregnant with or without fertility help to understand any differences.
CopenhagenAges 18–40 - NCT07179705Recruiting
Predicting low blood pressure during dialysis in the ICU
This trial tests if a special tool can predict and prevent dangerous drops in blood pressure during dialysis in ICU patients with kidney problems. It might help make dialysis safer and more comfortable.
BangkokAges 18 years+ - NCT07178769Recruiting
Testing a supplement for lowering cholesterol
This trial tests a nutritional supplement with bergamot, artichoke, and other natural ingredients to see if it can safely lower cholesterol in people with moderately high LDL. It may be an option for those not currently on other cholesterol treatments.
Madrid, MadridAges 18 years+ - NCT06175754Recruiting
Laser or injection for leg veins
This study compares two treatments for small leg veins (reticular veins): a laser treatment and a sclerotherapy injection. It aims to see which works better for women.
TambovAges 18–75 - NCT06823700Recruiting
Study of SQ-Kyrin device for leaky mitral valve from heart failure
This trial tests a new device (SQ-Kyrin) to fix a leaky mitral valve without open-heart surgery. It is for people with heart failure whose valve leak causes symptoms, and who are not good candidates for traditional surgery.
Valladolid, ValladolidAges 18 years+ - NCT07116733RecruitingPhase 3
Comparing two anesthetics for heart bypass surgery
This trial compares two types of anesthesia (desflurane gas vs. propofol IV) during coronary artery bypass surgery to see which one is better for your heart. It might help patients who are having planned bypass surgery.
Fuzhou, FujianAges 18 years+ - NCT07157449Recruiting
ECG markers for subcutaneous defibrillator eligibility
This study looks at electrocardiogram (ECG, a heart rhythm test) markers to see who might be eligible for a subcutaneous defibrillator (a device placed under the skin to prevent sudden cardiac arrest). If you are seeing a cardiologist for any reason and are over 18, you may be able to join.
Nantes, NantesAges 18 years+ - NCT06833827Recruiting
Clot removal vs clot-busting drugs for severe lung clots
This study compares two ways to treat a large blood clot in the lungs that is causing life-threatening symptoms. One method uses a device to remove the clot, the other uses medicine to dissolve it.
Leiden, South HollandAges 18 years+ - NCT05342233Recruiting
Compare watchful care versus catheter treatment for a bowel artery tear
This study compares two ways to treat an isolated tear in the superior mesenteric artery (a blood vessel that supplies the intestines): conservative (watchful care) versus endovascular (catheter-based) treatment. It may help doctors figure out which approach works best for people whose condition is confirmed on a CT angiogram and who are stable enough for either plan.
Changsha, HunanAges 18 years+ - NCT06828575Recruiting
Testing AI models on artery pressure readings
This study tests how well artificial intelligence can analyze artery pressure waveforms during surgery. If you're having scheduled surgery and already need this monitoring, your data might help improve patient care.
IstanbulAges 18 years+ - NCT06345443Enrolling by invitation
Nicotinamide riboside for blood vessel health
This trial tests a nutritional supplement (nicotinamide riboside) to see how it affects blood flow in healthy adults. It may help understand how to support vascular health as we age.
Rochester, MinnesotaAges 35–70 - NCT06275555Recruiting
Bivalirudin for blood thinning in ECMO patients
This trial tests if bivalirudin is a safe and effective blood thinner for people on ECMO, a machine that helps your heart and lungs. You may be eligible if you need this therapy and have no past reactions to similar medicines.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06274645Recruiting
Study of IVUS for Complex Heart Procedures
This study will look at how using a special ultrasound (IVUS) during a heart procedure (PCI) can help people with complex blockages, such as heavy calcium or multiple narrowings. It aims to see if this approach improves outcomes.
ShanghaiAges 18 years+ - NCT07627009Recruiting
Arm Exercises With and Without Deep Breathing After Heart Surgery
This study tests whether doing arm exercises combined with deep breathing helps recovery after open-heart surgery. Researchers want to see if breathing exercises during movement improves lung function and overall healing in patients recovering in the ICU.
İzmit, KocaeliAges 18 years+ - NCT06437886Enrolling by invitation
Comparing high-dose vs. lower-dose opioid anesthesia for heart surgery
This trial compares two types of anesthesia during heart surgery: one that uses high doses of strong painkillers (opioids) and one that uses less opioids. The goal is to see which approach is safer and helps patients recover better.
BeijingAges 45–70 - NCT06410313Recruiting
New drug-coated stent for thigh artery disease
This study tests a new drug-coated stent to improve blood flow in the thigh artery for people with leg pain or discomfort from narrowed arteries. It aims to see if the stent is safe and works well.
Atlanta, GeorgiaAges 18–120 - NCT07282301Recruiting
Filter to catch debris during leg artery cleaning
This trial tests a special filter that catches debris during a procedure to clear blockages in the leg artery (the one behind the knee). It aims to reduce the risk of debris traveling to smaller blood vessels, which can cause complications. If you have a hardened leg artery and plan to have plaque removal before a stent or balloon, this study may be for you.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06744413Recruiting
Prehabilitation to improve heart rate variability before cancer surgery
This trial tests whether a personalized prehabilitation program, delivered via a smartphone app, can improve heart rate variability (a measure of nervous system health) in people preparing for major cancer surgery. Participation may help you recover better after surgery.
CataniaAges 18 years+ - NCT03232918RecruitingPhase 4
Oxytocin effects on baby’s heart rate during labor
This study looks at how oxytocin (a labor-inducing/strengthening medicine) may affect your baby’s heart rate during labor. It also compares what happens when labor pain relief is given as a spinal/epidural injection.
Iowa City, IowaAges 18–55 - NCT02798731Recruiting
Testing blood vessel function after a heart transplant
This trial measures how well tiny blood vessels in the heart are working in people who have had a heart transplant. It may help doctors understand transplant-related circulation problems and guide future care.
SeoulAges 18–85 - NCT06872021Recruiting
Early balloon pump use after heart-lung bypass
This trial tests if using a heart pump (IABP) early after starting a life support machine (VA-ECMO) helps people recover from cardiogenic shock. It looks for patients whose heart is not pumping well despite support.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07051603RecruitingPhase 1
Safety study of SAL0140 in healthy Chinese adults
This study tests the safety and how the body handles a new medicine (SAL0140) in healthy people. It helps doctors find the right dose and check for side effects.
Guangzhou, GuangdongAges 18–65 - NCT07497295Recruiting
Ultrasound to predict blood pressure drop during prostate surgery
This study uses ultrasound to measure how much the veins in your leg and belly collapse when you breathe, to see if this can predict a drop in blood pressure during spinal anesthesia for prostate surgery. If you are eligible, you may help doctors better manage your blood pressure during surgery.
Antalya, MuratpasaAges 18–75
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,973 recruiting cardiology studies from the U.S. registry right now, out of 15,205 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.