Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,973 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2481
- Phase 4480
- Phase 3447
- Phase 1360
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke843
- Heart Failure565
- Hypertension399
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma333
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke138
- Myocardial Infarction101
- Pulmonary Hypertension100
- Stroke, Ischemic86
- Congenital Heart Disease85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California461
- Alabama197
- Massachusetts183
- Arizona173
- New York161
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,970 total
- NCT07049991Recruiting
Observatory for Para-Prosthetic Heart Valve Leak Closure
This study collects information from people who are having a procedure to close a leak around a previously placed artificial heart valve. The goal is to better understand how these procedures work and what happens to patients afterwards.
Le Plessis-RobinsonAges 16 years+ - NCT07615868RecruitingPhase 1
New blood-thinner study for heart disease patients in China
This study tests a new medication called selatogrel in people with chronic coronary syndrome (long-term heart disease caused by narrowed heart arteries). Researchers want to see how the body processes this drug and whether it helps prevent future heart problems.
BeijingAges 18–85 - NCT07525843Recruiting
Well-being education program for teens with heart disease
This study tests whether a special education program about managing emotions and stress helps teenagers with moderate-to-severe congenital heart disease (a heart condition from birth) feel better and cope with their condition. Participants attend sessions and complete surveys over time.
Stanford, CaliforniaAges 12–17 - NCT06764953Recruiting
Amnion membrane graft for non-healing leg ulcers
This study tests a special amnion membrane graft to help heal chronic leg ulcers that haven't improved with standard care. The graft is placed on the wound to support healing, and results are compared with standard treatment alone.
Roanoke, VirginiaAges 18 years+ - NCT06762964RecruitingPhase 2
Dapagliflozin for Failing Fontan Circulation
This study tests whether a medication called dapagliflozin (a pill for heart failure) can help people with a Fontan circulation who feel short of breath. It aims to improve symptoms and quality of life.
Rochester, MinnesotaAges 18 years+ - NCT07613632Recruiting
Lung Blood Flow Changes After Vein Graft Repair
This study measures how blood flow and oxygen distribution in your lungs change after a procedure to unclog a dialysis access graft. Researchers use painless electrode patches on your chest to track these changes and better understand how the procedure affects your breathing.
WuhuAges 18 years+ - NCT06860698Recruiting
E-cigarettes and blood vessel health in young adults
This study looks at how using e-cigarettes with nicotine affects the small blood vessels in young adults. It compares regular e-cigarette users to non-users to understand potential health impacts.
Richmond, VirginiaAges 18–29 - NCT06930456Enrolling by invitation
Comparing two drugs to prevent low blood pressure during spinal anesthesia
This study tests if giving hydrocortisone (a type of steroid) or ondansetron (an anti-nausea drug) before spinal anesthesia can better prevent low blood pressure during surgery for your belly or lower leg.
Port Said, Port Said GovernorateAges 21 years+ - NCT06690333Recruiting
Comparing leadless pacemakers to left bundle area pacing
This study compares two types of pacemakers: a small leadless pacemaker (placed directly in the heart without wires) and a newer pacing technique called left bundle area pacing. It aims to see which is safer and works better for people who need a pacemaker due to heart block or after a TAVR procedure.
Naples, FloridaAges 18 years+ - NCT07622823Recruiting
Nerve Blocks to Reduce Pain After Heart Surgery
This study tests whether special numbing injections around nerves (called fascial plane blocks) can help reduce pain and improve recovery after planned heart surgery. The goal is to see if this technique helps patients manage pain better and recover faster.
AntalyaAges 18 years+ - NCT07053605Recruiting
Laparoscopic splenic artery aneurysm repair, spleen saved
This study tests a keyhole surgery (laparoscopy) to remove an aneurysm from the splenic artery while saving your spleen. It may help people with larger, growing, or ruptured splenic artery aneurysms.
Yangzhou, JiangsuAges 18 years+ - NCT06930092Recruiting
Stents to improve heart function in heart failure
This study tests whether opening blocked heart arteries with stents can improve heart function in people with heart failure caused by coronary artery disease. It may be an option if your heart is weak and you have multiple blockages but no recent heart attack or dangerous rhythm.
Seoul, Chongno-guAges 19 years+ - NCT06247384Recruiting
Predicting low blood pressure during major abdominal surgery
This trial tests a tool that predicts drops in blood pressure during major abdominal surgery. It may help doctors manage blood pressure better during and after surgery.
Poznan, PoznańAges 18–80 - NCT07237971Recruiting
Making medicine use better in Elche
This study works with the community to find ways to use medications like antidepressants, blood pressure drugs, and antibiotics more wisely. It is a collaboration among residents, healthcare workers, and local groups to create solutions together.
Elche, AlicanteAges 18 years+ - NCT07453381Recruiting
New catheter to check small heart vessels in people with chest pain
This trial tests a special wireless pressure catheter to see how well the tiny blood vessels in the heart are working. It may help people who have chest pain but don't have major blockages in their main heart arteries.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06228209Recruiting
Palliative care for advanced heart failure or cancer
This study tests whether adding a palliative care specialist to your regular care team can improve your quality of life if you have advanced heart failure or advanced lung or certain gastrointestinal cancers. It is for people who have been in the hospital recently and live in Manhattan.
New York, New YorkAges 18 years+ - NCT07226479Recruiting
Non-invasive vein pressure test for heart patients
This study tests if a non-invasive method can estimate central venous pressure, reducing the need for invasive catheters in heart patients.
New Haven, ConnecticutAges 18 years+ - NCT06702059Recruiting
Heart exercise test for bypass surgery patients
This trial uses a special exercise test to measure heart and lung function in people scheduled for coronary artery bypass surgery. It may help doctors understand how well patients recover after surgery.
Brno, Czech RepublicAges 18 years+ - NCT06702553RecruitingPhase 3
Nitric oxide to reduce support after heart surgery
This trial tests whether giving nitric oxide gas during heart surgery can help patients recover faster and need less breathing and circulation support afterward. It is for people having planned heart or aortic surgery with a heart-lung machine for the first time.
Boston, MassachusettsAges 18 years+ - NCT07603765Recruiting
Heart Rhythm Monitoring During Ablation Procedures
This study examines a minimally invasive way to monitor your heart's blood pressure and function during a cardiac ablation procedure—a treatment that corrects irregular heartbeats. The goal is to better understand how this monitoring technique works and helps doctors manage your care during the procedure.
IstanbulAges 18 years+ - NCT07696884Recruiting
Vascular graft and endograft infection study
This study looks at how the body responds to infections in artificial blood vessels (vascular grafts or endografts). It may help understand why some people get infections and how to better treat them.
AarhusAges 18 years+ - NCT07601269RecruitingEarly Phase 1
New Mitral Valve Implant for Heart Valve Disease
This early-stage trial tests a new device called the ReValve System that replaces a damaged mitral valve (the valve that controls blood flow in your heart). The study is for people with a weakened heart who have leaking mitral valves and are experiencing heart failure symptoms.
São Paulo, São PauloAges 18 years+ - NCT06745466RecruitingPhase 4
Stress, sleep, and hormones on heart health in midlife women
This study looks at how daily stress, sleep, and sex hormones affect blood vessel aging in women aged 40–55 who are still having regular periods. It may help understand why heart disease risk increases during this time.
Newark, DelawareAges 40–55 - NCT02397668Recruiting
New tricuspid valve replacement for leaky or absent valve
This study tests a special replacement valve (an “ECM valve”) for people whose tricuspid valve is leaky or missing and needs surgery. It may help restore blood flow on the right side of the heart and is designed for certain children born with congenital heart problems.
Mobile, AlabamaAges 1–85
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,973 recruiting cardiology studies from the U.S. registry right now, out of 15,205 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.