Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,973 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2481
- Phase 4480
- Phase 3447
- Phase 1360
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke843
- Heart Failure565
- Hypertension399
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma333
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke138
- Myocardial Infarction101
- Pulmonary Hypertension100
- Stroke, Ischemic86
- Congenital Heart Disease85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California461
- Alabama197
- Massachusetts183
- Arizona173
- New York161
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,970 total
- NCT07059715Recruiting
Studying blood flow during heart surgery for vasoplegia risk
This study looks at blood flow in small and large vessels during heart surgery to understand and predict vasoplegic syndrome, a dangerous drop in blood pressure. It may help find patients at risk and improve their care.
ParisAges 18 years+ - NCT07580443Recruiting
Quality of Life After Open Surgery for Complex Aortic Aneurysms
This study follows patients who have had open surgery to repair complex abdominal aortic aneurysms—bulges in the main blood vessel in the belly. Researchers will ask you about your quality of life after surgery to understand how well people recover and feel.
LucerneAges 18 years+ - NCT05828862Recruiting
Checks blood-pressure drops during major upper stomach surgery
This trial studies what happens when blood pressure drops during planned (elective) major upper gastrointestinal surgery and looks at related blood chemistry. Your care team may collect samples during the operation to understand why this happens and how to improve outcomes.
TaipeiAges 20–80 - NCT06692309Recruiting
Can brain wave patterns predict thinking problems after heart surgery?
This study uses a brain wave recording device (EEG) during heart surgery to see if it can predict short-term confusion or memory problems after the operation. It may help doctors find and treat thinking issues earlier.
Beijing, Beijing MunicipalityAges 60 years+ - NCT07181356Recruiting
Remote Ischemic Preconditioning for Heart Attack Recovery
This study tests whether a simple, noninvasive procedure called Remote Ischemic Preconditioning (RIPC) — where a blood pressure cuff is briefly tightened on an arm or leg — can improve long-term recovery for people who have had a heart attack. The treatment is done many times over a long period to see if it helps the heart heal and reduces future problems.
Zhengzhou, HenanAges 18 years+ - NCT06978660Recruiting
AI-powered ECG test for early cardiac amyloidosis
This trial tests if an AI can spot early signs of cardiac amyloidosis from a standard 10-second ECG. If successful, it could lead to faster diagnosis and treatment.
Evanston, IllinoisAges 18 years+ - NCT07581431RecruitingPhase 1
Testing ISM8969 in healthy and obese adults with heart disease risk
This early-stage trial tests a new drug called ISM8969 to see if it's safe and how the body handles it. Participants are either healthy adults or adults who are overweight with risk factors for heart disease, like high blood pressure or high cholesterol.
Melbourne, VictoriaAges 18–80 - NCT05147831Recruiting
Remote arm treatment to prevent kidney injury from contrast dye
This trial tests whether a simple “arm conditioning” technique done remotely before a procedure can help prevent kidney injury caused by contrast dye used during certain heart catheter tests. You might benefit if you’re having a coronary angiogram and your kidney function is reduced, but you’re not on dialysis.
Galveston, TexasAges 18 years+ - NCT07549477Recruiting
Heart imaging study for cancer patients with catheter clots
This study uses a special heart imaging test (cardiac MRI) to look for and understand blood clots that may form around central catheters (tubes placed in veins) in people with cancer. The imaging helps doctors see if clots are present and what type they are, which could improve how they care for cancer patients.
Basking Ridge, New JerseyAges 18 years+ - NCT07093788Recruiting
Comparing two ways to treat hard calcium in heart arteries
This trial tests two methods for breaking up heavy calcium buildup in heart arteries before placing a stent. It compares a specialized high-pressure balloon to a device that uses shockwaves.
Lianyungang, JiangsuAges 18–80 - NCT07195149RecruitingPhase 3
Aspirin dose comparison after bypass surgery
This trial tests whether a lower dose of aspirin combined with another blood thinner (prasugrel) after bypass surgery is as safe and effective as a higher dose. It is for people with stable heart disease who are scheduled for bypass surgery and have not had a recent heart attack.
BialystokAges 18 years+ - NCT07339475Recruiting
Using vein size to predict blood pressure drops in older adults during hip or leg surgery
This study uses an ultrasound to measure the size of a vein in your leg before surgery to see if it can predict a drop in blood pressure during the procedure. If you are over 60 and having planned lower-limb surgery with spinal anesthesia, this non-invasive test might help your doctors prepare for your care.
CairoAges 60 years+ - NCT07085299Recruiting
Gut bacteria and recovery in brain artery narrowing
This study looks at how the bacteria in your gut might affect outcomes in people with narrowed brain arteries. Researchers will track your health over time to see if there are links between your gut bacteria and your recovery.
Nanjing, JiangsuAges 30–80 - NCT07550738Recruiting
Breathing machine settings during laparoscopic cancer surgery
This study compares two different ways of controlling breathing machines during laparoscopic (minimally invasive) abdominal cancer surgery. Researchers want to see which method keeps your heart and blood flow stable and protects your lungs during surgery.
AsyutAges 20–80 - NCT07712900Recruiting
Nutrition counseling for diabetes and high blood pressure
This trial tests whether nutrition counseling helps people who have both type 2 diabetes and high blood pressure. It aims to improve their heart and metabolic health.
DessieAges 18 years+ - NCT05666518Recruiting
Study of vericiguat safety in Japanese chronic heart failure patients
This study checks how safe the medicine vericiguat is for Japanese people with chronic heart failure when used in everyday care. It compares patients who receive vericiguat with patients who continue standard treatments without vericiguat.
Multiple Locations, Many LocationsAges Any age - NCT07101289Recruiting
Eat Well Heart Failure Coaching Study
This study is testing a virtual health coaching program that helps people with heart failure eat better when they have trouble affording food. The program may help prevent future hospital stays and improve your health.
Durham, North CarolinaAges 18 years+ - NCT07095790RecruitingPhase 4
Tirofiban plus aspirin and clopidogrel for mild stroke
This trial tests whether a combination of a clot-preventing drug (tirofiban) followed by two antiplatelet drugs (aspirin and clopidogrel) can improve recovery in people who have had a mild stroke. It aims to find a better way to prevent further strokes or worsening symptoms.
Suzhou, AnhuiAges 18–80 - NCT05784753Recruiting
Exercise coaching for adults with heart failure and preserved heart strength
This study tests an exercise-focused program (including coaching/support) for adults with heart failure where the pumping strength is preserved. It may help improve exercise ability and daily function while monitoring safety.
Detroit, MichiganAges 18 years+ - NCT07166822Recruiting
Can a mobile app help you stay active during pregnancy?
This study tests if using a mobile app can help pregnant women who are not very active to exercise more safely and improve their heart health. It's for women with low-risk pregnancies who want to use a simple smartphone tool.
Norfolk, VirginiaAges 18–45 - NCT07713017Recruiting
Exercise after heart bypass surgery
This study looks at how combining aerobic exercise with strength training can help people recover after coronary artery bypass graft (CABG) surgery. If you had a successful bypass with no complications and are willing to join a heart rehab program, this trial may be a good fit for you.
Sialkot, Punjab ProvinceAges 30–60 - NCT05991700RecruitingPhase 1/Phase 2
Grape Powder to Prevent Irregular Heartbeat After Valve Surgery
This trial tests whether a grape powder supplement (rich in plant compounds called anthocyanins) can help prevent a common heart rhythm problem (atrial fibrillation) after mitral valve repair surgery. It is for people who are scheduled for this surgery and do not have certain heart or health issues.
Ann Arbor, MichiganAges 18–79 - NCT05974462RecruitingPhase 3
Steroids for mild heart inflammation with weaker pumping
This trial tests whether a course of steroid medicine can improve outcomes in people with recently started myocarditis (heart muscle inflammation) and mildly reduced heart pumping. It compares steroids versus placebo (inactive treatment) to see if steroids help the heart recover and prevent worsening.
Edegem, AntwerpAges 18–69 - NCT05216731Recruiting
Compare bypass versus stent treatment for leg artery blockages
This study compares two ways to treat long blockages in the superficial femoral artery (a main artery in the thigh): bypass surgery versus an endovascular (stent/through-a-vessel) procedure. It may help people with painful leg claudication to choose the approach most likely to keep blood flowing and improve symptoms.
BordeauxAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,973 recruiting cardiology studies from the U.S. registry right now, out of 15,205 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.