Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT07784751Enrolling by invitationPhase 1/Phase 2
Ultrasound therapy for stroke recovery
This study tests a new treatment that uses ultrasound pulses to help people recover after a stroke. It may improve movement or language abilities.
Taipei, TaiwanAges Any age - NCT07785765Enrolling by invitation
Exercise study for people recovering from SCAD
This study tests whether a supervised exercise program is safe and helpful for people who have had a spontaneous coronary artery dissection (SCAD), a tear in a heart artery. It may help improve your recovery and heart health.
OsloAges 18 years+ - NCT07786649Recruiting
Non-invasive brain stimulation for stroke recovery
This trial tests different types of non-invasive brain stimulation to see which one helps people recover better from stroke-related problems like arm weakness, leg weakness, neglect, or speaking difficulty.
SingaporeAges 21–80 - NCT06473740RecruitingPhase 4
Gene therapy plus angioplasty for severe leg blockages
This study tests if adding gene therapy to a standard leg artery-opening procedure (angioplasty or stenting) helps people with severe leg pain or non-healing wounds due to blocked arteries. It may improve blood flow and save the leg from amputation.
Blagoveshchensk, Amur OblastAges 18 years+ - NCT07790458Recruiting
Automated blood pressure cuff study
This study tests a new automatic blood pressure cuff that may work as well as the standard invasive blood pressure monitor. It is for adults in the operating room, recovery room, or intensive care unit who already have an arterial line.
HelsinkiAges 18 years+ - NCT07784296Recruiting
Triple combination therapy for high blood pressure in Korean adults
This study tests a three-drug combination pill for high blood pressure in Korean adults. It aims to see if this treatment is safe and effective.
Gyeonggi-doAges Any age - NCT07792239RecruitingPhase 2
Study of budiodarone for atrial fibrillation
This study tests a new medicine, budiodarone, to help control atrial fibrillation (an irregular heartbeat) in people who haven't been helped by other treatments. It may reduce the time spent in AF and improve symptoms.
GdyniaAges 18–80 - NCT07786779RecruitingPhase 1
Safety study of an injectable drug in healthy adults
This study tests a new injectable medication to see if it is safe and how the body processes it. It is looking for healthy adults to participate and will monitor for side effects and study how the drug works.
Beijing, Beijing MunicipalityAges 18–55 - NCT07785141Recruiting
Monitoring heart oxygen during pediatric open-heart surgery
This study uses a non-invasive light-based technique to monitor oxygen levels in the heart muscle during open-heart surgery in children. It aims to see if this method can help doctors better manage the surgery and improve outcomes.
Helsinki, UusimaaAges 1–17 - NCT07787091RecruitingPhase 1/Phase 2
First study of ARD001 in healthy people and those with hemophilia A
This study tests a new medicine, ARD001, for the first time in humans. It aims to see if the drug is safe and how the body handles it, and it is also being studied in people with hemophilia A to find a safe dose for future trials.
SingaporeAges 21–45 - NCT07791160Recruiting
A study of acoramidis for people with transthyretin amyloid cardiomyopathy
This study is testing a medication called acoramidis for people with a heart condition called transthyretin amyloid cardiomyopathy (ATTR-CM). It aims to see how well the treatment works in a real-world setting in France.
Many LocationsAges 18 years+ - NCT01390675Recruiting
Registry for heart valve replacement anesthesia during TAVR
This study tracks patients who get a transcatheter aortic valve implantation (TAVR), a procedure to replace a narrowed heart valve without open-heart surgery. It looks at the type of anesthesia used during the procedure and records outcomes to learn what works best for patients.
Munich, BavariaAges 18 years+ - NCT06539689Recruiting
Sperstent for remaining blockages after balloon treatment in leg arteries
This trial tests a special stent called Sperstent for people who still have blockages or tears in their leg arteries after balloon treatment. It is designed to help improve blood flow and reduce symptoms like leg pain or sores.
Beijing, Beijing MunicipalityAges 18–85 - NCT06538974Recruiting
Long-term use of an exoskeleton for leg weakness
This trial tests a walking device called an exoskeleton to help people with leg weakness or movement problems. It's designed to see if using the exoskeleton regularly over time can help improve walking or mobility.
ParisAges 18 years+ - NCT04937699RecruitingPhase 4
Switching anti-platelet tablets after a heart stent
This trial studies whether changing the timing and type of blood-thinner tablets after a heart stent is as safe and effective as continuing the same plan. It may help some people by simplifying treatment while preventing dangerous clotting after a coronary procedure.
Hangzhou, ZhejiangAges 18–80 - NCT06541860Recruiting
Study of daratumumab and lenalidomide for resistant multiple myeloma
This trial tests a combination of two drugs, daratumumab and lenalidomide, for patients with multiple myeloma that has not responded to previous treatments. It aims to see if this regimen can help when other therapies have stopped working.
Pavia, PVAges 18 years+ - NCT06542822Recruiting
IV iron for non-ischemic heart failure with low iron
This study tests whether intravenous iron can improve outcomes for people with non-ischemic heart failure and low ejection fraction who are also iron deficient. If you fit the criteria, you may receive iron infusions to see if it helps your heart function and symptoms.
Southampton, HampshireAges 18 years+ - NCT06546761Recruiting
Heart imaging after carotid artery treatment
This study tests whether imaging the heart's arteries with a special CT scan can help find hidden blockages in people who just had treatment for a blocked carotid artery. It aims to prevent future heart problems.
RigaAges 50 years+ - NCT06545591Recruiting
Predicting stroke treatment success with a blood test
This trial studies a blood marker called sTREM to see if it can help predict outcomes after a mechanical clot removal procedure (endovascular thrombectomy) for large-vessel stroke. If you have had a stroke due to a large artery blockage within the last 24 hours and plan to have this procedure, you may be able to join.
Xuzhou, JiangsuAges 18 years+ - NCT06311149Recruiting
Study of LATITUDE heart device monitoring
This trial looks at how well the LATITUDE monitoring system works for people with heart devices. It checks if remote monitoring helps doctors track how your device is doing, so they can spot problems early.
FerraraAges Any age - NCT06548737Recruiting
Outcomes after a brain bleed
This study looks at what happens to people after a bleed in the brain. It will help doctors understand how people recover, so they can improve care for future patients.
Hangzhou, ZhejiangAges 18–100 - NCT06548477Recruiting
Albumin for recovery after brain aneurysm bleed
This study tests whether giving the protein albumin can improve recovery after a brain aneurysm has burst. It is for people who have had their aneurysm treated quickly after symptoms started.
DohaAges 18–80 - NCT07775976Enrolling by invitation
Whole-heart checkup with a wearable heart monitor
This study looks at how well a wearable heart monitor and special software can check the health of your whole heart and assess your risk of future heart problems. It may help doctors create more personalized care plans.
Pasadena, CaliforniaAges 18 years+ - NCT07783802RecruitingPhase 2
Study of clazakizumab for adults with high inflammation and heart risk
This study tests whether clazakizumab can reduce the risk of heart attacks or strokes in people with high levels of inflammation (measured by a blood test called hsCRP) and conditions like heart disease, obesity, diabetes, high blood pressure, or kidney disease. If you qualify, you'll receive either the study drug or a placebo to see if it helps lower your risk.
Huntsville, AlabamaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.