Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,973 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2481
- Phase 4480
- Phase 3447
- Phase 1360
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke843
- Heart Failure565
- Hypertension399
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma333
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke138
- Myocardial Infarction101
- Pulmonary Hypertension100
- Stroke, Ischemic86
- Congenital Heart Disease85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California461
- Alabama197
- Massachusetts183
- Arizona173
- New York161
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,970 total
- NCT06230198Recruiting
Effect of a blood-saving technique on transfusions after heart surgery
This trial tests whether a technique called retrograde autologous priming (using the patient's own blood to prepare the heart-lung machine) can reduce the need for blood transfusions during heart surgery. It is looking at hospitals and surgical teams, not individual patients, so it's not a typical trial you can join directly.
Winnipeg, ManitobaAges 10–110 - NCT07090876Recruiting
Grape seed extract for blood pressure
This trial tests whether a grape seed extract supplement can help people with slightly high blood pressure (called high-normal) improve their heart health. It may be an option if your blood pressure is borderline and you are not taking blood pressure medications.
Bologna, BoAges 18–70 - NCT06478017RecruitingPhase 2
Belatacept for heart transplant patients
This study tests whether a drug called belatacept can safely help your body accept a new heart without rejecting it, and may reduce the need for other strong immune-suppressing medicines. If you are getting a heart transplant for the first time and have certain immune markers, this trial may be an option for you.
Los Angeles, CaliforniaAges 18–71 - NCT07061548Recruiting
Predicting heart output changes during surgery using capnography
This trial uses a computer algorithm to predict changes in how well your heart pumps blood during surgery. It looks at carbon dioxide levels in your breath to make these predictions. This could help doctors adjust care in real time.
SeoulAges 19–75 - NCT05795036Recruiting
Fitbit and text tips to boost walking after heart rehab
This study tests whether a phone-based program (Fitbit plus text messages and calls) helps people walk more during Phase III cardiac rehabilitation. It may help you build safer, healthier physical activity as part of your recovery plan.
Orlando, FloridaAges 18–99 - NCT07520565RecruitingPhase 3
Emergency stroke treatment with BXOS110 within 3 hours
This trial tests whether BXOS110, an experimental injection, can help people recover better after an acute ischemic stroke (a stroke caused by a blood clot) when given within 3 hours of symptom onset. The study compares BXOS110 to a placebo to see if it reduces disability and improves recovery.
Hengshui, HebeiAges 18–85 - NCT06246396RecruitingPhase 4
Minocycline for resistant high blood pressure
This study tests whether minocycline, a common antibiotic, can help lower blood pressure in people whose high blood pressure is not controlled by multiple medications. If you have resistant hypertension, this trial may offer a new option to better manage your condition.
Gainesville, FloridaAges 18–100 - NCT07618416Recruiting
Blood Pressure Prediction Before Anesthesia in Older Adults
This study tests a computer model that uses heart-rhythm measurements to predict whether your blood pressure will drop dangerously after anesthesia begins. If accurate, it could help doctors prepare and protect you during surgery.
Beijing, ChinaAges 65 years+ - NCT06937827Recruiting
Heart failure follow-up clinic after hospital discharge
This program offers phone follow-ups after you leave the hospital to help manage your heart failure. It is for people who had a recent heart failure flare-up but are going straight home without homecare or hospice services.
Brick, New JerseyAges 18–90 - NCT06341010Recruiting
AngioJet for new leg vein clots
This study tests a special device called AngioJet to remove fresh blood clots from the large veins in your leg or pelvis. The goal is to see if it helps prevent long-term damage like leg swelling or pain.
AsyutAges 18–60 - NCT06691217RecruitingPhase 2
Testing an Anti-Inflammatory Drug for Heart Disease With TET2 Mutation
This study tests whether a medication that blocks inflammation (called an IL-1 beta inhibitor) can reduce blood vessel inflammation in people with both heart disease and a specific genetic change in their blood cells (TET2 mutation). It aims to see if targeting this type of inflammation can help lower heart risks.
Boston, MassachusettsAges 18 years+ - NCT07100457Recruiting
OR6A2 on immune cells and heart recovery after heart attack
This study looks at a molecule called OR6A2 on certain immune cells (monocytes) in people who have had a heart attack treated with a stent. It aims to see if this molecule is linked to heart recovery and future heart problems.
Nanjing, JiangsuAges 18–90 - NCT06986187Recruiting
Predicting difficult airways in heart surgery patients
This study measures how often difficult airways occur during heart or blood vessel surgery and builds a way to predict them beforehand. It may help your care team prepare for safer airway management during your procedure.
AnkaraAges 18 years+ - NCT07126028Enrolling by invitation
Quality of life in kids after MIS-C
This study looks at how children feel and live their daily lives after recovering from MIS-C (a severe inflammatory condition linked to COVID-19). It compares them to healthy children of the same age and gender to see if there are any lasting effects.
Rijeka, Primorje-Gorski Kotar CountyAges 1 month–18 years - NCT06089486Recruiting
New Heart Scan for Transplant Patients
This study investigates a new heart scan (called a cardiac PET) to detect early signs of blood vessel disease in heart transplant patients. If you had your transplant 2 to 10 years ago, this scan might be an alternative to the usual yearly checkup with an invasive procedure (angiogram).
Calgary, AlbertaAges 18 years+ - NCT07172620Recruiting
Heart bypass surgery without clamping the aorta
This study tests a special technique for heart bypass surgery that avoids clamping the aorta. It may help people with hardened arteries in the aorta who need bypass surgery but are not good candidates for standard clamping.
Beijing, Beijing MunicipalityAges Any age - NCT07541092Recruiting
Optrell Catheter for Heart Rhythm Problems from Papillary Muscles
This study compares how well a special heart mapping catheter (Optrell) works in treating irregular heartbeats that start in specific heart muscle areas called papillary muscles. If you're having frequent or bothersome extra heartbeats, this trial may help you get a procedure your doctor already recommends.
New Hyde Park, New YorkAges 18–75 - NCT06059976Recruiting
Hypnosis during heart surgery recovery study
This study looks at the use of hypnosis during heart surgery to see how it affects recovery. If you are having major heart surgery and have already had hypnosis sessions before, during, or after the operation, you may be eligible to participate.
GrenobleAges 18 years+ - NCT06524440Recruiting
Hypertensive heart disease study in DR Congo
This trial studies people with hypertensive heart disease in DR Congo. It aims to learn more about the condition.
KinshasaAges 18 years+ - NCT06040073Recruiting
Study of heart artery blockages after heart attack
This study is for people who recently had a heart attack and need an angiogram. It looks at blockages that are not completely blocking blood flow to learn how they change over time.
BeijingAges 18 years+ - NCT07044128Recruiting
Testing a new electronic stethoscope for heart murmur checks
This study is testing a new electronic stethoscope (called Keikku) to see if it works well and is safe for checking heart murmurs in children and adults who are not in an emergency situation. If it works, it could give doctors a better tool for evaluating heart sounds.
LimaAges Up to 99 years - NCT05868902Recruiting
Study registry of heart imaging for suspected blocked heart flow
This study collects results from two types of heart imaging—cardiac PET and CardioFlux magnetocardiography—in people with suspected reduced blood flow to the heart. It may help researchers better understand which imaging findings match coronary ischemia and how the tests compare.
Cleveland, OhioAges 40 years+ - NCT05131750Recruiting
Study how RIR affects outcomes after heart stent procedures
This trial looks at a factor called RIR and whether it changes health outcomes for people with coronary heart disease who get a PCI (a heart stent procedure) while in the hospital. It may help doctors understand who benefits and how to improve care after stenting.
Wuhan, HubeiAges 18–80 - NCT06518317RecruitingPhase 3
Short vs Long Blood Thinner Use After TAVI
This trial compares a short course versus a longer course of antiplatelet medicine (blood thinners) after a TAVI procedure for aortic stenosis. It aims to see which approach is safer and more effective.
CaenAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,973 recruiting cardiology studies from the U.S. registry right now, out of 15,205 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.