Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,973 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2481
- Phase 4480
- Phase 3447
- Phase 1360
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke843
- Heart Failure565
- Hypertension399
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma333
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke138
- Myocardial Infarction101
- Pulmonary Hypertension100
- Stroke, Ischemic86
- Congenital Heart Disease85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California461
- Alabama197
- Massachusetts183
- Arizona173
- New York161
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,970 total
- NCT06707454Recruiting
Recovery after open heart surgery in older adults
This study looks at how older adults recover after open heart surgery, focusing on brain and nerve health. It may help researchers understand the effects of surgery on thinking and memory.
CairoAges 60 years+ - NCT07221695Enrolling by invitation
Pelvic vein treatment: foam plus glue vs foam plus coils
This trial compares two different methods for treating chronic pelvic pain caused by pelvic vein disorders. One method uses foam plus a medical glue, the other uses foam plus tiny metal coils. The goal is to find which approach works better.
Kafr ash Shaykh, Kafrelshaykh GovernorateAges 18–50 - NCT06351150RecruitingPhase 3
Testing angiotensin II for refractory distributive shock
This study tests an injection of angiotensin II (a substance that helps tighten blood vessels) versus a placebo for patients with distributive shock that is not responding to standard treatments. It may help raise blood pressure and improve outcomes.
Hefei, AnhuiAges 18 years+ - NCT07081009Recruiting
Heart injury after planned back surgery study
This study is looking at whether patients having planned lower back surgery experience any heart stress afterward. It aims to understand how common this is and what might help protect the heart.
AnkaraAges 18 years+ - NCT07431762RecruitingPhase 4
Aspirin vs. Warfarin after bioprosthetic valve surgery
This trial compares aspirin to warfarin in the first six months after receiving a bioprosthetic (tissue) heart valve. It aims to find which treatment better prevents blood clots without causing excessive bleeding.
OsakaAges 19 years+ - NCT06372054Recruiting
Predicting health risks for Italian Air Force members
This study aims to develop smart risk models using your body's data (like proteins and genes) along with personal exposure readings. It will help predict health risks for Italian Air Force personnel. You will wear a monitor and give samples, then be followed over time.
MilanAges 26–38 - NCT06032195RecruitingPhase 2
Study of heart preservation in children needing a first transplant
This study looks at how the heart muscle is kept healthy after donation and before transplant in children. It aims to improve transplant success.
BerlinAges 1 day–17 years - NCT07611019Enrolling by invitationPhase 2/Phase 3
Colchicine to prevent heart rhythm problems after heart bypass surgery
This study tests whether taking colchicine (a common anti-inflammatory medication) before and after bypass heart surgery can prevent atrial fibrillation—an irregular heartbeat that sometimes occurs after surgery. Researchers hope this simple treatment might reduce complications and improve recovery.
TaipeiAges 20 years+ - NCT07365345Recruiting
Electrical Stimulation for Low Blood Pressure During TAVR
This study tests whether electrical stimulation at specific points on the body can help prevent low blood pressure during TAVR, a minimally invasive heart valve procedure. It may help people who are at risk for blood pressure drops during surgery.
Xi'an, ShannxiAges 60 years+ - NCT07603648Recruiting
How different pacemaker lead positions affect heart rhythm signals
This study looks at how placing a pacemaker lead (a thin wire) in different spots in the upper heart chamber affects electrical signals. It may help doctors choose the best position for future pacemakers.
Zunyi, GuizhouAges 18 years+ - NCT07634640RecruitingEarly Phase 1
Testing an Inflammation Treatment for Heart Failure
This early-stage trial tests a new approach to treat heart failure with preserved ejection fraction (HFpEF)—a type of heart failure where the heart's pumping strength is normal, but it doesn't relax properly. Researchers believe inflammation plays a role and want to see if targeting it can help patients feel better and function more easily.
Gainesville, FloridaAges 18–85 - NCT07537296Recruiting
Heart Imaging Study After Heart Attack
This study uses advanced CT scans to take detailed pictures of your heart and blood vessels after a recent heart attack treated with stent placement. The goal is to better understand heart damage and predict long-term outcomes.
Nanjing, JiangsuAges 18 years+ - NCT07363538Recruiting
Comparing heart surgery methods for newborns with complex heart defects
This trial tests new surgical strategies for newborns with certain complex heart conditions. It aims to see which techniques lead to better recovery and quality of life in the first year after surgery.
Beijing, Beijing MunicipalityAges Up to 1 week - NCT06226987Recruiting
Heart imaging study for Fabry disease
This study uses special MRI scans to look at how Fabry disease affects the heart. It may help researchers understand the disease better.
Cambridge, CambridgeshireAges 18 years+ - NCT07718113Recruiting
Exercise Snacking and Heart Health
This study tests whether short 'exercise snacks' (brief bursts of activity throughout the day) can improve your heart and metabolic health. It's for people who are currently not very active and want to see if small, frequent exercise breaks can make a difference.
River Falls, WisconsinAges 18–60 - NCT07066449Recruiting
Testing a new ultrasound system for heart surgery
This study is testing a new ultrasound system that takes pictures of your heart from inside your esophagus during surgery. It is for people who are already scheduled for this type of imaging as part of their procedure.
NanjingAges 18 years+ - NCT05089149Recruiting
Check how lung ultrasound helps manage heart failure congestion
This study looks at people with long-term worsening heart failure who are coming to the hospital for a planned visit, to see how checking “congestion” (fluid buildup) may guide care. It may help the team understand whether lung ultrasound can better assess who needs treatment changes.
Vandœuvre-lès-NancyAges 18 years+ - NCT07684924Recruiting
Early FAPI PET/MRI after a heart attack
This study uses a new type of PET/MR scan (FAPI) to look at inflammation in the heart shortly after a heart attack. It may help doctors understand recovery better and guide future treatments.
AnkaraAges 18–90 - NCT07525518Enrolling by invitation
Okami Medical Device Patient Registry
This is a registry—a database that tracks patient outcomes—for people receiving Okami Medical devices. By joining, you help doctors understand how well these devices work and whether they're safe over time.
Aurora, ColoradoAges 18 years+ - NCT05097898Recruiting
Check fluid buildup in heart failure with normal pumping
This study evaluates how well doctors can assess “fluid congestion” in people with chronic heart failure where the heart’s squeezing is still preserved. It may help improve how patients are monitored during hospital visits.
Vandœuvre-lès-NancyAges 18 years+ - NCT07538115Recruiting
Better Heart Monitoring During Sedation for Digestive Procedures
This study compares two ways of monitoring your heart and vital signs during a sedated procedure to examine your digestive tract (ERCP). Researchers want to see if more detailed monitoring helps keep you safer during the procedure.
ÇorumAges 18 years+ - NCT07082283Recruiting
Atrial pacing and heart function after cardiac surgery
This study looks at how a short burst of electrical pacing to the upper chambers of the heart affects blood flow and heart function after cardiac surgery. It may help doctors find better ways to support recovery.
BeirutAges 18 years+ - NCT06721455Recruiting
Blood Management Study for Pediatric Heart Surgery
This study looks at how managing blood products during heart surgery with a heart-lung machine affects the risk of red blood cell breakdown in children. The goal is to find safer ways to handle blood during these procedures.
Boston, MassachusettsAges birth–17 years - NCT06872905Recruiting
Long-term results of a stent used for aortic repair
This study is checking how well a specific stent (VBX) works over time when used in a procedure called CERAB to treat blocked arteries in the lower belly and pelvis. If you had this procedure at least a year ago, your experience could help doctors understand how well this treatment lasts.
Fresno, CaliforniaAges 18–100
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,973 recruiting cardiology studies from the U.S. registry right now, out of 15,205 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.