Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,976 recruiting studies in this area right now.
By phase
- Not applicable7,959
- Phase 2483
- Phase 4479
- Phase 3447
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke841
- Heart Failure567
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma334
- Atrial Fibrillation268
- Ischemic Stroke201
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke137
- Myocardial Infarction102
- Pulmonary Hypertension100
- Congenital Heart Disease85
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California460
- Alabama197
- Massachusetts183
- Arizona174
- New York161
- Florida145
- Maryland120
- Illinois119
- Minnesota119
- Texas118
Recruiting studies9,973 total
- NCT05440422RecruitingPhase 2
Anifrolumab for heart and blood vessel health in lupus
This trial tests whether a drug called anifrolumab can improve early signs of heart and blood vessel damage in people with lupus. It may help prevent future heart problems and strokes.
Bethesda, MarylandAges 18–80 - NCT06121336Recruiting
Tracking a blood marker to measure stroke recovery
This study is looking at a protein in the blood called brain-derived tau, which may increase after a stroke. By measuring it over time, doctors hope to learn more about how the brain is healing and possibly predict recovery.
Munich, BavariaAges 18 years+ - NCT07777406Recruiting
Real-world study of donor stem cell transplant for relapsed/refractory myeloma
This study looks at real-world outcomes in patients who have had a donor stem cell transplant for multiple myeloma that has come back or not responded to treatment. It aims to gather info on how well this approach works in everyday practice.
Chieti, CHAges 18 years+ - NCT07762664Recruiting
Photon-counting CT versus regular CT for evaluating carotid artery narrowing before stenting
This study compares two types of CT scans to evaluate the arteries in your neck before you have a stent placed. The newer photon-counting CT may provide more detailed images, which could help your doctor plan the procedure more precisely.
Beijing, Beijing MunicipalityAges 10–90 - NCT07351656Recruiting
AI heart checks for young adults, adults, and pregnant women
This study uses artificial intelligence (AI) to look at heart signals (electrocardiography or ECG) and ultrasound images of the heart to check for heart disease. It aims to better understand heart health in different groups of people.
Rochester, MinnesotaAges 18 years+ - NCT07777445Recruiting
Oxygen treatment during exercise for lung and pulmonary vascular disease
This study compares breathing normal air versus low-flow liquid oxygen during exercise to see if oxygen helps improve performance in people with conditions affecting the lungs or the blood vessels in the lungs. You would exercise while using a portable oxygen device and then without it to compare the effects.
Zurich, Canton of ZurichAges 18 years+ - NCT07775742Recruiting
Exercise programs after heart bypass surgery
This study compares two exercise programs for people who have recovered from heart bypass surgery. One program involves high-intensity interval training, and the other is a home-based rehabilitation program. The goal is to see which program helps improve recovery and overall health.
MadinahAges 55–58 - NCT07773064Recruiting
Eye scan and blood test to predict heart disease risk
This study looks at whether images of the back of your eye and certain substances in your blood can help identify people at high risk for heart disease. If you're having tests for chest pain or other heart concerns, this research may help improve early detection.
Beijing, Beijing MunicipalityAges 18–100 - NCT07426419RecruitingPhase 1/Phase 2
Gene therapy for BAG3-related dilated cardiomyopathy
This trial tests a gene therapy (AFTX-201) for people with dilated cardiomyopathy caused by a BAG3 gene mutation. The therapy aims to improve heart function, and the study will check if it is safe and effective.
Miami, FloridaAges 18–70 - NCT07777367Recruiting
Exercise with liquid oxygen in chronic lung disease
This study compares how well people with chronic lung diseases perform during exercise when breathing regular air versus when using low-flow liquid oxygen. It aims to see if using liquid oxygen during exercise can improve exercise ability and quality of life.
Zurich, Canton of ZurichAges 18 years+ - NCT07776054RecruitingPhase 4
SGLT2 inhibitor after heart shock for atrial fibrillation with heart failure
This study tests whether a diabetes drug called an SGLT2 inhibitor can help keep your heart in a normal rhythm after a procedure to shock it back into rhythm. It is for people with persistent atrial fibrillation and a type of heart failure where the heart is stiff.
Seoul, SeoulAges 19 years+ - NCT05136859Recruiting
Predicting fistula success with blood tests and vessel checks
This study looks at whether blood markers and the condition of your blood vessels before surgery can predict how well a new dialysis access (fistula) will work. It aims to help doctors identify patients who may need extra care to ensure their fistula matures properly.
TaipeiAges 20 years+ - NCT04910568RecruitingPhase 1
Study of cevostamab for people with returning or hard-to-treat myeloma
This trial tests a new drug called cevostamab for people whose multiple myeloma has come back or stopped responding to treatment. It aims to see if the drug is safe and how well it works.
Duarte, CaliforniaAges 18 years+ - NCT07141355Recruiting
Empagliflozin's effect on small blood vessels in cardiogenic shock
This study looks at whether empagliflozin, a diabetes medicine, helps improve blood flow in tiny blood vessels for people in cardiogenic shock. If it helps, it could improve recovery for people with this serious heart condition.
StrasbourgAges 18 years+ - NCT07777744Recruiting
Study of serious complications during heart rhythm procedure
This study looks at the serious risks of a procedure that treats irregular heartbeats. It aims to understand how often complications happen and what they are, which can help doctors improve safety.
Chicago, IllinoisAges 18 years+ - NCT07776444Recruiting
Measuring brain blood flow with light and MRI
This study uses a special light-based device and MRI to measure how blood vessels in the brain respond to changes. It may help researchers better understand blood flow in people with and without sickle cell disease.
St Louis, MissouriAges 6–70 - NCT07067398Recruiting
Heart health program for home health aides
This study tests a program to help home health aides improve their heart health through coaching and support. Participants will get health checks and work with a peer coach to make healthy changes.
New York, New YorkAges 18 years+ - NCT07778823Recruiting
Augmented reality help for child CPR
This study tests if augmented reality (AR) glasses can help nurses and technicians give better CPR to children. AR glasses show helpful information right in your line of sight, which might make the process less stressful and more effective.
St. Petersburg, FloridaAges 18 years+ - NCT07310849Recruiting
Digital health support for older adults with diabetes
This study tests a digital care program using the LINE messaging app to help older adults with diabetes and other chronic conditions manage their health. It may be a good fit if you are 50 or older, have type 2 diabetes plus another condition like high blood pressure, and are comfortable using a smartphone.
New Taipei City, Wugu DistrictAges 50 years+ - NCT07780500Recruiting
Using electronic health records to study people with high blood pressure
This study is not testing a new medicine. Instead, it is using electronic health records to better understand people with high blood pressure, with a focus on those recently diagnosed. If you join, you may help researchers learn more about how to improve care for others with high blood pressure.
Oakland, CaliforniaAges 18 years+ - NCT07779213Recruiting
Smartphone camera test for atrial fibrillation
This study tests whether a smartphone camera can detect an irregular heartbeat (atrial fibrillation) by measuring blood flow through your fingertip. If it works, it could make checking your heart rhythm easier at home.
Jonesboro, ArkansasAges 22 minutes+ - NCT05585125RecruitingPhase 4
Testing an informed approach for older adults with HFpEF
This study looks at an “informed” approach to help manage HFpEF (a type of heart failure) in people age 65 and older. It checks whether a structured plan and monitoring are practical and safe for you over time.
New York, New YorkAges 65 years+ - NCT06084091Recruiting
Measuring heart oxygen levels during open-heart surgery
This study measures oxygen levels in the heart muscle during open-heart surgery using a light-based technique. You may qualify if you are an adult scheduled for this surgery and can provide consent.
Helsinki, UusimaaAges 18–90 - NCT07547540RecruitingPhase 1
Study of an investigational drug for heart failure
This study tests an experimental drug called LY3971297 to see if it can help people with chronic heart failure. It aims to find out if the drug is safe and if it improves heart function.
Detroit, MichiganAges 18–65
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,976 recruiting cardiology studies from the U.S. registry right now, out of 15,179 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Mental health
- Digestive system
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- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.