Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT04162444Recruiting
Aortic valve reconstruction study for children
This trial studies a surgery approach to help fix a narrowed or leaking aortic valve in children. It aims to see how well the reconstructed valve works and how it affects the child’s heart function over time.
MoscowAges 4 weeks–12 years - NCT04723888Recruiting
Supplements to slow aneurysm growth and prevent rupture
This trial studies whether alpha-ketoglutarate, a supplement, can slow the growth of an abdominal aortic aneurysm and reduce the risk of rupture. It may help people whose aneurysm size is in a specific range by tracking changes over time and watching for safety.
ShanghaiAges 50 years+ - NCT04305717Recruiting
Check fluid levels with a special sensor in hospitalized heart failure
This study uses a noninvasive device (ReDS) to estimate fluid buildup in people hospitalized with acute heart failure. It may help doctors monitor fluid status and guide care more accurately during a hospital stay.
New York, New YorkAges 18 years+ - NCT04776759Recruiting
Study of first atrial fibrillation in young adults
This study records and follows people under 35 who have their first episode of an irregular heartbeat. It aims to better understand this condition early on and how it shows up in real life.
Caen, NormandyAges Up to 35 years - NCT04822077Recruiting
Proton beam treatment for thymus tumors
This trial studies proton radiotherapy (a type of radiation) for cancers of the thymus, like thymoma or thymic carcinoma. It may help improve tumor control while limiting radiation exposure to nearby organs.
Umeå, NorrlandAges 18 years+ - NCT02814942Recruiting
Testing CRT in people with weak hearts and wide ECG signals
This study looks at whether a device called CRT (Cardiac Resynchronization Therapy) can help people with heart failure who have a weak heart pumping strength and a “wide” electrical signal pattern on an ECG. It may help some people feel better and improve heart function, especially if they are not already on the best standard medicines.
SingaporeAges 18 years+ - NCT04707105Recruiting
Study of brain bleeding in hospitalized adults
This study follows adults who are hospitalized after a type of brain bleed called primary intracerebral hemorrhage. It mainly tracks what happens after the bleeding to help doctors understand outcomes and care needs.
Hangzhou, ZhejiangAges 18 years+ - NCT04330651Recruiting
Extra-support machine for heart patients after surgery
This study looks at using an external life-support machine after heart surgery. It may help patients who need temporary extra support while the heart and body recover.
FlorenceAges 18–80 - NCT04742478Recruiting
Study of atherectomy and ultrasound for heavily calcified heart arteries
This study looks at how safe and effective a treatment is for heart artery blockages that are heavily hardened by calcium. It enrolls people who need a procedure to open the artery (with or without a stent) and whose blockage matches specific imaging or access problems.
KitakyushuAges 21 years+ - NCT04827498Recruiting
Testing heart blood-flow problems without clogged arteries
This study looks at how well the heart’s blood vessels work in people who have symptoms of reduced blood flow but no major artery blockage. It uses special heart tests with medicines to check how the vessels respond and may help guide better diagnosis and treatment.
MadridAges 18 years+ - NCT04286399RecruitingPhase 4
Prevention trial for heart outcomes in people with type 2 diabetes
This Phase 4 trial studies an approach to help prevent heart problems in adults with type 2 diabetes who are at higher heart risk. It may help reduce future cardiovascular events by testing medications for safety and benefit in this group.
SingaporeAges 40 years+ - NCT04879069Recruiting
Registry study for recent high-risk blood clot in the lungs
This trial is a registry that collects information about people with a recent lung blood clot diagnosed by CT scan. It particularly focuses on higher-risk cases to better understand outcomes and care in the first 2 weeks after symptoms start.
Poznan, GreaterPolandAges 18 years+ - NCT04377854Recruiting
Checking whether BNP predicts outcomes in advanced heart failure
This study looks at whether a blood test called BNP can help predict what happens over time in people being evaluated for advanced heart failure treatment. It may help doctors better plan care and follow-up for patients long-term.
Copenhagen, DKAges 18 years+ - NCT04898335Recruiting
Tendyne heart valve registry for real-world patient experiences
This registry collects information from people who received the Tendyne mitral valve in routine care. It helps doctors understand how the valve performs in everyday practice and may guide future care.
LinzAges 18 years+ - NCT04893603Recruiting
TAVR valve test for severe, hard-to-pump heart valve
This trial studies whether a new through-the-blood-vessel heart valve (TAVR) is safe and works well for people with severe aortic stenosis who are too risky for traditional surgery. If you qualify, you would be closely followed to check your symptoms and valve function over time.
BeijingAges 70 years+ - NCT04903912Recruiting
Study of people with blocked blood vessels or aneurysms
This registry study follows people with peripheral artery disease (blocked leg arteries), certain carotid artery narrowing, or an abdominal aortic aneurysm. It may help doctors better understand these conditions and improve care over time.
NaplesAges 18–90 - NCT04914468Recruiting
Study registry for mitral valve replacement by catheter
This study keeps a registry of adults who have a mitral valve problem and are being evaluated for a catheter-based mitral valve replacement. It helps doctors understand what treatments are used and how patients do.
HamburgAges 18–110 - NCT04906356Recruiting
Study of SCAD after a heart attack or unstable chest pain
This study looks at people admitted with a recent heart event (STEMI, NSTEMI, or unstable angina) and who were found to have SCAD on a heart scan. It may help doctors better understand and manage SCAD after these urgent events.
Vancouver, British ColumbiaAges 18 years+ - NCT04722796Recruiting
TAVR for bicuspid aortic valve with a specific device
This study tests a “solution” approach using a self-expanding valve during TAVR (a less invasive way to replace a narrowed aortic valve). It aims to improve how well the valve fits and works in people with a specific heart valve shape (bicuspid aortic stenosis).
Bengbu, AnhuiAges 60 years+ - NCT04191681RecruitingPhase 4
Testing ARNI in people with implanted LVAD devices
This trial studies whether a heart medicine called ARNI (sacubitril-valsartan) is safe and works well for people who have a durable LVAD and moderate-to-severe heart pumping weakness. It may help improve symptoms and outcomes, while carefully checking side effects in this higher-risk group.
Cleveland, OhioAges 18 years+ - NCT04815928Recruiting
Registry for people after heart artery procedures
This study is a patient registry that collects information from adults who have had (or will have) two types of heart procedures done to check and treat blocked coronary arteries. It helps doctors understand outcomes and care patterns after these procedures.
AmsterdamAges 18 years+ - NCT04954404Recruiting
Mitral valve procedure registry for Chinese patients in one center
This study is a registry (a way to track real-world outcomes) for people with mitral valve disease who receive a mitral valve procedure. It helps doctors understand how well these procedures work and what complications happen in patients like you.
Hangzhou, ZhejiangAges 18 years+ - NCT04962295Recruiting
Brain MRI study for small blood vessel changes
This study builds a brain imaging biobank for people with “small blood vessel disease” seen on MRI. Your MRI results can help researchers better understand these changes and track new events over time.
BeijingAges 18 years+ - NCT02803294RecruitingPhase 4
Study of heart valve replacement outcomes in Chinese patients
This study records results of a minimally invasive procedure to replace a narrowed or leaking heart valve. It may help doctors understand how well the treatment works and what complications happen in Chinese patients.
Hanzhou, ZhejiangAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.