Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,616 recruiting studies in this area right now.
By phase
- Not applicable5,344
- Phase 2606
- Phase 1557
- Phase 3418
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes275
- Diabetes192
- Diabetes Mellitus182
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Thyroid Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Johns Hopkins University38
Where studies are running
- California521
- Maryland180
- Alabama176
- Arizona170
- Florida166
- Texas159
- Massachusetts150
- New York144
- Colorado115
- Pennsylvania113
Recruiting studies7,616 total
- NCT05379712RecruitingPhase 2
Nutrition supplements during radiation for head and neck cancer
This trial studies whether a nutritional supplement helps people with head and neck squamous cell cancer when they are receiving radiation (with or without chemotherapy). You must be able to eat by mouth and have specific cancer types and recent CT imaging.
Edmonton, AlbertaAges 18 years+ - NCT04127552Recruiting
Adrenal mass screening and hormone effects on health
This study looks at how an accidentally found adrenal growth may affect heart and metabolic health, especially if it causes extra cortisol production. It may help explain which people are at higher risk and what monitoring or treatment could be useful.
Rome, ItalyAges 18–80 - NCT06164925Recruiting
Study on simplifying malnutrition screening for hospital patients
This study looks at a simpler way to diagnose malnutrition in adults who have just been admitted to the hospital. If you are over 18 and were admitted to Tartu University Hospital in the last 3 days, you may be able to join.
Tartu, TartuAges 18 years+ - NCT06562842Recruiting
Exercise, Gut Health, and Type 2 Diabetes Study
This study looks at how exercise affects gut bacteria in people with type 2 diabetes. It may help explain why physical activity improves diabetes control.
TrikalaAges 45–65 - NCT06594679RecruitingPhase 1/Phase 2
Study of niraparib and abemaciclib for advanced ovarian cancer
This trial tests a combination of two targeted drugs, niraparib and abemaciclib, for people with ovarian, fallopian tube, or primary peritoneal cancer that has come back after at least two prior chemotherapies. It may be an option if you have no standard treatments left and your cancer still responds to platinum-based chemotherapy.
Milan, MilanoAges 18 years+ - NCT06844539Recruiting
Helping beta cells to reverse type 2 diabetes
This study tests whether a treatment can help your pancreas make more insulin and possibly put your type 2 diabetes into remission. It is for people diagnosed with type 2 diabetes in the last 5 years who are already on diabetes medication.
Cambridge, CambridgeshireAges 18 years+ - NCT03594344Recruiting
Extra hyperbaric oxygen after leg amputation wounds heal
This study tests whether giving extra treatments with hyperbaric (pressure) oxygen after a leg amputation can improve healing or recovery. It’s meant for people whose amputation happened due to long-lasting infection or poor blood flow and who can attend follow-up visits.
OsloAges 18–90 - NCT02964637Recruiting
Tests to help diagnose frontotemporal dementia
This study looks at testing (including brain scans) to figure out what type of frontotemporal dementia or related language/speech condition a person has. It may help by making diagnoses more accurate, which can guide better care.
Toronto, OntarioAges 18–90 - NCT05030220Recruiting
Testing testosterone and a skin bacteria during shoulder surgery
This study looks at how testosterone levels and a common skin bacteria (Cutibacterium) may relate to outcomes around elective shoulder replacement surgery. Results could help improve how doctors prevent and understand infection risk or healing after surgery.
Seattle, WashingtonAges 18–89 - NCT05173597Recruiting
Real-world study of follitropin delta dosing in IVF
This study looks at how follitropin delta is used in real clinics to help women stimulate eggs for IVF or ICSI. It may help doctors fine-tune dosing by comparing outcomes in everyday practice.
Lübeck, Schleswig-HolsteinAges 18–44 - NCT04328337RecruitingPhase 1/Phase 2
Study tests how rising fatty acids affect brain fuel use
This early-phase study will raise fatty acid levels temporarily and see how the brain uses glucose (sugar) and processes energy. It may help researchers understand how metabolism in the body can change brain function.
Chapel Hill, North CarolinaAges 18–45 - NCT05581147Recruiting
Thyroid health in Klinefelter syndrome
This study looks at how the thyroid gland works and how it looks on ultrasound in people with classic (non-mosaic) 47,XXY Klinefelter syndrome. It may help doctors understand thyroid-related problems in this condition by comparing test results, symptoms, and imaging.
RomaAges 1–80 - NCT06487832Recruiting
Effect of diabetes drug on brain response to insulin
This study tests whether a GLP-1 receptor agonist (a type of diabetes medicine) changes how the brain responds to insulin in people with different body sizes. It may help understand if this drug can improve brain function related to insulin.
TübingenAges 18–70 - NCT06110143Recruiting
Gum health and pregnancy complications study
This study looks at how gum disease (periodontitis) during pregnancy might affect pregnancy outcomes. It may help you if you have gum disease and want to learn more about its impact on your pregnancy.
Holbæk, HolbaekAges 16–48 - NCT05848271Recruiting
Natural history study for people with HPDL gene changes
This study follows people who have an HPDL gene change to better understand how symptoms and health progress over time. It may help clinicians learn more about the condition and plan future treatments.
San Diego, CaliforniaAges Any age - NCT06522750Recruiting
Periodic fasting for long COVID in adults
This study tests whether periodic fasting can help adults with long COVID. You may qualify if you are 18-64, have had COVID symptoms for at least 12 weeks, have a normal weight and low iron stores.
EttelbruckAges 18–64 - NCT07252765Recruiting
Nutritional Drink for Diabetes with Malnutrition Risk
This study is testing whether a special diabetes drink (high in calories, protein, and fiber) helps people with type 2 diabetes who are at risk of malnutrition. If you have diabetes and have been prescribed this drink, you may be able to join.
Santander, CantabriaAges 18 years+ - NCT07253493Recruiting
Bone loss and nerve activity study for postmenopausal women
This study looks at how bone loss in the hip might affect nerve signals to muscles. It compares postmenopausal women with weak bones (osteoporosis in the hip) to those with normal bone density.
Bahçelievler, IstanbulAges 18–65 - NCT07250269RecruitingPhase 1
CAR-T therapy for AL amyloidosis
This trial tests a new CAR-T cell therapy (GC012F) that targets two proteins, CD19 and BCMA, on abnormal plasma cells. It's for people with AL amyloidosis who have already tried at least one treatment.
BeijingAges 18 years+ - NCT07251309RecruitingPhase 3
Study of WS016 for treating high potassium levels
This trial tests a new drug called WS016 to lower high potassium levels in adults. High potassium can be dangerous for your heart, and this study aims to find out if WS016 is safe and effective.
Bengbu, AnhuiAges 18 years+ - NCT07250828Enrolling by invitation
BurstDR spinal cord stimulation for painful diabetic neuropathy
This trial tests a type of spinal cord stimulation called BurstDR to see if it can reduce pain from diabetic nerve damage. It may help people with diabetes who have ongoing leg pain that hasn't gotten better with standard pain medications.
Grand Island, NebraskaAges 19 years+ - NCT07255404RecruitingPhase 2
Testing pumitamig with chemotherapy for untreated pancreatic cancer
This trial tests an experimental drug called pumitamig combined with standard chemotherapy for people with advanced pancreatic cancer that has spread and has not been treated yet. The goal is to see if this combination is safe and effective.
Bedford ParkAges 18 years+ - NCT07249788RecruitingPhase 4
Resmetirom for MASH: A study on safety and effectiveness
This trial tests if resmetirom can help people with MASH, a type of fatty liver disease linked to metabolic issues like diabetes or obesity. It looks at how safe and effective the drug is over time.
Rawalpindi, Punjab ProvinceAges 18–75 - NCT07252232RecruitingPhase 3
A pill to prevent pancreatic cancer recurrence after surgery
This trial tests an experimental daily pill, daraxonrasib, in people with pancreatic cancer that has been surgically removed. It’s for those who also had chemotherapy and have a specific DNA change called a RAS mutation. The goal is to see if the pill helps prevent the cancer from coming back.
Phoenix, ArizonaAges 18 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,616 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,939 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.