Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,628 recruiting studies in this area right now.
By phase
- Not applicable5,351
- Phase 2606
- Phase 1560
- Phase 3419
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 386
Top conditions
- Obesity618
- Ovarian Cancer336
- Pancreatic Cancer288
- Type 2 Diabetes277
- Diabetes192
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer86
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California521
- Maryland179
- Alabama176
- Arizona170
- Florida165
- Texas159
- Massachusetts151
- New York142
- Colorado115
- Pennsylvania114
Recruiting studies7,628 total
- NCT05577390Recruiting
Comparing two treatments for diabetic nerve pain
This study compares two approaches to treating nerve pain caused by diabetes. You may be eligible if your diabetic neuropathy is moderate to severe and you can reliably use a phone for study steps.
Loma Linda, CaliforniaAges 45–85 - NCT05996536Recruiting
Fat labeling study in familial partial lipodystrophy
This study tests a safe way to label fat (triglycerides) in people with a rare condition called familial partial lipodystrophy (FPL), where fat is missing in some areas. It involves two small fat biopsies, one from the belly and one from the thigh, to understand how the body handles fat.
Bethesda, MarylandAges 18–65 - NCT05983432RecruitingPhase 1
Study of BL-B01D1 for advanced lung and other solid tumors
This trial tests an experimental drug called BL-B01D1 for people with several types of advanced solid tumors, especially non-small cell lung cancer and breast cancer. It's designed for those whose cancer has continued to grow after standard treatments.
Beverly Hills, CaliforniaAges 18 years+ - NCT05974150Recruiting
Remote symptom monitoring for several blood and cancer types
This study checks how well remote (at-home) symptom check-ins work for people with certain cancers. It may help patients and clinicians spot problems earlier and improve day-to-day care during treatment and beyond.
New Haven, ConnecticutAges 18 years+ - NCT05984979Recruiting
Breath rhythms in people with and without diabetes
This study looks at how your breath changes throughout the day in people with and without diabetes. Researchers want to find patterns in breath chemicals that could help understand diabetes better.
BernAges 18 years+ - NCT05997810Recruiting
Parathyroid tumor genetics study
This study looks at the genetic makeup of parathyroid tumors in people with hyperparathyroidism. It aims to understand why these tumors form and how they behave, which could help improve treatment decisions.
St Louis, MissouriAges 18–80 - NCT05990192RecruitingPhase 2
SBRT with or without niraparib for ovarian cancer after PARP inhibitor treatment
This trial tests a new treatment approach for people with ovarian cancer that has started to progress in a few spots (up to 3) after taking a PARP inhibitor. It combines targeted radiation (SBRT) to those spots, followed by another PARP inhibitor (niraparib), to see if this can control the cancer further.
Leeds, LeedsAges 18 years+ - NCT05981222Enrolling by invitation
Osteo Match vs. PEEK cages for spinal fusion in osteoporosis
This study compares two types of cages used in spinal fusion surgery for people with osteoporosis. It aims to see if one type leads to better bone healing and stability.
Beijing, Beijing MunicipalityAges 50 years+ - NCT05985486Recruiting
Lifestyle change for brain health in Down syndrome
This study looks at how a healthy lifestyle program can improve brain health in adults with Down syndrome who are overweight or obese. You will attend a medical center three times over a year for tests, and you'll need a caregiver to support you.
Kansas City, KansasAges 18–64 - NCT05992532Recruiting
Study of rare enzyme disorders in monoclonal gammopathy or myeloma
This study looks for two rare inherited disorders—Gaucher disease and acid sphingomyelinase deficiency (ASMD)—in people who already have a blood condition like monoclonal gammopathy (abnormal protein) or multiple myeloma. If you have an enlarged spleen or low platelets, you may be eligible to help researchers understand if these rare diseases are more common in this group.
Vitoria-Gasteiz, AlavaAges 18–99 - NCT05982847Recruiting
Blood pressure check for kids in South Africa
This study checks blood pressure in children ages 5 to 17 across South Africa. It aims to find normal blood pressure ranges and improve healthcare for kids.
Mthatha, Eastern CapeAges 5–18 - NCT05975580RecruitingPhase 4
Medication plus lifestyle counseling for weight regain after bariatric surgery
This study looks at whether adding medication to lifestyle counseling can help people who have regained weight after sleeve gastrectomy or gastric bypass. It focuses on improving weight control and related health after surgery.
Orange, CaliforniaAges 18–70 - NCT05975541Recruiting
Infection risk in obesity and type 2 diabetes
This study looks at how obesity and type 2 diabetes affect your body's ability to fight infections. By joining, you'll help researchers understand why some people with these conditions get more infections, which could lead to better prevention and treatment.
Novara, NovaraAges 18–65 - NCT05973734Enrolling by invitationPhase 1
Islet transplant with immune cells to treat type 1 diabetes
This Phase 1 study tests a new immune-system strategy around islet transplantation (or donor bone marrow therapy) to improve control of type 1 diabetes and reduce dangerous low blood sugar. It mainly aims to see if the approach is safe and helpful in people with long-standing, difficult-to-manage diabetes.
Palo Alto, CaliforniaAges 18–70 - NCT05989347RecruitingPhase 1
Dapagliflozin with chemo for breast cancer
This trial tests whether adding the drug dapagliflozin (a pill that lowers blood sugar) to standard chemotherapy before breast cancer surgery can improve outcomes. It is for women with high insulin levels and a higher BMI who are about to start chemotherapy.
New Haven, ConnecticutAges 18 years+ - NCT05975593Recruiting
Study how radiation affects tumor biology in cervical or pancreatic cancer
This study looks at how radiotherapy changes the tumor environment, using lab samples collected during treatment. It may help researchers understand why radiation works differently for different people and could improve future treatment planning.
St Louis, MissouriAges 18 years+ - NCT05987410Recruiting
Nordic walking for weight and heart health after a cardiac event
This trial tests if a nordic walking program helps people with diabetes who are overweight or obese recover after a heart attack or heart procedure. If you had a heart event or stent/bypass in the last 3 months, this program could help you get stronger and manage your weight.
MilanAges 18 years+ - NCT03717844Recruiting
Registry for adults with plasma cell disorders
This study is a registry that collects information about adults with plasma cell disorders (conditions involving abnormal antibody-producing cells). It may help researchers understand these diseases better and improve future care by tracking patients over time.
Chapel Hill, North CarolinaAges 18 years+ - NCT04982744Recruiting
Li-Fraumeni and related syndrome patient registry
This is a research registry that collects information from people who have Li-Fraumeni or similar inherited cancer syndromes. It helps doctors better understand these conditions and improve future care.
Bologna, Emilia-RomagnaAges Any age - NCT05247645Recruiting
Collecting data from people with rare bone diseases
This study gathers information about people with rare illnesses that mainly affect the bones. It may help researchers better understand these conditions and improve future care.
Bologna, Emilia-RomagnaAges Any age - NCT05954416Recruiting
Study follow-up for rare skin and related genetic conditions
This study (a “cohort”) follows people with certain rare skin conditions over time. It helps doctors better understand these diseases and improve long-term care, and you may be asked to complete surveys.
BobignyAges Any age - NCT05945576Recruiting
RaDiCo IDMet study for people with inherited ID
This study enrolls people of all ages who have a confirmed inherited condition called ID. It collects information to better understand the condition and support future care.
AngersAges Any age - NCT05950659Recruiting
Wearable insoles to prevent repeat diabetic foot ulcers
This trial tests special sensory insoles (called Orpyx Sensory Insoles) to help prevent diabetic foot ulcers from coming back. It aims to reduce high-pressure foot spots for people who already had a healed nerve-related ulcer.
Baltimore, MarylandAges 18 years+ - NCT05946044Recruiting
Preventing Knee Arthritis in People at Higher Risk
This study looks at ways to help prevent knee osteoarthritis before it starts. It is designed for women with higher body weight who currently have no arthritis signs on scans and do not have much knee pain.
Boston, MassachusettsAges 50 years+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,628 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,015 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.