Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,640 recruiting studies in this area right now.
By phase
- Not applicable5,354
- Phase 2609
- Phase 1563
- Phase 3420
- Phase 4318
- Phase 1/Phase 2290
- Phase 2/Phase 386
Top conditions
- Obesity617
- Ovarian Cancer337
- Pancreatic Cancer290
- Type 2 Diabetes277
- Diabetes191
- Diabetes Mellitus184
- Diabetes Mellitus, Type 2172
- Hypertension138
- Type 1 Diabetes132
- Metabolic Syndrome128
- Obesity & Overweight125
- Breast Cancer112
- Overweight105
- Cardiovascular Diseases104
- Amyotrophic Lateral Sclerosis101
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer89
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California524
- Maryland178
- Alabama175
- Arizona171
- Florida164
- Texas159
- Massachusetts151
- New York143
- Colorado115
- Pennsylvania114
Recruiting studies7,640 total
- NCT04278404Recruiting
Drug safety study for children already on certain medicines
This study measures how certain medicines move through the body and checks their safety in children. It may help doctors better understand dosing and side effects in kids who are already receiving these treatments, or in some kids who recently tested positive for COVID-19.
Phoenix, ArizonaAges birth–20 years - NCT04258293Recruiting
Diabetes screening for people taking steroid tablets long term
This trial checks whether people who take steroid medicines for more than 3 months are developing early diabetes, using blood tests before and around starting treatment. It may help catch diabetes sooner if it’s starting to develop, even in people who didn’t have diabetes yet.
DijonAges 18 years+ - NCT04290663RecruitingPhase 3
Radioiodine decision after thyroid surgery for intermediate-risk cancer
This study compares two approaches after thyroid surgery: giving radioactive iodine right away versus deciding based on follow-up test results. It aims to see which approach better helps people with intermediate-risk differentiated thyroid cancer.
Pointe à Pitre, GuadeloupeAges 18 years+ - NCT04284943Recruiting
Surgery for stomach cancer and diabetes
This trial tests a surgery for early-stage stomach cancer that also aims to improve type 2 diabetes by changing how your body processes food. It might be an option if you have both conditions and are not using insulin.
SeoulAges 20–69 - NCT04291612Recruiting
Observational study of standard surgery for uterine cancer in women
This is a research study that looks at outcomes in women with endometrial (uterine) cancer who receive the usual standard surgery. Researchers will group patients based on the final surgical and pathology results and what additional (if any) treatment is recommended afterward.
Hartford, ConnecticutAges 18 years+ - NCT02584244RecruitingPhase 1/Phase 2
Testing an imaging scan to find gastrointestinal cancer
This study checks how well the LUM Imaging System can detect cancers of the esophagus, colon, or pancreas during the time you are preparing for surgery. It’s mainly meant to see if the scan works safely and clearly for doctors to find cancer areas.
Boston, MassachusettsAges 18 years+ - NCT04239573Recruiting
Compare pancreatic cyst checkup programs and test markers
This study compares different ways to monitor pancreatic cysts and also measures blood or other test markers to see which approach is more helpful. It may help patients by finding the safest, most effective way to track certain cysts that could otherwise be hard to manage.
Birmingham, AlabamaAges 50–75 - NCT04222413RecruitingPhase 1
Study of metarrestin for advanced solid tumors
This study tests an experimental drug called metarrestin for people with solid tumors that have spread or come back after standard treatment. It may help by targeting a protein involved in cancer cell growth.
Fairway, KansasAges 12–120 - NCT04190758Enrolling by invitation
Early arthritis study for RA, psoriatic arthritis, and psoriasis
This study looks at people with early arthritis related to rheumatoid arthritis, psoriatic arthritis, or psoriasis. Researchers want to understand how these early conditions behave and may help guide better treatment decisions.
GothenburgAges 18–80 - NCT04213547Recruiting
Sleep and blood sugar control in teens with type 2 diabetes
This study looks at how sleep timing and length relate to blood sugar control in teens with type 2 diabetes. It also checks whether teens who meet certain sleep and blood-sugar targets—and can follow sleep tracking—can take part in the study and feedback sessions.
Philadelphia, PennsylvaniaAges 12–20 - NCT04219813Recruiting
Test for gluten peptides in urine for non-celiac gluten sensitivity
This study looks for specific “gluten fragments” (immunogenic peptides) in urine to see if they can detect non-celiac gluten/wheat sensitivity. It may help confirm what’s driving symptoms in people who already avoid gluten.
Palermo, PalermoAges 18–75 - NCT04174755Recruiting
Semaglutide for weight loss in adults with HIV
This trial studies whether semaglutide (a diabetes-type weight-loss injection) helps adults with HIV lose weight. It also checks that it’s safe for people whose HIV is well controlled on regular treatment.
Dublin, DublinAges 18 years+ - NCT04152551RecruitingPhase 4
Bisphosphonate use and hearing loss in type 1 osteogenesis imperfecta
This study looks at whether bisphosphonate treatment affects hearing loss in people with type 1 osteogenesis imperfecta. If you qualify, it may help researchers understand if treatment can protect hearing over time.
New York, New YorkAges 6–100 - NCT04185844Recruiting
Chronic kidney health study for Native American adults
This study follows Native American adults with kidney function changes (either moderately reduced kidney filtration or early urine protein). It aims to better understand kidney disease over time and what factors predict progress, which may help improve care for people like you.
Phoenix, ArizonaAges 21–80 - NCT04205604RecruitingPhase 2
FDOPA PET scan to locate excess insulin in infancy
This Phase 2 study uses an FDOPA PET scan to find where insulin overproduction is coming from in focal congenital hyperinsulinism (FoHI) or related conditions. The goal is to help doctors better detect and localize the “source” so treatment can be more targeted.
San Francisco, CaliforniaAges birth–18 years - NCT04210791Enrolling by invitation
Stem cell transplant using your own cells for AL amyloidosis
This trial tests whether an autologous stem cell transplant (using your own stem cells) can help people with newly diagnosed AL amyloidosis. It may be offered to help your body reset abnormal disease-producing cells, based on your health and test results.
Nanjing, JiangsuAges 18–75 - NCT04204642Recruiting
Testing MRI findings to find markers of brain blood vessel disease
This study looks at brain MRI scans in people with cerebral amyloid angiopathy (a condition where amyloid builds up in brain blood vessels). The goal is to search for “biomarkers,” or measurable scan features, to better understand and detect the disease in some people before symptoms or during symptoms.
Milan, MilanoAges 55 years+ - NCT04194372Recruiting
Health study of risk markers in people with metabolic conditions
This study looks at your health “risk profile” in a hospital group of people with metabolic conditions like diabetes, obesity, or metabolic syndrome. It mainly focuses on measuring factors to better understand who is at higher risk of health problems over time.
Boulogne-sur-MerAges 18 years+ - NCT04210089Recruiting
Soft cast bandage for diabetic foot ulcers
This study tests whether a “total contact” soft cast bandage helps people heal diabetic foot ulcers. You may be asked to get your leg wrapped and have regular follow-up visits so the ulcer can be checked closely.
Minneapolis, MinnesotaAges 18 years+ - NCT04240821Enrolling by invitationPhase 2
Theophylline for pseudohypoparathyroidism after prior study
This Phase 2 trial tests whether the medicine theophylline can help people with pseudohypoparathyroidism. You may be eligible only if you already completed a specific earlier randomized Phase 2 study.
Nashville, TennesseeAges 2–99 - NCT04209816Enrolling by invitation
Genetics study on fatty liver and cholesterol problems
This is a research study testing whether specific gene changes are linked to fatty liver and a cholesterol pattern that raises heart risk. It may help researchers understand who is most likely to develop these conditions and why, which could guide future prevention.
HelsinkiAges 18–70 - NCT04227678Recruiting
Study of how fat is handled after eating in rare LPL deficiency
This study looks at how your body processes fatty acids after meals in people with lipoprotein lipase deficiency (a rare genetic condition). It also compares results to people without the condition, which may help researchers understand metabolism and guide future care.
Sherbrooke, QuebecAges 18–75 - NCT04232566Recruiting
Study links in obesity surgery and liver scarring
This study looks at how the immune system relates to liver scarring in people with obesity who are getting gastric bypass surgery. If you qualify, you may help doctors better understand liver disease and who is at higher risk.
Scottsdale, ArizonaAges 30–70 - NCT04199000Recruiting
Study for congenital glycosylation disorders and NGLY1 deficiency
This trial is for people who have a confirmed genetic condition related to how the body builds certain sugar-like structures (CDG) or NGLY1 deficiency. It aims to better understand these conditions through clinical and basic science research, which may help improve future care.
San Diego, CaliforniaAges Any age
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,640 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 12,087 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.