Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,609 recruiting studies in this area right now.
By phase
- Not applicable5,335
- Phase 2607
- Phase 1560
- Phase 3418
- Phase 4318
- Phase 1/Phase 2287
- Phase 2/Phase 384
Top conditions
- Obesity619
- Ovarian Cancer336
- Pancreatic Cancer287
- Type 2 Diabetes275
- Diabetes192
- Diabetes Mellitus182
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome126
- Obesity & Overweight125
- Breast Cancer111
- Overweight106
- Cardiovascular Diseases105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Endometrial Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Cairo University38
Where studies are running
- California520
- Maryland180
- Alabama176
- Arizona171
- Florida166
- Texas159
- Massachusetts150
- New York143
- Colorado115
- Pennsylvania112
Recruiting studies7,609 total
- NCT04854317Recruiting
Bariatric endoscopy for long-term weight management
This study tests a stomach procedure (endoscopy) to help people with obesity lose weight or control health problems linked to weight. You may be considered if other weight-loss efforts have not worked and surgery is not the best option for you.
OlbiaAges 18–70 - NCT06804694Recruiting
Technology-based support for young adults with type 1 diabetes distress
This study tests a special program that combines technology and a care team to help young adults with type 1 diabetes who feel stressed or overwhelmed by their diabetes. The goal is to see if this approach is helpful and manageable for participants.
Toronto, OntarioAges 18–29 - NCT06752018Recruiting
Inflammation, heart disease, and diabetes study
This study looks at how inflammation affects heart disease and diabetes. It may help find new ways to prevent or treat these conditions.
AarhusAges 18 years+ - NCT06201611RecruitingPhase 2/Phase 3
Nebivolol for diabetic nerve damage study
This study tests whether the drug nebivolol (a type of beta-blocker) can help slow or reverse nerve damage caused by diabetes. It is for people with recent diabetes and confirmed neuropathy.
Bangalore, KarnatakaAges Up to 18 years - NCT06427447RecruitingPhase 3
Chemo with or without radiation after pancreatic cancer surgery
This trial compares adding radiation to chemotherapy versus chemotherapy alone after surgery for pancreatic cancer. It is for people whose cancer had certain high-risk features found during surgery, and who have not yet started additional treatment.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06431867Recruiting
Managing osteoporosis in older women
This study tests a new way for primary care doctors to help older women manage osteoporosis. It aims to find better strategies for treatment and follow-up in the community.
Bradford, West YorkshireAges 70 years+ - NCT07439744Recruiting
Omega-3 for Depression and Obesity
This study tests whether omega-3 fatty acids can improve depression in people with obesity. It looks at how these healthy fats might reduce inflammation and help mood.
Taichung, TaichungAges 18–54 - NCT07435935Recruiting
Vitamin D deficiency and balance study
This study looks at how vitamin D deficiency affects your body's ability to maintain balance and control posture. It may help explain why low vitamin D can impact muscle and bone health.
IstanbulAges 20–40 - NCT07436013Recruiting
Comparing two types of weight-loss revision surgery after sleeve gastrectomy
This trial compares two surgical options for people who have regained weight or didn't lose enough after a sleeve gastrectomy. It tests whether adding a ring to the standard revision surgery helps with long-term weight loss.
Alexandria, Alexandria GovernorateAges 18–65 - NCT07444541RecruitingPhase 1/Phase 2
Study of ANO31905 plus chemo for CLDN18.2-positive pancreatic cancer
This trial tests a new drug called ANO31905 added to standard chemotherapy for people with advanced pancreatic cancer that has a specific protein called CLDN18.2 on its cells. The study aims to see if the combination works better than chemo alone.
Los Angeles, CaliforniaAges 18 years+ - NCT07437911Recruiting
Can a Supplement Help with Nutrient Gaps for GLP-1 Users?
This study tests whether a daily supplement can help fill nutrient gaps and improve gut health for people who are already taking GLP-1 weight-loss medications (like Ozempic or Wegovy). Participants must be on a stable dose for at least 8 weeks and be generally healthy without other chronic conditions.
Santa Monica, CaliforniaAges 18–59 - NCT07438405RecruitingPhase 2
Long-term safety study of AMG 732 for thyroid eye disease
This trial tests the long-term safety and effectiveness of AMG 732 for people with moderate-to-severe thyroid eye disease who have already completed an Amgen study of this drug. It allows continued treatment without needing immediate eye surgery.
Little Rock, ArkansasAges 18–99 - NCT07444593Recruiting
Shin bone transport to heal diabetic foot ulcers
This trial tests whether a surgical technique called transverse tibial bone transport (TTT) can help heal chronic diabetic foot ulcers. TTT involves moving a small piece of the shinbone to encourage new blood vessels to grow to the wound, which may help it close.
Jacksonville, FloridaAges 22 years+ - NCT07443059RecruitingPhase 1
Zovaglutide study in people with kidney problems
This study tests an investigational drug called Zovaglutide (ZT002) in people with different levels of kidney function, from normal to severely impaired. The goal is to see how the drug is processed by the body and how safe it is for people with kidney problems.
Xiamen, FujianAges 18–75 - NCT07442864Recruiting
Study of a supplement for hunger and weight
This trial tests a dietary supplement designed to support leptin, a hormone that helps control appetite. If you're an adult curious about how it affects your hunger and weight, you may be able to join.
New York, New YorkAges 18 years+ - NCT07442006RecruitingPhase 4
Comparing diabetes combos for stable blood sugar
This trial is testing different combinations of diabetes medicines to see which one helps keep your blood sugar more steady throughout the day. It's for people with type 2 diabetes who are already taking metformin and an SGLT-2 inhibitor but still have high blood sugar.
SeoulAges 19 years+ - NCT07440147Recruiting
Akkermansia and Berberine for night shift workers' insulin sensitivity
This trial tests whether taking a probiotic called Akkermansia muciniphila and a natural plant compound called berberine can improve how your body uses insulin. If you work night shifts regularly, this study may help you find a way to support your metabolic health.
Graz, StyriaAges 21 years+ - NCT07437079RecruitingPhase 1
Testing a new weight-loss medicine in healthy people
This study tests a new medicine (NNC6989-0001) for people who are overweight or have obesity. It checks if the medicine is safe and how the body handles it. If eligible, you would receive the study drug and be monitored closely.
Lenexa, KansasAges 18–55 - NCT06806345RecruitingPhase 1/Phase 2
Oxygen therapy for insulin resistance after menopause
This trial tests whether hyperbaric oxygen therapy can help reduce insulin resistance in postmenopausal women. It may offer a new way to improve blood sugar control.
Cairo, Cairo GovernorateAges 55–65 - NCT06806787Recruiting
Can Copeptin and Thirst Predict Weight-Loss Surgery Success?
This study looks at whether levels of a blood marker called copeptin and your sense of thirst can help predict how well bariatric (weight-loss) surgery works. If you are eligible, you will have blood tests and answer questions about thirst before and after surgery.
Bologna, BolognaAges 18–65 - NCT06806917Recruiting
Study on lymph node surgery for testicular cancer over 20 years
This study reviews 20 years of experience in removing lymph nodes in the abdomen (RPLND) for testicular cancer. It aims to understand the outcomes of this surgery for people who had it after chemotherapy or for early-stage cancer.
Bologna, BolognaAges Any age - NCT04705623Recruiting
Iyengar yoga for hot flashes and menopause health
This trial studies whether a structured Iyengar yoga program can improve “bio-functional age” and related health measures in women after menopause. You may help the researchers learn if yoga can reduce menopause symptoms like hot flushes and improve how your body functions.
BernAges 18 years+ - NCT06806813Recruiting
Italian Fabry disease heart registry
This study is creating a registry of people with Fabry disease to better understand how it affects the heart. By joining, you help doctors learn more about the condition and improve care for future patients.
Chieti, Abruzzo/ChietiAges 2 years+ - NCT07440290RecruitingPhase 2/Phase 3
Dabrafenib and trametinib for BRAF V600 cancers
This trial tests two targeted drugs (dabrafenib and trametinib) for patients whose cancer has a specific change in the BRAF gene called V600. These drugs work together to block signals that help the cancer grow. The trial is for children, teenagers, and adults with many types of cancer, except for a few common ones that already have approved treatments.
BelfastAges 1 year+
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,609 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,903 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.