Immunology & allergy
Immune system & allergy clinical trials
Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We’re tracking 6,227 recruiting studies in this area right now.
By phase
- Not applicable3,140
- Phase 21,067
- Phase 1822
- Phase 1/Phase 2446
- Phase 3423
- Phase 4236
- Phase 2/Phase 393
Top conditions
- Multiple Sclerosis342
- Multiple Myeloma333
- Asthma194
- Lymphoma182
- Rheumatoid Arthritis142
- Type 1 Diabetes132
- Atopic Dermatitis128
- Systemic Lupus Erythematosus125
- Acute Lymphoblastic Leukemia123
- HIV Infections116
- Chronic Lymphocytic Leukemia100
- Autoimmune Diseases81
- Follicular Lymphoma74
- Diabetes Mellitus, Type 169
- Hodgkin Lymphoma67
- Leukemia64
- Rheumatoid Arthritis (RA)64
- Acute Myeloid Leukemia62
Leading sponsors
- Institute of Hematology & Blood Diseases Hospital, China91
- National Institute of Allergy and Infectious Diseases (NIAID)90
- National Cancer Institute (NCI)74
- Assistance Publique - Hôpitaux de Paris70
- Novartis Pharmaceuticals65
- M.D. Anderson Cancer Center63
- AstraZeneca57
- City of Hope Medical Center46
- Mayo Clinic46
- Memorial Sloan Kettering Cancer Center45
Where studies are running
- California492
- Maryland196
- Alabama176
- Florida143
- Arizona140
- New York122
- Massachusetts119
- Texas118
- Illinois82
- Colorado77
Recruiting studies6,227 total
- NCT06773546Recruiting
Immune system disorders study for children and adults
This study looks at people with known or suspected inborn errors of immunity (problems with the immune system that you are born with). The goal is to improve how these conditions are diagnosed and managed. If you have immune system issues that started before age 50, you may be able to join.
Bologna, BolgonaAges Up to 50 years - NCT06771440Recruiting
Tool to safely remove antibiotic allergy labels
This trial tests a tool to help doctors safely remove a beta-lactam antibiotic allergy (like penicillin) from your medical record. If you are in the hospital and have such an allergy listed, this tool may help you get the right treatment.
LeuvenAges 18 years+ - NCT07280741RecruitingPhase 4
Shingles vaccine study for people with rheumatic diseases
This study tests the recombinant shingles vaccine in adults with autoimmune rheumatic diseases who are on certain mild medications. It aims to see if the vaccine is safe and effective for them.
São Paulo, São PauloAges 18 years+ - NCT06470191RecruitingPhase 2/Phase 3
B007 for primary membranous nephropathy
This trial tests a new drug called B007 for people with primary membranous nephropathy, a kidney condition. It aims to see if B007 can help reduce protein in the urine and protect kidney function.
BeijingAges 18–80 - NCT06730451Recruiting
Fecal transplant for gut health after organ transplant
This trial tests whether fecal microbiota transplantation (Washed Microbiota Transplantation, or WMT) can help people who have gut problems like diarrhea, constipation, or infection after receiving a solid organ transplant. It aims to restore healthy gut bacteria.
Nanjing, JiangsuAges Any age - NCT06713187Recruiting
Interleukin-23 study in lupus and lung disease
This trial looks at a protein called interleukin-23 in people with lupus, especially those who also have lung inflammation (interstitial lung disease). The goal is to understand more about this protein's role and possibly find new ways to help.
SohagAges 18–60 - NCT06712238Recruiting
Light therapy and methotrexate for psoriasis
This study tests whether combining narrowband UVB light therapy with methotrexate helps treat moderate to severe plaque psoriasis. It looks at a blood marker called gelsolin to see if treatment reduces inflammation.
AswānAges 15–65 - NCT07002203RecruitingPhase 1/Phase 2
Personalized cancer vaccine trial for solid tumors
This trial tests a custom-made vaccine designed to train your immune system to fight your specific cancer. It may be an option if you have advanced cancer that stopped responding to treatment or early-stage cancer with a high risk of coming back.
BangkokAges 20 years+ - NCT07614542Recruiting
Understanding Gut Health and Hormones in Aging Women
This study explores how your gut bacteria and hormones change as you age. Researchers will collect stool and blood samples and ask about your health to better understand women's aging.
LisbonAges 40–64 - NCT06688838Enrolling by invitation
JAK inhibitor for Blau syndrome
This trial tests a new oral drug that blocks inflammation in people with Blau syndrome, a rare genetic condition causing joint, eye, and skin problems. The goal is to see if the drug can reduce symptoms and improve quality of life.
Wuhan, HubeiAges Any age - NCT05930613RecruitingPhase 3
Certolizumab for repeated embryo transfer pregnancy failure
This Phase 3 study tests certolizumab to help people with repeated embryo transfer failures achieve a clinical pregnancy. It may be an option if your infertility has no known cause and you meet the other study checks.
ParisAges 18–40 - NCT05934448RecruitingPhase 2
CAR T plus pembrolizumab for relapsed lymphoma after prior treatment
This Phase 2 trial studies CAR T-cell therapy combined with pembrolizumab for certain hard-to-treat lymphomas that have come back or did not respond. It aims to improve tumor response and outcomes after you’ve already tried standard treatments.
Boston, MassachusettsAges 18 years+ - NCT07433998Recruiting
Ginger drink for inflammation and blood vessel health
This study tests whether a ginger-based drink can reduce inflammation and oxidative stress (a type of cell damage) and improve blood vessel health. It may help adults who are overweight but otherwise healthy.
MurciaAges 23–65 - NCT05946512Recruiting
Yoga breathing plus lung MRI measurements for post-COVID symptoms
This study uses breathing exercises from yoga and MRI (a scan of the body) measurements to see how well yoga breathing can improve ongoing breathing symptoms after COVID-19. It also compares results in a few other specific groups and healthy volunteers.
Innsbruck, TyrolAges 18–50 - NCT07437222Recruiting
Ginger capsules for inflammation in overweight adults
This study tests whether taking ginger capsules can help reduce inflammation, oxidative stress, and improve blood vessel function in people who are overweight or obese but otherwise healthy. You would take ginger capsules daily for several weeks and have your blood and blood vessel health checked.
Murcia, MurciaAges 23–65 - NCT06624839RecruitingPhase 2
HPV vaccine study for people with and without HIV
This study tests how well the Gardasil 9 HPV vaccine works in people assigned male at birth, including those with HIV and those taking hormone therapy. Results could help protect against HPV-related cancers.
Washington D.C., District of ColumbiaAges 18–70 - NCT07653347Recruiting
Infant RSV immunity study
Researchers want to study how infants naturally fight RSV infections. You and your baby may join if your baby is born in April, May, June, September, October, or November at BC Women's Hospital or a nearby hospital.
Vancouver, British ColumbiaAges Up to 6 months - NCT07369739RecruitingPhase 2/Phase 3
Combination therapy for chronic active Epstein-Barr virus disease
This trial tests two drugs, golidocitinib and selinexor, given together to treat chronic active Epstein-Barr virus disease (CAEBVD). The goal is to see if this combination can help control the disease better than current options.
BeijingAges 18–70 - NCT06617962Recruiting
Testing two new blood tests for MOGAD diagnosis
This study is testing two new blood tests to see if they can better diagnose MOGAD, an inflammatory condition that affects the brain and spinal cord. If you or your doctor suspects MOGAD, this trial may help confirm the diagnosis.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06909214RecruitingPhase 4
Study of efgartigimod for new-onset generalized myasthenia gravis
This study tests a new treatment called efgartigimod for people who have been recently diagnosed with generalized myasthenia gravis (gMG). It aims to see if this medicine can help manage symptoms like muscle weakness.
La Jolla, CaliforniaAges 18 years+ - NCT00571389Recruiting
Collecting blood cells from people with cancer or COVID-19
This study collects blood cells using a special blood-draw procedure called leukapheresis (for some participants) and other samples. It aims to better understand cancer and immune-related cells, which may help researchers design or improve future treatments.
Huntersville, North CarolinaAges 5 years+ - NCT07378657RecruitingPhase 3
Sirolimus for children with orbital malformation
This trial tests if sirolimus can help children with a certain type of eye socket malformation. It aims to find a better treatment for children aged 1 to 18.
Cairo, Cairo GovernorateAges 1–18 - NCT04615221Recruiting
Study of immune rejection after uterine transplant
This study looks at why the body’s immune system may reject a transplanted uterus or a related surgery. Your results may help doctors understand rejection and improve care for future uterine transplants.
SuresnesAges 18–45 - NCT06697665RecruitingEarly Phase 1
LM103 vaccine with PD-1 for advanced solid tumors
This trial tests a new personalized cancer vaccine (LM103) combined with an immunotherapy drug (PD-1) for people with advanced solid tumors that have stopped responding to standard treatments. The goal is to see if this combination is safe and can help shrink tumors.
China, Tianjin MunicipalityAges 18–75
Common questions
- How many immune system & allergy clinical trials are recruiting?
- Clin2 is tracking 6,227 recruiting immunology & allergy studies from the U.S. registry right now, out of 9,696 we cover in this area in total.
- What does “Immune system & allergy” cover here?
- Autoimmune conditions, allergies, and disorders of the body’s immune defenses. We group each study into immune system & allergy based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a immune system & allergy trial near me?
- Use the search to filter immune system & allergy studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.