Infectious disease
Infections clinical trials
Bacterial, viral, and other infections — from common illnesses to emerging threats. We’re tracking 3,966 recruiting studies in this area right now.
By phase
- Not applicable2,544
- Phase 2357
- Phase 4302
- Phase 1287
- Phase 3286
- Phase 1/Phase 2131
- Phase 2/Phase 359
Top conditions
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)89
- Assistance Publique - Hôpitaux de Paris69
- University of California, San Francisco39
- Johns Hopkins University30
- National Cancer Institute (NCI)28
- Hospices Civils de Lyon27
- Columbia University24
- University of Washington23
- University of Alabama at Birmingham22
- University of Oxford22
Where studies are running
- California234
- Maryland142
- Alabama92
- New York73
- Florida72
- Texas63
- Massachusetts55
- Arizona48
- Pennsylvania44
- Illinois41
Recruiting studies3,966 total
- NCT05504057Recruiting
Testing antihistamines and amantadine for COVID-19
This study looks at how ongoing antihistamines or amantadine treatment affects the course of COVID-19. If you already take one of these medicines regularly, the study may help understand whether it offers any benefit.
Terrassa, BarcelonaAges Any age - NCT05474430Recruiting
Study testing how common lung infections relate to CF gene status
This study looks at whether carrying one CF gene (being a “CF carrier”) changes the risk of getting respiratory infections. It may help researchers understand how genetics can affect lung health, even for people who do not have cystic fibrosis.
Iowa City, IowaAges 18–100 - NCT05471973Recruiting
Study for suspected heart device infection care improvement
This study is testing an approach to improve how clinicians care for people with suspected infections around an implanted heart device (like a pacemaker or defibrillator). It may help ensure the infection is recognized and treated appropriately, especially when device removal (extraction) might be needed.
Chicago, IllinoisAges 18 years+ - NCT05488431RecruitingPhase 2
Bempedoic acid to lower cholesterol and inflammation in HIV
This Phase 2 trial studies whether bempedoic acid can lower cholesterol and inflammation in people with HIV who are already on effective HIV medications. It may help reduce signs of artery inflammation that can contribute to heart and stroke risk.
Los Angeles, CaliforniaAges 40 years+ - NCT05473520RecruitingPhase 3
Doxycycline add-on therapy for lung improvement in tuberculosis
This Phase 3 trial tests whether adding doxycycline to standard TB medicine can improve lung function and reduce lung tissue damage. It aims to see if patients recover better by targeting the lung response to TB.
Kota Kinabalu, SabahAges 21 years+ - NCT05475574Recruiting
Stopping extra cleaning for some resistant bacteria in geriatrics
This trial looks at whether stopping extra “contact precautions” (special measures to prevent spread) is safe for older hospital patients who carry a certain type of hard-to-treat gut bacteria. It may reduce unnecessary isolation and improve comfort, while still aiming to prevent infections.
MetzAges 65 years+ - NCT05464251Recruiting
Review study for spinal infection diagnosis and outcomes
This study reviews medical records of people with certain spine infections, including infections of the spine bones, the discs, and the space around the spinal cord. It may help doctors better understand these conditions and how they are diagnosed and followed over time.
Lexington, KentuckyAges 18 years+ - NCT05470023Recruiting
Imaging study of gum health and mouth biofilm
This study uses imaging to look at how healthy your gums are and how much “plaque/biofilm” is in your mouth. It may help researchers better understand gum health and how oral hygiene affects it.
Irvine, CaliforniaAges 18 years+ - NCT05480449RecruitingPhase 1/Phase 2
Personalized CAR-T for children with high-risk B-ALL
This trial studies a personalized type of immune therapy (CAR-T) made from your own cells to treat pediatric B-ALL that has returned or not responded to prior treatment. It aims to see how well this manufactured CAR-T works and how safely it can be given.
Philadelphia, PennsylvaniaAges birth–29 years - NCT05492565Enrolling by invitation
Follow-up study for people on HIV prevention pills
This study follows adults who are at high risk of getting HIV while they take HIV prevention pills (PrEP). It aims to learn how well PrEP fits real-life use in people at risk and who may need extra care.
Seville, AndalusiaAges 18 years+ - NCT05466071Recruiting
TAF to prevent hepatitis B transmission during pregnancy
This study tests whether a daily antiviral pill called TAF can reduce the risk of passing hepatitis B to your baby. It is for pregnant women with high levels of the virus who are between 24 and 28 weeks along.
Guangzhou, GuangdongAges 20–40 - NCT05471479RecruitingPhase 4
Activated charcoal for recent poisoning in hospital patients
This pilot study tests giving activated charcoal soon after a poisoning to see if it helps remove certain swallowed toxins. It may be an option if you arrive at the hospital within 6 hours and charcoal is medically safe for you.
Québec, QuebecAges Any age - NCT05496036RecruitingPhase 2
Pembrolizumab before surgery for resectable Merkel cell cancer
This trial tests pembrolizumab (an immune therapy) given before surgery to shrink Merkel cell carcinoma and improve outcomes. Participants also have extra tumor biopsies to study biomarkers, which may help explain who benefits most.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04288674Recruiting
Leptospirosis patient registry study in hospitals
This study records information from people who have invasive (spreading) leptospirosis, a bacterial infection. The goal is to better understand how the disease presents and spreads, which can help improve future care.
Cologne, North Rhine-WestphaliaAges Any age - NCT04323904Recruiting
Hantavirus registry for people with kidney or lung symptoms
This study is a registry, meaning it collects health information and possibly test results from people who have evidence of hantavirus infection along with specific illness symptoms. It may help researchers better understand how hantavirus affects the kidneys or the heart/lungs (and how to recognize it).
Cologne, North-Rhine WestfaliaAges Any age - NCT04392401Recruiting
Study immune changes in adults during ICU stay for COVID-19
This study looks at how your immune system responds while you’re in the intensive care unit (ICU) for COVID-19. Researchers will collect samples early in the ICU stay to better understand immune changes during the illness.
BronAges 18 years+ - NCT05384132Recruiting
Dental gel trial with deep cleaning for gum disease
This study tests whether a new dental gel used along with deep gum cleaning (scaling and root planing) can improve periodontitis. If you qualify, you would receive standard gum treatment plus the study gel, then be followed over time.
Birmingham, AlabamaAges 18–85 - NCT05166850Recruiting
Preventive cholera help for households for 7 days
This study tests a 7-day preventive intervention for cholera-like diarrhea in households without running water. It may help reduce illness spread and protect young children when families lack safe water at home.
Bukavu, South KivuAges Any age - NCT05442515RecruitingPhase 1/Phase 2
CAR T-cell treatment for hard-to-treat B-cell cancers in youth
This trial tests a personalized immune-cell therapy (CAR T cells) made to attack B-cell cancers that have come back or did not respond to prior treatment. It aims to see how well the treatment works and how safe it is in children and young adults.
Bethesda, MarylandAges 3–39 - NCT05419024RecruitingPhase 2
Imaging and biopsy during a planned HIV treatment pause
This Phase 2 study uses special scans (PET/CT) and tissue sampling (biopsy) to learn what is happening in the body while people with HIV take a planned break from antiretroviral therapy (ART) for up to 90 days. It may help researchers find better ways to control HIV without ongoing treatment, though joining involves careful monitoring during the pause.
Bethesda, MarylandAges 18–100 - NCT05421858RecruitingPhase 3
Study drug for adults with bloodstream or deep Candida infection
This Phase 3 trial tests fosmanogepix to treat adults with candidemia (Candida in the bloodstream) and/or invasive candidiasis (a deep Candida infection). It looks at whether the medicine is effective and safe, and whether it helps the infection improve when doctors also manage the infection source.
Birmingham, AlabamaAges 18 years+ - NCT05418868RecruitingPhase 1
Long-acting cabotegravir injection safety in healthy adults
This Phase 1 study tests how the body handles a long-acting (slow-release) cabotegravir injection combined with a drug called hyaluronidase. It also checks safety and side effects in healthy adults to help future HIV-prevention or treatment plans.
Orlando, FloridaAges 18–55 - NCT05452941Recruiting
Pneumonia vaccine study for hospitalized adults 65 and older
This study tests a pneumococcal vaccine designed for 20 types of bacteria in older adults who are hospitalized with suspected community-acquired pneumonia. It aims to see how the vaccine works in real-world care and whether it affects how pneumonia happens or progresses.
El Centro, CaliforniaAges 65 years+ - NCT05415267RecruitingPhase 3
Boosting COVID protection during long-term immune suppression
This study looks at how well a COVID-19 booster works in adults who need long-term medicines that lower immune response. It aims to see whether immunosuppressed people benefit from booster vaccination safely.
Blacktown, New South WalesAges 18 years+
Common questions
- How many infections clinical trials are recruiting?
- Clin2 is tracking 3,966 recruiting infectious disease studies from the U.S. registry right now, out of 6,624 we cover in this area in total.
- What does “Infections” cover here?
- Bacterial, viral, and other infections — from common illnesses to emerging threats. We group each study into infections based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a infections trial near me?
- Use the search to filter infections studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.