Infectious disease
Infections clinical trials
Bacterial, viral, and other infections — from common illnesses to emerging threats. We’re tracking 4,173 recruiting studies in this area right now.
By phase
- Not applicable2,709
- Phase 2360
- Phase 4322
- Phase 1292
- Phase 3284
- Phase 1/Phase 2141
- Phase 2/Phase 365
Top conditions
Leading sponsors
- National Institute of Allergy and Infectious Diseases (NIAID)89
- Assistance Publique - Hôpitaux de Paris80
- University of California, San Francisco44
- Johns Hopkins University32
- Hospices Civils de Lyon30
- National Cancer Institute (NCI)28
- University of Washington27
- University Hospital, Strasbourg, France26
- Columbia University23
- University of Alabama at Birmingham23
Where studies are running
- California235
- Maryland147
- Alabama89
- New York77
- Florida74
- Texas61
- Massachusetts56
- Arizona46
- Pennsylvania45
- Illinois42
Recruiting studies4,173 total
- NCT04690972Recruiting
Collection of blood and tissue samples for liver disease research
This study builds a research library of biological samples (like tissue and blood) from people with chronic liver disease. It aims to create better lab and preclinical models of tumors and long-term liver problems, which may help future treatments.
StrasbourgAges 18 years+ - NCT04691622RecruitingPhase 1
Treat chronic norovirus using donor immune cells
This Phase 1 study tests whether giving immune cells made from a donor can help children and adults with long-lasting (chronic) norovirus infection. It’s aimed at people whose immune system is weakened after a stem cell transplant, solid organ transplant, or due to primary immune problems.
Washington D.C., District of ColumbiaAges 3 months–80 years - NCT04700579Recruiting
Study lung changes before and after treatment for active TB
This study looks at changes in the lungs and immune system before TB treatment and again after treatment. By sampling lung fluid and comparing it over time, researchers hope to learn signatures that reflect how TB responds to care.
Cape Town, Western CapeAges 18–60 - NCT04705766Recruiting
Study kidney injury after recent COVID infection
This study looks at how COVID can affect the kidneys soon after infection. You may be able to participate if you recently tested positive for COVID and have not had kidney replacement treatments.
San Francisco, CaliforniaAges 18 years+ - NCT04706390Recruiting
Study compares immune response after COVID infection vs vaccination
This study looks at how your immune system responds after natural COVID-19 infection compared with after COVID vaccination. It may help researchers understand how well different experiences train the body’s defenses.
BergenAges 20–100 - NCT04712539RecruitingPhase 2
Baloxavir and oseltamivir for severe flu in immune-compromised people
This trial tests whether two flu medicines—baloxavir and oseltamivir—work better to treat influenza in people with weakened immune systems (like transplant or blood cancer patients). It may help reduce severe complications, especially when flu affects the lungs or is at high risk to do so.
Houston, TexasAges 12 years+ - NCT04722029RecruitingPhase 1/Phase 2
Donor immune-cell therapy for stubborn adenovirus infections
This study tests whether specially matched donor T-cells can control “refractory” adenovirus (a virus) that isn’t responding to usual antiviral medicines. It may help if the infection keeps coming back or is already affecting organs like the lungs or bowel.
Columbus, OhioAges Up to 60 years - NCT04721717Recruiting
Workshop for healing writing after paralysis
This trial tests whether a structured writing workshop can help people living with paralysis and their ALS caregivers. It focuses on communication through words (spoken or written) to support well-being.
Birmingham, AlabamaAges 18 years+ - NCT04725916Recruiting
Study of water exposure and drain-related risks after certain surgeries
This trial looks at how using water (like showers) affects risks related to surgical drains after specific cosmetic or reconstructive procedures. Your results may help improve post-surgery safety guidance for patients who go home with drains.
Danville, PennsylvaniaAges 18 years+ - NCT04735835Recruiting
Personalized diet testing using ZOE app and blood samples
This trial studies how different food compositions affect your body, using the ZOE testing program plus meals you eat and blood samples you collect. It may help you learn more about what foods work best for you, especially if you have a long-term health condition.
Needham, MassachusettsAges 18 years+ - NCT04736732Recruiting
Post-COVID research clinic for adults in Quebec
This study invites adults in Quebec to complete questionnaires and possibly follow-up checks about past COVID-19 infection or symptoms. It may help researchers better understand ongoing effects after COVID, or compare people with different COVID test histories.
Montreal, QuebecAges 18–100 - NCT04743609Recruiting
Studying RSV illness impact in babies with ear or lung symptoms
This study looks at how RSV (a common virus that can affect breathing) leads to illness in young children who come to the doctor with ear infections and/or breathing symptoms. It may help doctors better understand the “burden” RSV causes in both home/outpatient and hospital settings.
CréteilAges 1 day–2 years - NCT04745403RecruitingPhase 1
Trial of redirected HBV-targeting T cells for liver cancer
This Phase 1 study tests a lab-made immune cell treatment that targets hepatitis B (HBV)–related liver cancer. It may help by directing the body’s immune system to attack the cancer, while carefully checking safety.
SingaporeAges 21–75 - NCT04746183RecruitingPhase 1/Phase 2
Early trial testing treatments for COVID-19 in the first days
This early-stage study tests COVID-19 treatments in people who have recently developed symptoms and who test positive for the virus. It aims to find safer, more effective options for preventing worsening disease, especially in higher-risk groups.
Cape TownAges 18 years+ - NCT04746209RecruitingPhase 2
Blinatumomab after transplant for high-risk B-ALL patients
This trial tests blinatumomab, an immune therapy, in young people with B-cell acute lymphoblastic leukemia (B-ALL) after their transplant or when they are getting ready for transplant. The goal is to lower the chance of the leukemia coming back by targeting remaining leukemia cells.
Milwaukee, WisconsinAges Up to 25 years - NCT04748796RecruitingPhase 3
Landiolol to prevent death in ventilated septic shock patients
This trial tests whether landiolol (a short-acting heart-rate–lowering medicine) can reduce deaths compared with standard care in people in septic shock who have a fast heart rate and strong heart pumping. It is meant for a very specific type of critically ill patient while they are on a breathing machine.
AmiensAges 18 years+ - NCT04750070RecruitingPhase 3
Treating shock in young children with severe malnutrition and diarrhea
This study tests a treatment approach to help children who are in “shock” (their body is struggling to maintain blood flow and oxygen) caused by diarrhea and severe undernutrition. It may help care teams stabilize children faster and improve outcomes.
DhakaAges 1 month–4.9 years - NCT04751396Recruiting
Melanoma education for people with autoimmune conditions
This trial tests an educational tool to help people with melanoma and pre-existing autoimmune disease understand immune checkpoint inhibitor treatment. It aims to support you and your care team with information that can help you make decisions and feel more prepared.
Houston, TexasAges 18 years+ - NCT04759001RecruitingPhase 1/Phase 2
Fecal treatment to clear gut bacteria resistant to antibiotics
This study tests a stool-based treatment (fecal microbiota treatment) to help remove “carbapenem-resistant” bacteria living in the gut. If you carry these bacteria without being sick, the goal is to reduce or stop that colonization.
RomeAges 18–90 - NCT04762134Recruiting
Doxycycline to prevent future bacterial STIs in high-risk men
This trial tests whether taking doxycycline can lower the chance of getting bacterial sexually transmitted infections like syphilis, gonorrhea, and chlamydia. It is aimed at men who have had these infections recently and expect to keep having multiple male partners.
Calgary, AlbertaAges 18 years+ - NCT04767945Recruiting
Cirrhosis patient hospital registry
This study keeps a record of people who have liver cirrhosis and were admitted to the hospital after a worsening event. It may help doctors better understand what leads to hospital stays and improve future care.
Banská BystricaAges 19 years+ - NCT04771728RecruitingPhase 4
Probiotics added to treatment for bacterial vaginosis
This study tests whether adding probiotics to standard care helps treat bacterial vaginosis (BV) and possibly lowers the chance of it coming back. You would be placed into a study group to compare probiotic treatment with the other approach.
Shenzhen, GuangdongAges 18–55 - NCT04772170Recruiting
Study wearable and symptom monitoring during respiratory virus challenges
This observational study looks for digital health patterns during studies where people are intentionally exposed to a respiratory virus. If you join a respiratory virus challenge at NIH, you may help researchers discover better ways to monitor and understand illness using wearable devices and shared health data.
Bethesda, MarylandAges 18–65 - NCT04774705Recruiting
Noninvasive vagus nerve stimulation for sepsis in the ICU
This study tests whether a noninvasive device that stimulates the vagus nerve can help adults with sepsis in the intensive care unit. Researchers want to see if adding this treatment improves outcomes compared with standard ICU care.
GarchesAges 18 years+
Common questions
- How many infections clinical trials are recruiting?
- Clin2 is tracking 4,173 recruiting infectious disease studies from the U.S. registry right now, out of 7,061 we cover in this area in total.
- What does “Infections” cover here?
- Bacterial, viral, and other infections — from common illnesses to emerging threats. We group each study into infections based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a infections trial near me?
- Use the search to filter infections studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.