Trauma
Injuries & trauma clinical trials
Wounds, fractures, and recovery from physical injury. We’re tracking 3,016 recruiting studies in this area right now.
By phase
- Not applicable2,561
- Phase 2123
- Phase 4112
- Phase 382
- Phase 182
- Phase 1/Phase 234
- Phase 2/Phase 322
Top conditions
- Traumatic Brain Injury151
- Spinal Cord Injuries142
- Spinal Cord Injury105
- Stroke64
- Trauma51
- Mild Traumatic Brain Injury40
- Amputation38
- Anterior Cruciate Ligament Injuries37
- Radiotherapy Side Effect37
- Hip Fractures36
- Rotator Cuff Tears35
- Spinal Cord Injuries (SCI)34
- Burns28
- Carpal Tunnel Syndrome28
- Anterior Cruciate Ligament Rupture27
- Cardiotoxicity26
- Carpal Tunnel Syndrome (CTS)26
- Breast Cancer25
Leading sponsors
- VA Office of Research and Development34
- Cairo University22
- Kessler Foundation20
- Johns Hopkins University19
- University of Miami19
- Zimmer Biomet19
- University of Florida18
- University of British Columbia17
- Mayo Clinic16
- Riphah International University16
Where studies are running
- California159
- Texas91
- Florida79
- New York78
- Illinois57
- Massachusetts55
- Pennsylvania51
- Minnesota45
- Ohio43
- Colorado41
Recruiting studies3,016 total
- NCT05644171Recruiting
Epidural spinal stimulation for chronic spinal cord injury recovery
This trial tests whether a stimulating device placed near the spinal cord can help improve movement and rehabilitative function in people with long-term spinal cord injuries. It may help some patients strengthen function, but only if they meet specific injury and health requirements.
SingaporeAges 21 years+ - NCT05663034Recruiting
Compare CBT-I vs MBTI for sleep and trauma symptoms after TBI
This study compares two types of talk-based therapy to help veterans with long-lasting insomnia after a traumatic brain injury (TBI), and also looks at related post-trauma stress symptoms. It may help you improve sleep and reduce how much these symptoms affect daily life.
Eglin Air Force Base, FloridaAges 18 years+ - NCT05637294Recruiting
Compare night-only versus full-time splinting for carpal tunnel
This study looks at whether wearing a wrist splint only at night works as well as wearing it full-time for carpal tunnel syndrome (CTS). It may help you find the most helpful and practical splint schedule to reduce symptoms.
HelsinkiAges 18 years+ - NCT05668182Recruiting
TRUMATCH graft cage for broken thigh/leg/arm bone gaps
This study looks at how well a specific metal implant (the TRUMATCH graft cage) works when there is a missing segment of a long bone in the arm, thigh, or shin. It may help stabilize the bone while doctors rebuild the defect with standard surgical care.
San Diego, CaliforniaAges 18 years+ - NCT05673551Enrolling by invitation
VR during at-home burn dressing changes for kids
This trial tests whether virtual reality (VR) can help children feel better during daily burn dressing changes at home. It will study comfort and pain around the first time you do dressings after leaving the hospital.
Columbus, OhioAges 6–17 - NCT05670288Recruiting
Studying how gut bacteria affect digestion after spinal cord injury
This study looks at how changes in gut bacteria may affect bowel function and metabolism during the first year after a spinal cord injury. You may be asked about bowel symptoms and other factors, and your results may help guide future care for digestion problems after injury.
Birmingham, AlabamaAges 18–85 - NCT05645003Recruiting
Brain stimulation therapy for nerve pain after spinal cord injury
This trial tests whether painless magnetic stimulation of the brain (non-surgical) can reduce long-lasting nerve pain after spinal cord injury. It may help people whose spinal cord injury-related pain has been present for at least six months.
AfyonkarahisarAges 20–70 - NCT05601869Recruiting
Testing better footwear options for women with below-knee amputations
This study looks at whether improving what you can use for your prosthesis and footwear can improve comfort, balance, and daily activities. It focuses on women Veterans with below-knee (transtibial) amputations who already use a well-fitting prosthesis.
Minneapolis, MinnesotaAges 18–89 - NCT05619588Recruiting
Long-term follow-up for a new ankle replacement (U.S. only)
This study checks how well an Exactech total ankle replacement works over many years. You may be asked to complete follow-up forms for up to 10 years to help track safety and outcomes.
Jacksonville, FloridaAges 21 years+ - NCT05603728Recruiting
Follow-up study for Exactech shoulder implants after surgery
This study follows people who get (or already had) a shoulder replacement to see how the implant is doing over time. It may help improve future care by tracking long-term performance and safety.
Laguna Woods, CaliforniaAges 21 years+ - NCT05635929Recruiting
Topical treatment to reduce mouth sores during or after radiation
This study tests a new cream/gel applied to the mouth to lower the chance of severe mouth sores in people receiving radiation for head and neck cancer. It also looks at how treatment affects quality of life using patient questionnaires.
Madrid, MadridAges 18 years+ - NCT05616312Recruiting
Study of how patients remember orthopedic injury care
This study looks at how well patients recall details after a bone fracture that required surgery, especially around the time of their injury care and follow-up. It may help improve how orthopedic teams communicate and support patients after trauma.
Cleveland, OhioAges 18–75 - NCT05596539Recruiting
Study of adults with low alkaline phosphatase
This is a long-term observational study (not a drug trial) that follows adults with signs of hypophosphatasia, a condition linked to very low alkaline phosphatase levels and sometimes a gene change. It aims to better understand the condition over time and how symptoms look and progress.
Bordeaux, FranceAges 18 years+ - NCT05598879Recruiting
New heart-cancer visit registry for adults
This study is a “registry,” meaning it collects health information from adults who are getting a new heart (cardio) evaluation related to cancer. It helps doctors better understand heart risks and care needs for different cancer types and treatments.
Weston, FloridaAges 18 years+ - NCT05612828Enrolling by invitation
Testing training mannequins for military medics
This study tests whether using simulation mannequins improves training for military medics during a lifesaving first-aid course. You may be considered if you’re actively enrolled in this training and willing to join the study.
KladnoAges Any age - NCT05616130Recruiting
Study of abnormal blood immune activation after trauma or elective hip surgery
This study looks at how the body’s blood-related immune system “switches on” in unusual ways after a major injury or elective hip repair. The researchers hope this helps them understand who is at risk for complications and why, by measuring changes in your blood around the time of surgery or hospital treatment.
Gainesville, FloridaAges 18–100 - NCT05600868Enrolling by invitation
Testing dual attention during EMDR therapy for PTSD
This study tests whether adding “dual attention” to EMDR therapy helps people with high PTSD symptoms. If you have significant PTSD symptoms, this approach may improve how well the therapy works, but it depends on safety and recent treatment history.
Pozuelo de Alarcón, MadridAges 18–65 - NCT05616910Enrolling by invitationPhase 2
Inhaled nitric oxide for microvascular problems after brain injury
This Phase 2 study tests whether inhaled nitric oxide can improve tiny blood-flow problems in the brain after traumatic brain injury. If you qualify, you may receive inhaled nitric oxide and be monitored for safety and recovery.
Philadelphia, PennsylvaniaAges 18–75 - NCT05619822Enrolling by invitation
Third-steps therapy for psychosis and PTSD symptoms
This study tests a structured therapy program for people who have both psychosis symptoms and high PTSD symptoms. It aims to reduce distress from past trauma while also supporting mental health symptoms.
Pozuelo de Alarcón, MadridAges 18–65 - NCT05614908Enrolling by invitation
Testing outcomes after non-surgical Achilles tendon rupture care
This trial looks at how well people do after an Achilles tendon rupture when they are treated without surgery. It may help improve recovery guidance for others by comparing outcomes based on how care is followed.
AarhusAges 18 years+ - NCT05626816Recruiting
Genital nerve stimulation to improve bowel control after spinal injury
This trial studies whether stimulating nerves near the genitals (a gentle electrical stimulation approach) can improve bowel function in people with spinal cord injury. It may help bowel control when bowel dysfunction is caused by nerve injury.
Cleveland, OhioAges 18 years+ - NCT05615844RecruitingPhase 3
Antibiotic beads versus negative pressure dressing for severe leg fractures
This Phase 3 study compares two ways to help heal a severe open tibia (shin bone) fracture and prevent complications like infection. If you qualify, you may receive antibiotic beads or a negative pressure wound therapy dressing after urgent wound cleaning.
Chandler, ArizonaAges 18 years+ - NCT05627908Recruiting
PseAn study for adults with certain organ injuries
This trial is for adults who have had a CT-confirmed injury to the spleen, liver, and/or kidney from blunt or penetrating trauma. The goal is to study this type of injury and compare how patients do after treatment.
Milan, ItaliaAges 18 years+ - NCT05613972Recruiting
Combined therapy for adults with suicidal thoughts and childhood trauma
This study tests a new combination of talk therapies for adults who have both suicidal thoughts and a history of childhood trauma. The goal is to see if this combined approach reduces suicide risk better than usual care.
Toronto, OntarioAges 18 years+
Common questions
- How many injuries & trauma clinical trials are recruiting?
- Clin2 is tracking 3,016 recruiting trauma studies from the U.S. registry right now, out of 4,936 we cover in this area in total.
- What does “Injuries & trauma” cover here?
- Wounds, fractures, and recovery from physical injury. We group each study into injuries & trauma based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a injuries & trauma trial near me?
- Use the search to filter injuries & trauma studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.