Trauma
Injuries & trauma clinical trials
Wounds, fractures, and recovery from physical injury. We’re tracking 3,016 recruiting studies in this area right now.
By phase
- Not applicable2,561
- Phase 2123
- Phase 4112
- Phase 382
- Phase 182
- Phase 1/Phase 234
- Phase 2/Phase 322
Top conditions
- Traumatic Brain Injury151
- Spinal Cord Injuries142
- Spinal Cord Injury105
- Stroke64
- Trauma51
- Mild Traumatic Brain Injury40
- Amputation38
- Anterior Cruciate Ligament Injuries37
- Radiotherapy Side Effect37
- Hip Fractures36
- Rotator Cuff Tears35
- Spinal Cord Injuries (SCI)34
- Burns28
- Carpal Tunnel Syndrome28
- Anterior Cruciate Ligament Rupture27
- Cardiotoxicity26
- Carpal Tunnel Syndrome (CTS)26
- Breast Cancer25
Leading sponsors
- VA Office of Research and Development34
- Cairo University22
- Kessler Foundation20
- Johns Hopkins University19
- University of Miami19
- Zimmer Biomet19
- University of Florida18
- University of British Columbia17
- Mayo Clinic16
- Riphah International University16
Where studies are running
- California159
- Texas91
- Florida79
- New York78
- Illinois57
- Massachusetts55
- Pennsylvania51
- Minnesota45
- Ohio43
- Colorado41
Recruiting studies3,016 total
- NCT01166893Recruiting
Imaging tests to measure burn healing and severity
This trial uses special imaging methods, including a laser-based technique, to judge how severe a burn wound is and how likely it is to heal. The goal is to see whether these scans can help doctors track burn healing more accurately.
Orange, CaliforniaAges 1 minute+ - NCT03024008RecruitingPhase 1/Phase 2
Study of bone-healing paste from your own cells for broken bones
This trial tests a bone-healing product made from your own tissue (“autologous BonoFill-II”) to help heal difficult fractures or bone gaps that aren’t healing on their own. It’s designed for people who have a serious bone injury in an arm or leg that needs stronger support to regenerate.
AfulaAges 18–80 - NCT05553353Recruiting
Repeated brain stimulation for depression after spinal cord injury
This study tests a non-drug treatment called repeated transcranial magnetic stimulation (rTMS) to reduce depression symptoms in people with depression after a spinal cord injury. You might be eligible if you have ongoing major depression and can safely receive magnetic pulses to the head.
Charleston, South CarolinaAges 18–60 - NCT05563103Recruiting
Combination therapy to improve spinal cord injury recovery
This trial studies a combination of treatments to help people with certain types of spinal cord injury regain some movement and feeling over time. If you meet the specific injury and health criteria, you may be asked to do simple walking and assessment tests during treatment.
Chicago, IllinoisAges 18–70 - NCT05589701Recruiting
Compare two radiation plans for painful spinal cancer spread
This study compares two different radiation approaches—SBRT and CRT—for people with painful cancer that has spread to the spine. It may help determine which plan controls pain and tumor growth while limiting side effects to nearby organs.
Toronto, OntarioAges 18–100 - NCT05588115Recruiting
Test blood biomarkers to help diagnose concussion
This study checks whether a blood test can accurately and quickly identify an uncomplicated concussion. It may help doctors confirm concussion sooner and more reliably, and potentially reduce time and cost of diagnosis.
Calgary, AlbertaAges 18–65 - NCT05553457Recruiting
Active hand brace study for C6–C7 spinal cord injury
This trial tests an active hand brace designed to help people with C6–C7 spinal cord injury improve hand and finger movement. It may help with daily hand use by training and supporting weaker motor control after injury.
New York, New YorkAges 18 years+ - NCT05590494Recruiting
New treatment for partial rotator cuff shoulder tears
This trial tests a new approach for people with a partial (not full) tear of the rotator cuff, found on MRI. It may help improve shoulder function if your tear matches the study’s specific size and location rules.
Onalaska, WisconsinAges 25–75 - NCT05564494Recruiting
Surgery for repeat shoulder dislocations
This trial studies surgical treatment for people whose shoulder keeps dislocating forward (anteriorly). It may help by choosing a surgery plan for the amount of bone loss seen on scans, while excluding people with certain medical or instability patterns.
New York, New YorkAges 16–40 - NCT05584020Recruiting
ACL repair vs. reconstruction for a recent tear
This study compares two ways to repair a torn ACL: stitching it back together (repair) versus using a graft from another tendon (reconstruction). It is for people who have a fresh, uncomplicated ACL tear and want to see which approach works better.
Hangzhou, ZhejiangAges 18 years+ - NCT05555459Recruiting
Testing a screw system for foot and ankle surgery
This study checks how safe and well an “Inion CompressOn” screw system works during foot and ankle operations. It may help patients by improving how surgeons fix bones while also collecting safety and recovery information.
TampereAges 18 years+ - NCT05587244Enrolling by invitation
Hip liner study for people getting a hip replacement
This study looks at a specific type of hip replacement liner (the part inside the hip joint) and how well it works after surgery. You might be eligible if you’re planning a one-sided hip replacement and don’t have certain infection, bone, or health problems that could affect healing.
Birmingham, AlabamaAges 18–80 - NCT05583448Enrolling by invitation
Study of a radial head elbow implant after elbow surgery
This trial follows people who already received a specific radial head elbow implant (Explor Radial Head System) to see how it performs over time. It may help improve care for elbow problems like arthritis or injuries that caused pain and limited movement.
Louisville, KentuckyAges 18 years+ - NCT05183074Recruiting
MRI-guided focused radiation for prostate cancer
This trial tests a newer way to plan and deliver radiation for prostate cancer using real-time MRI guidance. It may help by aiming high-dose treatment precisely while treating nearby disease and (in some cases) limited metastatic spots.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05224934Recruiting
Radiation before surgery for retroperitoneal soft-tissue sarcoma
This trial tests giving a shorter, lower-dose radiation treatment before surgery for a retroperitoneal (deep belly/back space) soft-tissue sarcoma. The goal is to shrink or control the tumor and make surgery more effective and safe.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05536609Recruiting
Suture method comparison for injured finger nerves
This study compares two surgical techniques to repair an injured nerve in the finger. It aims to improve how well sensation comes back after a traumatic digital nerve injury.
Stockholm, Stockholm CountyAges 20 years+ - NCT04610697Recruiting
Cognitive training for people in forensic mental health care
This trial studies whether a structured “cognitive remediation” program (training thinking skills) can help people receiving care on a forensic treatment unit. It may benefit those who want support improving attention, memory, or problem-solving as part of their treatment.
Ottawa, OntarioAges 18–55 - NCT05527041Enrolling by invitation
Portable eye test device for mild concussion after injury
This study tests a portable device that uses eye checks to assess people with a mild concussion after a head or body impact. It may help find concussion-related changes in settings like deployment or far-forward locations.
West Point, New YorkAges 17–35 - NCT05548972Enrolling by invitation
Follow-up study of a hip replacement to improve implant wear
This study checks how well a specific hip replacement bearing surface (called dual mobility with Vivacit-E or Longevity) performs over time in real-world patients. It may help people by tracking long-term safety and performance to guide better hip replacement choices.
Little Rock, ArkansasAges 18–80 - NCT05521958Enrolling by invitation
Gene activity study in severe leg muscle swelling after fracture
This study looks at gene activity (what genes are “turned on or off”) in the lower leg in people with acute compartment syndrome after a tibia (shin bone) injury. The goal is to better understand what is happening in the body and potentially guide future treatment decisions.
Salt Lake City, UtahAges 18–90 - NCT05514405Recruiting
Testing two anesthesia medicines to prevent confusion after surgery
This trial tests whether using remimazolam or propofol during hip or knee replacement surgery can lower the risk of postoperative delirium, a sudden, short-term confusion that can happen after anesthesia. It may help people who are at higher risk of postoperative confusion by finding the safer anesthesia approach.
SeoulAges 65–100 - NCT05541250RecruitingPhase 1
Stem-like nerve cell treatment for severe nerve injuries
This Phase 1 study tests whether adding a patient’s own nerve support cells to a severely injured nerve is safe and helpful. It’s for people with recent major nerve damage in an arm or leg, with strict safety checks.
Miami, FloridaAges 18–65 - NCT05530655RecruitingEarly Phase 1
Finding the best lisinopril dose to prevent urine side effects
This early study tests which dose of lisinopril works best to help prevent urinary toxicity (urine/burning/urinary side effects) after radiation treatment for prostate cancer. If it’s effective for you, it could make radiation easier to tolerate.
Rochester, New YorkAges 18–70 - NCT05505513Recruiting
Test micro-electrode nerve implants for hand signal feedback
This study looks at whether tiny implanted sensors in a nerve can record brain/nerve signals and use them to provide feedback for people with a transradial arm amputation. If it works, it could help improve control or awareness with a prosthetic hand or related devices.
Salt Lake City, UtahAges 18–65
Common questions
- How many injuries & trauma clinical trials are recruiting?
- Clin2 is tracking 3,016 recruiting trauma studies from the U.S. registry right now, out of 4,936 we cover in this area in total.
- What does “Injuries & trauma” cover here?
- Wounds, fractures, and recovery from physical injury. We group each study into injuries & trauma based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a injuries & trauma trial near me?
- Use the search to filter injuries & trauma studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.