Trauma
Injuries & trauma clinical trials
Wounds, fractures, and recovery from physical injury. We’re tracking 3,219 recruiting studies in this area right now.
By phase
- Not applicable2,751
- Phase 2121
- Phase 4117
- Phase 187
- Phase 384
- Phase 1/Phase 237
- Phase 2/Phase 322
Top conditions
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Spinal Cord Injury100
- Trauma60
- Stroke56
- Anterior Cruciate Ligament Injuries44
- Amputation43
- Mild Traumatic Brain Injury41
- Hip Fractures40
- Rotator Cuff Tears40
- Radiotherapy Side Effect36
- Spinal Cord Injuries (SCI)35
- Carpal Tunnel Syndrome34
- Burns31
- Anterior Cruciate Ligament Rupture30
- Breast Cancer29
- Cardiotoxicity29
- Carpal Tunnel Syndrome (CTS)25
Leading sponsors
- VA Office of Research and Development37
- Cairo University36
- Riphah International University32
- Kessler Foundation21
- University of Miami21
- Johns Hopkins University20
- Sohag University19
- Mayo Clinic18
- Peking University Third Hospital18
- University of Texas Southwestern Medical Center18
Where studies are running
- California167
- Texas101
- New York85
- Florida80
- Illinois57
- Massachusetts57
- Pennsylvania52
- Ohio51
- Minnesota46
- Maryland42
Recruiting studies3,219 total
- NCT05410587Recruiting
Monitoring plate to improve healing after a femur fracture
This trial tests a special “monitoring” implant added to a surgical plate to track how a broken thigh bone (femur) is healing. It may help surgeons understand healing sooner so you can get the right weight-bearing and follow-up care.
HomburgAges 18 years+ - NCT05406635Recruiting
Imaging vs blood tests to guide heart-safe HER2 treatment
This trial compares whether special heart imaging or blood tests better helps monitor heart safety while you receive HER2-targeted therapy (like trastuzumab, with or without pertuzumab) plus chemotherapy. It may help doctors catch early heart stress and choose the safest treatment plan for you.
AalborgAges 18–90 - NCT05412381RecruitingPhase 3
PRP after ACL injury to help prevent knee arthritis
This study tests whether PRP (platelet-rich plasma) given after an ACL injury and surgery can lower the chance of developing long-term knee arthritis. It may help protect the knee over time by targeting early healing after ACL reconstruction.
New York, New YorkAges 14–50 - NCT05413707Recruiting
CT-measured ankle fracture study for specific break pattern
This study looks at adults with a specific type of ankle fracture involving the back part of the ankle bone (posterior malleolus) plus a certain side fracture. It uses CT scan measurements to guide how the fracture is classified and studied, and it requires you to be willing and able to follow study instructions.
Bergen, VestlandAges 18–65 - NCT05417737Recruiting
Ozone therapy for chronic pain when standard treatments fail
This study offers a palliative (comfort-focused) ozone treatment to adults with chronic pain when usual treatments don’t work or are too risky. Researchers will check whether adding ozone can help symptoms and whether it’s safe for selected patients.
Las Palmas, Las PalmasAges 18 years+ - NCT05423600Recruiting
Telehealth spinal stimulation plus exercise for high-level incomplete SCI
This study tests whether a home, therapist-guided exercise program combined with a spinal stimulation device (with or without limited blood flow) can improve movement and function in people with incomplete tetraplegia. It may help your muscles respond better, but participation depends on safety checks and your ability to do exercises by video.
Richmond, VirginiaAges 18–70 - NCT05423444Recruiting
Therapy for PTSD in teens using brain connectivity imaging
This study looks at how well PTSD-focused therapy changes brain “connectivity” patterns in adolescents. It may help your care team understand which teens benefit most from therapy.
San Antonio, TexasAges 12–17 - NCT05424354RecruitingPhase 4
Test powder dressing vs usual care for recent burn wounds
This study compares a transforming powder dressing to the standard dressing for partial-thickness burn wounds. It aims to see whether the powder dressing helps wounds heal better and safely when used soon after the burn.
Orange, CaliforniaAges 18–65 - NCT05423860Recruiting
HALO prostate study for men with early prostate cancer
This trial studies HALO, a new “human analytics” approach, in men with early-stage prostate cancer. It may help doctors better assess or guide care using MRI and biopsy findings, before or around initial treatment.
Indian Wells, CaliforniaAges 45–90 - NCT05424172Recruiting
Smartphone coaching to boost exercise after spinal cord injury
This study tests a smartphone program and coaching to help people with spinal cord injury follow recommended exercise routines. It may help you increase how much you exercise and improve adherence to exercise guidelines.
Chicago, IllinoisAges 18–80 - NCT05425810Recruiting
Smart tool to help check prosthetic socket fit
This study tests an easy-to-use smart system (called ENABLE) that helps assess whether a prosthetic socket fits your leg well. It may help improve comfort and reduce skin problems by making sure the socket fit is assessed in a consistent, affordable way.
Raleigh, North CarolinaAges 18–99 - NCT05426967Recruiting
Brain stimulation for depression after mild traumatic brain injury
This trial studies a noninvasive brain treatment (rTMS) to reduce depression symptoms in people with past mild traumatic brain injury from military service. It may help by changing brain activity, while also requiring stable mental health care and regular follow-up.
Palo Alto, CaliforniaAges 18–55 - NCT05427708Recruiting
Breathing training to reduce anxiety symptoms
This study tests whether specific respiratory (breathing) training can reduce anxiety symptoms and fear responses. It may help people who have several kinds of anxiety or trauma-related anxiety, especially if they are not on anxiety medicines or only stable on them.
Austin, TexasAges 18 years+ - NCT05431101Recruiting
Absorbable versus non-absorbable stitches after carpal tunnel surgery
This study compares two types of stitches used to close the skin after carpal tunnel release surgery. It may help show which stitch type leads to better healing and comfort afterward.
ApeldoornAges 18 years+ - NCT05437575RecruitingPhase 3
Testing pain medicine given before arrival to a trauma center
This study tests whether giving pain medicine soon after an injury (before you reach the trauma center) improves comfort and care. You might be eligible if you’re transported to a participating trauma center and meet specific shock and pain levels.
San Diego, CaliforniaAges 18 years+ - NCT05439850RecruitingPhase 4
Bioinductive patch for severe torn shoulder tendons
This trial studies a special patch placed during minimally invasive shoulder surgery to help heal full-thickness rotator cuff tears. It may help people whose tears are large or massive and who already tried non-surgical treatment without enough improvement.
Detroit, MichiganAges 18 years+ - NCT05444465Recruiting
Implant test for severe partial rotator cuff shoulder tears
This study tests whether a specific implant (the REGENETEN bioinductive implant) helps heal severe partial-thickness rotator cuff tears in the shoulder. You might benefit if you have a high-grade tear that didn’t improve after months of physical therapy.
Rome, GeorgiaAges 18 years+ - NCT05446584RecruitingPhase 2
Study memory changes in people with past mild head injury
This Phase 2 study looks at how memory problems (amnestic mild cognitive impairment) may relate to a history of a mild traumatic brain injury. It compares people with a past mild head injury to people without one to better understand what might be driving memory symptoms.
Dallas, TexasAges 55 years+ - NCT05445960Recruiting
Tourniquet use during ankle surgery and recovery outcomes
This study looks at whether using a tourniquet during ankle fracture surgery affects healing, leg movement, and patient-reported recovery. It may help doctors choose the safest, most comfortable approach for surgery.
Portland, OregonAges 18–89 - NCT05448807RecruitingPhase 3
Phentolamine to reverse numbing from dental local anesthesia in kids
This trial studies whether phentolamine can quickly undo (reverse) the numbness from local anesthesia used during dental procedures in children. It may help kids feel normally sooner and safely use their mouth (like speaking and drinking) after treatment.
Cairo, El ManialAges 5–7 - NCT05448703Recruiting
Predicting radiation lung injury after lung cancer treatment
This study looks at ways to predict who will develop radiation pneumonitis (lung inflammation after radiation) and how outcomes vary. It may help doctors better watch and treat lung side effects after lung cancer radiation.
Wuhan, HubeiAges 18 years+ - NCT05449834RecruitingPhase 3
Testing early fibrinogen treatment after serious trauma bleeding
This Phase 3 study tests whether giving fibrinogen early can improve outcomes for adults with serious trauma who are actively bleeding. The goal is to help blood clotting work better sooner and potentially reduce complications from uncontrolled bleeding.
Newcastle, New South WalesAges 18–100 - NCT05450510Recruiting
Testing slow vs faster rehab for severe shoulder tears
This study compares two physical therapy rehab plans to see which helps people recover better after a severe, irreparable rotator cuff tear. It may help you find the pace of rehab that works best for your shoulder and daily function.
KırşehirAges 18–65 - NCT05454267Recruiting
Study early blood vessel changes from vaping
This study looks for early signs of blood vessel problems in people who vape and in healthy non-vapers. It may help researchers find ways to detect and prevent vaping-related vascular disease early.
Miami, FloridaAges 18–40
Common questions
- How many injuries & trauma clinical trials are recruiting?
- Clin2 is tracking 3,219 recruiting trauma studies from the U.S. registry right now, out of 5,138 we cover in this area in total.
- What does “Injuries & trauma” cover here?
- Wounds, fractures, and recovery from physical injury. We group each study into injuries & trauma based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a injuries & trauma trial near me?
- Use the search to filter injuries & trauma studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.