Trauma
Injuries & trauma clinical trials
Wounds, fractures, and recovery from physical injury. We’re tracking 3,219 recruiting studies in this area right now.
By phase
- Not applicable2,751
- Phase 2121
- Phase 4117
- Phase 187
- Phase 384
- Phase 1/Phase 237
- Phase 2/Phase 322
Top conditions
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Spinal Cord Injury100
- Trauma60
- Stroke56
- Anterior Cruciate Ligament Injuries44
- Amputation43
- Mild Traumatic Brain Injury41
- Hip Fractures40
- Rotator Cuff Tears40
- Radiotherapy Side Effect36
- Spinal Cord Injuries (SCI)35
- Carpal Tunnel Syndrome34
- Burns31
- Anterior Cruciate Ligament Rupture30
- Breast Cancer29
- Cardiotoxicity29
- Carpal Tunnel Syndrome (CTS)25
Leading sponsors
- VA Office of Research and Development37
- Cairo University36
- Riphah International University32
- Kessler Foundation21
- University of Miami21
- Johns Hopkins University20
- Sohag University19
- Mayo Clinic18
- Peking University Third Hospital18
- University of Texas Southwestern Medical Center18
Where studies are running
- California167
- Texas101
- New York85
- Florida80
- Illinois57
- Massachusetts57
- Pennsylvania52
- Ohio51
- Minnesota46
- Maryland42
Recruiting studies3,219 total
- NCT05455034RecruitingPhase 1/Phase 2
Blood and lung-sample test to guide treatment for lung inflammation
This Phase 1/2 study uses detailed “single-cell” testing (from lung samples) to better understand why lung inflammation happens after cancer radiation or immunotherapy. It aims to help choose the right treatment approach for people with radiation pneumonitis or immune checkpoint inhibitor pneumonitis.
Chongqing, Chongqing MunicipalityAges 18–80 - NCT05458947Recruiting
Physical therapy wound treatments for spinal cord injury sores
This study tests different physical therapy approaches to help heal pressure sores on the sacrum or ischium in people with a spinal cord injury. You may be able to join if you’re already in inpatient rehabilitation and your wound severity score fits the study criteria.
Charlotte, North CarolinaAges 18 years+ - NCT05461326Recruiting
Compare two tendon grafts for ACL surgery recovery
This study compares two ways to rebuild the ACL using different tendon grafts (quadriceps tendon vs patellar tendon) taken from your own body. It aims to learn which option leads to better recovery after ACL reconstruction, including strength and function.
Birmingham, AlabamaAges 14–65 - NCT05464498Recruiting
Collagen device plus physiotherapy for Achilles tendon pain
This trial tests a collagen-based medical device used along with physical therapy to see if it helps people with Achilles tendon pain heal and improve function. You may be a good candidate if your symptoms are recent and the tendon problem is confirmed by ultrasound.
Roma, ROAges 18–70 - NCT05465031RecruitingPhase 4
Testing heart-protection medicine during breast cancer treatment
This trial tests sacubitril/valsartan to help prevent heart weakness (cardiotoxicity) caused by breast cancer treatments like anthracyclines and/or anti-HER2 drugs. If you qualify, you may be offered this heart-protection medicine while your cancer is treated.
Opole, Opole VoivodeshipAges 18 years+ - NCT05465070Recruiting
Heat therapy trial for leg blood-flow problems
This trial studies whether applying heat to your legs can improve symptoms and function in people with peripheral artery disease (reduced blood flow to the legs). You may be tested with a simple blood-flow check and an MRI scan, depending on eligibility.
Indianapolis, IndianaAges 50 years+ - NCT05467215RecruitingEarly Phase 1
Brief oxygen breathing trial after spinal cord injury
This early-phase study tests whether a short period of breathing extra oxygen (hyperoxia) soon after lying in one position can improve physical function in people with long-term spinal cord injury. If you qualify, the goal is to see whether this treatment can help your body work better after chronic injury.
Edmonton, AlbertaAges 18–65 - NCT05470790Recruiting
Arabic questionnaire study for ACL knee injury athletes
This study uses Arabic versions of questionnaires to measure knee control and sports cutting/pivoting ability after a one-sided ACL (knee ligament) injury. It may help researchers better evaluate recovery and readiness for sports in Arabic-speaking athletes.
Dammam, Eastern ProvinceAges 18–45 - NCT05472584Recruiting
Spinal stimulation with training for leg movement after injury
This study tests whether spinal cord stimulation combined with training can improve your ability to move your legs and do daily tasks. You may be able to join if you have a traumatic incomplete spinal cord injury (or, in some cases, if you’re a healthy volunteer).
St Louis, MissouriAges 16–65 - NCT05473689Recruiting
Sleep study in early spinal cord injury
This study looks at how sleep quality affects movement problems after a new spinal cord injury. Researchers hope to identify sleep targets that could improve motor function during recovery.
Toronto, OntarioAges 18 years+ - NCT05474066Recruiting
Testing brain function changes before and after deployment
This study looks at how the brain’s attention and information-processing skills change around major military changes. It may help researchers better understand who is affected and how to support performance and recovery.
Ottawa, OntarioAges 18–65 - NCT05484557Recruiting
Apixaban vs enoxaparin to prevent blood clots after spinal cord injury
This trial studies whether apixaban works as well as enoxaparin to prevent dangerous blood clots after spinal cord injury. If you qualify, you would take one of these medicines to lower clot risk during the recovery period.
RaananaAges 18 years+ - NCT05484739Recruiting
Testing cooling methods for heat waves in older adults
This study looks at how different cooling methods affect older adults during heat waves. It may help identify safer ways to reduce heat-related stress for people at risk.
Dallas, TexasAges 65 years+ - NCT05488080Recruiting
Improving emergency care for children with appendicitis or fractures
This project looks at how emergency department care is delivered for children with possible appendicitis or a long bone fracture, with a focus on reducing inequities. You may be eligible if your child comes to the emergency department for symptoms that could fit these conditions, and they are not in the most immediately life-threatening category.
Washington D.C., District of ColumbiaAges birth+ - NCT05488054Recruiting
Checking oxygen levels and blood counts during ACL rehab
This study measures oxygen levels in your muscles and hemoglobin (a blood protein that carries oxygen) while you recover after arthroscopic hip surgery. It may help researchers understand how the body responds during rehabilitation after orthopedic surgery.
Avon, OhioAges 14–30 - NCT05491525RecruitingPhase 2/Phase 3
Vibegron for children with nerve bladder using intermittent catheter
This study tests how well and how safely vibegron works long-term in children (ages 2 to under 18) with a nerve-related bladder condition, who regularly use intermittent catheterization. It also tracks how the body processes the medicine and whether it helps bladder control over time.
Little Rock, ArkansasAges 2–17 - NCT05492188Recruiting
Testing training and skin reflex changes for nerve pain after SCI
This study looks at how a training program affects skin reflexes and nerve pain in people with spinal cord injury (SCI). It may help researchers find better ways to manage nerve pain by changing how the body responds to touch and training.
Charleston, South CarolinaAges 18 years+ - NCT05493514Recruiting
Robotic training program for walking and balance
This trial studies whether a robotic training system (called G-EO) can help people with neurological conditions improve walking and balance. It may help by testing which factors predict who benefits most, and it requires regular training sessions.
MilanAges 18 years+ - NCT05498038Recruiting
Exercise program to help military concussion recovery
This trial studies whether a structured exercise “reset” program can improve recovery after concussion in active-duty service members. There are two groups: one soon after a new concussion and one with either lingering symptoms or a more recently recovered concussion.
Fayetteville, North CarolinaAges 18–40 - NCT05501210Recruiting
Knee vibration therapy for ongoing front-of-knee pain after ACL surgery
This trial studies whether a vibrating device on the front of the knee can reduce persistent pain after ACL reconstruction. It may help people whose pain is focused in one knee and isn’t caused by arthritis or other knee problems.
Hong KongAges 18–60 - NCT05507164RecruitingPhase 2
Study tests a jaw nerve block in healthy people
This trial studies how a “temporomasseteric nerve block” (a numbing shot near jaw muscles) works in healthy volunteers. It’s mainly looking at safety and how people respond—so it’s not for treating an existing jaw pain condition.
Newark, New JerseyAges 18–64 - NCT05514405Recruiting
Testing two anesthesia medicines to prevent confusion after surgery
This trial tests whether using remimazolam or propofol during hip or knee replacement surgery can lower the risk of postoperative delirium, a sudden, short-term confusion that can happen after anesthesia. It may help people who are at higher risk of postoperative confusion by finding the safer anesthesia approach.
SeoulAges 65–100 - NCT05527509Recruiting
Study of risk and resilience in new RCMP cadets
This study follows people as they start RCMP Cadet Training to learn what factors affect “risk” and “resilience” (how well someone adapts under stress). It may help improve support for cadets during training.
Regina, SaskatchewanAges 19–57 - NCT05530655RecruitingEarly Phase 1
Finding the best lisinopril dose to prevent urine side effects
This early study tests which dose of lisinopril works best to help prevent urinary toxicity (urine/burning/urinary side effects) after radiation treatment for prostate cancer. If it’s effective for you, it could make radiation easier to tolerate.
Rochester, New YorkAges 18–70
Common questions
- How many injuries & trauma clinical trials are recruiting?
- Clin2 is tracking 3,219 recruiting trauma studies from the U.S. registry right now, out of 5,138 we cover in this area in total.
- What does “Injuries & trauma” cover here?
- Wounds, fractures, and recovery from physical injury. We group each study into injuries & trauma based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a injuries & trauma trial near me?
- Use the search to filter injuries & trauma studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.