Trauma
Injuries & trauma clinical trials
Wounds, fractures, and recovery from physical injury. We’re tracking 3,218 recruiting studies in this area right now.
By phase
- Not applicable2,751
- Phase 2121
- Phase 4117
- Phase 186
- Phase 384
- Phase 1/Phase 237
- Phase 2/Phase 322
Top conditions
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Spinal Cord Injury100
- Trauma60
- Stroke56
- Anterior Cruciate Ligament Injuries44
- Amputation43
- Mild Traumatic Brain Injury41
- Hip Fractures40
- Rotator Cuff Tears40
- Radiotherapy Side Effect36
- Spinal Cord Injuries (SCI)35
- Carpal Tunnel Syndrome34
- Burns31
- Anterior Cruciate Ligament Rupture30
- Breast Cancer29
- Cardiotoxicity29
- Carpal Tunnel Syndrome (CTS)25
Leading sponsors
- VA Office of Research and Development37
- Cairo University36
- Riphah International University32
- Kessler Foundation21
- University of Miami21
- Johns Hopkins University20
- Sohag University19
- Mayo Clinic18
- Peking University Third Hospital18
- University of Texas Southwestern Medical Center18
Where studies are running
- California168
- Texas101
- New York85
- Florida80
- Illinois57
- Massachusetts57
- Pennsylvania52
- Ohio51
- Minnesota46
- Maryland42
Recruiting studies3,218 total
- NCT05855252Recruiting
Study on monitoring and outcomes after moderate to severe head injury
This observational study follows adults with moderate to severe traumatic brain injury to understand care and outcomes. It collects information from the first 48 hours in the ICU and may help improve how clinicians monitor and treat patients in the critical early period.
Kogarah, New South WalesAges 18 years+ - NCT05855759Recruiting
New graft to help repair large rotator cuff tears
This trial studies a special “acellular” (cell-free) skin-derived graft combined with healing-stimulating materials to improve healing and function after surgery for large rotator cuff tears. It may help people with serious tendon damage in the shoulder, but only if their tear type and health situation fit the study rules.
Bologna, BOAges 18–65 - NCT05856539Recruiting
Numbing nerve block during minimally invasive low back surgery
This trial tests whether an “ESP block” (a numbing injection near the spine) can help control pain during minimally invasive low back fusion surgery. If you’re having this surgery, the goal is to improve comfort and reduce pain medicine needs.
New York, New YorkAges 18–80 - NCT05857774Recruiting
Study breathing muscle changes in ICU patients on ventilation
This study looks at how the muscles used for breathing work and change in ICU patients who are placed on breathing machines, then follows outcomes after they leave the hospital. It may help doctors better predict recovery and long-term health after ventilation.
Toronto, OntarioAges 18 years+ - NCT05858060Recruiting
Osmotic treatment for severe bleeding around the brain
This trial looks at an “osmotic therapy” (a treatment meant to pull fluid away from swelling areas) for adults with severe bleeding around the brain caused by a burst aneurysm. It may help reduce dangerous swelling or complications, but your eligibility depends on your stability and lab results.
Beijing, Beijing MunicipalityAges 18–85 - NCT05859451Recruiting
Heated tobacco product study for surgically treated leg fractures
This study looks at whether a tobacco heating system (instead of cigarettes) affects how well a surgically repaired tibia or femur fracture heals. It mainly targets smokers with a certain smoking history who do not want to join free smoking-cessation seminars.
Tübingen, Baden-WurttembergAges 18 years+ - NCT05863754Recruiting
Networked device that helps assess hand muscle movement
This trial tests a networked neuroprosthesis device designed to interact with nerves in the arm/hand to help assess grasp and release movements. It may help people with certain long-term spinal cord injuries regain more controlled hand function and researchers measure how well the system works.
Cleveland, OhioAges 16 years+ - NCT05865327Recruiting
Nerve freezing for rib-fracture pain using ultrasound guidance
This trial tests whether freezing a specific nerve (a “cryoneurolysis” treatment) through a catheter can better control pain from traumatic rib fractures. It’s offered to adults who have rib fractures soon after hospital admission and can use a pain control method called patient-controlled regional analgesia.
Toronto, OntarioAges 18–100 - NCT05866029Recruiting
Prevention and treatment study for new brittle bone fractures
This study looks at ways to prevent and treat “brittle bone” refractures after a recent fracture in people with osteoporosis. If you’ve had a new hip, spine, or other bone fracture, the trial may test strategies to lower the chance of another fracture.
BeijingAges 45–90 - NCT05869851Recruiting
Infant hip ultrasound study: observe vs bracing
This study looks at babies under 3 months old with certain ultrasound findings of an underdeveloped hip (“hip dysplasia”). It compares outcomes between simply watching the hip and using a brace (when recommended).
Vancouver, British ColumbiaAges Up to 3 months - NCT05876208Recruiting
Home physical therapy help to improve shoulder rehab
This study tests a home-based physical therapy program using a phone or web platform (VirtuaCare) to help people stick with their post-surgery shoulder exercises. It may help improve how consistently you complete standard rehab after certain shoulder operations.
Cincinnati, OhioAges 18 years+ - NCT05883241RecruitingPhase 1
Sound-based treatment for fracture pain
This early-stage study tests a device that uses sound to reduce pain from a bone fracture and improve daily quality of life. If you have mild-to-moderate fracture pain and can follow the device routine, you may be able to try this treatment while avoiding other pain medicines and fracture-area therapies.
Trumbull, ConnecticutAges 18–80 - NCT05885529Recruiting
Blood and CT tests after a concussion to track brain injury
This study checks whether two blood proteins (GFAP and UCH-L1) can help identify which brain spots are linked to a significant head injury after a concussion. You may be able to help by providing a blood sample and getting a CT scan as part of usual care, so doctors can better sort out injury risk.
AngersAges 18 years+ - NCT05889650Recruiting
External drainage for severe TBI brain swelling
This study tests whether placing an external drainage tube in the lower back can reduce dangerous pressure in the brain after a severe traumatic brain injury. If you meet safety and brain-scan criteria, it may help the research team understand whether this approach is safe early after injury.
Gainesville, FloridaAges 18–65 - NCT05889559Recruiting
Testing a fluid drainage method to detect leg pressure problems
This study looks at a special drainage measurement (“tissue ultrafiltration”) to better detect and treat acute compartment syndrome, a dangerous increase in pressure in the leg after major injury. It may help doctors identify who needs urgent treatment and improve outcomes after severe leg fractures or crush injuries.
Baltimore, MarylandAges 18–60 - NCT05891704Recruiting
Rehab program for traumatic hand injuries in Palestinian Arabs
This study tests a hand-rehabilitation program designed to fit cultural and language needs. It may help people recover hand function after an injury below the elbow, but only for a specific group and injury type.
JeninAges 16–65 - NCT05894265Recruiting
Test collagen patch versus standard care after rotator cuff repair
This study compares a collagen “patch” placed during arthroscopic rotator cuff surgery versus the usual standard repair. It looks at safety and whether the patch improves healing and shoulder function after surgery.
Houston, TexasAges 18–80 - NCT05895604Recruiting
Support study for first-time mothers during early pregnancy
This study is for women who are pregnant for the first time and are earlier than 28 weeks. It aims to understand and improve support for pregnant people when professionals feel they may need extra help as parenthood approaches.
Bergen, BergenAges 16 years+ - NCT05896475Recruiting
Looking for who may develop shoulder pain from silent tears
This study looks at risk factors that predict when an “asymptomatic” (painless) rotator cuff tear might start causing symptoms. You may benefit by getting careful assessment and monitoring of your shoulder health over time.
Ghent, Oost-VlaanderenAges 55–100 - NCT05900778Recruiting
HABIT-ILE program for school-aged children after brain injury
This trial tests whether a structured HABIT-ILE program helps children with a brain injury improve daily functioning at school and during therapy sessions. It may help families build skills and routines, but it requires meeting specific health and timing criteria.
Ottignies-Louvain-la-Neuve, Brabant-WallonAges 5–18 - NCT05903859RecruitingPhase 3
Study to improve fertility in men after spinal cord injury
This phase 3 study tests a treatment to improve reproductive function (fertility-related measures) in men who have had a traumatic spinal cord injury. If you may be eligible, it could help researchers see whether the treatment improves reproductive outcomes for men with spinal cord injury.
Miami, FloridaAges 18 years+ - NCT05904353Recruiting
Care coordination program after hip fracture and osteoporosis
This trial aims to improve how primary care and hospital care work together to treat osteoporosis after a hip fracture. It may help by making follow-up treatment plans and communication clearer after your hip injury.
Lørenskog, AkershusAges 75 years+ - NCT05906004Recruiting
Follow-up study after Pitch-Patch shoulder repair
This study checks how well a Pitch-Patch device is doing to support the rotator cuff (a shoulder tendon). It enrolls people who had the device placed about 2 to 2.5 years ago so the researchers can follow outcomes and safety over time.
ReadingAges 16 years+ - NCT05906056Recruiting
CPM therapy vs bone overgrowth in hip or knee
This study compares continuous passive motion (a machine that gently moves a joint without you moving it) versus the body’s tendency to form extra bone called heterotopic ossification. It aims to see whether CPM can affect how and how much bone overgrowth develops after neurologic injuries like stroke, brain injury, or spinal cord injury.
Ioannina, EpirusAges 15–70
Common questions
- How many injuries & trauma clinical trials are recruiting?
- Clin2 is tracking 3,218 recruiting trauma studies from the U.S. registry right now, out of 5,144 we cover in this area in total.
- What does “Injuries & trauma” cover here?
- Wounds, fractures, and recovery from physical injury. We group each study into injuries & trauma based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a injuries & trauma trial near me?
- Use the search to filter injuries & trauma studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.