Nephrology & urology
Kidney & urinary clinical trials
Kidney disease and conditions of the bladder and urinary tract. We’re tracking 4,391 recruiting studies in this area right now.
By phase
- Not applicable2,721
- Phase 2568
- Phase 1363
- Phase 3265
- Phase 1/Phase 2227
- Phase 4192
- Phase 2/Phase 355
Top conditions
- Prostate Cancer645
- Bladder Cancer186
- Acute Kidney Injury134
- Chronic Kidney Diseases122
- Chronic Kidney Disease107
- Breast Cancer104
- Renal Cell Carcinoma80
- Urinary Incontinence60
- Kidney Cancer59
- Colorectal Cancer58
- Ovarian Cancer56
- Lung Cancer51
- Cancer48
- Lupus Nephritis48
- Melanoma47
- Head and Neck Cancer46
- Metastatic Prostate Cancer46
- Hypertension45
Leading sponsors
- Mayo Clinic64
- National Cancer Institute (NCI)48
- Peking University First Hospital39
- M.D. Anderson Cancer Center36
- Chinese University of Hong Kong35
- Novartis Pharmaceuticals33
- AstraZeneca29
- IRCCS Azienda Ospedaliero-Universitaria di Bologna29
- Memorial Sloan Kettering Cancer Center29
- Assistance Publique - Hôpitaux de Paris27
Where studies are running
- California358
- Arizona109
- Alabama107
- New York96
- Florida93
- Maryland91
- Texas91
- Massachusetts88
- Illinois66
- Minnesota50
Recruiting studies4,391 total
- NCT06263153RecruitingPhase 2
Futibatinib and durvalumab before bladder cancer surgery
This trial tests two drugs (futibatinib and durvalumab) given before bladder removal surgery for people with muscle-invasive bladder cancer who cannot take standard cisplatin chemotherapy. The goal is to see if the combination shrinks the tumor and improves outcomes.
Ann Arbor, MichiganAges 18 years+ - NCT06262139RecruitingPhase 1/Phase 2
New MRI dye for high-risk prostate cancer
This trial tests a new MRI contrast dye that might help doctors see aggressive prostate cancer more clearly. It is for men with high-risk prostate cancer (Gleason 8-10) who have already had an MRI and a biopsy.
Atlanta, GeorgiaAges 18–90 - NCT06267729RecruitingPhase 1/Phase 2
A new cell therapy for advanced prostate cancer
This trial tests a new cell therapy (AZD0754) for metastatic prostate cancer that has stopped responding to standard hormone therapy and chemotherapy. It’s looking for people whose cancer has gotten worse despite prior treatments, and who are still in fairly good health.
Duarte, CaliforniaAges 18–130 - NCT06270706RecruitingPhase 1
Study of a new drug for advanced solid tumors after immunotherapy
This study tests a new drug called PLN-101095 in people with advanced solid tumors whose cancer has stopped responding to a common immunotherapy. The goal is to see if combining this new drug with pembrolizumab can help control the cancer again.
New Haven, ConnecticutAges 18 years+ - NCT03329313RecruitingPhase 2
Adjusting dialysis salt levels for ICU kidney injury
This study tests whether using a specific salt (sodium) level in the dialysis fluid affects outcomes for adults in the ICU with sudden kidney failure. It may help your care team optimize dialysis settings during acute kidney injury.
Montpellier, MontpellierAges 18–80 - NCT06128278RecruitingPhase 2
Equol supplement and blood vessel health in women
This study tests whether taking an Equol supplement (a soy-related compound) improves blood vessel function in postmenopausal women with and without chronic kidney disease (CKD). It could help women with or without early-stage CKD learn if this supplement supports heart health.
Aurora, ColoradoAges 50–69 - NCT05867979Recruiting
Find hidden DNA changes in some boys with unclear DSD
This trial looks for “structural variants,” meaning larger DNA rearrangements that standard gene tests may miss, in boys with certain differences in sex development (DSD) when results are unclear. It may help provide a clearer diagnosis that can guide care for your family.
MontpellierAges 6 months+ - NCT06235697RecruitingPhase 3
Hormone therapy with or without lymph node radiation for prostate cancer
This trial tests combining hormone therapy with different types of radiation (including high-dose external beam and brachytherapy) for men with prostate cancer that has a higher chance of coming back. It aims to see if adding radiation to the lymph nodes helps control the cancer better.
Antioch, CaliforniaAges 18 years+ - NCT06243731Recruiting
Maribavir for CMV after transplant in kidney failure
This study looks at how well the drug maribavir works in adults with kidney failure who get a CMV infection after a transplant. It focuses on people whose CMV infection hasn't responded to other treatments.
Anderlecht, Brussels CapitalAges 18 years+ - NCT06242470RecruitingPhase 1
Study of MGC026 for advanced solid tumors
This trial tests a new drug called MGC026 that targets a protein called B7-H3 on cancer cells, aiming to shrink or slow different advanced solid tumors. It is an early-phase study to find the right dose and check safety.
Los Angeles, CaliforniaAges 18 years+ - NCT06234605RecruitingPhase 1
Study of a new combination for advanced kidney cancer
This trial tests an experimental drug (HC-7366) combined with an approved targeted therapy (belzutifan) for people with advanced kidney cancer. It aims to see if the combination is safe and works better than either drug alone.
Tucson, ArizonaAges 18 years+ - NCT04745195Recruiting
Study of complement activity in microangiopathy affecting kidneys
This study looks at signs of a clotting problem in tiny blood vessels (called TMA) that can affect kidney function. The goal is to better understand the role of the body’s complement system and how it relates to different causes of this illness.
Maastricht, LimburgAges 18 years+ - NCT06235892RecruitingPhase 3
Lowering Tacrolimus for Low-Risk Kidney Transplant Patients
This trial tests whether safely lowering the dose of tacrolimus—an anti-rejection drug—can still protect a kidney transplant one year after surgery. It's for first-time transplant recipients with low immune risk.
NantesAges 18 years+ - NCT06251713Recruiting
Fluid removal guided by VeXUS score after heart surgery
This trial tests if using a special ultrasound score (VeXUS) to guide fluid removal can improve recovery in patients with acute kidney injury after heart surgery. It compares this approach to standard care to see if it leads to better outcomes.
Bron, BronAges 18–85 - NCT06245603Recruiting
Testing Hydeal Cyst with standard treatment for bladder cancer
This study tests a bladder instillation called Hydeal Cyst, given alongside standard BCG or MMC therapy, to see if it helps reduce side effects or improve outcomes for people with non-muscle invasive bladder cancer.
BergamoAges 18 years+ - NCT06239272RecruitingPhase 1/Phase 2
Personalized treatment for NRSTS in children and young adults
This trial tests a personalized treatment plan for children and young adults with a type of soft tissue sarcoma (NRSTS). It uses a combination of surgery, targeted radiation, and two drugs (pazopanib and selinexor) to fight cancer while reducing side effects. The study is looking for people who have not been treated before for this sarcoma.
Atlanta, GeorgiaAges Up to 30 years - NCT06238661Enrolling by invitation
Prostate cancer screening pilot study for men 55-65
This study tests a new way to screen for prostate cancer in men aged 55 to 65 who live in a specific area of Italy. It aims to find cancer early when it's easier to treat.
Candiolo, ItalyAges 55–65 - NCT06234410Recruiting
Heart risk check before kidney transplant
This study uses a special heart CT scan (called coronary angiography) to check the heart health of people waiting for a kidney transplant. It aims to see if this scan can help doctors better assess and manage heart risks before surgery.
Edinburgh, LothianAges 16 years+ - NCT06243068Enrolling by invitation
Supporting decisions about kidney care without dialysis
This study helps people with advanced chronic kidney disease explore their care options, including the choice to manage without dialysis. It provides support and information to help you and your family make a decision that fits your values.
San Francisco, CaliforniaAges 65 years+ - NCT06229990RecruitingPhase 4
Using furosemide stress test to stop kidney replacement therapy
This study tests whether a furosemide (a water pill) stress test can help doctors decide when to safely stop continuous kidney replacement therapy in ICU patients with severe acute kidney injury. It may allow you to come off the machine sooner if your kidneys respond well.
Chiang MaiAges 20 years+ - NCT06242327Recruiting
Study of outcomes in primary membranous nephropathy
This trial looks at how people with primary membranous nephropathy (a kidney disease that causes swelling and protein in urine) do over time with their current treatment. It helps doctors understand which treatments work best, especially for those with severe protein loss.
Bergamo, BGAges 18 years+ - NCT06238713Recruiting
New vs. standard robotic prostate surgery for early cancer
This study compares two ways of doing robot‑assisted prostate removal surgery. It aims to see if a newer, less invasive method through a single small cut is as safe and effective as the standard method. If you have early‑stage prostate cancer and are eligible, you could help improve surgical recovery.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06244004RecruitingPhase 2
PET-guided radiation for metastatic hormone-sensitive prostate cancer
This trial tests whether using a special PET scan (FDG-PET) to find and treat only the spots where cancer has spread with targeted radiation can help men with prostate cancer that has spread but still responds to hormone therapy. It compares standard treatment alone to standard treatment plus this targeted radiation.
Chicago, IllinoisAges 18 years+ - NCT06237179RecruitingPhase 1/Phase 2
Exercise program to reduce heart risk in prostate cancer
This study tests whether a supervised exercise program can help reduce heart disease risk in men with prostate cancer who are on hormone therapy. Participants will exercise at home or in a group and be monitored for heart health changes.
Richmond, VirginiaAges 40–85
Common questions
- How many kidney & urinary clinical trials are recruiting?
- Clin2 is tracking 4,391 recruiting nephrology & urology studies from the U.S. registry right now, out of 6,874 we cover in this area in total.
- What does “Kidney & urinary” cover here?
- Kidney disease and conditions of the bladder and urinary tract. We group each study into kidney & urinary based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a kidney & urinary trial near me?
- Use the search to filter kidney & urinary studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.