Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06651658Recruiting
A trial of pleura embolisation during lung ablation
This study looks at a new procedure called pleural embolisation that may reduce air leaks after lung ablation. It tests whether using this technique during ablation is safe and effective for people with lung lesions.
OxfordAges 18 years+ - NCT06652048RecruitingPhase 2
High-dose Furmonertinib for advanced lung cancer after progression
This trial tests a higher dose of the targeted therapy Furmonertinib, either alone or with chemotherapy, for people with advanced non-small cell lung cancer that has progressed after initial treatment with a third-generation EGFR inhibitor like Osimertinib or Almonertinib.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06652204Recruiting
Questionnaire for caregivers of COPD patients
This study tests a French questionnaire for caregivers of people with COPD. It aims to better understand caregiver burden and support needs.
BrestAges 18 years+ - NCT06653478Recruiting
Smarter cancer risk assessment using all your medical info
This study is testing a new way to use medical images, records, and other information to better assess cancer risk and guide treatment. It may be a good fit if you have a suspicious spot in your lungs, stomach, or colon, or if you are healthy and want to help with early cancer detection research.
Wuhan, HubeiAges 18–75 - NCT06653569RecruitingPhase 3
Baloxavir for flu in hospitalized adults
This trial tests if the antiviral drug baloxavir can help adults hospitalized with influenza recover faster. It compares baloxavir to a placebo to see if it improves symptoms and outcomes.
Geneva, Canton of GenevaAges 18 years+ - NCT06653556RecruitingEarly Phase 1
LCAR-AIO for relapsed or hard-to-treat lupus
This study tests a new treatment called LCAR-AIO for people with systemic lupus erythematosus (SLE) that has come back or not responded well to standard therapies. The goal is to see if it can help control the disease.
Wuhan, HubeiAges 18–65 - NCT06654752Recruiting
Simpler treatment for lung flare-ups in kids with CF
This study tests a streamlined approach to managing sudden lung symptoms (pulmonary exacerbations) in children with cystic fibrosis. It aims to see if a simpler treatment plan works as well as standard care, which could mean less time in the hospital and fewer disruptions to daily life.
Birmingham, AlabamaAges 3–18 - NCT06655090Recruiting
Early detection and treatment study for lung scarring disease
This study looks at how to find and treat fibrotic interstitial lung disease (a condition where lung tissue becomes scarred and stiff) as early as possible. It may help people with this type of lung disease get better care.
Beijing, Beijing MunicipalityAges Any age - NCT06655272RecruitingPhase 4
OM 85 to prevent lung infections in older nursing home residents
This study tests a medication called OM 85 that may help prevent respiratory infections (like pneumonia) in older adults living in nursing homes. If you are 75 or older and have had infections recently, this trial could be a way to stay healthier.
Roma, RMAges 75 years+ - NCT06655337Recruiting
Testing a smartphone app for managing hospital discharge
This study tests whether a smartphone app called Medidux helps you manage your symptoms and discharge from the hospital if you came in with coughing, back pain, or belly discomfort. You'll use the app to report how you're feeling, and the care team can check in with you after you leave.
Horgen, Canton of ZurichAges 18 years+ - NCT06655428Recruiting
A new treatment for severe emphysema using heat and liquid
This trial tests a procedure called Endobronchial Thermal Liquid Ablation (ETLA) that uses heated liquid to treat severe emphysema. It is for people with COPD who have very low lung function and shortness of breath, and who have not been able to get relief from other treatments.
Vienna, AustriaAges 40 years+ - NCT06656299Recruiting
Nerve block for gallbladder removal surgery
This study tests a nerve block called EOIB to see if it helps reduce pain after gallbladder removal surgery. If you are having planned gallbladder surgery, this might be a good option for you.
IstanbulAges 18–65 - NCT06657898Recruiting
Complicated pneumonia in children in Southeast Europe
This study looks back at children who had a serious type of pneumonia (complicated pneumonia) between 2014 and 2024 in Southeast Europe. It aims to learn more about these infections to help improve care for kids in the future.
BelgradeAges 1 month–18 years - NCT06658080Recruiting
Testing drugs on fluid from breast cancer
This trial uses fluid from the chest or belly of breast cancer patients to grow tiny tumor models in the lab. These models help doctors find which drugs might work best for each patient.
Hangzhou, ZhejiangAges 18–70 - NCT06658535RecruitingPhase 1
Study of NanO2 for mild breathing problems
This trial tests an experimental drug called NanO2 for people with mild respiratory distress who need a small amount of extra oxygen. The goal is to see if it can help improve oxygen levels.
Edmonton, AlbertaAges 18 years+ - NCT06658522RecruitingPhase 4
Sotatercept for right heart function in pulmonary hypertension
This study tests a medicine called sotatercept to see if it can improve how the right side of your heart pumps in people with PAH. It may help you feel better and slow down the disease.
Amsterdam, North HollandAges 18–70 - NCT06659042RecruitingPhase 2
Tislelizumab before and after surgery for KRAS-mutated lung cancer
This trial tests whether adding the immunotherapy drug tislelizumab before and after surgery can help people with a specific type of lung cancer (non-squamous NSCLC with a KRAS mutation) that is stage 2 or 3. It aims to improve treatment outcomes by targeting the cancer early.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06659458Recruiting
EGFR lung cancer gene study using advanced DNA sequencing
This trial uses long-read sequencing to study the EGFR gene in women with EGFR-positive lung cancer. It aims to learn more about the cancer's DNA to improve future treatments.
Baton Rouge, LouisianaAges 18–100 - NCT06659887Recruiting
Testing breathing rates in children during surgery
This study looks at how different slow breathing rates (low flow rates) affect oxygen and carbon dioxide levels in children who are under general anesthesia and not breathing on their own. It may help doctors choose the best settings for safe surgery.
Al Fayyum, Faiyum GovernorateAges 1–6 - NCT06660407RecruitingPhase 2
Grid radiation for advanced lung cancer after immunotherapy
This trial tests a special type of radiation called grid therapy for people with stage IV non-small cell lung cancer that has grown after immunotherapy or chemoimmunotherapy. It aims to see if this approach can help control tumors that are larger than 3 centimeters outside the brain.
Rochester, MinnesotaAges 18 years+ - NCT06660537Recruiting
Balloon breathing exercises for asthma patients
This trial tests whether doing balloon-blowing exercises in a specific lying position can improve lung function in people with mild asthma. It may help you breathe easier.
Rawalpindi, Punjab ProvinceAges 18–59 - NCT06662630Recruiting
Oscillatory ventilation study for ICU patients on breathing machines
This study tests a new breathing method (high-frequency oscillatory ventilation) for patients in the ICU who need a breathing tube. It looks at how safe it is and how it affects the body, and is for people with certain lung problems like ARDS or collapsed lungs.
Shanghai, Shanghai MunicipalityAges 20–90 - NCT06663098RecruitingPhase 2
Atezolizumab and chemo again for relapsed small cell lung cancer
This trial tests a combination of a second course of chemotherapy and an immunotherapy drug (atezolizumab) for people with extensive-stage small cell lung cancer that has returned after initial treatment. The goal is to see if re-using these treatments together can help control the cancer again.
Aviano (PN)Ages 18 years+ - NCT06663306RecruitingPhase 1
Intrathecal pemetrexed and bevacizumab for lung cancer brain spread
This trial tests a treatment given directly into the fluid around the brain and spinal cord (intrathecal injection) using two drugs—pemetrexed and bevacizumab—for people with non-small cell lung cancer that has spread to that area (leptomeningeal metastases). It may be an option if your current treatment is no longer working.
ShanghaiAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.