Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT06727578Recruiting
Pleural irrigation with a new device
This trial tests a new device to wash out fluid that stays in the chest after a chest tube is placed. It might help people who cannot receive standard medication to break up this fluid within the first day after their chest tube is inserted.
Boston, MassachusettsAges 18 years+ - NCT06731413RecruitingPhase 2
Mild chemo with immunotherapy for older adults with advanced lung cancer
This study tests a milder chemotherapy combined with an immunotherapy drug (anti-PD-1) as the first treatment for advanced lung cancer in older or frailer adults. It aims to see if this approach works better with fewer side effects.
Richmond, VirginiaAges 18 years+ - NCT06727864RecruitingPhase 3
Short-course treatment for low-risk active lung TB
This trial tests a shorter treatment course (instead of the standard 6 months) for people with low-risk active TB in the lungs. It aims to see if the shorter regimen works just as well and has fewer side effects.
New Taipei City, BangiaoAges 20–99 - NCT06731270RecruitingPhase 2
Diclofenac for advanced lung cancer on immunotherapy
This trial tests whether adding the anti-inflammatory drug diclofenac can help people with advanced non-small cell lung cancer whose tumors are growing while on a single immunotherapy drug. You must have been on immunotherapy for at least 12 weeks and have a growing tumor, but your doctor does not plan to change your treatment right away.
Atlanta, GeorgiaAges 18 years+ - NCT06738160RecruitingPhase 2
Combination therapy for advanced lung cancer with bone metastases
This trial tests a new combination of drugs and radiation to improve the effects of first-line chemotherapy and immunotherapy for patients with advanced non-small cell lung cancer that has spread to the bones. The goal is to help shrink tumors and potentially improve overall outcomes.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06732193Recruiting
Fissios App for recovery after lung cancer surgery
This trial tests whether using a smartphone app (Fissios) after lung cancer surgery helps you recover with fewer complications. If you are scheduled for lung surgery for non-small cell lung cancer and have a smartphone, you may be eligible.
Madrid, MadridAges 18 years+ - NCT06728904Enrolling by invitation
High-intensity Tai Chi for mild to moderate asthma
This trial tests if a high-intensity Tai Chi program can help people with mild to moderate asthma. It aims to improve lung function and control asthma symptoms.
ShanghaiAges 18 years+ - NCT06731244Recruiting
Deciding about blood thinners after a first clot
This study helps you and your doctor decide together whether to continue blood thinners after a first unexpected blood clot. You join after 3 to 6 months of treatment to discuss your options.
Brest, FranceAges 18 years+ - NCT06735976Recruiting
Safety and effectiveness of LOBO device for PAVM treatment
This study tests a new device (LOBO™) to block abnormal blood vessels in the lungs called PAVMs. It is for people with HHT or similar conditions, and the device is placed into the vessel to reduce the risk of stroke or bleeding. You may be able to join if you have a suitable PAVM that is large enough and you are not taking blood thinners.
Chapel Hill, North CarolinaAges 14 years+ - NCT06730685Enrolling by invitation
Sarcopenia and cachexia in lung cancer patients
This study looks at muscle loss (sarcopenia) and weight loss (cachexia) in people with lung cancer. Researchers want to understand these conditions better to improve care.
Næstved, Region SjællandAges 18 years+ - NCT06731881Recruiting
Light therapy to prevent infections after sinus or nose surgery
This study tests if a special light therapy can help prevent infections after sinus or nose surgeries. The treatment is given in addition to standard care and might lower the chance of needing more antibiotics.
London, LondonAges 16 years+ - NCT05442060RecruitingPhase 2
Test medicine add-on to erlotinib for EGFR lung cancer
This Phase 2 trial tests whether adding OBI-833/OBI-821 to the standard targeted pill erlotinib works better for some people with EGFR-mutated lung cancer. It may help shrink tumors that already started responding to erlotinib.
Taipei, Beitou DistrictAges 20 years+ - NCT06726720Recruiting
Real-world study of approved lung cancer drugs
This study looks at how well approved AstraZeneca drugs work for non-small cell lung cancer in everyday medical practice. It does not test new treatments, but gathers information to help doctors and patients make better decisions.
Aix-en-ProvenceAges 18 years+ - NCT06726148RecruitingPhase 1/Phase 2
Study of ECI830 for advanced breast cancer and solid tumors
This trial is testing a new drug called ECI830, either alone or with another drug, for people with advanced breast cancer or other solid tumors that have not responded to standard treatments. It may be an option if you have HR+/HER2- breast cancer, small cell lung cancer, or a tumor with a specific gene change (CCNE1 amplification).
Los Angeles, CaliforniaAges 18–100 - NCT06717295Recruiting
Blood test to find cancer early and track treatment
This study uses a blood test that looks at your platelets and immune cells to find common cancers early, and for certain cancers, to monitor how well treatment is working.
RosarioAges 40–75 - NCT06716606RecruitingPhase 3
Long-term safety of belimumab for lung disease in scleroderma and other connective tissue diseases
This study tests the long-term safety and effectiveness of belimumab for people with lung scarring caused by scleroderma or other connective tissue diseases. It is for patients who already completed a one-year study with belimumab and were not considered treatment failures.
Los Angeles, CaliforniaAges 18 years+ - NCT06724848Recruiting
Studying Biomarkers and COPD Types in Chinese People
This study looks at signs (biomarkers) and different types of COPD in Chinese people. It aims to better understand COPD and pre-COPD, which may help with future treatments.
BeijingAges 30 years+ - NCT06722755Recruiting
CPAP for Sleep Apnea After Stroke
This study tests whether using a CPAP machine (a device that helps you breathe while sleeping) can improve recovery after a recent stroke or brain bleed. You may join if you had a stroke in the past month and are not already using CPAP.
Downey, CaliforniaAges 18 years+ - NCT06717659Recruiting
Probiotics for lung rehab in COPD patients
This trial tests if adding probiotics (healthy bacteria you take as a supplement) to your regular lung rehab program helps people with COPD breathe better and feel stronger.
New Taipei CityAges 18 years+ - NCT06719258Recruiting
Trial on heated humidifiers for breathing tubes
This trial studies how heating and adding moisture to the air breathed through a breathing tube (called a heated humidifier) affects patients in intensive care. It focuses on people who need the breathing tube for a longer time or special protective settings.
Québec, QuebecAges 18 years+ - NCT06722365Recruiting
Fetal lung study using ultrasound
This study uses a special ultrasound to look at your baby's lung development in the last weeks of pregnancy. It may help doctors learn more about how healthy lungs grow before birth.
Madison, WisconsinAges 18–45 - NCT06726590Recruiting
Gene testing for better medication outcomes
This study collects blood, urine, and cheek swabs, along with health information, to see how your genes affect your response to medications. You may be eligible if you take many medications or are on blood pressure or depression medication.
Bryan, TexasAges 18 years+ - NCT06719700RecruitingPhase 2
Chemo-radiation with two drugs for limited-stage small cell lung cancer
This trial tests combining standard chemotherapy with radiation (chemoradiotherapy) plus two additional drugs, toripalimab and surufatinib, for people with limited-stage small cell lung cancer. The goal is to see if this combination improves outcomes.
Guangzhou, GuangdongAges 18–75 - NCT06721949RecruitingPhase 2/Phase 3
Taurine for long COVID symptoms
This trial tests if taking taurine, a natural amino acid supplement, can help reduce lingering symptoms of COVID-19 that last for months. If you have had COVID-19 and still have symptoms like fatigue or brain fog for at least 2 months after 3 months from your infection, this study might be for you.
Edmonton, AlbertaAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.