Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,348 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2836
- Phase 1458
- Phase 3420
- Phase 1/Phase 2310
- Phase 4212
- Phase 2/Phase 364
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer183
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease86
- Chronic Obstructive Pulmonary Disease (COPD)77
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center34
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California384
- Alabama176
- Arizona154
- Florida121
- Massachusetts120
- Maryland114
- New York113
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,348 total
- NCT07708116RecruitingPhase 1
First human trial of CTX-187 for healthy people and those with chronic infection
This trial tests a new drug called CTX-187 in two groups: healthy volunteers (Parts A and B) and people with chronic lung infection from bronchiectasis (Part C). It helps find the right dose and checks safety.
GroningenAges 18–65 - NCT07710820Recruiting
Can a heated tobacco product help you stop smoking?
This study tests whether having access to a heated tobacco product (a device that heats tobacco, not burns it) helps current cigarette smokers quit smoking. You'll try four different flavors over a week and then continue using one you like.
Brandon, FloridaAges 21–65 - NCT07709390RecruitingEarly Phase 1
Lidocaine gel on breathing tube for surgery
This trial tests whether putting lidocaine gel on the breathing tube before surgery can reduce post-operative sore throat and coughing. It aims to make recovery more comfortable for patients having general anesthesia.
Columbus, OhioAges 18–90 - NCT07711964RecruitingPhase 4
Finding the best steroid dose for ARDS patients on a ventilator
This trial tests different doses of corticosteroids to find the best one for people with acute respiratory distress syndrome (ARDS) who are on a breathing machine. It aims to improve recovery while reducing side effects.
TaipeiAges 18 years+ - NCT07711691Recruiting
Lung cancer screening study for current/former smokers
This study aims to help people who qualify for lung cancer screening actually get screened. It tests a program to remind and support you to schedule a low-dose CT scan.
Anaheim, CaliforniaAges 50–80 - NCT07707271Recruiting
Continuous vs. interval exercise for COPD
This trial compares two types of exercise training—steady moderate exercise versus short bursts of higher intensity—to see which is more helpful for people with COPD. It aims to find a better way to improve your breathing and fitness.
Thessaloniki, ExohiAges Any age - NCT07709182Recruiting
Guided breathing machine settings for weaning off ventilation
This trial compares two ways of adjusting the breathing machine to help patients come off it more smoothly. It uses a special measurement (airway occlusion pressure) to guide settings, which may help you breathe on your own faster.
Tanta, Al GharbiaAges 21 years+ - NCT07713914RecruitingPhase 4
Triple therapy vs sildenafil dose increase for PAH
This study compares two approaches for people with PAH whose current treatment (a combination of sildenafil and an endothelin receptor antagonist) needs to be stepped up. Half the participants will add a third medicine (iloprost or selexipag), while the other half will increase their sildenafil dose. The goal is to see which strategy works better for improving symptoms and lowering risk.
São Paulo, São PauloAges 18 years+ - NCT07708779RecruitingPhase 1
Inhaled isoniazid for tuberculosis treatment
This trial tests inhaled isoniazid (medicine) given through a nebulizer to see how well it works and how safe it is. It's for people being treated for tuberculosis.
GroningenAges 18 years+ - NCT07708870Recruiting
Nurse-led support for older adults with advanced lung cancer
This study tests a nurse-led support program for older adults (65+) with advanced lung cancer and their main family caregiver. The goal is to see if special help from a nurse can improve quality of life for both you and your caregiver.
Taipei, TaipeiAges 18 years+ - NCT07707245Recruiting
Finding biomarkers in lung disease and lung cancer
This trial studies blood and tissue samples from people with COPD, IPF, or lung cancer to find markers that can help diagnose and predict these conditions. It aims to discover why some lung diseases progress to cancer.
Milan, MilanAges 18 years+ - NCT07714863Recruiting
Can machine learning predict ABPA recurrence?
This study uses a computer model to see if it can predict when ABPA (a lung condition) might come back. If you have ABPA and are stable after treatment, this could help doctors monitor you better.
Jinan, ShandongAges 18 years+ - NCT07714525RecruitingPhase 2
Steroid nanocapsules after nasal surgery
This trial tests whether a new form of steroid (triamcinolone) delivered in tiny capsules can improve healing after common nasal surgeries for chronic sinusitis or nasal polyps.
Minya, Menia GovernorateAges 18–60 - NCT07713264Recruiting
Outdoor workers' safety study in California
This study listens to outdoor workers and community members in three California counties to understand safety needs. Participants will use a smartphone app or a provided phone to share what they see in their community.
Stanford, CaliforniaAges 18 years+ - NCT07713498Enrolling by invitation
Lowering inhaled steroids for tezepelumab-treated asthma patients
This trial looks at whether people with severe asthma who are taking the biologic tezepelumab can safely reduce their use of inhaled corticosteroids (ICS). It aims to see if reducing or stopping ICS affects asthma symptoms or flare-ups.
Rotterdam, South HollandAges 18 years+ - NCT07706595Enrolling by invitation
Nasal nerve treatment for chronic rhinitis
This trial compares two methods of a procedure that targets nasal nerves to reduce chronic rhinitis symptoms. It may help people whose rhinitis is not caused by allergies.
La Jolla, CaliforniaAges 18 years+ - NCT06642285Recruiting
Preventing nasal injuries in preterm babies on breathing support
This study tests if using special care steps can prevent nose sores in preterm babies who need breathing support through a mask or nasal prongs. It may help protect your baby's delicate nose from injury.
Kafr ash Shaykh, Kafr el-Sheikh GovernorateAges 7 months–9 months - NCT06637345Recruiting
Mesothelioma radiotherapy side effect study (MESORTIBO)
This study looks for markers in the blood that can predict side effects in patients with pleural mesothelioma who receive high-dose radiation. If you've had chemotherapy and are getting or have gotten high-dose radiation to the whole chest, researchers want to see if they can identify who is at higher risk of side effects.
Aviano, PordenoneAges 18 years+ - NCT06636955Recruiting
Bronchiolitis viruses after nirsevimab in infants
This study looks at how well the new nirsevimab vaccine works against bronchiolitis in babies. If your infant has their first bout of bronchiolitis and gets a nose swab, they may be able to help researchers understand how the virus spreads and how to better protect other babies.
RouenAges birth–1 year - NCT04605146Recruiting
Telemonitoring to manage side effects from immunotherapy
This trial tests whether using home digital monitoring (telemonitoring) can help people with melanoma, lung, or kidney (renal) cancer manage side effects while on immunotherapy. It may help catch side effects earlier and support you during treatment with nivolumab plus ipilimumab or nivolumab alone.
BronAges 18 years+ - NCT06302985Recruiting
Inhaled dye for lung malformations in children
This trial tests a new way to use a dye called ICG (indocyanine green) that is inhaled like a mist. It may help doctors see and treat congenital lung malformations in children more clearly.
Wuhan, HubeiAges 3 months–14 years - NCT06644820Recruiting
Spontaneous pneumothorax study at Sohag University
This trial looks at patients who have a spontaneous pneumothorax (a collapsed lung that happens without injury or medical procedure). It aims to understand their condition and outcomes.
SohagAges 18 years+ - NCT05501665RecruitingPhase 1/Phase 2
Adaptive radiation plus pembrolizumab for stage IV lung cancer
This trial tests a personalized (“adaptive”) radiation plan combined with pembrolizumab, and possibly chemotherapy, for advanced stage IV lung cancer. It aims to improve cancer control while carefully managing side effects, including in patients with certain brain metastases.
Nashville, TennesseeAges 18 years+ - NCT07704333RecruitingPhase 1
Imaging test for invasive mold infections
This study tests a new imaging agent that may help doctors see mold infections in the body. It involves healthy volunteers and people with mold infections, and aims to improve how these infections are detected and monitored.
Bethesda, MarylandAges 18–100
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,348 recruiting pulmonology studies from the U.S. registry right now, out of 9,933 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.