Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2848
- Phase 1470
- Phase 3423
- Phase 1/Phase 2310
- Phase 4207
- Phase 2/Phase 367
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer179
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Riphah International University34
Where studies are running
- California389
- Alabama174
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT07241286Enrolling by invitation
Enhanced Recovery Program for Kids After Lung Surgery
This trial tests a program to help children recover faster after lung surgery. The program focuses on improving recovery and reducing hospital stays.
Taipei, TaiwanAges birth–18 years - NCT07241208Recruiting
Comparing two ways to place breathing tube for lung surgery
This study compares two methods to insert a special breathing tube (double-lumen tube) for lung surgery. One method uses a camera on a flexible scope (fiberoptic bronchoscopy) and the other uses a video laryngoscope. Your participation could help doctors know which method works better.
SeoulAges 19 years+ - NCT07532811Recruiting
How Lungs Distribute Air and Blood in Critically Ill Children
This pilot study uses a special belt around the chest to measure how air and blood are distributed in the lungs of children on breathing machines in the intensive care unit. The goal is to better understand lung function in critically ill children.
Bron, FranceAges Up to 12 years - NCT07056075Recruiting
Preventing oxygen drops during ERCP
This trial tests two ways to prevent drops in oxygen levels during ERCP: one uses a special face mask to keep your airway open, and the other monitors your exhaled carbon dioxide. If you qualify, it could help make your procedure safer.
GrazAges 18–99 - NCT06257329Recruiting
Studying severe COPD flare-ups in the ICU
This trial is looking at patients with a serious worsening of their chronic obstructive pulmonary disease (COPD) who need intensive care. It aims to gather information to help improve treatment for these severe episodes.
Le ChesnayAges 40 years+ - NCT07638293Recruiting
High-Flow Oxygen Therapy Weaning Protocols for Respiratory Failure
This trial compares two different approaches to gradually reducing high-flow nasal oxygen therapy (a breathing support treatment delivered through your nose) in patients with acute respiratory failure. The goal is to find the best way to safely stop this treatment and transition you to breathing on your own.
Milan, LombardyAges 18 years+ - NCT07031986Recruiting
Lung surgery study for people with obesity
This trial compares two devices (bronchial blockers vs. double-lumen tubes) for one-lung ventilation during lung cancer surgery in people with obesity. It aims to find which method works better for this group.
Palma de Mallorca, Balearic IslandsAges 18–90 - NCT06228209Recruiting
Palliative care for advanced heart failure or cancer
This study tests whether adding a palliative care specialist to your regular care team can improve your quality of life if you have advanced heart failure or advanced lung or certain gastrointestinal cancers. It is for people who have been in the hospital recently and live in Manhattan.
New York, New YorkAges 18 years+ - NCT06751849RecruitingPhase 2
Vaccine, immunotherapy, and radiation for advanced lung cancer
This trial tests a combination of a personalized cancer vaccine, an immunotherapy drug (PD-1 inhibitor), and radiation therapy for people with advanced non-small cell lung cancer that has gotten worse after at least two prior treatments. The goal is to see if this approach can help shrink tumors or slow cancer growth.
Nanchang, JiangxiAges 18–70 - NCT07717801Recruiting
Breathing retraining for combat athletes
This study tests if a special breathing retraining program helps combat athletes who have trouble breathing properly during sport. It may improve how well you move and perform.
TainanAges 18–50 - NCT06082037RecruitingPhase 3
Testing belumosudil for chronic lung allograft dysfunction after transplant
This trial tests an oral medication called belumosudil for people with chronic lung allograft dysfunction (CLAD) after a double lung transplant. It may help slow the decline in lung function.
Birmingham, AlabamaAges 18 years+ - NCT06706492Recruiting
Muscle oxygen and frailty in kidney transplant patients
This study looks at how well muscles use oxygen and how frailty affects kidney transplant recipients, especially those with weak breathing muscles. It may help understand why some patients feel more tired or weak after transplant.
AnkaraAges 18–65 - NCT07687303Recruiting
Ventilator modes and stomach tube tolerance in ICU patients
This study looks at how different ventilator settings affect pressure in the belly and how well patients tolerate a feeding tube. It may help doctors choose the best ventilator mode for you.
DamanhūrAges 18–60 - NCT06739928RecruitingPhase 2
Irinotecan liposome with immunotherapy for extensive-stage small cell lung cancer
This trial tests a combination of irinotecan liposome (a chemotherapy) or etoposide with adebrelimab (an immunotherapy) and carboplatin for people with extensive-stage small cell lung cancer who haven't had prior treatment. It aims to see if these combinations are safe and effective.
Guangzhou, GuangzhouAges 18–70 - NCT07559786RecruitingPhase 2
Adebrelimab after chemo-radiation for limited-stage small cell lung cancer
This trial tests whether the drug adebrelimab (a type of immunotherapy) can help prevent your lung cancer from coming back after you finish chemotherapy and radiation. It is for people with limited-stage small cell lung cancer (cancer found only in one lung and nearby lymph nodes) that did not grow during initial treatment.
Zhengzhou, HenanAges 18–75 - NCT07686315Recruiting
Safer breathing with advanced monitoring on a ventilator
This trial is testing a new way to monitor your breathing while you are on a ventilator, to make it safer. It is for people who need a ventilator for reasons other than lung failure, like after a coma, injury, or severe infection.
Milan, LombardyAges 18 years+ - NCT05844891Recruiting
Telehealth follow-up for children with asthma after an ER visit
This study tests whether telehealth check-ins and asthma education after an emergency room visit can help children control asthma better at home. It may help reduce repeat flare-ups by improving daily asthma care and monitoring.
Rochester, New YorkAges 3–12 - NCT06734702RecruitingPhase 3
Immunotherapy before chemo-radiation for advanced lung cancer
This trial tests a new approach for people with stage III lung cancer that cannot be removed with surgery. You would receive immunotherapy (to help your immune system fight cancer) plus chemotherapy first, then standard chemo-radiation, and finally more immunotherapy. The goal is to see if this sequence works better than standard treatment.
Guangzhou, GuangdongAges 18–75 - NCT06487273Recruiting
SIMEOX device for mucus clearance at home in bronchiectasis
This study tests a home-use device called SIMEOX, which helps clear mucus from your lungs. It is for adults with bronchiectasis (not cystic fibrosis) who have frequent lung infections.
AbbevilleAges 18 years+ - NCT07541521Recruiting
Robot-Assisted Lung Surgery After Immunotherapy for Lung Cancer
This trial tests whether combining immunotherapy with chemotherapy before robot-assisted lung surgery improves outcomes for patients with stage II–III non-small cell lung cancer. The goal is to shrink the tumor before surgery and then remove it completely using minimally invasive robotic techniques.
Fuzhou, FujianAges Any age - NCT07545642Recruiting
Body Position and Oxygen Levels After Endoscopy
This study tests whether lying on your side versus on your back helps maintain better oxygen levels during and after a stomach/intestine viewing procedure. The trial includes patients with lung conditions to see what works best for different people.
Yinchuan, NingxiaAges 18 years+ - NCT07543380RecruitingPhase 3
RSV vaccine safety and immune response in high-risk adults
This study tests a new RSV vaccine designed to protect adults with chronic health conditions from severe RSV disease (a respiratory infection). Researchers will monitor how safe the vaccine is and how well your immune system responds to it.
Tsuchiura, IbarakiAges 18–59 - NCT07204990Recruiting
Swapping breathing tubes before waking for safer recovery
This study looks at whether replacing a breathing tube (endotracheal tube) with a mask-like device (laryngeal mask airway) before the child wakes up from anesthesia can make recovery smoother and safer.
Winston-Salem, North CarolinaAges birth–16 years - NCT07525518Enrolling by invitation
Okami Medical Device Patient Registry
This is a registry—a database that tracks patient outcomes—for people receiving Okami Medical devices. By joining, you help doctors understand how well these devices work and whether they're safe over time.
Aurora, ColoradoAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,521 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.