Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2848
- Phase 1470
- Phase 3423
- Phase 1/Phase 2310
- Phase 4207
- Phase 2/Phase 367
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer179
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Riphah International University34
Where studies are running
- California389
- Alabama174
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT07199881Recruiting
Breathing effort study after major abdominal surgery
This study checks how your breathing effort changes with different levels of breathing support from the ventilator after major abdominal surgery. It helps doctors find the best settings to help you breathe comfortably while you recover.
Bangkok, BangkoknoiAges 18 years+ - NCT07559591Recruiting
High-Flow Oxygen to Help Breathing Tube Patients
This study tests whether high-flow oxygen through a breathing tube helps patients recover faster after tracheostomy (a surgical opening in the windpipe). If you're in the ICU with a tracheostomy and nearly ready to breathe on your own, this trial may help you transition off the ventilator more smoothly.
RiyadhAges 18 years+ - NCT07198217RecruitingPhase 2
Chemo, radiation, and immunotherapy for lung cancer
This trial tests a combination of platinum-based chemotherapy, large fractionated radiotherapy, and the immunotherapy drug tislelizumab for people with stage IIIB to IV non-squamous non-small cell lung cancer. It aims to see if this approach can help control the cancer without certain gene mutations.
Zibo, ShandongAges 18–75 - NCT07612722Recruiting
Smaller vs. larger lung surgery after immunotherapy and chemotherapy
This trial compares two surgical approaches for advanced lung cancer (stage IIA-IIIB) after patients have already received immunotherapy and chemotherapy. Researchers want to see if removing a smaller portion of the lung (sub-lobectomy) works as well as removing an entire lobe (lobectomy), potentially reducing side effects while fighting cancer.
Guangzhou, GuangdongAges 18–75 - NCT07718295Recruiting
High-flow oxygen vs face mask for brain oxygen during sedation
This study compares two ways of giving oxygen (high-flow nasal oxygen vs a face mask) to see which one keeps brain oxygen levels more stable during procedures done with sedation. If you are having a planned procedure with sedation in a non-operating room setting, this trial might help improve your safety.
Elâzığ, ElâzığAges 18 years+ - NCT06220526Recruiting
Comparing needles for chest lymph node biopsy in sarcoidosis
This trial compares two types of needles used during a breathing-tube biopsy (EBUS-TBNA) to see which one works better for diagnosing sarcoidosis in people with enlarged chest lymph nodes.
Toronto, OntarioAges 18 years+ - NCT07536984Enrolling by invitation
Personalized Oxygen Levels for Breathing Machine Patients
This study tests whether adjusting oxygen levels on a breathing machine (ventilator) to match each patient's individual needs improves outcomes. Doctors will carefully monitor your oxygen levels and see how different targets affect your recovery.
Nashville, TennesseeAges 18 years+ - NCT07192575Recruiting
Preventing lung problems after laparoscopic liver surgery
This trial tests if special breathing exercises before surgery can help prevent lung complications after laparoscopic (keyhole) liver surgery. It may benefit you by reducing your risk of pneumonia or other breathing issues after the procedure.
KuopioAges 18 years+ - NCT07191080Enrolling by invitation
Using advanced genetic testing to diagnose hard-to-find respiratory infections
This study uses a powerful genetic test (next-generation sequencing) to find the cause of respiratory infections when standard tests fail. It may help identify hard-to-detect viruses, bacteria, or fungi in your lung or airway samples.
Nantong, JiangsuAges 18 years+ - NCT07060378Recruiting
Contrast Dye for Better Lung Biopsy
This trial tests whether using a special contrast dye during an ultrasound-guided biopsy (EBUS) makes it easier to see and sample lung tumors or swollen lymph nodes. It may help doctors get more accurate tissue samples with fewer tries.
Shanghai, Shanghai MunicipalityAges 18–90 - NCT07188480Recruiting
DNA and RNA testing for advanced lung cancer
This study tests a new way to analyze DNA and RNA from lung tumor samples taken during a bronchoscopy. It aims to find genetic changes that could help guide treatment for people with advanced non-small cell lung cancer.
Bologna, BolognaAges 18 years+ - NCT07063732Recruiting
Ketone drink, high altitude, and brain blood flow during exercise
This trial tests whether a ketone monoester supplement affects brain blood flow and exercise performance at high altitude. It may help us understand how to support brain function during altitude exposure.
Bishop, CaliforniaAges 18–35 - NCT07199517Recruiting
Helping smokers who aren't ready to quit
This study tests whether switching to a less harmful nicotine product (like a nicotine pouch or e-cigarette) can help people who are not ready to quit smoking reduce their health risks. You would be given a sample of a harm reduction product to try, and researchers will check how it affects your smoking habits.
Philadelphia, PennsylvaniaAges 21 years+ - NCT06311162Recruiting
Early help for kids exposed to smoke at home
This study tests a digital program to help families with young children reduce their exposure to second-hand smoke. It aims to support parents who smoke and are interested in creating a healthier home environment.
BernAges Up to 5 years - NCT07048275Enrolling by invitation
Virtual reality training for caregivers of children with pneumonia
This trial tests whether a virtual reality (VR) training tool can help caregivers learn chest tapping (percussion) for children with pneumonia, reduce caregiver stress, and improve teaching. If you are a caregiver for a child with pneumonia and meet the health and language requirements, you may be able to join.
YuanlinAges Up to 17 years - NCT07191002Recruiting
Choosing the right double-lumen tube size for lung surgery
This trial tests different formulas to predict the correct size of a double-lumen breathing tube used during lung surgery. It aims to make anesthesia safer and more effective for patients.
AnkaraAges 18–80 - NCT07585357Recruiting
Mobile app to help young smokers quit
This study tests a smartphone app that uses your location and daily habits to help you quit smoking. Researchers will send you personalized tips and support for 44 days to see if this approach helps you successfully stop smoking.
Baltimore, MarylandAges 18–40 - NCT07073976Recruiting
Predicting success of coming off the breathing machine using heart ultrasound
This study uses an ultrasound of the heart (echocardiogram) to check how well the right side of your heart is working. The goal is to see if that can help predict whether you will successfully come off the breathing machine.
Istanbul, IstanbulAges 18 years+ - NCT07077174Recruiting
Permissive lung-protective ventilation for critically ill patients on a breathing machine
This trial tests whether a more lenient approach to lung-protective ventilation can improve outcomes for patients who need a breathing machine (ventilator) in the intensive care unit. It aims to find a balance that is safer for the lungs while still being effective.
AlmeloAges 18 years+ - NCT07087223RecruitingPhase 1/Phase 2
Study of vebreltinib plus furmonertinib for NSCLC with c-Met amplification
This trial tests a combination of two targeted therapies (vebreltinib and furmonertinib) for people with a specific type of advanced non-small cell lung cancer (NSCLC) that has a change called c-Met amplification and has stopped responding to earlier EGFR-targeted treatment. It aims to see if adding vebreltinib can help control the cancer.
Neimeng, NeimengAges 18 years+ - NCT07093125Recruiting
Rehabilitation for ICU patients on a breathing machine
This trial is studying rehabilitation practices for people in the ICU who need a breathing machine (ventilator) for at least 48 hours. It aims to improve recovery and care for critically ill patients.
Genova, ItalyAges 16–100 - NCT07534033RecruitingPhase 2
Probiotic LR607 for newly diagnosed lung cancer
This study tests whether a probiotic supplement (LR607) can help patients with newly diagnosed non-small cell lung cancer—a common type of lung cancer. Probiotics are beneficial bacteria that may help your immune system fight cancer alongside standard treatments.
GuangzhouAges 18–80 - NCT07046910RecruitingPhase 2
MRI to detect lung rejection after transplant
This study uses a special MRI scan (called hyperpolarized gas MRI) to check for signs of lung rejection after a transplant. The goal is to see if the MRI can help detect rejection earlier and more safely than standard bronchoscopy alone.
Charlottesville, VirginiaAges 18–80 - NCT06213168Recruiting
CPAP plus high-flow oxygen vs oxygen alone for breathing failure
This study tests whether adding a breathing machine (CPAP) to high-flow oxygen can help people with sudden breathing failure more than high-flow oxygen alone. It is for adults recently admitted to the ICU with low oxygen levels.
AmiensAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,521 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.