Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2848
- Phase 1470
- Phase 3423
- Phase 1/Phase 2310
- Phase 4207
- Phase 2/Phase 367
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer179
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Riphah International University34
Where studies are running
- California389
- Alabama174
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT05766124RecruitingPhase 2/Phase 3
Lower-dose clot-busting medicine for infected chest fluid
This study tests whether a lower dose of alteplase (a clot-busting medicine) given into the chest can improve healing of infected pleural fluid when drainage is incomplete. It may help reduce dosing-related side effects while still helping clear the infection-related fluid.
Hong Kong, Hong KongAges 18 years+ - NCT07382063Enrolling by invitation
Nerve block effects on diaphragm in kids having arm surgery
This study tests a special numbing shot (nerve block) around the shoulder to see how it affects the muscle that helps kids breathe (the diaphragm) during and after arm surgery. It may help doctors choose safer pain methods for school-aged children.
ShanghaiAges 6–12 - NCT07235683RecruitingPhase 4
Stronger CMV treatment for lung transplant recipients
This trial tests adding a drug called letermovir to standard antiviral therapy for lung transplant patients with CMV infection. The goal is to see if the combination helps clear the virus faster and more effectively.
Toronto, OntarioAges 18 years+ - NCT06832098RecruitingPhase 3
Nicotine patch plus spray vs reducing nicotine to quit vaping
This study tests two ways to help you stop vaping: using a nicotine patch and mouth spray, or slowly lowering the nicotine in your vape. If you live in New Zealand, vape regularly, and are ready to quit, this trial may help you find the best method.
AucklandAges 16 years+ - NCT07342803RecruitingPhase 2
LP-003 injection for allergic asthma
This trial tests an injection called LP-003 for people with allergic asthma that is not well controlled by current inhalers and other medications. It aims to see if the drug can improve asthma control and reduce flare-ups.
ShanghaiAges 18–75 - NCT06853483Enrolling by invitation
School program to help parents quit smoking
This trial tests if a school-based program can help parents stop smoking. If you are a parent who smokes at least one cigarette a day and your child is in primary 4 (4th grade), this program may offer support to help you quit.
Wuhan, HubeiAges Any age - NCT07216144Enrolling by invitation
Lung cancer screening outreach in at-risk New Yorkers
This study helps patients at Ryan Health who are at risk for lung cancer get a free lung cancer screening (a low-dose CT scan). If you're between 50 and 80, smoke or used to smoke, and haven't had this scan in the past year, you may be able to participate.
New York, New YorkAges 50–80 - NCT06447402RecruitingPhase 3
Inhaled Amphotericin B for Chronic Aspergillosis Maintenance
This study compares two inhaled treatments (amphotericin B vs. saline) to see which one works better as maintenance therapy for people with chronic pulmonary aspergillosis. It aims to find a convenient way to keep the infection under control after initial treatment.
ChandigarhAges 18 years+ - NCT07218939Recruiting
Collecting extra samples during lung procedures
This trial collects extra samples (like tissue or fluid) that are left over from your routine lung procedure. It helps researchers study lung health without any extra risk to you.
Houston, TexasAges 18 years+ - NCT05692999RecruitingPhase 3
Maintenance pembrolizumab dose study for non-squamous lung cancer
This Phase 3 trial tests two maintenance schedules (“usual” dose versus a lower dose) of pembrolizumab after your initial chemotherapy with pembrolizumab. It aims to see if the lower dose works well enough to control cancer while possibly reducing side effects.
NamurAges 18 years+ - NCT07213765RecruitingPhase 4
Short-term antibiotics for MAC lung disease
This trial tests whether a shorter course of antibiotics works for people with a specific type of lung infection caused by Mycobacterium avium complex (MAC). It aims to find a treatment that is just as effective but easier to complete.
Hefei, AnhuiAges 18–75 - NCT07211997Recruiting
FebriDx test for fever and cold symptoms in children
This study tests a finger-prick blood test (FebriDx) to see if it can quickly tell whether a child's fever and cold symptoms are caused by a bacterial or viral infection. If it works, it could help doctors decide whether antibiotics are needed.
Colton, CaliforniaAges 2–11 - NCT07468006Recruiting
Comparing carbon dioxide measurements in critically ill children
This trial tests if a sticker on the skin can accurately measure carbon dioxide levels in the blood, reducing the need for needle sticks in children in the intensive care unit.
BrnoAges 1–18 - NCT07208500Recruiting
Arm cuff treatment before surgery to protect lungs in older adults
This study tests if a simple, non-invasive treatment (briefly inflating a blood pressure cuff on your arm) before surgery can reduce lung complications in older adults having non-heart, non-lung surgery. It may help protect your lungs during and after the operation.
ShanghaiAges 65 years+ - NCT07207278Recruiting
Genetics and immune study of lung signet ring cell cancer
This research study is looking at the unique genetic makeup and immune features of a rare type of lung cancer called signet ring cell carcinoma. By studying tumor samples and medical data, researchers hope to find better ways to understand and eventually treat this cancer.
Hangzhou, ZhejiangAges 18–85 - NCT05987345Recruiting
Pulsed electric field therapy for advanced lung cancer after immunotherapy
This trial tests a new treatment called pulsed electric field therapy for people with advanced lung cancer (stage III or IV) that has not responded to first-line immunotherapy. It uses targeted electrical pulses to destroy tumor cells, and may be an option for those who still have other measurable tumors.
Guangzhou, GuangdongAges 22 years+ - NCT07200206Recruiting
Safety tracking study for Beyfortus in Korean children
This study monitors the safety of Beyfortus (nirsevimab) in children up to 2 years old who have already received it as prescribed. It helps make sure the medicine is safe and works well in real-world use.
Hwaseong-si, Gyeonggi-doAges birth–2 years - NCT06091085RecruitingPhase 1/Phase 2
Acetazolamide for sleep apnea in untreated patients
This study tests a medicine called acetazolamide to see if it can improve how your brain controls breathing during sleep apnea. If you have sleep apnea and are not using treatment, you might be able to join.
Boston, MassachusettsAges 21–80 - NCT06050980RecruitingPhase 1
Study of HSK40118 for advanced lung cancer with EGFR mutation
This trial tests a new drug, HSK40118, for people with advanced non-small cell lung cancer (NSCLC) that has an EGFR mutation and has been treated with certain EGFR-targeted therapies before. The goal is to see if this drug can help when other treatments stop working.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07191509Recruiting
Understanding breathing after tracheostomy removal
This study looks at how your breathing changes after removing a tracheostomy tube, using a valve and simple breathing tests. It may help doctors better plan your recovery.
BeijingAges 18 years+ - NCT07188350Recruiting
Electrical muscle stimulation for patients on a breathing machine
This trial tests whether low-level electrical pulses to the leg muscles can help prevent weakness in patients who need a breathing tube (ventilator) for more than 48 hours. It aims to see if this treatment helps patients recover faster.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07184814Recruiting
Takayasu's arteritis with lung artery involvement study
This study looks at people with Takayasu's arteritis that also affects the lungs' blood vessels. Researchers want to understand the disease's behavior and outcomes over time.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07184528Recruiting
Endobronchial valves and blood patch for air leaks
This trial tests a two-step procedure that uses small valves and a blood patch to close persistent air leaks in the lung. It could be an option for people who cannot have or don't want surgery.
Boston, MassachusettsAges 18 years+ - NCT06419036Enrolling by invitation
Using medical devices to monitor COPD at home
This study tests whether wearable medical devices can help monitor your COPD symptoms at home. You will use a smartphone app and a small chest patch to track your breathing, which may help you and your doctor better manage your condition.
GlasgowAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,521 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.