Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,618 recruiting studies in this area right now.
By phase
- Not applicable4,293
- Phase 2848
- Phase 1470
- Phase 3423
- Phase 1/Phase 2310
- Phase 4207
- Phase 2/Phase 367
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer179
- Non-small Cell Lung Cancer171
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer109
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Pneumonia78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Riphah International University34
Where studies are running
- California389
- Alabama174
- Arizona154
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas89
- Pennsylvania84
- Colorado71
Recruiting studies6,618 total
- NCT06513091Recruiting
National lung transplant recipient registry study
This study collects information from all lung transplant recipients in the United States to track their health and outcomes over time. It helps doctors learn how to improve care for people who have had a lung transplant.
Phoenix, ArizonaAges Any age - NCT07181499RecruitingPhase 2
Chemotherapy with befotertinib for resistance to targeted lung cancer drugs
This trial tests a combination of chemotherapy and a targeted drug (befotertinib) for people with non-small cell lung cancer whose cancer has stopped responding to a common type of targeted therapy. It aims to see if this new sequence can help overcome resistance.
Guangzhou, GuangdongAges 18 years+ - NCT06547463Recruiting
Nasal airflow and sleep in tracheostomy patients
This study looks at how breathing through your nose affects sleep quality for patients with a tracheostomy who are on a ventilator at night. It involves a sleep test to measure your sleep patterns and breathing, which could help improve your care.
Paris, ParisAges 18 years+ - NCT06841731RecruitingPhase 2
Testing a new antibiotic for hospital-acquired pneumonia
This trial tests a new antibiotic called HRS-8427 for adults with bacterial pneumonia that started in the hospital or while on a ventilator. It may be an option if you need IV antibiotics and haven't already received long-term treatment for this infection.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06501209Enrolling by invitation
Counseling to help you quit tobacco
This study tests if a special counseling method (called 5A-5R) helps people quit tobacco. If you are an adult who uses tobacco daily and wants to quit, you may be able to join.
DhakaAges 18 years+ - NCT07630662Recruiting
Breathing Muscle Function and Ventilator Weaning Success
This study looks at whether testing the strength and function of your breathing muscles (diaphragm and chest wall muscles) can predict whether you're ready to come off a ventilator (breathing machine). The goal is to help doctors make better decisions about when patients are ready to breathe on their own.
CairoAges 18 years+ - NCT07170085Recruiting
Positioning for babies with breathing problems
This trial tests if different body positions help babies under 1 year old with breathing problems breathe better while on oxygen support (High-Flow or CPAP).
OdenseAges Up to 1 year - NCT07162935Recruiting
Cigarillo use study for young adults
This study looks at how young adults use cigarillos. You will smoke research cigarillos in a lab and answer questions. The goal is to understand cigarillo use to help with future regulation.
Oklahoma City, OklahomaAges 18–24 - NCT07168798Enrolling by invitation
Checking oxygen accuracy in kids
This study tests how well a new oxygen sensor (pulse oximeter) works on children in the cardiac intensive care unit. If your child already has an artery line placed for normal care, this sensor might give more accurate readings without any extra pokes.
Philadelphia, PennsylvaniaAges birth–12 years - NCT07156890Recruiting
Respiratory virus monitoring for health and animal workers
This research study tracks respiratory viruses in healthcare and animal workers. It aims to better understand how these viruses spread, which could help protect workers and the community.
Rotterdam, South HollandAges 18 years+ - NCT05794087Recruiting
Study of lung inflammation after ozone exposure
This trial studies how immune cells in the lungs respond after ozone exposure, to better understand lung injury. It may help researchers learn what drives inflammation and what could protect the lungs in the future.
Piscataway, New JerseyAges 18–40 - NCT06553911Recruiting
AI tools for diagnosing respiratory infections
This trial uses artificial intelligence (AI) to help doctors read X-rays or CT scans of people with respiratory infections. The goal is to see if AI can make diagnosis faster and more accurate.
ShanghaiAges 1–90 - NCT07638891RecruitingPhase 1
HDM2020 for Advanced Squamous Lung Cancer
This study tests a new drug called HDM2020 in patients with advanced squamous cell lung cancer (a specific type of lung cancer) that has stopped responding to standard treatments. The drug is designed to target cancer cells that have high levels of a specific protein called FGFR2b.
Guangzhou, GuangdongAges 18–75 - NCT07138027Recruiting
Asthma control study for kids at CHOP clinics
This study looks at ways to improve asthma care for children who have uncontrolled asthma. It tests how well different approaches work at CHOP pediatric clinics to help kids breathe better.
Philadelphia, PennsylvaniaAges 5–18 - NCT07130123Recruiting
Endotracheal suction during extubation in the ICU
This study compares different methods of suctioning the breathing tube during extubation (removal of the tube) in patients who have been on a ventilator for more than 48 hours. It aims to find the best way to clear the airway while taking the tube out.
Orléans, LoiretAges 18 years+ - NCT07129616Recruiting
Remote monitoring for childhood asthma
This study tests if remote monitoring tools can help manage asthma in children and young people. It aims to see if tracking symptoms and medication use from home improves care.
EdinburghAges 5–17 - NCT03694236RecruitingPhase 1/Phase 2
Durvalumab with chemoradiation before lung tumor surgery
This trial studies whether adding durvalumab (an immune therapy) to standard chemoradiation before surgery can improve outcomes for people with stage III, resectable lung cancer. It aims to help shrink the tumor and improve chances of successful treatment.
Seoul, SeoulAges 20 years+ - NCT07121517Recruiting
Predicting airway problems in children with tracheostomies
This study looks at children with tracheostomies to see if symptoms you or your doctor notice can predict airway problems found during a routine scope. Participation involves no extra procedures—just answering questions and giving permission to use information from that routine scope.
SolnaAges Up to 18 years - NCT05678166Recruiting
Testing a blood marker to predict worsening lung mycobacterial disease
This study checks whether a blood test called soluble programmed death-1 can help predict how nodular-bronchiectatic nontuberculous mycobacterial (NTM) lung disease will progress. Results may help doctors monitor patients more accurately and decide when to treat or follow more closely.
TaipeiAges 20 years+ - NCT07392086Recruiting
Comparing two types of ventilation during one-lung surgery
This trial compares two ways of helping you breathe during chest surgery: flow-controlled ventilation and volume-controlled ventilation. The goal is to see which method works better for oxygen and lung protection while one lung is temporarily deflated.
Ankara, YenimahalleAges 18–80 - NCT05798845RecruitingPhase 2
Toripalimab plus radiation before surgery for stage II–IIIA lung cancer
This trial studies whether adding toripalimab (an immunotherapy medicine) to radiation can improve outcomes for people with operable stage II to IIIA non-small cell lung cancer. It’s designed for cancers that can be fully removed with surgery, and it aims to see if this combination helps more than radiation alone/standard care.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07105436Recruiting
Testing Thopaz Device for Persistent Lung Air Leaks
This trial tests a device called Thopaz for people who have a stubborn air leak in the lung (an air leak that hasn't healed after 5 days of chest tube drainage). The study is for those who are already scheduled for a bronchoscopy to address the leak, and aims to see if Thopaz can help stop the leak faster.
Boston, MassachusettsAges 18 years+ - NCT07097961Recruiting
Rehab program for kids with lung damage after TB
This study tests a rehab program for children aged 6-17 who have lung damage from a past tuberculosis (TB) infection. The program uses mild-to-moderate physical activity to help improve their breathing and daily life.
KampalaAges 6–17 - NCT07199530Recruiting
D-dimer test for pneumonia severity and survival
This study looks at a blood test called D-dimer to see if it can predict how severe your pneumonia will be and how well you will recover. It helps doctors understand inflammation and survival in adults with community-acquired pneumonia.
CairoAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,618 recruiting pulmonology studies from the U.S. registry right now, out of 10,521 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.