Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,347 recruiting studies in this area right now.
By phase
- Not applicable4,045
- Phase 2834
- Phase 1458
- Phase 3422
- Phase 1/Phase 2311
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer415
- Asthma193
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD133
- Breast Cancer111
- Pulmonary Hypertension104
- COVID-1988
- Colorectal Cancer88
- NSCLC87
- Chronic Obstructive Pulmonary Disease85
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia69
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California383
- Alabama175
- Arizona154
- Florida121
- Massachusetts120
- Maryland114
- New York111
- Texas87
- Pennsylvania81
- Illinois73
Recruiting studies6,347 total
- NCT07542366Recruiting
Testing a new lung imaging method in ICU patients
This study tests whether a special imaging technique called EIT (electrical impedance tomography) combined with a safe contrast injection can measure blood flow in the lungs of patients on breathing machines. If it works, it could help doctors better manage critically ill patients.
Wuhu, AnhuiAges 18 years+ - NCT07535398Recruiting
Telehealth Exercise Program for High Lung Blood Pressure
This study tests whether people with elevated pressure in the blood vessels of the lungs can safely exercise at home using video sessions with therapists. It aims to see if remote rehabilitation can improve heart function and daily activity without requiring in-person visits.
Tokat ProvinceAges 18–65 - NCT07535437RecruitingPhase 1/Phase 2
New Drug Combination for Advanced Lung Cancer After Previous Treatment
This study tests a new combination of drugs (ivonescimab with either dato-DXd or osimertinib) for people with advanced lung cancer that has a specific EGFR gene mutation and has already been treated with other therapies. The goal is to see if this combination can help control the cancer better than current options.
Basking Ridge, New JerseyAges 18 years+ - NCT07536984Enrolling by invitation
Personalized Oxygen Levels for Breathing Machine Patients
This study tests whether adjusting oxygen levels on a breathing machine (ventilator) to match each patient's individual needs improves outcomes. Doctors will carefully monitor your oxygen levels and see how different targets affect your recovery.
Nashville, TennesseeAges 18 years+ - NCT07541638Recruiting
Early Lung Fibrosis Detection in Rheumatic Diseases
This study helps doctors identify early signs of lung scarring (fibrosis) in patients with autoimmune diseases like scleroderma, rheumatoid arthritis, and Sjögren's syndrome. By catching this early, researchers hope to better understand and treat these complications.
RomaAges 18–75 - NCT06749886RecruitingPhase 2
Tislelizumab plus chemo for advanced lung cancer after prior immunotherapy
This trial tests a drug called Tislelizumab (an immunotherapy) combined with chemotherapy for people with advanced NSCLC who have already been helped by a different immunotherapy. It's a second-line option for those who did well on their first immunotherapy but now need another treatment.
ShanghaiAges 18 years+ - NCT06749691RecruitingPhase 2
Liposomal irinotecan and apatinib for extensive-stage small cell lung cancer
This trial tests a combination of two drugs, liposomal irinotecan and apatinib, for people with extensive-stage small cell lung cancer (ES-SCLC) that has progressed after first or second line treatment. The goal is to see if this new combination can help shrink tumors or slow the cancer's growth.
Hangzhou, ZhejiangAges 18–75 - NCT06749860RecruitingPhase 2
Targeted drug combo for HER2-positive advanced lung cancer
This trial tests a combination of three drugs (Disitamab Vedotin, Tislelizumab, and Bevacizumab) for people with advanced non-small cell lung cancer that has a specific change in the HER2 gene or protein. The goal is to see if this combination can shrink tumors or slow the cancer's growth.
ShanghaiAges 18 years+ - NCT06752057Recruiting
Personalized vaccine plus immunotherapy and radiation for advanced lung cancer
This study tests a combination of a personalized vaccine made from your tumor's unique markers, a type of immunotherapy (PD-1 inhibitor), and radiation. The goal is to see if this mix can work better for advanced lung cancer that has progressed after initial treatment.
Nanchang, JiangxiAges 18–70 - NCT05681962Recruiting
Improving breathing support during flexible bronchoscopy
This trial studies how to give oxygen and breathing support during a flexible bronchoscopy (a camera test through the airways). It may help make the procedure safer and more comfortable by refining the way oxygen is managed during the test.
CatanzaroAges 18 years+ - NCT06752044Recruiting
Vaccine, immunotherapy, and radiation for advanced lung cancer
This trial tests a combination of a personalized vaccine (made from your tumor's unique markers), a drug that boosts your immune system (PD-1 inhibitor), and targeted radiation for people with advanced lung cancer that has progressed after initial treatment. The goal is to see if this combination can help shrink tumors or slow the cancer's growth.
Nanchang, JiangxiAges 18–70 - NCT06751849RecruitingPhase 2
Vaccine, immunotherapy, and radiation for advanced lung cancer
This trial tests a combination of a personalized cancer vaccine, an immunotherapy drug (PD-1 inhibitor), and radiation therapy for people with advanced non-small cell lung cancer that has gotten worse after at least two prior treatments. The goal is to see if this approach can help shrink tumors or slow cancer growth.
Nanchang, JiangxiAges 18–70 - NCT06751901RecruitingPhase 2
Vaccine, immunotherapy, and radiation for advanced lung cancer
This trial tests a combination of a personalized peptide vaccine, an immunotherapy drug (PD-1 inhibitor), and radiation for people with advanced non-small cell lung cancer whose disease has gotten worse after at least two standard treatments. It aims to see if this triple therapy can help control the cancer.
Nanchang, JiangxiAges 18–70 - NCT07531095RecruitingPhase 1
Combination drug trial for small cell lung cancer
This study tests three experimental drugs (tarlatamab, ZL-1310, and sometimes an immune-boosting drug) together to treat small cell lung cancer. The goal is to see if this combination can slow or shrink the cancer and help you live longer.
Goodyear, ArizonaAges 18–99 - NCT07525518Enrolling by invitation
Okami Medical Device Patient Registry
This is a registry—a database that tracks patient outcomes—for people receiving Okami Medical devices. By joining, you help doctors understand how well these devices work and whether they're safe over time.
Aurora, ColoradoAges 18 years+ - NCT07532265RecruitingPhase 2
Testing a New Drug for Hard-to-Control Asthma
This study tests whether a new drug called frevecitinib can help people with severe asthma that isn't well controlled even with strong inhaled steroid medications. The goal is to see if it reduces asthma attacks and improves breathing.
Lancaster, CaliforniaAges 18–75 - NCT07525375RecruitingPhase 2
Lung Function Study of Inhaled Glycopyrronium With BFF in Children With Asthma
This study tests whether adding a medication called glycopyrronium to a common asthma inhaler (BFF) helps children ages 4–12 breathe better. Researchers will measure lung function and compare two different doses of the added medication.
Bakersfield, CaliforniaAges 4–11 - NCT07526506RecruitingPhase 1
TRX-100 safety and how food affects it in healthy adults
This early-stage study tests a new drug called TRX-100 in healthy volunteers to see if it's safe and how the body processes it, especially when taken with food. The trial helps researchers understand the drug's basic safety profile before testing it in people with medical conditions.
Randwick, New South WalesAges 18–65 - NCT04754854Recruiting
Testing less blood recirculation during veno-venous ECMO
This trial studies whether a change in how a veno-venous ECMO machine works can reduce “blood recirculation” (blood returning to the circuit too quickly) in people with severe lung failure. It may help improve oxygen levels in adults whose ARDS is not responding to standard treatment.
BerlinAges 18 years+ - NCT07530302Recruiting
Better ways to adjust CPAP therapy when it isn't working well
This trial tests whether a wearable device called Sunrise can help doctors adjust your CPAP machine better than standard sleep tests. If your current CPAP isn't stopping all your breathing pauses, this study may help find the right adjustments for you.
GrenobleAges 18–85 - NCT07525427RecruitingPhase 2
New Tuberculosis Drug Study for Drug-Sensitive TB
This study tests a new tuberculosis drug called TBD09 combined with other TB medicines in people with newly diagnosed, drug-sensitive TB. The goal is to see if this combination works well and is safe.
Durban, BluffAges 18–65 - NCT07528274RecruitingPhase 2
Microwave ablation with immunotherapy for advanced lung cancer
This trial tests combining microwave ablation (heat treatment of tumors) with two drugs—tislelizumab (an immune-boosting drug) and docetaxel (chemotherapy)—for patients with advanced non-small cell lung cancer whose disease progressed after initial immunotherapy. The goal is to see if this combination can slow or shrink tumors better than standard treatment alone.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07529847Recruiting
Breathing Techniques to Help Asthma Control
This study compares two special breathing techniques—alternating which nostril you breathe through and a method called Buteyko breathing—to see which helps asthma patients breathe easier and improve lung function. You'll practice these techniques and we'll measure how well they work for you.
IslamabadAges 18–45 - NCT07527702Recruiting
Comparing suction pressures after lung cancer surgery
This study tests two different suction pressures used on chest tubes after lung cancer surgery to see which helps patients recover better. The goal is to find the safest and most effective way to remove fluid and air from the chest cavity after surgery.
SeoulAges 19 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,347 recruiting pulmonology studies from the U.S. registry right now, out of 9,965 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.