Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,629 recruiting studies in this area right now.
By phase
- Not applicable4,297
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2310
- Phase 4208
- Phase 2/Phase 368
Top conditions
- Lung Cancer425
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer180
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea156
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer86
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Ovarian Cancer74
- Acute Respiratory Distress Syndrome72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)40
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama174
- Arizona155
- Massachusetts128
- Florida117
- New York113
- Maryland110
- Texas90
- Pennsylvania84
- Colorado71
Recruiting studies6,629 total
- NCT06848881Recruiting
Freezing vs surgery for lung spots
This trial compares two treatments for slow-growing lung spots (GGNs): freezing the spot (cryoablation) versus removing it with surgery. It's for people whose spots are small, not yet widespread, and who are able to have either procedure.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07065318Recruiting
Exercise training for lung transplant candidates
This study compares two types of exercise programs (aerobic walking/cycling and high-intensity interval training) for people with interstitial lung disease who are waiting for a lung transplant. The goal is to see which type of exercise helps improve daily function and quality of life.
Ankara, AnkaraAges 18–64 - NCT07009509Recruiting
Yes-Can! program to prevent youth vaping
This study tests a program called YES-CAN! that aims to keep middle and high school students from starting to vape nicotine. If you are a student in grades 6-12, or an adult working in a school, you may be able to join.
Aurora, ColoradoAges 9 years+ - NCT06792617Enrolling by invitationEarly Phase 1
Exercise for people on ECMO life support
This study tests if gentle exercise in bed can help people on ECMO (a life-support machine for heart and lungs) get stronger and recover faster. It is for adults in the ICU who are stable enough to move safely.
San Antonio, TexasAges 18 years+ - NCT06125210Recruiting
Early treatment bundle to prevent ventilator dependence in kids
This study tests a set of early therapies (a 'bundle') for children on breathing machines to help them get off the machine sooner and avoid long-term dependence. It may be a good fit if your child is stable and doesn't have severe brain or spine problems.
Shanghai, Shanghai MunicipalityAges 4 weeks–18 years - NCT06441812RecruitingPhase 2
Long-term safety of a new asthma medicine
This trial tests a new medicine called SHR-1703 for people with eosinophilic asthma (a type of asthma with high levels of certain white blood cells). It looks at how safe the medicine is over time and if it helps control asthma attacks. You must already be using medium or high dose inhaled steroids plus another asthma medicine, and have had at least one asthma attack in the past year.
Chengdu, SichuanAges 18 years+ - NCT07042035Recruiting
A study of once-daily tacrolimus for new lung transplant patients
This trial tests a special form of tacrolimus (Envarsus) taken once daily to prevent organ rejection in people who recently received a first lung transplant. The study will follow patients for at least 12 months.
L'Hospitalet de Llobregat, BarcelonaAges 18 years+ - NCT07718451Recruiting
Using digital twins to help doctors learn bronchoscopy faster
This trial tests whether a training tool that uses CT scans to create digital copies of patients (digital twins) can help new doctors learn bronchoscopy faster. It may help trainees become skilled more quickly, which could lead to safer procedures for patients.
Beijing, Beijing MunicipalityAges 18–75 - NCT06459206Recruiting
Testing a smart ring's oxygen sensor during low oxygen levels
This study checks how well a special ring (EvieMED Ring) measures oxygen in your blood when oxygen levels are made very low in a controlled setting. It helps see if the ring is accurate for people with serious health conditions.
San Francisco, CaliforniaAges 18–49 - NCT07031024Recruiting
Quit smoking help in the hospital
This trial studies a program to help smokers quit, offered to anyone over 18 who smokes at least one cigarette (or equivalent) a day, regardless of their reason for visiting the hospital or other substance use. If you are a current smoker, you can join to get support for quitting.
Nice, Alpes MaritimesAges 18 years+ - NCT06101030Recruiting
Breathing exercise with or without a reminder device
This study tests whether a special reminder device helps people do their breathing exercises more often after surgery. You will use a breathing exercise tool (incentive spirometer) with or without a reminder that beeps or flashes to prompt you to use it.
Silver Spring, MarylandAges 18 years+ - NCT07710469Enrolling by invitation
Weighted blanket for comfort during vent weaning
This trial is testing whether a special weighted blanket can help you feel more calm and comfortable as doctors slowly reduce the support from your breathing machine. It's for people who are on a ventilator and ready to start the weaning process.
Boston, MassachusettsAges 18 years+ - NCT07304479Recruiting
Comparing two anesthetics for robotic surgery
This trial compares two types of anesthesia (sevoflurane and desflurane) during robotic abdominal surgery. It aims to find which one may be safer and better for your lungs.
AthensAges 18–87 - NCT07256821Recruiting
Finding the best breathing muscle training dose in the ICU
This trial tests different amounts of inspiratory muscle training (IMT) for patients who have a tracheostomy tube and are on a breathing machine in the intensive care unit. Researchers want to find the dose that helps most with recovery.
MarlowAges 18 years+ - NCT07309393Recruiting
Comparing two muscle relaxant reversal drugs after lung surgery
This trial tests two different medicines used to reverse muscle relaxation after lung surgery. It looks at which one helps you breathe better in the first hours after your procedure.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07724197Recruiting
Using a new imaging test to find blood clots in the lungs
This study tests a new, non-invasive imaging method called pulsatile electrical impedance tomography (EIT) to help diagnose and monitor acute pulmonary embolism (blood clots in the lungs). It may provide a faster or safer way to detect clots compared to standard CT scans, especially for patients who cannot have contrast dye.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06418087RecruitingPhase 2
Durvalumab plus chemotherapy for advanced LCNEC
This trial tests a combination of a new immunotherapy drug (durvalumab) with standard chemotherapy for people with a rare, advanced form of lung cancer called LCNEC. It aims to see if this combination can shrink tumors or slow the cancer’s growth better than chemotherapy alone.
Bologna, BOAges 18 years+ - NCT07224152RecruitingPhase 1/Phase 2
NBTXR3 plus radiation for inoperable lung cancer
This trial tests a new drug called NBTXR3, which makes cancer cells more sensitive to radiation. You'll get one injection of NBTXR3 into your lung tumor, followed by standard radiation. It is for people with early-stage non-small cell lung cancer who cannot have surgery.
Houston, TexasAges 18 years+ - NCT07672106Recruiting
Predicting breathing tube need after major surgery recovery
This study watches patients after major surgery to see which factors may increase the chance of needing a breathing tube again. It helps doctors better predict and prevent breathing problems in the intensive care unit.
Istanbul, ŞişliAges 18 years+ - NCT06115395Recruiting
Non-invasive ventilation for bronchoscopy
This trial uses a breathing mask (non-invasive ventilation) to help people who need a bronchoscopy. It aims to make the procedure safer and more comfortable for those with breathing problems.
Al MansurahAges 18–70 - NCT07222670RecruitingPhase 2
Study of INNA-051 to prevent viral respiratory illness in healthy adults
This trial tests whether INNA-051 can help prevent respiratory infections caused by viruses in healthy adults aged 18 to 45. It may be an option if you are at higher risk of catching such infections due to your living or work situation.
Baltimore, MarylandAges 18–45 - NCT07229599RecruitingPhase 1/Phase 2
MHB036C combined with other treatments for advanced lung cancer
This study tests a new drug called MHB036C combined with other anti-tumor treatments for people with advanced lung cancer or other solid tumors that have not responded to standard therapies. It aims to find a safe and effective dose and see if the combination can shrink tumors.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07330037RecruitingPhase 2
TIL plus immunotherapy for NSCLC without complete response after chemoimmunotherapy
This trial tests a new treatment for people with non-small cell lung cancer (NSCLC) that was removed by surgery but did not completely disappear after pre-surgery chemoimmunotherapy. The treatment combines your own tumor-fighting cells (L-TIL, grown from your tumor) with an immunotherapy drug (tislelizumab) to try to keep the cancer from coming back.
Tianjin, Tianjin MunicipalityAges 17–75 - NCT07024420Recruiting
Sigh breathing during heart surgery with heart-lung machine
This study tests if adding occasional deep breaths (sighs) during heart surgery helps patients recover better after using the heart-lung machine. It is for people having planned (not emergency) heart surgery.
Nanjing, JiangsuAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,629 recruiting pulmonology studies from the U.S. registry right now, out of 10,546 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.