Psychiatry
Mental health clinical trials
Depression, anxiety, and other mental-health and behavioral conditions. We’re tracking 7,779 recruiting studies in this area right now.
By phase
- Not applicable6,422
- Phase 2492
- Phase 1250
- Phase 3240
- Phase 4212
- Phase 1/Phase 294
- Phase 2/Phase 369
Top conditions
- Anxiety387
- Depression382
- Alzheimer Disease338
- Autism Spectrum Disorder239
- Dementia228
- Mild Cognitive Impairment198
- Schizophrenia184
- Major Depressive Disorder173
- Insomnia159
- Cognitive Impairment150
- Alcohol Use Disorder145
- Opioid Use Disorder143
- Stress117
- PTSD105
- Mental Health99
- Autism94
- Mild Cognitive Impairment (MCI)89
- Suicidal Ideation89
Leading sponsors
- VA Office of Research and Development104
- Yale University87
- Massachusetts General Hospital77
- Stanford University68
- Assistance Publique - Hôpitaux de Paris64
- Johns Hopkins University62
- University of California, Los Angeles58
- University of Pennsylvania53
- Karolinska Institutet51
- The University of Hong Kong51
Where studies are running
- California520
- Massachusetts267
- New York255
- Texas209
- Maryland176
- Pennsylvania170
- Florida149
- Alabama118
- Arizona109
- Illinois104
Recruiting studies7,779 total
- NCT05501834Enrolling by invitation
Anxiety study for kids getting arm pins removed
This study tests if a child life specialist can help reduce anxiety when children have pins removed from their arm after a fracture. If your child is between 3 and 10, had a specific arm fracture treated with pins at Boston Children's Hospital, and speaks English, they may be eligible.
Boston, MassachusettsAges 3–10 - NCT05471960Recruiting
Brain training study in people with REM sleep behavior disorder
This study looks at how the brain changes (“neuroplasticity”) in people diagnosed with isolated REM sleep behavior disorder (iRBD) using brain stimulation and other testing. Results may help researchers understand brain differences in iRBD and guide future treatments.
Minneapolis, MinnesotaAges 21–75 - NCT05464888Recruiting
Animal-assisted therapy for kids’ dental visits
This study tests whether working with a trained animal can make dental checkups and cleanings easier for children ages 4 to 8. It may help reduce fear and improve how kids tolerate routine dental care.
Chapel Hill, North CarolinaAges 4–8 - NCT05477862Enrolling by invitation
Improvised music for Alzheimer's anxiety
This study looks at how creating music in the moment (improvisation) affects anxiety and brain function in people with mild to moderate Alzheimer's disease. It may help reduce agitation and improve quality of life.
Chicago, IllinoisAges 55–100 - NCT05473013Recruiting
Digital app for binge eating self-monitoring
This study tests a smartphone app that helps you track your eating episodes. It is designed to improve your skills in managing binge eating, and it is done remotely from home.
Wilmington, DelawareAges 18–65 - NCT05491551Recruiting
Alcohol training program to help you cut back or quit
This study tests a structured training program for young adults who’ve been drinking heavily, to help them reduce drinking or quit. You’ll be asked to complete daily short check-ins and follow study instructions, and you may be randomly assigned to different parts of the program.
Berkeley, CaliforniaAges 18–26 - NCT05494398Enrolling by invitationPhase 2/Phase 3
Testing N-acetylcysteine for autism symptoms
This study looks at whether N-acetylcysteine (NAC), a supplement/medication, can help autism-related symptoms by trying to target brain chemistry. You may be able to join if you previously took part in a related NAC study and can keep your usual medications steady.
Stanford, CaliforniaAges 3–13 - NCT05501678RecruitingPhase 2
Diphenhydramine to help sleep in autistic children
This Phase 2 study tests whether diphenhydramine improves sleep in children with autism who have significant sleep problems. It requires sleep monitoring (watch data and sleep testing) and checking for side effects to see if the treatment is safe and helpful.
Stanford, CaliforniaAges 8–17 - NCT05487911Recruiting
Brain stimulation for depression
This study uses a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) to treat depression. It may help reduce depressive symptoms for people who have not found relief from other treatments.
Houston, TexasAges 18–64 - NCT05489068Recruiting
Motivational interviewing approach for people starting addiction treatment
This study compares two ways of having conversations when you begin outpatient addiction treatment. It tests whether a motivational interviewing style at intake improves your engagement and involvement in your care.
Albuquerque, New MexicoAges 18 years+ - NCT05500170Recruiting
Study of nicotinamide riboside for sleep and thinking
This trial tests whether nicotinamide riboside can improve sleep quality and help with thinking and memory. You may be invited if your sleep is poor and you do not show signs of dementia on a brief mental test.
Buffalo, New YorkAges 65–85 - NCT05461092RecruitingEarly Phase 1
Nerve blocks to improve pain control after spinal fusion
This early-stage study tests whether a regional nerve block can improve pain control and recovery for older adults having elective lumbar spinal fusion. If you qualify, you may receive a special pain-control injection during surgery to reduce opioid needs and improve recovery comfort.
Iowa City, IowaAges 65 years+ - NCT05497115Recruiting
Care model to improve access to mental health after trauma
This trial tests a practical care plan to help people get mental health support after a traumatic injury, especially if screening suggests risk for PTSD or depression. It may help you connect faster to the right kind of treatment after your injury.
Washington, VirginiaAges 16 years+ - NCT05494684Recruiting
Nature-based relaxation for children during blood tests
This study tests whether a nature-based activity can help children aged 5 to 9 feel calmer and less stressed during a blood draw. It aims to make the experience more comfortable for children with long-term illnesses.
OuluAges 5–9 - NCT05474989RecruitingPhase 2
LSD-assisted therapy for alcohol use disorder
This Phase 2 trial studies whether an LSD treatment approach, combined with study procedures, can help people with moderate-to-severe alcohol use disorder cut down or stop drinking. It may help reset patterns around cravings and drinking, but it also requires careful safety screening.
BaselAges 25 years+ - NCT05490589Recruiting
Parenting program for parents affected by alcohol use
This trial tests a structured parenting program for parents of children ages 4 to 12 when the parent (or spouse) has an alcohol use disorder. It may help families by supporting parenting skills and improving day-to-day family functioning.
BrestAges 18 years+ - NCT05477004Enrolling by invitation
Study of ketamine infusions for ongoing chronic pain
This study is observing people with chronic pain who are getting ketamine infusions at Stanford. You may help by completing email surveys about how you feel, which can help the team understand the treatment’s impact.
Stanford, CaliforniaAges 18 years+ - NCT05483426Recruiting
Sexual addiction in men in prison
This study looks at how common sexual addiction is among men in a prison in France. It involves filling out questionnaires to help understand this condition better.
ToulouseAges 18–65 - NCT05492422Recruiting
Training program for children with ADHD and their parents
This trial tests whether a structured “executive skills” training program for kids with ADHD, plus parent training, can improve attention and behavior. It includes both parent and teacher feedback to make sure symptoms are present in everyday settings.
Tallahassee, FloridaAges 8–12 - NCT03701581RecruitingPhase 2/Phase 3
4-aminopyridine to help erections after prostate nerve surgery
This trial tests whether a medicine called 4-aminopyridine (4AP) can help recover or protect erectile function after “nerve-sparing” prostate surgery. It’s for men with early-stage, non-spread prostate cancer who are scheduled for robotic prostate surgery and have good baseline erections.
Tucson, ArizonaAges 45–75 - NCT05117255Recruiting
Online therapy study for anxiety in residential alcohol treatment
This study tests an internet-based, interactive version of cognitive behavioral therapy (CBT) for anxiety symptoms. It’s designed for people getting mainly alcohol-focused treatment in a residential program, to see if the online approach works and is feasible for you.
Minneapolis, MinnesotaAges 18–65 - NCT05441280RecruitingPhase 2
Pimavanserin to improve sleep in veterans with PTSD
This Phase 2 trial studies pimavanserin, a medicine meant to improve insomnia, in veterans who also have PTSD. It may help reduce problems with falling asleep, staying asleep, or waking too early that affect daytime functioning.
Houston, TexasAges 18–64 - NCT05414708Recruiting
Art therapy for veterans with PTSD symptoms
This study tests whether art therapy can improve emotional well-being in military members who have significant PTSD symptoms. You would answer questionnaires and likely take part in art-making sessions as part of the treatment being studied.
Bethesda, MarylandAges 18–64 - NCT05423444Recruiting
Therapy for PTSD in teens using brain connectivity imaging
This study looks at how well PTSD-focused therapy changes brain “connectivity” patterns in adolescents. It may help your care team understand which teens benefit most from therapy.
San Antonio, TexasAges 12–17
Common questions
- How many mental health clinical trials are recruiting?
- Clin2 is tracking 7,779 recruiting psychiatry studies from the U.S. registry right now, out of 12,461 we cover in this area in total.
- What does “Mental health” cover here?
- Depression, anxiety, and other mental-health and behavioral conditions. We group each study into mental health based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mental health trial near me?
- Use the search to filter mental health studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.