Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,962 recruiting studies in this area right now.
By phase
- Not applicable1,544
- Phase 2144
- Phase 384
- Phase 182
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma74
- Periodontal Diseases50
- Dental Caries46
- Head and Neck Cancer35
- Gingivitis34
- Oral Cancer32
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Maryland21
- Massachusetts21
- Florida20
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,962 total
- NCT07409571Recruiting
Gum graft healing after surgery on the palate
This study is testing how well the roof of your mouth heals after a gum graft procedure. It aims to find better ways to help this area heal faster and more comfortably.
Kahramanmaraş, KahramanmaraşAges 18 years+ - NCT07409896Recruiting
Comparing two numbing shots for painful lower first molars
This study compares two numbing methods for severe tooth pain (pulpitis) in a lower first molar. If you have a tooth that needs a root canal and the pain lingers after cold, this trial may help determine which anesthetic works better for you.
Rawalpindi, Punjab ProvinceAges 18–55 - NCT07410351Recruiting
Periodontal risk self-assessment for Saudi adults
This trial is creating a simple online tool to help you assess your risk for gum disease. If you join, you will answer a questionnaire and have a quick gum check at the same visit.
Abhā, 'Asir RegionAges 18 years+ - NCT07410156Recruiting
Comparing treatments for dark gums
This trial tests a new technique using tiny needles and a plant extract (silymarin) to lighten dark gums, and compares it to laser and scalpel methods.
Al FayyumAges 18 years+ - NCT07409558Recruiting
3D scan study for gum improvement after surgery
This study uses 3D digital scans to measure gum tissue changes after a gum grafting procedure. It may be helpful for people with receding gums on their lower front teeth.
Kahramanmaraş, KahramanmaraşAges 18 years+ - NCT07414498Recruiting
Bacteria in gum surgery for implant and tooth infections
This study looks at the bacteria living in deep gum pockets around implants or teeth during different types of gum surgery. It may help determine which surgical approach is best for your kind of gum infection.
Münster, North Rhine-WestphaliaAges 18–80 - NCT07410442Recruiting
Distal shoe safety guidelines for kids
This study looks at how safe and well-tolerated a dental device called a distal shoe is for children who need it. It will help create better care guidelines for kids getting this treatment.
Gainesville, FloridaAges 3–9 - NCT07410780Recruiting
Pain after root canal with two different sealers
This trial compares two types of root canal filling materials—bioceramic and calcium hydroxide—to see which one causes less pain after the procedure. If you have a tooth with a live but inflamed nerve, you may be able to join.
Rawalpindi, Punjab ProvinceAges 18–40 - NCT07412314Recruiting
Proton Therapy for Recurrent Nasopharyngeal Cancer
This trial uses proton therapy (a precise type of radiation) to treat people whose nasopharyngeal cancer has come back. It aims to see if this treatment can help control the cancer while limiting side effects.
Guangzhou, GuangdongAges 18 years+ - NCT06627790RecruitingPhase 3
Herbal mouthwash for tooth sensitivity
This study tests a herbal mouthwash containing potassium nitrate against a potassium oxalate mouthwash to see which better reduces tooth sensitivity. If you have sensitive teeth, you may be eligible to try a new rinse that could help reduce pain.
Pune, MaharashtraAges 18–60 - NCT06813040Recruiting
TMS therapy for jaw and face pain
This trial tests if repetitive transcranial magnetic stimulation (a non-invasive brain stimulation technique) can reduce long-lasting jaw and face pain caused by temporomandibular disorders. It might help people who have had pain for over six months and rate their pain as high.
CoimbraAges 18 years+ - NCT07406360RecruitingPhase 3
Combined MMR and chickenpox vaccine booster for children
This study tests a combined vaccine that protects against measles, mumps, rubella, and chickenpox (varicella) in one shot. It's for healthy children who have already had their first dose of chickenpox and MMR vaccines, to see if this booster is safe and works well.
Birmingham, AlabamaAges 1.3 years–6 years - NCT07403006Recruiting
Comparing two gum recession treatments for better results
This trial looks at two ways to clean the tooth root before a common gum graft procedure. One method uses a special powder and water spray, the other uses hand tools. The goal is to see if one leads to better gum coverage.
Warsaw, MazowszeAges 18–60 - NCT07401641Recruiting
Pain control study for oral cancer surgery
This study tests two different pain medicines (dezocine or nalbuphine) combined with sufentanil to see which helps better control pain after oral cancer surgery with free flap reconstruction. It also looks at side effects and how well the transplanted tissue survives.
Guangzhou, GuangdongAges 18–70 - NCT07399197Recruiting
Tracking tooth movement after pulling in upper canine
This trial uses 3D imaging to measure bone and root changes when pulling an upper canine that sticks out toward the cheek into its proper position. It may help doctors understand how to treat this condition better.
Sanaa, Sana'aAges 12 years+ - NCT07406867Recruiting
Can photos and bitewings detect gum disease?
This study tests whether photos, X-rays, and other non-invasive methods can identify gum disease as accurately as a clinical exam. It may help patients avoid needles or probing.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07400471RecruitingEarly Phase 1
Pain relief before root canal: a medicine combination
This trial tests whether a combination of pain medicines given before a root canal can lower pain afterward. It is for people who have moderate to severe tooth pain and are healthy enough for standard treatment.
Chittagong, ChattogramAges 18 years+ - NCT07398898Recruiting
Can glasses and headphones reduce dental anxiety?
This study tests whether special glasses that show relaxing images and noise-cancelling headphones can help adults feel less anxious during common dental procedures like cleanings, fillings, or extractions.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT07402720Recruiting
Brush vs bur for gum color treatment
This trial compares two methods to lighten dark gums caused by melanin: a polishing brush and a ceramic bur. It will help find which works better and is safer for people with gum pigmentation.
CairoAges 18–40 - NCT07400328RecruitingPhase 2
Stem cell injection to prevent severe mouth sores in transplant
This trial is testing a single injection called Amimestrocel to prevent severe mouth sores in people getting a stem cell transplant. The study is for adults who are receiving high-dose conditioning with total body irradiation or melphalan, which often cause painful mouth inflammation.
Suzhu, JiangsuAges 18–65 - NCT07405905Recruiting
Comparing mini implant placements for fixing upper teeth overbite
This study tests two ways of placing small temporary anchors (mini implants) in the jaw to help pull upper front teeth back into a better position. It is for patients who have finished growing and have a Class II overbite, to see which anchor location works best.
Rohtak, HaryanaAges 18–30 - NCT06018701RecruitingEarly Phase 1
Dental device secured with bone cement for missing teeth
This trial tests a special dental device that is cemented into the jawbone for people missing one or more teeth. It may be a good option if your jawbone is dense enough and you don't have serious other health issues.
Kathmandu, BagmatiAges 18–80 - NCT06826456Recruiting
Laser treatment to prevent cavities in children's molars
This study tests whether a special laser (Er,Cr:YSGG) can prevent cavities in the deep grooves of children's permanent back teeth. It is for children ages 6–12 who are calm during dental visits and have healthy, groove-filled molars without visible cavities.
AlexandriaAges 6–12 - NCT06827665RecruitingPhase 1/Phase 2
Dentin Bone Graft for Jawbone Preservation After Tooth Extraction
This trial tests a new type of bone graft made from donated teeth to help preserve the jawbone after multiple teeth are pulled. It aims to see if this natural material helps the bone heal better than standard treatments.
AmmanAges 18–60
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,962 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,741 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.