Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,764 recruiting studies in this area right now.
By phase
- Not applicable3,111
- Phase 4251
- Phase 2144
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University97
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad26
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- Illinois38
- North Carolina38
Recruiting studies3,763 total
- NCT07482371Recruiting
Scooping vs. cupping for stiff elbows in kids
This study compares two gentle therapies—scooping mobilization and dynamic cupping—to see which better helps children regain elbow movement after a fracture. It may be an option for kids who have had their elbow in a cast or splint for at least 3 weeks.
Lahore, Punjab ProvinceAges 6–13 - NCT07482709RecruitingPhase 1/Phase 2
Nerve block with or without ketamine for hysterectomy pain
This study compares two ways to reduce pain after a hysterectomy: a standard nerve block with bupivacaine (a numbing medicine) versus the same block plus ketamine (a medicine that can boost pain relief). The goal is to see if adding ketamine provides better comfort after surgery.
Karachi, SindhAges 25–65 - NCT07483190Recruiting
Nerve block for pain after laparoscopic hysterectomy
This study tests a nerve block called M-TAPA to reduce pain after laparoscopic hysterectomy. It may help you need less pain medicine and recover more comfortably.
IstanbulAges 18–70 - NCT07483216Recruiting
Exercise study for women with fibromyalgia
This trial tests a special type of strength exercise (isokinetic exercise) to see if it can help women with fibromyalgia feel better and move easier. It may be a good fit if you are generally stable on your current treatments and able to exercise safely.
Valladolid, ValladolidAges 18 years+ - NCT07484815Recruiting
Virtual reality for pain during egg freezing
This study tests whether using a virtual reality (VR) headset during egg freezing can help reduce pain. If you are having your eggs retrieved to preserve your fertility, you may be able to take part and wear a VR device to see if it makes the procedure more comfortable.
JerusalemAges 18–45 - NCT07485387Recruiting
Korean cognitive aging study using smartphone app
This study looks at how thinking and memory change as people get older. It uses a smartphone app to track these changes over time in healthy older adults living in South Korea.
Seoul, Select One...Ages 60 years+ - NCT07669961Recruiting
Distraction cards vs toy squeezing for kids getting shots
This trial compares using distraction cards or a squeezable toy to help children aged 4–7 feel less pain and fear during a routine vaccination shot.
Mersin, ProvinceAges 4–7 - NCT05415384Recruiting
Cryotherapy plus surgery for broken ribs
This trial tests whether adding cryotherapy (freezing treatment to the injury area) to standard surgery for broken, displaced ribs can improve recovery. It’s for adults with multiple broken ribs who are getting a surgical stabilization procedure soon after injury.
Winston-Salem, North CarolinaAges 18–80 - NCT07674407Recruiting
Fear of movement and physical function in back pain
This study looks at how fear of movement relates to physical function in people with long-term low back pain from a herniated disc. It may help understand how to improve daily activities.
IstanbulAges 18–65 - NCT05197946Recruiting
Imaging study comparing brain changes in cerebral palsy and typical people
This study uses surveys and brain imaging (MRI) to look for patterns that match chronic pain in people with cerebral palsy, and compares them with people without cerebral palsy. It may help researchers better understand what brain features relate to chronic pain.
Baltimore, MarylandAges 8 years+ - NCT07672873Recruiting
Steroid injection for tooth nerve pain during root canal
This trial tests whether a single injection of dexamethasone (a steroid) near the nerve of a painful lower molar can improve pain relief during a root canal. It's for people with severe tooth nerve pain who haven't taken pain meds recently.
IstanbulAges 18–65 - NCT06216717Recruiting
Study of electrode location for brain stimulation in chronic pain
This study looks at where electrodes are placed in the brain for people who have a device that stimulates the motor cortex to treat chronic nerve pain. The goal is to help improve how these devices are positioned for better pain relief.
Nice, Alpes MaritimesAges 18 years+ - NCT07596823Recruiting
Blood counts and nerve pain relief after a nerve block
This study looks at how blood cell counts change when you receive a nerve-blocking injection for neuropathic pain (nerve damage pain). Researchers want to understand if these blood changes can predict how well the injection will help your pain.
Ankara, CankayaAges 18 years+ - NCT07668648Recruiting
Two nerve blocks for shoulder surgery pain relief
This study compares two types of nerve blocks to reduce pain after shoulder surgery. One block is placed near the neck (interscalene) and the other is placed further away (serratus posterior superior intercostal plane block). The goal is to see which works better and has fewer side effects.
Bursa, NilüferAges 18–75 - NCT07487610Recruiting
Pain and health in adults 80 and older
This study looks at the link between nerve pain (neuropathic pain) and overall health in people aged 80 and older. It aims to understand how pain affects daily life and aging.
EdirneAges 80 years+ - NCT07487649Recruiting
Treatment response in headache from medication overuse
This trial looks at how well people respond to treatment when their headaches are caused by taking too much pain medicine. It may help if you have migraines or tension headaches and you use triptans or NSAIDs often.
EdirneAges 18–65 - NCT07488832Recruiting
Lidocaine for pain control after spine surgery
This trial tests whether giving lidocaine through an IV during surgery can help reduce pain after lumbar fusion surgery. It may lead to less need for other pain medicines and a smoother recovery.
AnkaraAges 18–65 - NCT07488936Recruiting
How low back pain types affect pain and quality of life after failed back surgery
This study looks at how different types of low back pain affect pain severity and quality of life in people who still have pain after back surgery. It aims to help doctors better understand and treat your pain.
Konya, SelçukluAges 18 years+ - NCT07489001Recruiting
Comparing opioid-free to standard anesthesia for back surgery
This study compares two types of anesthesia for lower back surgery: one that uses opioids and one that does not. The goal is to see which approach controls pain better with fewer side effects.
Istanbul, MaltepeAges 18–75 - NCT07489937Recruiting
Arm exercise effects on the shoulder tendon
This study compares how two different arm exercises affect the shoulder tendon (supraspinatus) in people with and without shoulder pain. It may help find better ways to exercise without causing injury.
Gainesville, FloridaAges 18–45 - NCT07491549Recruiting
Pain education group therapy for chronic pain
This trial tests if group education about pain can help people with chronic pain move more, feel better, and have less fear of movement. It's looking for adults whose pain has lasted more than 3 months and affects their daily life.
Tartu, TartuAges 16–65 - NCT07493213Recruiting
Ultrasound-guided shoulder injections for frozen shoulder
This study tests whether ultrasound-guided injections into the shoulder can improve pain and movement in people with frozen shoulder. It may help if you have had shoulder pain for at least 3 months and other treatments haven't worked well.
Konya, SelçukluAges 18–75 - NCT07493226Recruiting
NSAIDs for Frozen Shoulder Pain Study
This study tests different types of nonsteroidal anti-inflammatory drugs (NSAIDs) to see which works best for people with frozen shoulder. It may help you if you have ongoing shoulder pain and stiffness without other shoulder injuries.
Konya, SelçukluAges 18–75 - NCT07495761Recruiting
Central sensitization signs in adults with autism
This study looks at whether adults with autism (without intellectual disability) experience central sensitization, a condition where the nervous system becomes overly sensitive to stimuli. It aims to understand how common this is and why it matters for treatment.
Grenoble, IsereAges 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,764 recruiting pain medicine studies from the U.S. registry right now, out of 6,842 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.