Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,764 recruiting studies in this area right now.
By phase
- Not applicable3,111
- Phase 4251
- Phase 2144
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University97
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad26
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- Illinois38
- North Carolina38
Recruiting studies3,763 total
- NCT07453641Recruiting
White Noise for Calm Infants During Needle Procedures
This study tests if playing white noise helps calm babies aged 1-3 months during common needle procedures like blood draws or IV placement, by reducing crying time. It offers a simple, drug-free way to ease discomfort.
IstanbulAges 1 month–3 months - NCT07454993Recruiting
Music during colonoscopy study
This trial tests whether listening to music during a colonoscopy can make the procedure more comfortable. If you are having a routine colonoscopy without deep sedation, you may be able to join.
Esbjerg, Region SydAges 18 years+ - NCT07455565Recruiting
Pain monitoring with ANI after lumbar spine surgery
This study tests a new way to monitor pain after lower back surgery using a device called ANI, which tracks your body's response to pain. The goal is to see if this method helps doctors give you better pain relief.
Antalya, AntalyaAges 18–65 - NCT07457086Recruiting
Breathing technique for better sleep and recovery after bladder surgery
This trial tests whether a simple breathing pattern called 4-7-8 can help you sleep better, hurt less, and recover faster after transurethral resection of the bladder (a procedure to remove bladder tumors).
Mersin, TurkeyAges 18 years+ - NCT07457788Recruiting
Forest Sounds During Chest Tube Removal
This study tests whether listening to virtual reality forest sounds can help people feel more comfortable while a chest tube is taken out. It may reduce pain or anxiety during this short procedure.
Istanbul, KadıköyAges 18 years+ - NCT07459400Recruiting
Mud therapy for young adults with scoliosis back pain
This study tests whether adding mud therapy (peloidotherapy) to standard scoliosis exercises helps reduce pain and improve function in young adults with mild to moderate scoliosis. It may be a good fit if you have idiopathic scoliosis and ongoing back pain.
Istanbul, GaziosmanpasaAges 20–40 - NCT07462364Recruiting
Using a kaleidoscope or cartoons for dental treatment in children
This study tests whether using a kaleidoscope or watching cartoons can help calm children during dental treatment that requires a numbing shot. It aims to find a simple way to make dental visits less scary.
Diyarbakır, DiyarbakırAges 7–12 - NCT07463729Recruiting
Back pain study using biofeedback training
This trial tests a stabilization training program using biofeedback (a device that shows you how your muscles are working) to treat chronic low back pain. It may help you strengthen the muscles supporting your spine and reduce your pain.
Tarnów, MałopolskaAges 30–65 - NCT07465991Recruiting
Online insomnia therapy for fibromyalgia and activity
This study tests if an online therapy program for insomnia (using cognitive behavioral therapy, or CBT) can help people with fibromyalgia sleep better and be more physically active. If you have fibromyalgia and trouble sleeping, this treatment may improve your pain and daily function.
OxfordAges 18 years+ - NCT07467070Recruiting
Pilates for posture, core strength, and flexibility in young adults with low back pain
This study tests whether a 6-week Pilates program can improve posture, core strength, and flexibility in young adults with mild to moderate low back pain that has no clear cause. It could help you learn exercises to ease your pain and strengthen your back.
Lahore, Punjab ProvinceAges 18–25 - NCT07467551Recruiting
Pain scale study for patients on breathing machines
This study tests a pain scale for patients who are on a breathing machine and cannot speak. It aims to help doctors better recognize pain in these patients.
IstanbulAges 18–85 - NCT07467577Recruiting
Does washing the belly during hysterectomy reduce pain?
This trial tests whether rinsing the belly with clean fluid during a hysterectomy (done through the vagina with small cameras) can lower pain after surgery. It may help if you are having your uterus removed for a non-cancer reason.
MuğlaAges 18–80 - NCT07468097Recruiting
How metabolism affects pain in women with lipedema
This study looks at how metabolic health (like blood sugar and thyroid function) may influence pain and sensitivity in women with lipedema. It aims to better understand these links to improve treatment approaches.
Istanbul, PendikAges 18 years+ - NCT07472296Recruiting
Comparing nerve blocks for heart surgery pain relief
This trial compares different types of nerve blocks to see which works best for managing pain after heart surgery through the breastbone. It may help reduce the need for strong pain medications.
Bursa, NilüferAges 18–80 - NCT07472842Recruiting
Study on outcomes for endometriosis in emergency care
This study follows women who come to a specific hospital's emergency department with known endometriosis or symptoms that might be endometriosis, to learn more about their health outcomes over time.
CréteilAges 18 years+ - NCT07472959RecruitingPhase 4
Morphine for pain after heart bypass surgery
This study tests whether giving morphine during coronary artery bypass surgery can help control pain after the operation. It is for people having planned heart bypass surgery who are moderately sick and not already on strong pain medicines.
Istanbul, Outside of the USAges 18–80 - NCT07473609Recruiting
Studying epidurals that don't work well during labor
This study looks at epidurals that don't work well during labor. It aims to understand why some epidurals fail, which could help improve pain relief for mothers.
MadridAges 18 years+ - NCT07474662Recruiting
Online vs. in-person physiotherapy for jaw muscle pain
This trial compares online physiotherapy sessions with face-to-face visits to see which works better for treating jaw muscle pain (myalgia). It aims to find a more convenient way to get care for this common condition.
Budapest, Pest CountyAges 18 years+ - NCT07477236Recruiting
Sleep and headache management study
This study tests a natural supplement to help adults manage everyday headaches and improve sleep. You will take the supplement daily and fill out weekly surveys and a daily log.
New York, New YorkAges Any age - NCT07478614Recruiting
Study of treatments for adenomyosis pain and heavy bleeding
This study follows people with adenomyosis to see which treatments work best for pain and heavy bleeding. It may help doctors find better ways to manage symptoms.
PotenzaAges 20–50 - NCT07479082Recruiting
Ear nerve stimulation for headache after aneurysm coiling
This trial tests whether a gentle electrical device placed on your ear (called transcutaneous auricular vagus nerve stimulation) can help prevent or reduce headaches that sometimes happen after a procedure to treat an unruptured brain aneurysm. If you're scheduled for stent-assisted coiling or flow diverter treatment, this study may offer a non-drug option to manage post-surgery pain.
Beijing, Beijing MunicipalityAges 18–80 - NCT07479199Recruiting
Radiofrequency ablation and radiation for painful spine tumors
This trial tests a treatment that uses heat (radiofrequency ablation) and radiation to relieve pain from tumors in the spine. It may help if you have cancer that has spread to your upper or lower back and you have moderate to severe pain.
Chapel Hill, North CarolinaAges 18 years+ - NCT07479602RecruitingPhase 4
Medicine via nose for less pain after tonsil surgery in kids
This trial tests whether giving two medicines (dexmedetomidine and esketamine) through the nose can help children ages 3-7 have less pain after their tonsil or adenoid surgery. The goal is to find a better way to manage pain without using strong drugs.
Beijing, Beijing MunicipalityAges 3–7 - NCT07480278Recruiting
Pain relief after back surgery: two injections compared
This trial tests two different injection methods to see which one provides better pain relief after lower back surgery. If you are having a microdiscectomy, this study may help determine the best way to manage your post-operative pain.
Bursa, NilüferAges 18–65
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,764 recruiting pain medicine studies from the U.S. registry right now, out of 6,842 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.